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| 1 | Soil salinization research in China: Advances and prospects显示文摘与气候变化的进展引起的环境恶化,土壤 salinization 是一个严重、成长的全球问题。当前,大约 7% 世界陆地表面被 salinization 威胁。中国是其土壤被这个问题严重地影响的一个国家,它由于它的广泛的区域,并且宽分发形成严肃的威胁到地区性的农业开发。在这评论,我们在过去的 70 年在中国为土壤 salinization 研究总结框架,估计存在的软弱在两个研究国内、国际的上下文,加亮趋势并且给关于在过去的 30 年的盐的土壤的全球研究的调查结果调音,并且为关于盐的土壤的未来研究建议六个主要领域和方向。 | LI Jianguo PU Lijie HAN Mingfang ZHU Ming ZHANG Runsen XIANG Yangzhou | 2014 | Journal of Geographical Sciences2014，24，5： | 90 |
| 2 | Suppression of Jasmonic Acid-Mediated Defense by Viral-Inducible MicroRNA319 Facilitates Virus Infection in Rice显示文摘MicroRNAs (miRNAs ) 是植物开发和主人病毒相互作用的枢轴的调节的人。然而,角色和涉及病毒的感染和主人危险性的特定的 miRNAs 的行动模式仍然保持大部分不清楚。在这研究,我们给那瑞斯看引起 miR319 的增加的累积,但是减少的破旧绝技病毒(RRSV ) 感染调整 miR319 的 TCP (TEOSINTE BRANCHED/CYCLOIDEA/PCF ) 的表示基因,特别 TCP21,在米饭植物。转基因的米饭植物 overexpressing miR319 或 downregulating TCP21 展出了像疾病的显型并且与野类型的植物比较显示出显著地更高的危险性到 RRSV。相反,仅仅温和的疾病症状在感染 RRSV 的线 overexpressing TCP21 并且特别在转基因的植物 overexpressing 被观察 miR319 抵抗的 TCP21。miR319 的 RRSV 感染和 overexpression 在米饭与 JA 生合成和信号相关的基因的 downregulated 表示一起引起了减少的内长的 jasmonic 酸(JA ) 层次。然而,有甲基 jasmonate 的米饭植物的治疗减轻了 RRSV 引起并且减少了病毒累积的疾病症状。一起拿,我们的结果建议由在米饭的 RRSV 感染的 miR319 的正式就职压制调停 JA 的防卫便于病毒感染和症状开发。 | Chao Zhang Zuomei Ding Kangcheng Wu Liang Yang Yang Li Zhen Yang Shan Shi Xiaojuan Liu Shanshan Zhao Zhirui Yang Yu Wang Luping Zheng Juan Wei Zhenguo Du Aihong Zhang Hongqin Miao Yi Li Zujian Wu Jianguo Wu | 2016 | Molecular Plant2016，9，9： | 27 |
| 3 | Effect of Lichong decoction on expression of Bcl-2 and Bcl-2-associated X protein mRNAs in hysteromyoma model rat显示文摘OBJECTIVE:To study on effects of Lichong decoction on expression of apoptosis-controlling genes,Bcl-2 and Bcl-2-associated X protein(Bax) mRNAs in hysteromyoma tissue of the hysteromyoma model rat.METHODS:Fifty Wistar female rats were randomly divided into a normal group,a model group,a Lichong decoction group,a Guizifuling capsule group and a Mifepristone group.The hysteromyoma rat model was established by intraperitoneal injection of exogenous estrin and progestogens.Pathological examination of uterine tissue,uterine coefficient and uterine transverse diameter were made under optic microscope and expressions of Bcl-2 and Bax mRNAs in uterine tissue in the groups were detected with real-time fluorescent quantitative polymerase chain reaction(PCR) technique.RESULTS:After treatment,under microscope it was found that in the Lichong decoction group myometrium thinned,muscle fiber slightly overgrowth or long and thin,regular arrangement,inserting phenomenon of inner circular muscle and external longitudinal muscle was occasionally or not seen in the Lichong decoction group.The uterine coefficient and the uterine transverse diameter significantly decreased(P<0.01),and Bcl-2 mRNA expression significantly decreased(P<0.01) and Bax mRNA expression significantly increased in hysteromyoma tissue(P<0.01) in the Lichong decoction group as compared with the model group.CONCLUSION:Therapeutic effects of Lichong decoction on hysteromyoma is related with decrease of Bcl-2 mRNA expression and increase of Bax mRNA expression. | Donghua Li Xin Xu Ruiya Qian Jianguo Geng Yan Zhang Xiaolei Xie Yasong Wang Xiaoli Zou | 2013 | Journal of Traditional Chinese Medicine2013，33，2： | 24 |
