|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Gene duplication drove the loss of awn in sorghum.显示文摘Loss of the awn in some cereals including sorghum is a key transition during cereal domestication or improvement that has facilitated grain harvest and storage.The genetic basis for the loss of awn in sorghum during domestication or improvement remains unknown.Here,we identified a transcription factor gene awn1 encoding an ALOG domain,which is responsible for awn loss during sorghum domestication or improvement.awn1 arose from a gene duplication from chromosome 10 that translocated to chromosome 3,recruiting a new promoter from the neighbouring intergenic region filled with'noncoding DNA',and recreating the first exon and intron.The awn1 acquires high expr`ession after duplication and represses the elongation of awns in domesticated sorghum.Comparative mapping revealed a high collinearity at awn1 paralog locus on chromosome 10 across cereals and awn growth and development was successfully reactivated on the rice spikelet by inactivating rice awn1 orthologue.Further RNA-seq and DAP-seq revealed that as a transcription repressor,AWN1 directly bound to the motif in the regulatory regions from three MADS genes related to flower development and two genes DL and LKS2 for the development of awn,downregulated the expressions of these genes,and then repressed the elongation of awn.The preexistence of regulatory elements in the neighbouring intergenic region of awn1 before domestication signified that noncoding DNA may serve as a treasure trove for evolution during adaptation to a changing world.Our results supported that gene duplication can promptly drive the evolution of gene regulatory network. | Leina Zhou Can Zhu Xiaojian Fang Hangqin Liu Shuyang Zhong Yan Li Jiacheng Liu Yang Song Xing Jian Zhongwei Lin | 2021 | Molecular Plant2021，14，11： | 2 |
| 2 | Single-cell RNA sequencing reveals B cell-T cell interactions in vascular adventitia of hyperhomocysteinemia-accelerated atherosclerosis显示文摘Dear Editor Cardiovascular disease(CVD)is the leading cause of death around the world(Truelsen,et al.,2015).Atherosclerosis,the dominant underlying cause of CVD,is a chronic inflam-matory disease characterized by lipid accumulation and immune cell infiltration in plaques and vessels(Weber,et al.,1950).The immune microenvironment is critical for the development of atherosclerosis.Homocysteine(Hcy)is an intermediate product of methionine metabolism,and its ele-vation in plasma(>15μmol/L),known as hyperhomocys-teinemia(HHcy),is an independent risk factor for atherosclerosis.HHcy is more common in Asia because of genetic factors and dietary habits(Huo,et al.,2015).folic acid supplement is one of the most important way to treat HHcy in clinic.Although HHcy potentiates atherosclerosis mainly through endothelial injury and inflammatory activa-tion(Luo,et al.,2016),a comprehensive understanding of the immune microenvironment and potential mechanisms in HHcy-accelerated atherosclerotic aortas(HHcy-AA)is still lacking. | Xiaolong Ma Jiacheng Deng Lulu Han Yuwei Song Yutong Miao Xing Du Guohui Dang Dongmin Yang Bitao Zhong Changtao Jiang Wei Kong Qingbo Xu Juan Feng Xian Wang | 2022 | Protein & Cell2022，13，7： | 2 |
| 3 | Fabrication of Fe Nanoparticles into N-doped Mesoporous Carbon Nanotube Derived from Rice-Like Fe/N-MOF and Its ORR Catalytic Performance for MFC显示文摘The development of non-noble metal oxidation reduction catalysts(ORR)to improve microbial fuel cell(MFC)performance remains extremely challenging.Herein,the nitrogen-doped iron-based porous carbon nanotube Fe/N@MC-T ORR catalysts were derived from Fe/N-MOF by pyrolyzation using acetonitrile as the nitrogen precursor in a low-cost organic solvent.The Fe/N@MC-T catalysts under different pyrolysis temperatures were characterized by SEM,TEM,BET,XRD,and XPS techniques.Fe/N-MOF showed a smooth rice-like structure with a particle size of about 400×50 nm^(2).The Fe species in Fe/N@MC-T mainly exists in the form of zero-valent iron with a small amount of Fe3C.The results of electrochemical tests revealed that the onset and half-wave potentials of Fe/N@MC-700 were 0.89 V and 0.80 V,respectively,which were only slightly lower than those of the commercial Pt/C(0.92 V and 0.82 V).The MFC with Fe/N@MC-700 showed a highest power density of 864.1 mW/m^(2),which was about 2.25 times that of MFC with carbon cloth,and was slightly lower than that of MFC with Pt/C(20%)(1002.0 mW/m^(2)),which demonstrated that the Fe particles wrapped in carbon nanotubes possessed a relatively high ORR activity. | Lu Decheng Wang Wenyi Chang Jiacheng Wang Xueqin Wang Yuanyuan Song Hua | 2021 | China Petroleum Processing & Petrochemical Technology2021，23，2： | 2 |
