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| 1 | Characterization and distribution of polycyclic aromatic hydrocarbon in sediments of Haihe River, Tianjin, China显示文摘在这学习沉积,样品从 Haihe 河 inTianjin 城市的 13 个地点被收集,中国,十六优先级多不的芳香的烃(哼)借助于 GC-MS.The 全部的集中在 USEPA wereanalyzed 列出了哼从 774.81~255371.91 ng/gdw ,并且二~四响哼在沉积 samples.Molecular 比率,如此的 asphenanthrene/anthracene , fluoranthene/pyrene 和 low-molecular-weight PAH/high-molecular-weightPAH 是主导的,被用来学习 pollutio | JIANG Bin ZHENG Hai-long HUANG Guo-qiang DING Hui LI Xin-gang SUO Hong-tu LI Rui | 2007 | Journal of Environmental Sciences2007，19，3： | 29 |
| 2 | Serum pepsinogen Ⅱ is a better diagnostic marker in gastric cancer显示文摘AIM:To investigate screening makers for gastric cancer,we assessed the association between gastric cancer and serum pepsinogens(PGs).METHODS:The subjects comprised 450 patients with gastric cancer,111 individuals with gastric atrophy,and 961 healthy controls.Serum anti-Helicobacter pylori(H.pylori) immunoglobulin G(IgG),PGⅠand PG Ⅱ were detected by enzyme-linked immunosorbent assay.Gastric atrophy and gastric cancer were diagnosed by endoscopy and histopathological examinations.Odds ratios and 95%CIs were calculated using multivariate logistic regression.RESULTS:Rates of H.pylori infection remained high in Northeastern China.Rates of H.pylori IgG positivity were greater in the gastric cancer and gastric atrophy groups compared to the control group(69.1% and 75.7% vs 49.7%,P < 0.001).Higher levels of PG Ⅱ(15.9 μg/L and 13.9 μg/L vs 11.5 μg/L,P < 0.001) and lower PGⅠ/PG Ⅱ ratio(5.4 and 4.6 vs 8.4,P < 0.001) were found in patients with gastric cancer or gastric atrophy compared to healthy controls,whereas no correlation was found between the plasma PGⅠconcentration and risk of gastric cancer(P = 0.537).In addition,multivariate logistic analysis indicated that H.pylori infection and atrophic gastritis were independent risk factors for gastric cancer.Lower plasma PGⅠ/PG Ⅱ ratio was associated with higher risks of atrophy and gastric cancer.Furthermore,plasma PG Ⅱ?level?significantly?correlated?with?H.pyloriinfected gastric cancer.CONCLUSION:Serum PG Ⅱ concentration and PG Ⅰ/PG Ⅱ ratio are potential biomarkers for H.pyloriinfected gastric disease.PG Ⅱ is independently associated with risk of gastric cancer. | Xue-Yuan Cao Zhi-Fang Jia Mei-Shan Jin Dong-Hui Cao Fei Kong Jian Suo Jing Jiang | 2012 | World Journal of Gastroenterology2012，18，48： | 27 |
| 3 | Evaluation of malignancy using Ki-67,p53,EGFR and COX-2 expressions in gastrointestinal stromal tumors显示文摘AIM:To investigate the role of expressions of Ki-67, p53,epidermal growth factor receptor(EGFR)and cyclooxygenase-2(COX-2)in gastrointestinal stromal tumor(GIST)grading and prognosis. METHODS:Tumor tissue was collected retrospectively from 96 patients with GIST.Antibodies against Ki-67, p53,EGFR and COX-2 were used for immunohistochemical staining.Tumor grading was designated according to a consensus system and the staining was quantified in 3 categories for each antibody in the statistical analysis. RESULTS:The Ki-67 expression in GISTs was significantly associated with the size of the tumors,mitotic rate and the risk of malignancy(x2=15.51,P=0.02; x2=22.27,P<0.001;x2=20.05;P<0.001).The p53 expression was also significantly correlated with mitotic rate and the risk of malignancy(x2=9.92,P= 0.04;x2=9.97;P=0.04).Over-expression of Ki-67 was strongly correlated with poor survival(x2=10.44, P=0.006),but no correlation was found between the expression of p53,EGFR or COX-2 and survival. Multivariate analysis further demonstrated that Ki-67 expression(relative risk=15.78,95%CI:4.25-59.37) could be used as an independent prognostic value for GIST patients.Adjuvant imatinib therapy could improve clinical outcomes in the patients with high risk and intermediate risk of recurrence after complete tumor resections(median survival time:52 mo vs 37 mo, x2=7.618,P=0.006). CONCLUSION:Our results indicated that the expression of Ki-67 could be used as an independent prognostic factor for GIST patients. | Jing Jiang Mei-Shan Jin Jian Suo Yin-Ping Wang Liang He Xue-Yuan Cao | 2012 | World Journal of Gastroenterology2012，18，20： | 13 |
