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5篇 您的检索式:作者名="Jianchen Fang"
    题名 作者 年代 出处 被引量
1Diabolical points in coupled active cavities with quantum emitters显示文摘In single microdisks,embedded active emitters intrinsically affect the cavity modes of the microdisks,resulting in trivial symmetric backscattering and low controllability.Here we demonstrate macroscopic control of the backscattering direction by optimizing the cavity size.The signature of the positive and negative backscattering directions in each single microdisk is confirmed with two strongly coupled microdisks.Furthermore,diabolical points are achieved at the resonance of the two microdisks,which agrees well with theoretical calculations considering the backscattering directions.Diabolical points in active optical structures pave the way for an implementation of quantum information processing with geometric phase in quantum photonic networks.Jingnan Yang Chenjiang Qian Xin Xie Kai Peng Shiyao Wu Feilong Song Sibai Sun Jianchen Dang Yang Yu Shushu Shi Jiongji He Matthew JSteer Iain GThayne Bei-Bei Li Fang Bo Yun-Feng Xiao Zhanchun Zuo Kuijuan Jin Changzhi Gu Xiulai Xu 2020Light(Science & Applications)2020,9,1:2
2A new structure forpermaiicnt-magnet-hiased axial hybird magnetic bearings 显示文摘Fang Jianchen Sun Jinji Xu Yanliang 2009IEEE Transactions on Magnetics2009,45,12:1
3Antibody-activated trans-endothelial delivery of mesoporous organosilica nanomedicine augments tumor extravasation and anti-cancer immunotherapy显示文摘Tumor vasculature constitutes a formidable hurdle for the efficient delivery of cancer nanomedicine into tumors.The leverage of passive pathway through inter-endothelial gaps in tumor blood vessels might account for limited extravasation of nanomedicine into tumor microenvironment(TME).Herein,Annexin A1 antibody-installed mesoporous organosilica nanoplatforms carrying immunotherapeutics of anti-PD-L1 antibody(aPD-L1)and Indoximod are developed to target at caveolar Annexin-A1 protein of luminal endothelial cells and to trigger the active trans-endothelial transcytosis of nanomedicine mediated by caveolae.Such strategy enables rapid nanomedicine extravasation across tumor endothelium and relatively extensive accumulation in tumor interstitium.aPD-L1 and Indoximod release from aPD/IND@MON-aANN in a reduction-responsive manner and synergistically facilitate the intratumoral infiltration of cytotoxic T lymphocytes and reverse the immunosuppressive TME,thus demonstrating substantial anti-tumor efficacy in subcutaneous 4T1 breast tumors and remarkable anti-metastatic capacity to extend the survival of 4T1 tumor metastasis model.Moreover,aPD/IND@MON-aANN nanomedicine also exhibits distinct superiority over the combination therapy of free drugs to potently attenuate the progression of urethane-induced orthotopic lung cancers.Collectively,aPD/IND@MON-aANN nanoplatforms with boosted delivery efficiency via antibody-activated trans-endothelial pathway and enhanced immunotherapeutic efficacy provides perspectives for the development of cancer nanomedicines.Tinglei Huang Shuang Li Jianchen Fang Fuli Li Shuiping Tu 2021Bioactive Materials2021,6,7:1
4Near net forming of metal-ceramic parts by plasma spraying显示文摘Zhao Ziyu Wang L Fang Jianchen 2005Key Engineering Materials2005,18,111:1
5A new structure for permanent-magnet-biased axial hybrid magnetic bearings 显示文摘FANG Jianchen SUN Jinji XU Yanliang 2009IEEE Transactions on Magnetics2009,45,2:1
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