| 4 | Behavior of composite rigid frame bridge under bi-directional seismic excitations显示文摘Pushover analysis and time history analysis are conducted to explore the bi-directional seismic behavior of composite steel-concrete rigid frame bridge,which is composed of RC piers and steel-concrete composite girders.Both longitudinal and transverse directions excitations are investigated using OpenSees.Firstly,the applicability of pushover analysis based on the fundamental mode is discussed.Secondly,an improved pushover analysis method considering the contribution of higher modes is proposed,and the applicability on composite rigid frame bridges under bi-directional earthquake is verified.Based on this method,an approach to predict the displacement responses of composite rigid frame bridge under random bi-directional seismic excitations by revising the elasto-plastic demand curve is also proposed.It is observed that the developed method yield a good estimate on the responses of composite rigid frame bridges under bi-directional seismic excitations. | Xiaogang Liu Jiansheng Fan Jianguo Nie Guo Li | 2014 | Journal of Traffic and Transportation Engineering(English Edition)2014，1，1： | 22 |
| 5 | Identification of long-range transport pathways and potential sources of PM2.5 and PM10 in Beijing from 2014 to 2015显示文摘Trajectory clustering, potential source contribution function(PSCF) and concentration-weighted trajectory(CWT) methods were applied to investigate the transport pathways and identify potential sources of PM_(2.5)and PM_(10) in different seasons from June 2014 to May 2015 in Beijing.The cluster analyses showed that Beijing was affected by trajectories from the south and southeast in summer and autumn. In winter and spring, Beijing was not only affected by the trajectories from the south and southeast, but was also affected by trajectories from the north and northwest. In addition, the analyses of the pressure profile of backward trajectories showed that backward trajectories, which have important influence on Beijing, were mainly distributed above 970 h Pa in summer and autumn and below 950 h Pa in spring and winter. This indicates that PM_(2.5)and PM_(10) were strongly affected by the near surface air masses in summer and autumn and by high altitude air masses in winter and spring. Results of PSCF and CWT analyses showed that the largest potential source areas were identified in spring, followed by winter and autumn,then summer. In addition, potential source regions of PM_(10) were similar to those of PM_(2.5). There were a clear seasonal and spatial variation of the potential source areas of Beijing and the airflow in the horizontal and vertical directions. Therefore, more effective regional emission reduction measures in Beijing's surrounding provinces should be implemented to reduce emissions of regional sources in different seasons. | Deping Li Jianguo Liu Jiaoshi Zhang Huaqiao Gui Peng Du Tongzhu Yu Jie Wang Yihuai Lu Wenqing Liu Yin Cheng | 2017 | Journal of Environmental Sciences2017，29，6： | 22 |
| 6 | An alternative therapy for drug-resistant epilepsy: transcutaneous auricular vagus nerve stimulation显示文摘 | Rong Peijing Liu Aihua Zhang Jianguo Wang Yuping Yang Anchao Li Liang Ben Hui Li Liping Liu Rupeng He Wei Liu Huanguang Huang Feng Li Xia Wu Peng Zhu Bing | 2014 | Chinese Medical Journal2014，，2： | 20 |
| 7 | Cold adaptation in pigs depends on UCP3 in beige adipocytes显示文摘 | Jun Lin Chunwei Cao Cong Tao Rongcai Ye Meng Dong Qiantao Zheng Chao Wang Xiaoxiao Jiang Guosong Qin Changguo Yan Kui Li John R. Speakman Yanfang Wang Wanzhu Jin Jianguo Zhao | 2017 | Journal of Molecular Cell Biology2017，9，5： | 20 |
| 8 | Genome Analysis of the Ancient Tracheophyte Selaginella tama#scina Reveals Evolutionary Features Relevant to the Acquisition of Desiccation Tolerance显示文摘 | Zhichao Xu Tianyi Xin Dorothea Bartels Ying Li Wei Gu Hui Yao Sai Liu Haoying Yu Xiangdong Pu Jianguo Zhou Jiang Xu Caicai xi Hetian Lei Jingyuan song Shilin Chen | 2018 | Molecular Plant2018，11，7： | 20 |