| 4 | Artificial Neural Network to Predict Leaf Population Chlorophyll Content from Cotton Plant Images显示文摘Leaf population chlorophyll content in a population of crops,if obtained in a timely manner,served as a key indicator for growth management and diseases diagnosis.In this paper,a three-layer multilayer perceptron(MLP) artificial neural network(ANN) based prediction system was presented for predicting the leaf population chlorophyll content from the cotton plant images.As the training of this prediction system relied heavily on how well those leaf green pixels were separated from background noises in cotton plant images,a global thresholding algorithm and an omnidirectional scan noise filtering coupled with the hue histogram statistic method were designed for leaf green pixel extraction.With the obtained leaf green pixels,the system training was carried out by applying a back propagation algorithm.The proposed system was tested to predict the chlorophyll content from the cotton plant images.The results using the proposed system were in sound agreement with those obtained by the destructive method.The average prediction relative error for the chlorophyll density(μg cm-2) in the 17 testing images was 8.41%. | SUO Xing-mei JIANG Ying-tao YANG Mei LI Shao-kun WANG Ke-ru WANG Chong-tao | 2010 | Agricultural Sciences in China2010，9，1： | 11 |
| 5 | Clinical and molecular analysis of hereditary non-polyposis colorectal cancer in Chinese colorectal cancer patients显示文摘AIM:To analyze the frequency of hereditary non-polyposis colorectal cancer(HNPCC)in Chinese colorectal cancer(CRC)patients,and to discuss the value of microsatellite instability(MSI)and/or immunohistochemistry(IHC)for MSH2/MLH1 protein analysis as pre-screening tests in China.METHODS:The Amsterdam criteriaⅠandⅡ(clinical diagnosis)and/or germline hMLH1/hMSH2 mutations(genetic diagnosis)were used to classify HNPCC families.Genetic tests,including microsatellite instability,immunohistochemistry for MSH2/MLH1 proteins and hMSH2/hMLH1 genes,were performed in each proband.RESULTS:From July 2000 to June 2004,1988 patients with colorectal cancer were analysed and 114 CRC patients(5.7%)from 48 families were categorized as having HNPCC,including 76 from 26 families diagnosed clinically and 38 from the other 22 families diagnosed genetically.The sensitivity and specificity of high MSI and IHC for predicting mutations were 100% and 54%,and 79% and 77%,respectively.CONCLUSION:The frequency of HNPCC is approximately 10% among all Chinese CRC cases.The MSI and IHC detections for hMSH2/hMLH1 proteins are reliable pre-screening tests for hMLH1/hMSH2 germline mutations in families suspected of having HNPCC. | Jun Wang Mao-Hong Luo Zuo-Xing Zhang Pei-Da Zhang Xi-Li Jiang Dong-Wang Ma Rong-Zeng Suo Li-Zhong Zhao Qing-Hui Qi | 2007 | World Journal of Gastroenterology2007，13，10： | 8 |
