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| 1 | PD-L1 is a direct target of cancer-FOXP3 in pancreatic ductal adenocarcinoma(PDAC),and combined immunotherapy with antibodies against PD-L1 and CCL5 is effective in the treatment of PDAC显示文摘High expression of PD-L1 marks the poor prognosis of pancreatic ductal adenocarcinomas(PDAC).However,the regulatory mechanism of PD-L1 remains elusive.We recently reported that cancer Forkhead box protein 3(Cancer-FOXP3 or C-FOXP3)promoted immune evasion of PDAC by recruiting Treg cells into PDAC via upregulation of CCL5.In this study,we confirmed that PD-L1 was overexpressed in PDAC samples from two independent cohorts of patients with radical resection.Moreover,C-FOXP3 was colocalized and correlated with the expression of PD-L1 in tumor cells at the mRNA and protein levels,and this finding was confirmed by the The Cancer Genome Atlas(TCGA)database.Chromatin immunoprecipitation(ChIP)revealed that C-FOXP3 directly bound to the promoter region of PD-L1 in pancreatic cancer cells.Furthermore,overexpression of C-FOXP3 activated the luciferase reporter gene under the control of the PD-L1 promoter.However,mutation of the binding motif-a completely reversed the luciferase activity.In addition,C-FOXP3-induced upregulation of PD-L1 effectively inhibited the activity of CD8+T cells.Based on our recent finding that the CCL-5 antibody achieved a better response to PDAC models with high C-FOXP3 levels,we further demonstrated that the PD-L1 antibody strengthened the antitumor effect of CCL-5 blockade in xenograft and orthotopic mouse models with high C-FOXP3 levels.In conclusion,C-FOXP3 directly activates PD-L1 and represents a core transcription factor that mediates the immune escape of PDAC.Combined blockade of PD-L1 and CCL-5 may provide an effective therapy for patients with PDAC that have high C-FOXP3 levels. | Xiuchao Wang Xin Li Xunbin Wei Haiping Jiang Chungen Lan Shengyu Yang Han Wang Yanhui Yang Caijuan Tian Zanmei Xu Jiangyan Zhang Jihui Hao He Ren | 2020 | Signal Transduction and Targeted Therapy2020，5，1： | 11 |
| 2 | Scalable synthesis of nanoporous silicon microparticles for highly cyclable lithium-ion batteries显示文摘Nanoporous silicon is a promising anode material for high energy density batteries due to its high cycling stability and high tap density compared to other nanostructured anode materials.However,the high cost of synthesis and low yield of nanoporous silicon limit its practical application.Here,we develop a scalable,low-cost top-down process of controlled oxidation of Mg2Si in the air,followed by HCl removal of MgO to generate nanoporous silicon without the use of HF.By controlling the synthesis conditions,the oxygen content,grain size and yield of the porous silicon are simultaneously optimized from commercial standpoints.In situ environmental transmission electron microscopy reveals the reaction mechanism;the Mg2Si microparticle reacts with O2 to form MgO and Si,while preventing SiO2 formation.Owing to the low oxygen content and microscale secondary structure,the nanoporous silicon delivers a higher initial reversible capacity and initial Coulombic efficiency compared to commercial Si nanoparticles(3,033 mAh/g vs.2,418 mAh/g,84.3%vs.73.1%).Synthesis is highly scalable,and a yield of 90.4%is achieved for the porous Si nanostructure with the capability to make an excess of 10 g per batch.Our synthetic nanoporous silicon is promising for practical applications in next generation lithium-ion batteries. | Jiangyan Wang William Huang Yong Seok Kim You Kyeong Jeong Sang Cheol Kim Jeffrey Heo Hiang Kwee Lee Bofei Liu Jaehou Nah Yi Cui | 2020 | Nano Research2020，13，6： | 9 |