| 9 | Thermal cracking of aviation kerosene for scramjet applications显示文摘Thermal cracking of China No.3 aviation kerosene was studied experimentally and analytically under supercritical conditions relevant to regenerative cooling system for Mach-6 scramjet applications. A two-stage heated tube system with cracked products collection/analysis was used and it can achieve a fuel temperature range of 700―1100 K,a pressure range of 3.5―4.5 MPa and a residence time of ap-proximately 0.5―1.3 s. Compositions of the cracked gaseous products and mass flow rate of the kerosene flow at varied temperatures and pressures were obtained experimentally. A one-step lumped model was developed with the cracked mixtures grouped into three categories:unreacted kerosene,gaseous products and residuals including liquid products and carbon deposits. Based on the model,fuel conversion on the mass basis,the reaction rate and the residence time were estimated as functions of temperature. Meanwhile,a sonic nozzle was used for the control of the mass flow rate of the cracked kerosene,and correlation of the mass flow rate gives a good agreement with the measurements. | ZHONG FengQuan FAN XueJun YU Gong LI JianGuo | 2009 | Science China(Technological Sciences)2009，52，9： | 18 |
| 10 | A miniature liquid helium temperature JT cryocooler for space application显示文摘Along with the development of space science and technology,miniature liquid helium temperature long life cryocooler is a focus subject in cryogenic study.Since it is the precondition of space detection researches,institutions of space in many countries do the research on it.In this article,we designed a compound cooling system.A three-stage high frequency thermal coupled pulse tube cryocooler was used to precool a Joule-Thomson(JT)cryocooler.This system has no moving parts at low temperatures and is hence suitable for space operation.Liquid helium temperature was successfully achieved in both open loop and closed cycle experiments.In the closed cycle experiment,when 473 W electric power was inputted,the cooling system reached a no-load temperature of 4.4 K,and a cooling capacity of 11.6 mW was provided at 4.54 K.It is the first miniature liquid helium temperature JT cryocooler in China and the research achievement paves a way for the space application of ultra-long wave infrared detection and THz technologies. | QUAN Jia ZHOU ZhenJun LIU YanJie LI JianGuo MA YueXue LIANG JingTao | 2014 | Science China(Technological Sciences)2014，57，11： | 16 |
| 11 | De novo mutation in ATP6V1B2 impairs lysosome acidification and causes dominant deafness-onychodystrophy syndrome显示文摘 | Yongyi Yuan Jianguo Zhang Qing Chang Jin Zeng Feng Xin Jianjun Wang Qingyan Zhu Jing Wu Jingqiao Lu Weiwei Guo Xukun Yan Hui Jiang Binfei Zhou Qi Li Xue Gao Huijun Yuan Shiming Yang Dongyi Han Zixu Mao Ping Chen Xi Lin Pu Dai | 2014 | Cell Research2014，24，11： | 13 |
| 12 | Guiding-controlling technology of coal seam hydraulic fracturing fractures extension显示文摘Aiming at the uncontrollable problem of extension direction of coal seam hydraulic fracturing,this study analyzed the course of fractures variation around the boreholes in process of hydraulic fracturing,and carried out the numerical simulations to investigate the effect of artificial predetermined fractures on stress distribution around fractured holes.The simulation results show that partial coal mass occurs relatively strong shear failure and forms weak surfaces,and then fractures extended along the desired direction while predetermined fractures changed stress distribution.Directional fracturing makes the fractures link up and the pressure on coal mass is relieved within fractured regions.Combining deep hole controlling blasting