| 6 | Simultaneous desulfurization and denitrogen of liquid fuels using two functionalized group ionic liquids显示文摘Deep desulfurization of liquid fuels is an important and challenging issue in worldwide petroleum refining industry.Extraction and catalytic oxidative desulfurization(ECODS)of liquid fuels using a series of ionic liquids(ILs)with two functionalized groups,such as[(CH2)2COOHmim]Cl/n Fe Cl3,[(CH2)2COOHmim]Cl/n Zn Cl2,and[Amim]Cl/n Fe Cl3,was studied.In the ECODS,the ILs were used as both extractant and catalyst and 30 wt%hydrogen peroxide(H2O2)solution as oxidant.The effects of molar ratios of[(CH2)2COOHmim]Cl(or[Amim]Cl)to Fe Cl3(or Zn Cl2)in ILs,H2O2/sulfur(O/S)molar ratio,reaction temperature,and the nature of sulfur compounds on sulfur removal were investigated.The natures of the functional groups(–COOH,–CH2–CH=CH2)in cations and the acid strength of anions play important roles in the ECODS and affect the reaction time,temperature,and desulfurization efficiency of different substrates.Also,nitrogen-containing compounds(pyridine,pyrrole,and quinoline)could be removed simultaneously in the ECODS and had different effects on dibenzothiophene removal. | NIE Yi GONG Xue GAO Hong Shuai ZHANG Xiang Ping ZHANG Suo Jiang | 2014 | Science China Chemistry2014，57，12： | 8 |
| 7 | Radiofrequency ablation technique eradicating palpebral margin neoplasm显示文摘·AIM:To report the study on radiofrequency ablation technique for eradication of palpebral margin neoplasm and its clinical effects.·METHODS:One hundred and six cases with the palpebral margin neoplasm were performed surgical removal with radiofrequency ablation technique.The 1-2 months postoperative follow-up was investigated and the lost cases were excluded from statistics.The continuing follow-up lasted about 6-16months.·RESULTS:One hundred cases underwent one treatment and 6 cases underwent two treatments.Six cases were missed.All the cases followed up healed well without pigmentation or scar left,nor eyelash loss or palpebral margin deformation.No case was recurrent.·CONCLUSION:Radiofrequency ablation has significant efficiency in eradicating the palpebral margin neoplasm.· | Tian-Yu Jiang, Hong-Yu Xiao | 2011 | International Journal of Ophthalmology(English edition)2011，4，2： | 7 |
| 8 | DNA methyltransferase3a expression is an independent poor prognostic indicator in gastric cancer显示文摘AIM: To explore the alteration of DNA methyltransferase expression in gastric cancer and to assess its prognostic value.METHODS: From April 2000 to December 2010, 227men and 73 women with gastric cancer were enrolled in the study. The expression of DNA methyltransferases(DNMTs), including DNMT1, DNMT3a and DNMT3b,in the 300 cases of gastric carcinoma, of which 85 hadpaired adjacent normal gastric mucus samples, was evaluated by immunohistochemistry using a tissue microarray. Serum anti-Helicobacter pylori(H. pylori) IgG was detected by enzyme-linked immunosorbent assay(ELISA). The relationships between the above results and the clinicopathological characteristics were analyzed. Their prognostic value was evaluated using the Cox proportional hazards model.RESULTS: In gastric cancer, expression of DNMTs was mainly seen in the nucleus. Weak staining was also observed in the cytoplasm. Expression of DNMT1, DNMT3a and DNMT3b in gastric cancer was significantly higher compared to that in the paired control samples(60.0% vs 37.6%, 61.2% vs 4.7%, and 94.1% vs 71.8%, P < 0.01). The overall survival rate was significantly higher in the DNMT3a negative group than in the DNMT3a positive group in gastric cancer patients(Log-rank test, P = 0.032). No significant correlation was observed between DNMT1 and DNMT3b expression and the overall survival time(Log-rank test, P = 0.289, P = 0.347). Multivariate regression analysis indicated that DNMT3a expression(P = 0.025) and TNM stage(P < 0.001), but not DNMT1(P = 0.54) or DNMT3b(P = 0.62), were independent prognostic factors in gastric cancer. H. pylori infection did not induce protein expression of DNMTs.CONCLUSION: The results suggest that expression of DNMT3a is an independent poor prognostic indicator in gastric cancer. DNMT3a might play an important role in gastric carcinogenesis. | Xue-Yuan Cao Hong-Xi Ma Yan-Hong Shang Mei-Shan Jin Fei Kong Zhi-Fang Jia Dong-Hui Cao Yin-Ping Wang Jian Suo Jing Jiang | 2014 | World Journal of Gastroenterology2014，20，25： | 5 |
