|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | The wonders of BMP9:From mesenchymal stem cell differentiation,angiogenesis,neurogenesis,tumorigenesis,and metabolism to regenerative medicine显示文摘Although bone morphogenetic proteins(BMPs)initially showed effective induction of ectopic bone growth in muscle,it has since been determined that these proteins,as members of the TGF-b superfamily,play a diverse and critical array of biological roles.These roles include regulating skeletal and bone formation,angiogenesis,and development and homeostasis of multiple organ systems.Disruptions of the members of the TGF-b/BMP superfamily result in severe skeletal and extra-skeletal irregularities,suggesting high therapeutic potential from understanding this family of BMP proteins.Although it was once one of the least characterized BMPs,BMP9 has revealed itself to have the highest osteogenic potential across numerous experiments both in vitro and in vivo,with recent studies suggesting that the exceptional potency of BMP9 may result from unique signaling pathways that differentiate it from other BMPs.The effectiveness of BMP9 in inducing bone formation was recently revealed in promising experiments that demonstrated efficacy in the repair of critical sized cranial defects as well as compatibility with bone-inducing bio-implants,revealing the great translational promise of BMP9.Furthermore,emerging evidence indicates that,besides its osteogenic activity,BMP9 exerts a broad range of biological functions,including stem cell differentiation,angiogenesis,neurogenesis,tumorigenesis,and metabolism.This review aims to summarize our current understanding of BMP9 across biology and the body. | Sami Mostafa Mikhail Pakvasa Elam Coalson Allen Zhu Alex Alverdy Hector Castillo Jiaming Fan Alex Li Yixiao Feng Di Wu Elliott Bishop Scott Du Mia Spezia Alissa Li Ofir Hagag Alison Deng Winny Liu Mingyang Li Sherwin S·Ho Aravind Athiviraham Michael J·Lee Jennifer Moriatis Wolf Guillermo A·Ameer Hue H·Luu Rex C·Haydon Jason Strelzow Kelly Hynes Tong-Chuan He Russell R·Reid | 2019 | Genes & Diseases2019，6，3： | 15 |
| 2 | Recovery of neodymium,dysprosium,and cobalt from NdFeB magnet leachate using an unsymmetrical dialkylphosphinic acid extractant,INET-3显示文摘Rare earths (REs) and Co are critical strategic resources.Their recovery is crucial for ensuring that their supplies are adequate and for reducing environmental pollution.End-of-life NdFeB magnets are important secondary RE sources.The separation of Dy,Nd,and Co from NdFeB leachate using a relatively new extractant (2,3-dimethylbutyl)(2,4,4’-trimethylpentyl)phosphinic acid (INET-3),was investigated in this study.The separation parameters,such as equilibrium pH,phase ratio,INET-3 concentration,and number of counter-current extraction stages,were optimised.The results show that INET-3 can separate Dy,Nd,and Co efficiently.For the preferential extraction of Dy from synthetic iron-free NdFeB leachate,the optimum equilibrium pH is 2.60.Under this condition,separation of Dy from the leachate requires four counter-current extraction stages at A/O (volume ratio of aqueous to organic)=1:2.This is demonstrated by a simulated four-stage counter-current extraction process.At equilibrium pH=2.52and A/O=1:2,98%of Dy is recovered with 95%purity.As to the subsequent separation of Nd from the leachate,nearly 100%is recovered with 99%purity through a simulated three-stage counter-current extraction process at equilibrium pH=5.33 and A/O=1:1.Approximately 95%of Co remains in the raffinate with 99.98%purity. | Zhengyu Liu a Jiaming Wu a Xinyu Liu Wen Wanga Ziwei Li Ruijing Xu Yue Ding Junlian Wang | 2020 | Journal of Rare Earths2020，38，10： | 3 |
| 3 | Experimental investigation on a two-part underwater towed system显示文摘 | Wu Jiaming Chwang A T | 2001 | Ocean Engineering2001，28，6： | 1 |
| 4 | Timing, duration, and transitions of the last interglacial Asian monsoon 显示文摘 | Yuan Daoxian Cheng Hai Edwards R L Dykoski C A Kelly M J Zhang Meiliang Qing Jiaming Lin Yushi Wang Yongjin Wu Jiangyin Dorale J A An Zhisheng Cai Yanjun | 2004 | Science2004，304，5670： | 1 |
| 5 | A hydrodynamic model of a two - part underwater towed system 显示文摘 | Wu Jiaming A T Chwang | 2000 | Ocean Engineering2000，27，5： | 1 |
| 6 | A hydrodynamic model of a two-part underwater towed system显示文摘 | Wu Jiaming Chwang A T | 2000 | Ocean Engineering2000，27，5： | 1 |
| 7 | Investigation on a two-part underwater maneuverable towed system显示文摘 | Wu Jiaming Chwang A T | 2001 | Ocean Engineering2001，28，8： | 1 |
| 8 | Timing,duration,and transitions of the last interglacial Asian monsoon显示文摘 | Yuan Daoxian Cheng Hai Edwards R L Dykoski C A Kelly M J Zhang Meiliang Qing Jiaming Lin Yushi Wang Yongjin Wu Jiangying Dorale J A An Zhisheng Cai Yanjun | | 0，，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员