| 4 | Dy- namic simulation and tests of a three -phase high Tc su- perconducting fault current limiter 显示文摘 | Zhang Jiacheng Gao Zhiyuan Song Naihao | | IEEE Transactions On Applied Superconductivity0，12，1： | 1 |
| 5 | SSJD14101300025726显示文摘 | Bingnan Liu Ying Li Jinzhu Song Lihong Zhang Jiacheng Dong Qian Yang | 2014 | Cellulose2014，，5： | 1 |
| 6 | Study on the role of copper converter slag in simultaneously removing SO_(2)and NO_(x)using KMnO_(4)/copper converter slag slurry显示文摘To achieve'waste controlled by waste',a novel wet process using KMnO_(4)/copper converter slag slurry for simultaneously removing SO_(2)and NO_(x)from acid-making tail gas was proposed.Through the solid-liquid separation for copper slag slurry,the liquid-phase part has a critical influence on removing NO_(x)and SO_(2).Also,the leached metal ions played a crucial role in the absorption of SO_(2)and NO_(x).Subsequently,the effects of single/multi-metal ions on NO_(x)removal was investigated.The results showed that the leached metal from copper converter slag(Al^(3+),Cu^((2+),and Mg^((2+))and KMnO_(4)had a synergistic effect on NO_(x)removal,thereby improving the NO_(x)removal efficiency.Whereas Fe^(2+) had an inhibitory effect on the NO_(x)removal owing to the reaction between Fe^(2+) and KMnO_(4),thereby consuming the KMnO_(4).Besides,SO_(2)was converted to SO_(4)^(2-) completely partly due to the liquid catalytic oxidation by metal ions.The XRD and XPS results indicated that the Fe(Ⅱ)species(Fe_(2)SiO_(4),Fe_(3)O_(4))in copper slag can react with H+ions with the generation of Fe^(2+),and further consumed the KMnO_(4),thereby resulting in a decrease in the NO_(x)removal.The characterization of the slags and solutions before and after reaction led us to propose the possible mechanisms.The role of copper slag is as follows:(1)the alkaline substances in copper slag can absorb SO_(2)and NO_(2)by KMnO_(4)oxidation.(2)copper slag may function as a catalyst to accelerate SO_(2)conversion and improve NO_(x)removal by synergistic effect between leached metal ions and KMnO_(4). | Jiacheng Bao Kai Li Ping Ning Chi Wang Xin Song Yansu Luo Xin Sun | 2021 | Journal of Environmental Sciences2021，33，10： | 1 |
| 7 | Targeting UHRF1-SAP30-MXD4 axis for leukemia initiating cell eradication in myeloid leukemia显示文摘Aberrant self-renewal of leukemia initiation cells(LICs)drives aggressive acute myeloid leukemia(AML).Here,we report that UHRF1,an epigenetic regulator that recruits DNMT1 to methylate DNA,is highly expressed in AML and predicts poor prognosis.UHRF1 is required for myeloid leukemogenesis by maintaining self-renewal of LICs.Mechanistically,UHRF1 directly interacts with Sin3A-associated protein 30(SAP30)through two critical amino acids,G572 and F573 in its SRA domain,to repress gene expression.Depletion of UHRF1 or SAP30 derepresses an important target gene,MXD4,which encodes a MYC antagonist,and leads to suppression of leukemogenesis.Further knockdown of MXD4 can rescue the leukemogenesis by activating the MYC pathway.Lastly,we identified a UHRF1 inhibitor,UF146,and demonstrated its significant therapeutic efficacy in the myeloid leukemia PDX model.Taken together,our study reveals the mechanisms for altered epigenetic programs in AML and provides a promising targeted therapeutic strategy against AML. | Cheng-Long Hu Bing-Yi Chen Zijuan Li Tianbiao Yang Chun-Hui Xu Ruirui Yang Peng-Cheng Yu Jingyao Zhao Ting Liu Na Liu Bin Shan Qunling Zhang Junhong Song Ming-Yue Fei Li-Juan Zong Jia-Ying Zhang Ji-Chuan Wu Shu-Bei Chen Yong Wang Binhe Chang Dan Hou Ping Liu Yilun Jiang Xiya Li Xinchi Chen Chu-Han Deng Yi-Yi Ren Roujia Wang Jiacheng Jin Kai Xue Ying Zhang Meirong Du Jun Shi Ling-Yun Wu Chun-Kang Chang Shuhong Shen Zhu Chen Sai-Juan Chen Xiaolong Liu Xiao-Jian Sun Mingyue Zheng Lan Wang | 2022 | Cell Research2022，32，12： | 1 |