| 9 | The RNA-binding protein Musashi2 governs osteoblast-adipocyte lineage commitment by suppressing PPARγsignaling显示文摘Osteoporosis caused by aging is characterized by reduced bone mass and accumulated adipocytes in the bone marrow cavity. How the balance between osteoblastogenesis and adipogenesis from bone marrow mesenchymal stem cells(BMSCs) is lost upon aging is still unclear. Here, we found that the RNA-binding protein Musashi2(Msi2) regulates BMSC lineage commitment. Msi2 is commonly enriched in stem cells and tumor cells. We found that its expression was downregulated during adipogenic differentiation and upregulated during osteogenic differentiation of BMSCs. Msi2 knockout mice exhibited decreased bone mass with substantial accumulation of marrow adipocytes, similar to aging-induced osteoporosis. Depletion of Msi2 in BMSCs led to increased adipocyte commitment. Transcriptional profiling analysis revealed that Msi2 deficiency led to increased PPARγ signaling.RNA-interacting protein immunoprecipitation assays demonstrated that Msi2 could inhibit the translation of the key adipogenic factor Cebpα, thereby inhibiting PPAR signaling. Furthermore, the expression of Msi2 decreased significantly during the aging process of mice, indicating that decreased Msi2 function during aging contributes to abnormal accumulation of adipocytes in bone marrow and osteoporosis. Thus, our results provide a putative biochemical mechanism for aging-related osteoporosis, suggesting that modulating Msi2 function may benefit the treatment of bone aging. | Jinlong Suo Sihai Zou Jinghui Wang Yujiao Han Lingli Zhang Chenchen Lv Bo Jiang Qian Ren Long Chen Lele Yang Ping Ji Xianyou Zheng Ping Hu Weiguo Zou | 2022 | Bone Research2022，10，3： | 5 |
| 10 | Oxidative Esterification of Methacrolein to Methyl Methacrylate over Supported Palladium Catalyst显示文摘Supported palladium catalysts, which were used in the oxidative esterification of methacrolein to methyl methacrylate, have been prepared with different carriers and Pd precursors. Experimental results revealed that Pd catalysts with γ-Al2O3 support and Na2PdCl4 precursor showed good performance. Pd catalyst modified with Pb and Mg indicated that Pd-Mg bimetallic catalyst exhibited considerably higher activity and Pd-Pb exhibited both higher activity and selectivity. 92.27% methacrolein conversion and 90.57% methyl methacrylate selectivity were obtained on Pd-Pb-Mg catalyst. | Wei ZHAO Wei Guo CHENG Zeng Xi LI Lei WANG Xiang Ping ZHANG Suo Jiang ZHANG | 2006 | Chinese Chemical Letters2006，17，6： | 3 |
| 11 | Hyperterpenoids A and B:Two pairs of unprecedented 6/6/4/6/6 polycyclic cyclobutane meroterpenoids with potent neuroprotective and anti-inflammatory activities from Hypericum beanii显示文摘Hyperterpenoid A(1)and B(2),two pairs of enantiomers,with an unprecedented 6/6/4/6/6 polycyclic skeleton,along with one known compoud hypermonone A(3)were isolated from Hypericum beanii.The racemate(±)-1 and(±)-2 were successfully separated into the two optically pure enantiomers(ee>99%)using a preparative HPLC system.Their absolute configurations were elucidated by extensive spectroscopic analyses and single-crystal X-ray diffraction method.The related plausible biogenetic pathways were pre sented.Compound 1-3 showed significant neuroprotective activity and potential antiinflammatory activity.The result that(+)-2 and(-)-2 presented different anti-inflammatory properties,may lead us to new discovery of structure activity relationship between racemates,enantiomers,and diastereomers,as well as further research regarding the binding of drugs to target proteins. | Bo Zhen Xinyue Suo Jun Dang Huilan Yue Yanduo Tao Jia-Jia Wang Li Li Ming-Bao Lin Qi Hou Wei-Ping Wang Xiao-Liang Wang Jian-Dong Jiang Teng-Fei Ji | 2021 | Chinese Chemical Letters2021，32，7： | 2 |