with hydraulic fracturing was proposed to realize the extension guiding-controlling technology of coal seam fractures.Industrial experiments prove that this technology can avoid local stress concentration and dramatically widen the pressure relief scope of deep hole controlling blasting.The permeability of fractured coal seam increased significantly,and gas extraction was greatly improved.Besides,regional pressure relief and permeability increase was achieved in this study. | Zhai Cheng Li Min Sun Chen Zhang Jianguo Yang Wei Li Quangui | 2012 | International Journal of Mining Science and Technology2012，22，6： | 12 |
| 13 | Clinical characteristics of human infection with a novel avian-origin influenza A(H10N8) virus显示文摘 | Zhang Wei Wan Jianguo Qian Kejian Liu Xiaoqing Xiao Zuke Sun Jian Zeng Zhenguo Wang Qi Zhang Jinxiang Jiang Guanghui Nie Cheng Jiang Rong Ding Chengzhi Li Ran Horby Peter Gao Zhancheng | 2014 | Chinese Medical Journal2014，，18： | 12 |
| 14 | Lichong decoction reduces Matrix Metalloproteinases-2 expression but increases Tissue Inhibitors of Matrix Metalloproteinases-2 ex-pression in a rat model of uterine leiomyoma显示文摘OBJECTIVE:To study the effect of Lichong decoction(LD) on expression of matrix metalloproteinase-2(MMP-2) and metalloproteinase-2(TIMP-2) in a rat model of uterine leiomyoma(UL).METHODS:UL was induced in rats using exogenous estrogen and progesterone.LD was administered(p.o.) for 4 weeks,and mifepristone(RU-486)used as a control.To observe the effect of LD on the uterine coefficient and uterine transverse diameter,a radioimmunoassay method was used to detect serum levels of sex hormones.Light microscopic analyses of pathologic changes in the tissues of UL rats were evaluated.Expression of the proteins of matrix metalloproteinases(MMPs) and tissue inhibitors of metalloproteinases(TIMPs) in uterine tissues was assessed by immunohistochemical staining and western blotting.RESULTS:A UL model in rats was established successfully.LD reduced uterine weight,uterine coefficient,and uterine transverse diameter compared with untreated controls.LD reduced levels of estradiol,progesterone,follicle-stimulating hormone,and luteinizing hormone in our UL models.LD improved the pathologic condition of uterine muscle.Expression of MMP-2 protein decreased to varying extents in LD-treated groups,but TIMP-2 levels were enhanced.LD appears to reduce MMP-2 expression and increase TIMP-2 expression in UL tissue.CONCLUSION:These data suggest that the mechanism of action of LD on ULs may involve reduction of MMP-2 expression and increase in TIMP-2 expression in rats. | Wang Yasong Li Donghua Xu Xin Qian Ruiya Zhang Yalan Huang Yuhua Geng Jianguo Zou Xiaoli Han Hon-gjuan Zhang Wufang | 2016 | Journal of Traditional Chinese Medicine2016，36，4： | 12 |
| 15 | Structure Styles of Mesozoic-Cenozoic U-bearing Rock Series in Northern China显示文摘In Northern China,sandstone-type uranium(U) deposits are mostly developed in MesozoicCenozoic basins. These U deposits are usually hosted in unvarying horizons within the basins and exhibit typical U-forming sedimentary associations,which is referred to as U-bearing rock series. This study describes the structural features of U-bearing rock series within the main Mesozoic-Cenozoic Uproducing continental basins in Kazakhstan,Uzbekistan,and Russia in the western segment of the Central Asian Metallogenic Belt(CAMB),and Northern China in the eastern segment of the CAMB. We analyze the basic structural conditions and sedimentary environments of U-bearing rock series in Northern China and classify their structural styles in typical basins into river valley,basin margin,and intrabasin uplift margin types. The