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| 1 | 焦虑抑郁对慢性阻塞性肺疾病急性加重和住院的影响显示文摘本研究旨在通过为期1年的多中心、前瞻性随访评价焦虑抑郁作为独立危险因素对慢性阻塞性肺疾病急性加重和住院的影响。研究随机选取来自北京10所综合医院的491例稳定期COPD患者,所有患者进入研究前均签署知情同意书。研究持续1年,开始及结束时进行现场问卷调查,记录患者的个人资料、1年前COPD急性加重发作次数和住院次数等。应用认证的中文版焦虑一抑郁量表(HADS)评价焦虑、抑郁状态;应用5级医学研究呼吸困难评分法(MRCQ)评价呼吸困难; | 徐婉宁 Jean PC Stanley S 林英翔 杨汀 Robert P 王辰 Jean B | 2010 | 中华结核和呼吸杂志2010,33,5: | 4 |
| 2 | Diabetic nephropathy in Africa:A systematic review显示文摘AIM:To determine the prevalence and incidence of diabetic nephropathy in Africa.METHODS:We performed a systematic narrative review of published literature following the MOOSE Guidelines for Meta-Analysis and Systematic Reviewsof Observational Studies.We searched Pub MedMEDLINE for all articles published in English and French languages between January 1994 and July 2014 using a predefined strategy based on the combination of relevant terms and the names of each of the 54 African countries and African sub-regions to capture the largest number of studies,and hand-searched the reference lists of retrieved articles.Included studies reported on the prevalence,incidence or determinants of chronic kidney disease(CKD) in people with diabetes within African countries.RESULTS:Overall,we included 32 studies from 16 countries;two being population-based studies and the remaining being clinic-based surveys.Most of the studies(90.6%) were conducted in urban settings.Methods for assessing and classifying CKD varied widely.Measurement of urine protein was the most common method of assessing kidney damage(62.5% of studies).The overall prevalence of CKD varied from 11% to 83.7%.Incident event rates were 94.9% for proteinuria at 10 years of follow-up,34.7% for endstage renal disease at 5 years of follow-up and 18.4% for mortality from nephropathy at 20 years of followup.Duration of diabetes,blood pressure,advancing age,obesity and glucose control were the common determinants of kidney disease.CONCLUSION:The burden of CKD is important among people with diabetes in Africa.High quality data from large population-based studies with validated measures of kidney function are still needed to better capture the magnitude and characteristics of diabetic nephropathy in Africa. | Jean Jacques N Noubiap Jashira Naidoo Andre P Kengne | 2015 | World Journal of Diabetes2015,6,5: | 3 |
| 3 | 呼吸音分析技术用于心源性和非心源性呼吸困难的鉴别诊断显示文摘目的 临床上心力衰竭,慢性阻塞性怖病和哮喘急性加重时均可以通过听诊器发现异常呼吸音,目前为止尚不能对以上呼吸音进行定量分析。对于就诊于急诊科的呼吸困难患者,鉴别诊断其发生原因对于临床治疗措施和预后关系密切。本研究的目的就是应用计算机辅助的呼吸音分析技术对心源性和非心源行呼吸困难时的呼吸音进行定量分析,同时评价其临床应用价值。方法本实验为前瞻性临床研究,应用呼吸音分析记录装置记录患者呼吸过程中所产生的呼吸音,通过计算机辅助技术将呼吸音转化成图像。收集因急性呼吸困难来北京大学第三医院急诊就诊的患者59人,根据患者最终出院诊断分为3组:急性心力衰竭患者22人,慢性阻塞性肺病急性加重期患者19人,哮喘急性发作患者18人。选择同期健康志愿者20人作为对照组。对三组患者的呼吸音图像进行定量分析,分析指标为吸气相最大呼吸音能量图面积和最大吸气相/最大呼气相能量比值。组间比较采用t检验。结果健康对照组、心力衰竭组、慢性阻塞性肺病急性加重期患者和哮喘急性发作患者的吸气相最大呼吸音能量图面积分别为:(76.2±4.5),(67.6±6.7),(72.2±7.6)和(52±11.7)千像素(P〈0.01)。健康对照组、心力衰竭组、慢性阻塞性肺病急性加重期患者和哮喘急性发作患者的吸气相最大呼吸音能量图左右侧面积之比分别为1:1、1:1、1:1和1:0.4。健康对照组、心力衰竭组、慢性阻塞性肺病急性加晕期患者和哮喘急性发作患者的最大吸气相/呼气相能量峰值比值分别为:(6.3±5.2),(5.6±4.0),(2.0±2.2)和(0.3±0.3),P〈0.01:结论与健康对照相比较,心力衰竭患者组的吸气相最大呼吸音能量图面积明显缩小,吸气相最大呼吸音能量图左右面积之比及最大吸气相/最大呼气相能量比值尢差别;与健康对照相比较,慢性阻塞性肺病患者的吸气相最大呼吸音能量图面积无差别,吸气相最大呼吸音能量图左右面积之比无差别,最大吸气相/最大呼气相能量比值明显缩小;与健康对照相比较,哮喘患者的吸气相最大呼吸音能量图面积明显缩小,吸气相最大呼吸音能量图左右面积不对称,最大吸气相/最大呼气相能量比值明显缩小。以上图像特点对鉴别心力衰竭、阻塞性肺病和哮喘所引起的呼吸困难有帮助。 | 王真 Smith Jean Richard P Dellinger | 2009 | 中华急诊医学杂志2009,18,12: | 3 |