| 3 | Enhanced hyperplasia in muscles of transgenic zebrafish expressing Follistatin1显示文摘Myostatin is a member of the transforming growth factor-β(TGF-β) super-family and functions as a negative regulator of muscle growth.Binding of the specific receptor,Activin receptor IIB(Act RIIB),with myostatin or other related TGF-β members,could be inhibited by the activin-binding protein follistatin(Fst) in mammals.Overexpressing Fst in mouse skeletal muscle leads to muscle hypertrophy and hyperplasia.To determine if Fst has similar roles in fish,we generated transgenic zebrafish expressing high levels of zebrafish Fst1 using the promoter of the zebrafish skeletal muscle-specific gene,myosin,light polypeptide 2,skeletal muscle(Mylz2).Independent transgenic zebrafish lines exhibited elevated expression levels of myogenic regulatory genes MyoD and Pax7 in muscle cells.Adult Fst1 overexpressing transgenic zebrafish exhibited a slight body weight increase.The high level of Fst1 expression dramatically increased myofiber numbers in skeletal muscle,without significantly changing the fiber size.Our findings suggest that Fst1 overexpression can promote zebrafish muscle growth by enhancing myofiber hyperplasia. | LI Xi NIE Fen YIN Zhan HE JiangYan | 2011 | Science China(Life Sciences)2011，54，2： | 8 |
| 4 | Successful Production of an All-Female Common Carp (Cyprinus carpio L.) Population Using cyp17a1-Deficient Neomale Carp显示文摘Due to sexual dimorphism in the growth of certain cultured fish species,the production of monosex fishes is desirable for the aquaculture industry.Nowadays,the most widely practiced technique available for the mass production of monosex fish populations is sex steroid-induced sex reversal.Here,a novel strategy for the successful production of all-female(AF)common carp(Cyprinus carpio L.),to take advantage of the sexual dimorphism in growth documented in this species,has been developed using genetic engineering via single gene-targeting manipulation without any exogenous hormone treatments.Male and female heterozygous cyp17a1-deficient common carp were first obtained using the clustered regularly interspaced short palindromic repeats/CRISPR-associated endonuclease 9(CRISPR/Cas9)technique.An all-male phenotype for homozygous cyp17a1-deficient carp,regardless of the individuals’sexdetermination genotypes(XY or XX),has been observed.A male-specific DNA marker newly identified in our laboratory was used to screen the neomale carp population with the XX genotype from the cyp17a1-deficient carp.These neomale carp develop a normal testis structure with normal spermatogenesis and sperm capacity.The neomale common carp were then mated with wild-type(WT)females(cyp17a1^(+/+)XX genotype)using artificial fertilization.All the AF offspring sample fish from the neomale-WT female mating were confirmed as having the cyp17a^(1+/-)XX genotype,and normal development of gonads to ovaries was observed in 100.00%of this group at eight months post-fertilization(mpf).A total of 1000 carp fingerlings,500 from the WT male and female and 500 from the neomale and WT female mating,were mixed and reared in the same pond.The average body weight of cyp17a1^(+/-)XX females was higher by 6.60%(8 mpf)and 32.66%(12 mpf)than that of the control common carp.Our study demonstrates the first successful production of a monosex teleost population with the advantages of sexual dimorphism in growth using genetic manipulation targeting a single locus. | Gang Zhai Tingting Shu Kuangxin Chen Qiyong Lou Jingyi Jia Jianfei Huang Chuang Shi Xia Jin Jiangyan He Donghuo Jiang Xueqiao Qian Wei Hu Zhan Yin | 2022 | Engineering2022，8，1： | 7 |
| 5 | Androgen signaling regulates the transcription of anti-Müllerian hormone via synergy with SRY-related protein SOX9A显示文摘Anti-Müllerian hormone(amh) is one of the earliest functional genes expressed during testicular differentiation. It has been suggested that androgen signaling regulates critical genes for the differentiation and development of the testis. To elucidate the exact regulatory mechanisms involved in amh transcription mediated by androgen signaling, androgen signaling was manipulated in zebrafish by cytochrome P45017a1(cyp17a1) knockout and Flutamide treatment. In cyp17a1-deficient and Flutamide-treated testes,up-regulated sry-box9a(sox9a) and down-regulated amh were observed. Moreover, a physical association of the zebrafish androgen receptor(AR) and SOX9 A was found. The interaction between AR and SOX9 A was mediated via the DNA binding domain(DBD) of AR and the transactivation domain(TA) of SOX9 A,and was further enhanced by 5-alpha dihydrotestosterone(DHT), one of the most potent androgens.Intriguingly, together with SOX9 A, androgen signaling synergistically promoted amh transcription,mainly through the proximal 1 kb of the amh promoter region. Taken together, our data demonstrate a critical mechanism underlying the direct synergy of androgen signaling and SOX9 A in the regulation of amh transcription. | Gang Zhai Tingting Shu Yuguo Xia Xia Jin Jiangyan He Zhan Yin | 2017 | Science Bulletin2017，62，3： | 7 |