| 8 | Neural network assisted high-spatial-resolution polarimetry with non-interleaved chiral metasurfaces显示文摘Polarimetry plays an indispensable role in modern optics.Nevertheless,the current strategies generally suffer from bulky system volume or spatial multiplexing scheme,resulting in limited performances when dealing with inhomogeneous polarizations.Here,we propose a non-interleaved,interferometric method to analyze the polarizations based on a tri-channel chiral metasurface.A deep convolutional neural network is also incorporated to enable fast,robust and accurate polarimetry.Spatially uniform and nonuniform polarizations are both measured through the metasurface experimentally.Distinction between two semblable glasses is also demonstrated.Our strategy features the merits of compactness and high spatial resolution,and would inspire more intriguing design for detecting and sensing. | Chen Chen Xingjian Xiao Xin Ye Jiacheng Sun Jitao Ji Rongtao Yu Wange Song Shining Zhu Tao Li | 2023 | Light(Science & Applications)2023，12，12： | 0 |
| 9 | Review of Black Start on New Power System Based on Energy Storage Technology显示文摘With the continuous development of new energy generation technology and the increasingly complex power grid environment,the traditional black start scheme cannot meet the requirements of today’s power grid in order to ensure the stable operation of the power system can be restored quickly in the face of large power outages,so a more complete black start scheme needs to be developed to cope with the new power system.With the development of energy storage technology,the limitations of the traditional black-start scheme can be solved by new energy farms with energy storage configuration.Therefore,this paper investigates the problems faced by black-start,the key technologies of energy storage assisted new energy black-start,and introduces the research related to new energy black-start technology to provide reference for future research and application of new energy black-start. | Jin Fan Litao Niu Cuiping Li Gang Zhang He Li Yiming Wang Junhui Li Qinglong Song Jiacheng Sun Jianglong Pan Fangfang Lai | 2023 | Energy Engineering2023，120，12： | 0 |
| 10 | A multiple flame-retardant,early fire-warning,and highly sensitive thread-shaped all-fabric-based piezoresistive sensor显示文摘In the artificial intelligence age,multifunctional and intelligent fireproof fabric-based electronics are urgently needed.Herein,a novel thread-shaped all-fabric-based piezoresistive sensor(denoted as TAFPS)with properties such as flame retardancy,firewarning,and piezoresistivity is proposed,which is composed of an inner nickel-plated fabric electrode,a multifunctional double helix fabric,and an external flame-retardant encapsulation fabric.Owing to the multiple flame-retardant properties of glass fiber tubular fabric,aminated carbon nanotubes(ACNTs),and ammonium polyphosphate,the char residue of the TAFPS reaches40.3 wt%at 800℃.In addition,the heat-sensitive effect of ACNTs during combustion causes a rapid decrease in the TAFPS resistance,triggering the fire alarm system within 2 s.Additionally,benefiting from the force-sensitive behavior of the double helix layer and tightly wrapped pattern of the external heat-shrinkable tubular fabric,TAFPS demonstrated a high sensitivity of4.40 kPa^(-1)(0–5.81 k Pa)and good stability for 10000 s.Considering its excellent flame resistance,high sensitivity,and agreeable stability,the developed TAFPS can be integrated into fire suits to monitor the exercise training process and the external fire environment.This work offers a novel approach for fabricating all-fabric-based piezoresistive sensors in the future for fire prevention and fire alarms,with promising applications in fire protection,the Internet of Things,and smart apparel. | LI WeiBiao ZHANG Shuai MA ShuQi WANG JiaCheng WANG Huan YANG QiRong SONG YongTao ZHU Jie | 2024 | Science China(Technological Sciences)2024，67，4： | 0 |