| 4 | Improved clinical outcome using polytetrafluoroethylene-coated stents for tips: Results of a randomized study显示文摘 | Christophe Bureau Juan carlos Garcia-Pagan Philippe Otal Gilles Pomier-Layrargues Valérie Chabbert Carlos Cortez Pierre Perreault Jean marie Péron Juan G. Abraldes Louis Bouchard José Ignacio Bilbao Jaume Bosch Hervé Rousseau Jean pierre Vinel | 2004 | Gastroenterology2004,,2: | 3 |
| 5 | Comparison between UV spectroscopy and nirs to assess humification process during sewage sludge and green wastes co-composting显示文摘 | Remy Albrecht Jean Le Petit Gérard Terrom Claude Périssol | 2010 | Bioresource Technology2010,,6: | 2 |
| 6 | Advances in the Treatment and Outcome of Brainstem Cavernous Malformation Surgery: A Single-Center Case Series of 300 Surgically Treated Patients显示文摘 | Adib A Abla Gregory P Lekovic Jay D Turner Jean G de Oliveira Randall Porter Robert F Spetzler | 2011 | Neurosurgery2011,,2: | 2 |
| 7 | Risk factor extrauterine pregnancy in women using an intrauterine device显示文摘 | Jean A Bouyer P | 2007 | Fertil Steril2007,74,5: | 1 |
| 8 | Heuristic approaches to vehicle routing with backhauls and time windows显示文摘 | Sam R T Jean Y P Tong S | 1996 | Computers and Operations Research1996,23,11: | 1 |
| 9 | Predicting loin 2 eye area from ultrasound and grading probe measurements of fat and muscle depths in pork carcasses显示文摘 | Pomar C l~ ivest J Jean dit Bailleul P | 2001 | Can J Anim Science2001,81,: | 1 |
| 10 | ZnO Nanowire Arrays for Enhanced Photocurrent in PbS Quantum Dot Solar Cells显示文摘 | Jean J Chang S Brown P R | 2013 | Advanced Materials2013,25,20: | 1 |
| 11 | A Watermarking-Based Method for Informed Source Separation of Audio Signals with a Single Sensor显示文摘 | MATHIEU P LAURENT G JEAN M B | | 0,,06: | 1 |
| 12 | Efficient combination of recyclable task specific ionic liquid and microwave dielectric heating for the synthesis of lipophilic esters显示文摘 | Atef A Jean P B | 2005 | Organic Process Research & Development2005,9,2: | 1 |
| 13 | Cell - cycle - dependent expression of transforming growth factor β type Ⅰ receptor correlates with differential proliferative effects if TGF - β1 in articular chondrocytes显示文摘 | Nathalie F Jean - Pierre P | 1998 | Experimental cell research1998,243,: | 1 |
| 14 | A variational approach for the study outdoor sound propagation and application to railway noise 显示文摘 | Jean P | 1998 | Journal of Sound and Vibration1998,212,2: | 1 |
| 15 | Effcient combination of recyclable task specific ionic liquid and microwave dielectric heating for the synthesis of lipophilic esters显示文摘 | Atef A Jean P B | 2005 | Organic Process Research & Development2005,9,: | 1 |
| 16 | FGF-2 and FGF-1 expressed in rat bladder carcinoma cells have similar angiogenic potential but different tumorigenic properties in vivo显示文摘 | JACQEUELINE J JEAN P GINETTE M | 1997 | Ocogene1997,14,6: | 1 |
| 17 | Analog sensor design proposal for laser Doppler velocimetry 显示文摘 | Alain L D Guy P Jean C V | 2004 | IEEE Sensors Journal2004,4,2: | 1 |
| 18 | The clays, Part II: Permeability characteristics显示文摘 | TAVENAS F LEBLOND permeability of natural soft P JEAN P | 1983 | Canadian Geotechnical Journal1983,20,4: | 1 |
| 19 | Development neurotoxicity of industial chemicals 显示文摘 | GRAND JEAN P LANDRIGAN PJ | 2006 | Lancet2006,368,: | 1 |
| 20 | Microbial hydrolysis of methyl aromatic esters by Burkholderia cepacia iso- lated from soil显示文摘 | Geraldine P Danielle V Jean B | 2001 | FEMS Microbiology Ecology2001,37,: | 1 |