| 6 | Accelerated Ageing Tests for Evaluations of a Durability Performance of Glass-fiber Reinforcement Polyester Composites显示文摘The paper presented accelerated ageing test results of a durability study on ortho-phthalic anhydride-type unsaturated polyester resin(191#) and its glass-fiber reinforcement polyester composites(GFRPC).The samples were exposed in an artificial xenon arc lamp ageing cell or a thermo-oxidative ageing cell.Morphology and gloss of the specimens were investigated by using a microscope and a gloss-meter,respectively.The tensile strength,bending strength and inter-laminar shear strength(ILSS) of GFRPC were tested before and after exposure,and were considered to evaluate the durability performance of this material.The polyester resin was analyzed by fourier transform infrared(FT-IR) spectroscopy.The results showed that the glossiness of the specimens got worse and some cracks appeared on their surface during the course of ageing,the tensile strength and bending strengths of the specimens first increased and then decreased.The ILSS of the composites decreased after they were aged in the xenon arc lamp cell,but increased while they were aged in the thermo-oxidative cell.The changes of these trends become more obvious during ageing in the xenon arc lamp cell,so the main influencing factor leading to the failure of this material is UV irradiation. | Yunying Wang Jiangyan Meng Qing Zhao Shuhua Qi | 2010 | Journal of Materials Science & Technology2010，26，6： | 6 |
| 7 | Human papillomavirus 16 physical status detection in preinvasive and invasive cervical carcinoma by multiplex real-time polymerase chain reaction显示文摘Objective: To explore an ideal approach for detecting the physical status of HPV-16 in clinic use and to investigate the integrated HPV-16 in CINs and cervical cancer. Methods: Multiplex real-time PCR method was established to quantify the copy numbers of E2 and E6 genes (E2/E6) for analysis of the physical status of HPV-16 DNA and this assay was compared to Southern blot analysis. HPV-16-containing paraffin-embedded tissues including 49 CINs and 51 cervical squamous cancers were detected using the method. Results: (1) The cutoff ratio of E2/E6 to distinguish pure episomal from mixed HPV-16, was 0.81 in the multiplex real-time PCR; (2) The agreement rate between multiplex real-time PCR and Southern blot was 81.5% (the Kappa statistic was 0.844, P<0.001); (3) HPV-16 DNA existed in an episomal form in 57.1% and mixed form in 42.9% of CIN I lesions; The concomitant form of HPV-16 (>70%) constituted the majority in CIN II and CIN III; HPV-16 DNA mostly integrated into the host chromosome (s) in squamous cervical cancers (68.6%); (4) The incidence of HPV-16 integration was increased with the degree of cervical lesions; (5) The frequency of pure integrated HPV-16 in stage II+III (88%) was signifi- cantly higher than that in stage I (33.3%). Conclusion: (1) Mutiplex real-time PCR provides a rapid, sensitive and reliable method for clinic detection of the physical state of HPV-16 DNA; (2) The integration of the HPV-16 DNA is a very early and important event in the progression from preinvasive to invasive cervical cancer; (3) The pure integrated status of HPV-16 in cervical cancer may be associated with poor prognosis of cervical cancer, but further study will be needed to prove its prog- nostic significance. | Ying Zheng Zhilan Peng Jiangyan Lou He Wang | 2007 | The Chinese-German Journal of Clinical Oncology2007，6，1： | 5 |