| 11 | Pyridine terminated polyurethane dendrimer/chlorinated butyl rubber nanocomposites with excellent mechanical and damping properties显示文摘Due to the special viscoelastic property, traditional rubber with high performance has been widely used in human life and production. However, it is challenging to improve the damping property without sacrificing the extensibility. In this work, a novel type of second-generation polyurethane dendrimer terminated with pyridine(G2-Py) was synthesized by using thiolactone chemistry and subsequently complexed with Zn ions. The structure and morphology of G2-Py were characterized. G2-Py-Zn2+was then mixed with chlorinated butyl rubber(CIIR) by a two-roll mill. A series of CIIR/G2-Py-Zn2+elastomers were obtained through vulcanization. CIIR/G2-Py-Zn2+elastomers could achieve high stretchability(a strain of ~1035%), high mechanical strength(a tensile stress of 7.64 MPa). This was benefitted from the friction between G2-Py and CIIR as well as variety of non-covalent bonds provided by G2-Py-Zn2+,which can dissipate energy to further improve the strength and extensibility. The coordination of Zn2+-pyridine was confirmed by Fourier transform infrared spectroscopy, stress relaxation and cycle tensile test. To further investigate the morphology and damping properties of the elastomers, scanning electron microscopy and dynamic mechanical analysis were performed. CIIR-5 showed the best damping performance with higher tan δ_(max) and wider effective damping temperatures. Therefore, this dendrimer modification technology provides wider applications for CIIR elastomers in daily life. | Jiacheng Chen Jincheng Wang Shuhong Li Kailing Xiang Shiqiang Song | 2023 | Chinese Journal of Chemical Engineering2023，53，1： | 0 |
| 12 | On Dual-Mode Driving Control Method for a Novel Unmanned Tractor With High Safety and Reliability显示文摘Due to the non-standardization and complexity of the farmland environment,it is always a huge challenge for tractors to achieve fully autonomy(work at Self-driving mode)all the time in agricultural industry.Whereas,when tractors work in the Tele-driving(or Remote driving)mode,the operators are prone to fatigue because they need to concentrate for long periods of time.In response to these,a dual-mode control strategy was proposed to integrate the advantages of both approaches,i.e.,by combing Self-driving at most of the time with Tele-driving under special(complex and hazardous)conditions through switching control method.First,the state switcher was proposed,which is used for smooth switching the driving modes according to different working states of a tractor.Then,the state switching control law and the corresponding subsystem tracking controllers were designed.Finally,the effectiveness and superiority of the dualmode control method were evaluated via actual experimental testing of a tractor whose results show that the proposed control method can switch smoothly,stably,and efficiently between the two driving modes automatically.The average control accuracy has been improved by 20%and 15%respectively,compared to the conventional Tele-driving control and Self-driving control with low-precision navigation.In conclusion,the proposed dualmode control method can not only satisfy the operation in the complex and changeable farmland environment,but also free drivers from high-intensity and fatiguing work.This provides a perfect application solution and theoretical support for the intelligentization of unmanned farm agricultural machinery with high safety and reliability. | Wei Lu Jiacheng Li Huanhuan Qin Lei Shu Aiguo Song | 2023 | IEEE/CAA Journal of Automatica Sinica2023，10，1： | 0 |
| 13 | Unprotected quadratic band crossing points and quantum anomalous Hall effect in FeB_(2) monolayer显示文摘Quadratic band crossing points(QBCPs)and quantum anomalous Hall effect(QAHE)have attracted the attention of both theoretical and experimental researchers in recent years.Based on first-principle calculations,we find that the FeB_(2) monolayer is a nonmagnetic semimetal with QBCPs at K.Through symmetry analysis and k·p invariant theory,we find that the QBCP is not protected by rotation symmetry and consists of two Dirac points with the same chirality(Berry phase of 2π).Once introducing Coulomb interactions,we find that there is a spontaneous-time-reversal-breaking instability of the spinful QBCPs,which gives rise to a C=2 QAH insulator with orbital moment ordering. | DongYu Wu YunPeng Huang Song Sun JiaCheng Gao ZhaoPeng Guo HongMing Weng Zhong Fang Kun Jiang ZhiJun Wang | 2022 | Science China(Physics,Mechanics & Astronomy)2022，65，5： | 0 |