intrabasin uplift margin structural style proposed in this study can be used to indicate directions for the exploration of sandstone-type U deposits hosted in the center of a basin. At the same time,the study of structural style provides a new idea for exploring sandstone-type U deposits in Mesozoic-Cenozoic basins and it is of great significance to prospecting of sandstone-type uranium deposits. | JIN Ruoshi MIAO Peisen SIMA Xianzhang LI Jianguo ZHAO Hualei ZHAO Fengqing FEN Xiaoxi CHEN Yin CHEN Lulu ZHAO Lijun ZHU Qiang | 2016 | Acta Geologica Sinica(English Edition)2016，90，6： | 12 |
| 16 | Esophageal cancer:Epidemiology,risk factors and screening显示文摘More than 600,000 people are diagnosed with esophageal cancer(EC)every year globally,and the five-year survival rate of EC is less than 20%.Two common histological subtypes of EC,esophageal squamous cell carcinoma(ESCC)and esophageal adenocarcinoma(EAC),have great geographical variations in incidence rates.About half of the world’s EC was diagnosed in China and a majority of which belong to ESCC.Globally,the overall incidence rate of EC is decreasing.In some high-risk Asian regions,such as China,the incidence rate of ESCC has generally declined,potentially due to economic growth and improvement of diet habits.In some European high-income countries and the United States,the decline is mainly attributed to the decrease in smoking and drinking.The risk factors of EC are not well understood,and the importance of environmental and genetic factors in the pathogenesis is also unclear.The incidence and mortality of advanced EC can be reduced through early diagnosis and screening.White light endoscopy is still the gold standard in the current screening technology.This article reviews the epidemiology,risk factors,and screening strategies of EC in recent years to help researchers determine the most effective management strategies to reduce the risk of EC. | Jiang Li Jianguo Xu Yadi Zheng Ya Gao Siyi He He Li Kaiyong Zou Ni Li Jinhui Tian Wanqing Chen Jie He | 2021 | Chinese Journal of Cancer Research2021，33，5： | 12 |
| 17 | The First Discovery of a Large Sandstone-type Uranium Deposit in Aeolian Depositional Environment显示文摘The exploration depth of sandstone-type uranium deposits worldwide is mostly less than 700 m,and most of them occur in strata of fluvial facies(Adams et al.,1981;Jin et al.,2016;Hou et al.,2017).Only a few small uranium deposits have been reported in aeolian depositional environments(Isachsen et al.,1955;Li et al.,2001).In the Pcngyang Jingchuan region of the southwestern Ordos Basin,uranium ore bodies with large thickness and high grade in the aeolian sandstone of the Luohe Formation were newly found at depths from 700 to 1500 m,which have laid the foundation for increasing the uranium resources significantly in the Ordos Basin. | MIAO Peisen JIN Ruoshi LI Jianguo ZHAO Hualei CHEN Lulu CHEN Yin SI Qinghong | 2020 | Acta Geologica Sinica(English Edition)2020，94，2： | 12 |
| 18 | Effect of Lichong Decoction on expression of IGF-I and proliferating cell nuclear antigen mRNA in rat model of uterine leiomyoma显示文摘OBJECTIVE:To study the effect of Lichong Decoction(Lichong Decoction for strengthening anti-pathogenic Qi and eliminating blood stasis) on the expression of insulin-like growth factor-I(IGF-I) and proliferating cell nuclear antigen(PCNA) mRNA in a rat model of uterine leiomyoma.METHODS:Fifty female Wistar rats were randomized into a normal control group,model group,Lichong Decoction group,Guizhifuling Capsule(Capsule containing Cassia Twig and Poria) group,and Mifepristone group.The uterine leiomyoma model was established by peritoneal injections of exogenous estrogen