| 8 | Neuroendocrine regulation of somatic growth in fishes显示文摘Growth is a polygenic trait that is under the influence of multiple physiological pathways regulating energy metabolism and muscle growth.Among the possible growth-regulating pathways in vertebrates,components of the somatotropic axis are thought to have the greatest influence.There is growing body of literature focusing on the somatotropic axis and its role regulating growth in fish.This includes research into growth hormone,upstream hypothalamic hormones,insulin-like growth factors,and downstream signaling molecules.Many of these signals have both somatic effects stimulating the growth of tissues and metabolic effects that play a role in nutrient metabolism.Signals of other endocrine axes exhibit profound effects on the function of the somatotropic axis in vivo.In this review we highlight recent advances in our understanding of the teleost fish endocrine somatotropic axis,including emerging research using genetic modified models.These studies have revealed new aspects and challenges associated with regulation of the important steps of somatic growth. | DAI XiangYan ZHANG Wei ZHUO ZiJian HE JiangYan YIN Zhan | 2015 | Science China(Life Sciences)2015，58，2： | 5 |
| 9 | Effect of nicardipine combined with esmolol on systemic and tissue oxygenation during off-pump coronary artery bypass grafting surgery显示文摘Background The hemodynamics and oxygenation severely fluctuated during the offpump coronary artery bypass grafting (OPCABG) This study aimed at investigating whether or not nicardipine combined with esmolol (1∶10) can maintain systemic and tissue oxygenation during OPCABGMethods Twenty patients scheduled for OPCABG were divided ramdomly into Group nicardipine (N) and Group nitroglycerine (X) respectively combined with esmolol (E) (Dosage ratio: 1 to 10) (Group N+E and Group X+E) with 10 patients in each group The mixed solution of N+E or X+E were titrated to maintain mean arterial blood pressure between 70 and 80 mmHg following anesthesia induction The variables of hemodynamics, arterial blood lactate content (Lac) and gastric intramucosal partial pressure of carbon dioxide were measured at the following time points: after induction of anesthesia (T1), prerevascularization (T2), grafting of left anterior descending (T3), right coronary descending (T4) and left coronary circumflexus branches (T5), postrevascularization (T6), the end of operation (T7) The delivery of oxygen (DO2), consumption of oxygen (VO2) and gastric intramucosal pH (pHi) were calculatedResults The cardiac index (CI) in Group N+E was significantly increased (P<005) as compared with T1 during OPCABG, while it was mildly decreased in Group X+E The stroke volumes at T4, T5 in Group N+E and at T3T6 in Group X+E were significantly decreased (P<005) The systemic vascular resistance indices in Group N+E were significantly decreased as compared with T1 (P<005) The heart rates in these two Groups were significantly elevated intraoperatively (P<005) The DO2 after the infusion of N+E was significantly increased (P<005) or leveled to T1, and the Lac were within the normal range But the DO2 in Group X+E was decreased throughout the procedure, reaching significant level at T5 (P<005), and the Lac was significantly increased beyond normal range (P<005) The pHi in Group N+E was maintained above 735 during OPCABG, while it was less than 735 from T4 to T7 in Group X+EConclusion Nicardipine combined with esmolol (1∶10) regimen may maintain systemic and tissue oxygenation during | WANGTian-long JIANGYan YANGBa-xian | 2005 | Chinese Medical Journal2005，，2： | 5 |