| 12 | Effectiveness of fast‐track rehabilitation vs conventional care in laparoscopic colorectal resection for elderly patients: a randomized trial显示文摘 | Q. Wang J. Suo J. Jiang C. Wang Y.‐Q. Zhao X. Cao | 2012 | Colorectal Disease2012，，8： | 2 |
| 13 | Increased expression of tyrosine phosphatase SHP-2 in Helicobacter pylori-infected gastric cancer显示文摘AIM:To explore the alteration of tyrosine phosphatase SHP-2 protein expression in gastric cancer and to assess its prognostic values.METHODS:Three hundred and five consecutive cases of gastric cancer were enrolled into this study.SHP-2 expression was carried out in 305 gastric cancer specimens,of which 83 were paired adjacent normal gastric mucus samples,using a tissue microarray immunohistochemical method.Correlations were analyzed between expression levels of SHP-2 protein and tumor parameters or clinical outcomes.Serum anti-Helicobacter pylori(H.pylori) immunoglobulin G was detected with enzyme-linked immunosorbent assay.Cox proportional hazards model was used to evaluate prognostic values by compassion of the expression levels of SHP-2 and disease-specific survivals in patients.RESULTS:SHP-2 staining was found diffuse mainly in the cytoplasm and the weak staining was also observed in the nucleus in gastric mucosa cells.Thirty-two point five percent of normal epithelial specimen and 62.6% of gastric cancer specimen were identified to stain with SHP-2 antibody positively(P < 0.001).Though SHP-2 staining intensities were stronger in the H.pylori(+) group than in the H.pylori(-) group,no statistically significant difference was found in the expression levels of SHP-2 between H.pylori(+) and H.pylori(-) gastric cancer(P = 0.40).The SHP-2 expression in gastric cancer was not significantly associated with cancer stages,lymph node metastases,and distant metastasis of the tumors(P = 0.34,P = 0.17,P = 0.52).Multivariate analysis demonstrated no correlation between SHP-2 expression and disease-free survival(P = 0.86).CONCLUSION:Increased expression of SHP-2 protein in gastric cancer specimen suggesting the aberrant upregulation of SHP-2 protein might play an important role in the gastric carcinogenesis. | Jing Jiang Mei-Shan Jin Fei Kong Yin-Ping Wang Zhi-Fang Jia Dong-Hui Cao Hong-Xi Ma Jian Suo Xue-Yuan Cao | 2013 | World Journal of Gastroenterology2013，19，4： | 2 |
| 14 | Extraction of coal-tar pitch using NMP/ILs mixed solvents显示文摘Coal-tar pitch(CP)is a promising carbon raw material for producing needle coke,carbon fiber etc.During processing,the H/C ratio,ash content,and quinoline insoluble(QI)in the CP are the key factors that influence the material preparation.In this study,NMP was selected to extract CP first;then[BMIM]Cl/NMP mixed solvent was used;and finally a series of ionic liquids(ILs)mixtures with NMP were developed for the extraction of CP to obtain the refined pitch.The extracts were analyzed via elemental analysis,TGA,FT-IR,and 13C-NMR.Results indicate that different NMP/IL mass ratios or different kinds of ILs have impact on the extraction yield.The relationship of the hydrogen to carbon(H/C)ratio changed with different solvents and QI extracts were obtained.Results showed that the H/C ratios changed little between NMP extracts and could be adjusted by changing the NMP/ILs mass ratio or using different ILs.The extracts are suitable for preparation mesophase pitch because of no ash content,low QI,and appropriate H/C ratios.As a result,NMP can be used to refine pitch.In addition,[BMIM]Cl is good mixed with NMP for CP extraction,because it can obtain a relatively high yield under the same extraction conditions. | HUANG Jin Cheng LI Chun Shan BAI Lu NIE Yi WANG Er Qiang HE Yu Jian ZHANG Suo Jiang | 2014 | Science China Chemistry2014，57，12： | 2 |