and progesterone hormone.The ultrastructural changes in cells of rat uterine tissues were observed with transmission electron microscopy,and the expression of IGF-I and PCNA mRNA was detected by real-time fluorescent quantitative PCR.RESULTS:Following treatment,cells in the Lichong Decoction group appeared to be arranged normally,the cellular morphology were almost in a normal state,hyperplasia and hypertrophy of the chondriosome was reduced,collagen fibers were arranged in a regular manner,without obvious hyperplasia,and the expression of IGF-I and PCNA mRNA was significantly decreased compared with the model group(P<0.01).CONCLUSIONS:The effect of Lichong Decoction on uterine leiomyoma is related to its function in reducing the expression of IGF-I and PCNA mRNA. | Donghua Li Yalan Zhang Hongjuan Han Jianguo Geng Xiaolei Xie Jiubo Zheng Yasong Wang Xiaoli Zou | 2012 | Journal of Traditional Chinese Medicine2012，32，4： | 11 |
| 19 | First observation of tropospheric nitrogen dioxide from the Environmental Trace Gases Monitoring Instrument onboard the GaoFen-5 satellite显示文摘The Environmental Trace Gases Monitoring Instrument(EMI)is the first Chinese satellite-borne UV–Vis spectrometer aiming to measure the distribution of atmospheric trace gases on a global scale.The EMI instrument onboard the GaoFen-5 satellite was launched on 9 May 2018.In this paper,we present the tropospheric nitrogen dioxide(NO2)vertical column density(VCD)retrieval algorithm dedicated to EMI measurement.We report the first successful retrieval of tropospheric NO_(2) VCD from the EMI instrument.Our retrieval improved the original EMI NO_(2) prototype algorithm by modifying the settings of the spectral fit and air mass factor calculations to account for the on-orbit instrumental performance changes.The retrieved EMI NO_(2) VCDs generally show good spatiotemporal agreement with the satellite-borne Ozone Monitoring Instrument and TROPOspheric Monitoring Instrument(correlation coefficient R of ~0.9,bias<50%).A comparison with ground-based MAX-DOAS(Multi-Axis Differential Optical Absorption Spectroscopy)observations also shows good correlation with an R of 0.82.The results indicate that the EMI NO_(2) retrieval algorithm derives reliable and precise results,and this algorithm can feasibly produce stable operational products that can contribute to global air pollution monitoring. | Chengxin Zhang Cheng Liu Ka Lok Chan Qihou Hu Haoran Liu Bo Li Chengzhi Xing Wei Tan Haijin Zhou Fuqi Si Jianguo Liu | 2020 | Light(Science & Applications)2020，9，1： | 11 |
| 20 | Deacetylation of TFEB promotes fibrillar Aβ degradation by upregulating lysosomal biogenesis in microglia显示文摘Microglia 玩在由降级的 A 的清理的一个枢轴的角色他们在 lysosomes,在 Alzheimers 疾病(广告) 阻止淀粉的匾致病。最近的证据建议那个 lysosomal 机能障碍导致有毒的蛋白质总数的不够的消除。我们测试了是否与抄写因素 EB (TFEB ) 提高 lysosomal 功能,必要管理者 modulating lysosomal 小径,将在 microglia 支持一个清理。这里,我们证明 TFEB 的那 microglial 表情便于降级和还原剂扔了的纤丝状的 A (fA ) 淀粉的匾,它被 TFEB 的 deacetylation 进一步提高。用集体 spectrometry 分析,我们第一证实了是的 acetylation 一以前 TFEB 的 unreported 修正并且发现那 SIRT1 直接交往了与并且在离氨酸残余 116 点的 deacetylated TFEB。随后,当 TFEB 被击倒时, SIRT1 overexpression 由 TFEB 下游的目标的 upregulating transcriptional 层次提高了 lysosomal 功能和 fA 降级,它能被禁止。而且,在在 microglia 变异的 K116R 的 deacetylated TFEB 的 overexpression 由刺激 lysosomal 生物的续生说加速了细胞内部的 fA 降级并且极大地在 APP/PS1 转基因的老鼠的大脑片减少了扔的淀粉的匾。我们的调查结果表明 TFEB 的 deacetylation 能调整 lysosomal 生物的续生说和 fA 降级,为 attenuating 使 TFEB 的 microglial 激活成为可能的策略在广告的淀粉的匾免职。 | Jintao Bao Liangjun Zheng Qi Zhang Xinya Li Xuefei Zhang Zeyang Li Xue Bai Zhong Zhang Wei Huo Xuyang Zhao Shujiang Shang Qingsong Wang Chen Zhang Jianguo Ji | 2016 | Protein & Cell2016，7，6： | 10 |
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