| 14 | Analysis of wave shoaling and shore-breakers on a low tide terrace beach based on in-situ measurements at Xisha Bay on South China coast显示文摘Low tide terrace beach is a main beach type along South China coasts with strong tidal actions.How strong tides affect wave transformations on low tide terrace beach still remains unclear.In this study,in-situ measurements are conducted on the low terrace beach at Xisha Bay to provide quantitative descriptions of wave shoaling and shore-breaker phenomena under the tidal effects.It is found that wave breaking is unsaturated on the low tide terrace beach at Xisha Bay.Magnitudes of wave skewness and asymmetry increase as wave shoals and achieve the maximum value at the shore-breaker,and then decrease rapidly.Mean energy dissipation rates of shore-breakers are tide-modulated since the bottom slope changes at the shoreward boundary of wave propagation in a tidal cycle.The remaining wave energy flux at the initialization of the shore-breaker is 1%–12%of offshore wave energy flux,and the energy flux ratio decreases with increasing offshore wave heights.Wave attenuation at shore-breakers can be estimated directly from offshore wave conditions based on findings in this study,favoring designs of seawalls or beach nourishment projects.Field datasets on wave transformations can also be used for verifications of wave numerical models. | Yuan Li Chi Zhang Hongshuai Qi Jiacheng Song Weiqi Dai Shanhang Chi Jian Shi Dake Chen | 2023 | Acta Oceanologica Sinica2023，42，7： | 0 |
| 15 | Bifunctional Two-Dimensional Nanocomposite with Electromagnetic Wave Absorption and Anti-bacterial Performance显示文摘In current electronic information era,the complex application circumstance of 5G devices pursues the exploration of multi-functional electromagnetic wave(EMW)absorbent materials and it has become the crucial focus in industrial development.A two-dimensional(2D)graphite nanosheet decorated by nickel nanocapsules(2D graphite/Ni@C nanocomposite)was fabricated to possess the EMW absorption and the Escherichia coli(E.coli)anti-bacterial performance simultaneously.By adjusting the filling ratio and injecting nitrogen doping,the value of minimum reflection loss is−36.08 dB and the effective absorption bandwidth reaches to 5.12 GHz(from 11.4 to 16.52 GHz)with the mass ratio of 30 wt%and the absorber thickness of 2 mm.This 2D nanocomposite simultaneously gets an excellent anti-bacterial function expressing an E.coli anti-bacterial rate of 92%during 24 h which is significantly correlated to the interaction between the nanostructure of the 2D nanographite and the nickel ion released from Ni@C nanocapsules.This work provides a new approach to develop a promising 2D anti-bacterial EMW absorber. | Jiacheng Shen Xinrui Zhang Chunguang Yang Zixuan Lei Shuaizhen Li Lin Ma Dianyu Geng Song Ma Wei Liu Zhidong Zhang | 2023 | Acta Metallurgica Sinica(English Letters)2023，36，9： | 0 |
| 16 | Targeting a cryptic allosteric site of SIRT6 with small-molecule inhibitors that inhibit the migration of pancreatic cancer cells显示文摘SIRT6 belongs to the conserved NAD^(+)-dependent deacetylase superfamily and mediates multiple biological and pathological processes.Targeting SIRT6 by allosteric modulators represents a novel direction for therapeutics,which can overcome the selectivity problem caused by the structural similarity of orthosteric sites among deacetylases.Here,developing a reversed allosteric strategy Allo Reverse,we identified a cryptic allosteric site,Pocket Z,which was only induced by the bi-directional allosteric signal triggered upon orthosteric binding of NAD^(+).Based on Pocket Z,we discovered an SIRT6 allosteric inhibitor named JYQ-42.JYQ-42 selectively targets SIRT6 among other histone deacetylases and effectively inhibits SIRT6 deacetylation,with an IC50 of 2.33μmol/L.JYQ-42 significantly suppresses SIRT6-mediated cancer cell migration and pro-inflammatory cytokine production.JYQ-42,to our knowledge,is the most potent and selective allosteric SIRT6 inhibitor.This study provides a novel strategy for allosteric drug design and will help in the challenging development of therapeutic agents that can selectively bind SIRT6. | Qiufen Zhang Yingyi Chen Duan Ni Zhimin Huang Jiacheng Wei Li Feng Jun-Cheng Su Yingqing Wei Shaobo Ning Xiuyan Yang Mingzhu Zhao Yuran Qiu Kun Song Zhengtian Yu Jianrong Xu Xinyi Li Houwen Lin Shaoyong Lu Jian Zhang | 2022 | Acta Pharmaceutica Sinica B2022，12，2： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员