| 15 | Calorimetric Studies on Enthalpy Relaxation in Maltitol Glass Transition Based on Phenomenological Models显示文摘To investigate the enthalpy relaxation behavior of maltitol glass system,differential scanning calorimetry(DSC) was used to obtain the specific heat capacity[C p(T)] near the glass transition temperature(T g) at different cooling rates ranged between 1 and 20 K/min.Three phenomenological models of enthalpy relaxation,ToolNarayanaswamy-Moynihan(TNM) model,Adam-Gibbs-Vogel(AGV) model and Gómez Ribelles(GR) model,were used to simulate the experimental data.The models' parameters were obtained via a curve-fitting method.The results indicate that TNM and AGV models gave the almost identical prediction powers and can reproduce the curves of experimental C p(T) very well.However,the prediction power of GR model evolved from configurational entropy approach is not so good as those of TNM and AGV models.In particular,the metastable limit state parameter(δ) introduced by Gómez Ribelles has insignificant effect on the enthalpy relaxation of the small molecular hydrogen-bonding glass system. | YE Bin GAO Cai YANG Suo LIU Xiang-nong JIANG Bin | 2012 | Chemical Research in Chinese Universities2012，28，6： | 2 |
| 16 | Analysis of energy efficiency of air in atomizing pseudoplastic liquid using a specially designed prefilming airblast atomizer 显示文摘 | He W Z Jiang Z H Suo Q L | 2003 | Ind Eng Chem Res2003，42，13： | 1 |
| 17 | Hydrogen sul?de inhibitsmacrophage-derived foam cell formation 显示文摘 | Zhan-Zhi Zhao Zuo Wang Guo-Hua Li Ren Wang Jian- Miao Tan Xuan Cao Rong Suo and Zhi-Sheng Jiang | 2011 | Experimental Biology and Medicine2011，236，： | 1 |
| 18 | Effectiveness of Fast Track rehabilitation vs conventional care in Laparoscopic Colorectal Resection for Elderly Patients:A Randomized Trial显示文摘 | Wang Q Suo J Jiang J | | 0，，： | 1 |
| 19 | Study on temperature characteristics of organic light-emitting diodes based on tris-(8-hydroxylquinoline)-aluminum显示文摘Both single-layer and double-layer organic light-emitting devices based on tris-(8-hydroxylquinoline)-aluminum(Alq3) as emitter are fabricated by thermal vacuum deposition.The electroluminescent characteristics of these devices at various temperatures are measured,and the temperature characteristics of device performance are studied.The effect of temperature on device current conduction regime is analyzed in detail.The results show that the current-voltage(I-V) characteristics of devices are in good agreement with the theoretical prediction of trapped charge limited current(TCLC).In addition,both the charge carrier mobility and charge carrier concentration in the organic layer increase with the rise of temperature,which results in the monotonous increase of Alq3 device current.The current conduction mechanisms of two devices at different temperatures are identical,but the exponent m in current-voltage equation changes randomly with temperature.The device luminance increases slightly and the efficiency decreases monotonously due to the aging of Alq3 luminescent properties caused by high temperature.A tiny blue shift can be observed in the electroluminescent(EL) spectra as the temperature increases,and the reduction of device monochromaticity is caused by the intrinsic characteristics of organic semiconductor energy levels. | SUO Fan YU JunSheng LI WeiZhi LOU ShuangLing DENG Jing JIANG YaDong | 2008 | Chinese Science Bulletin2008，53，4： | 1 |
| 20 | Effectiveness of fast -track reha- bilitation vs conventional care in laparoscopic colorectal resection for elderly patients : a randomized trial显示文摘 | WANG Q' SUO J JIANG J | 2012 | The Association of Coloproc- tology of Great Britain and Ireland2012，14，8： | 1 |
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