| 10 | A novel battery scheme:Coupling nanostructured phosphorus anodes with lithium sulfide cathodes显示文摘Lithium-ion batteries are approaching their theoretical limit and can no longer keep up with the increasing demands of human society.Lithium-sulfur batteries,with a high theoretical specific energy,are promising candidates for next generation energy storage.However,the use of Li metal in Li-S batteries compromises both safety and performance,enabling dendrite formation and causing fast capacity degradation.Previous studies have probed alternative battery systems to replace the metallic Li in Li-S system,such as a Si/Li2S couple,with limited success in performance.Recently,there is a focus on red P as a favorable anode material to host Li.Here,we establish a novel battery scheme by utilizing a P/C nanocomposite anode and pairing it with a Li2S coated carbon nanofiber cathode.We find that red P anode can be compatible in ether-based electrolyte systems and can be successfully coupled to a Li2S cathode.Our proof of concept full-cell displays remarkable specific capacity,rate and cycling performances.We expect our work will provide a useful alternative system and valuable insight in the quest for next generation energy storage devices. | David Sichen Wu Guangmin Zhou Eryang Mao Yongming Sun Bofei Liu Li Wang Jiangyan Wang Feifei Shi Yi Cui | 2020 | Nano Research2020，13，5： | 4 |
| 11 | Decoding lithium batteries through advanced in situ characterization techniques显示文摘Given the energy demands of the electromobility market,the energy density and safety of lithium batteries(LBs)need to be improved,whereas its cost needs to be decreased.For the enhanced performance and decreased cost,more suitable electrode and electrolyte materials should be developed based on the improved understanding of the degradation mechanisms and structure–performance correlation in the LB system.Thus,various in situ characterization technologies have been developed during the past decades,providing abundant guidelines on the design of electrode and electrolyte materials.Here we first review the progress of in situ characterization of LBs and emphasize the feature of the multi-model coupling of different characterization techniques.Then,we systematically discuss how in situ characterization technologies reveal the electrochemical processes and fundamental mechanisms of different electrode systems based on representative electrode materials and electrolyte components.Finally,we discuss the current challenges,future opportunities,and possible directions to promote in situ characterization technologies for further improvement of the battery performance. | Mei Yang Ruyi Bi Jiangyan Wang Ranbo Yu Dan Wang | 2022 | International Journal of Minerals,Metallurgy and Materials2022，29，5： | 4 |
| 12 | Transparent perovskite glass-ceramics for visual optical thermometry显示文摘Optical thermometers have aroused considerable attention in recent years,and the increasing demand of sensitivity for practical application encourages the investigation on developing innovative non-contact optical thermo metric materials with higher sensitivity and accuracy.Perovskite quantum dots(QDs)with excellent temperature-dependence optical properties,provide a feasible approach to realizing the detection of temperature change,however,their poor high temperature thermal stability and the facile realization to obtain the production remain a daunting challenge.Herein,growing Tb^(3+)-doped CsPbl_(3) QDs in situ in borosilicate glass is proposed,which ensures the phase stability,and high-efficiency florescence output of the all-inorganic perovskite as a temperature sensor.A higher absolute and relative temperature sensitivity(0.0398 K^(-1) and 7.12%/K,respectively),along with the visible color change from orange-red to yellow-green with the increase of temperature is accomplished.Notably,the repeatable florescence intensity of Tb^(3+)-doped CsPbl_(3) QDs under high temperature enables their temperature sensing application. | Qihua Yang Lei Zhao Zhaohui Fang Ze Yang Jiangyan Cao Yiyu Cai Dacheng Zhou Xue Yu Jianbei Qiu Xuhui Xu | 2021 | Journal of Rare Earths2021，39，6： | 3 |
| 13 | The Research on Countermeasures of Green Agricultural Development in Jiangsu Province显示文摘Firstly,the thesis introduces the connotation of green agriculture,indicating that the green agriculture has 4 characteristics,namely openness,continuity,high efficiency and standardization,compared with the traditional agricultural development model.Secondly,the advantages of developing green agriculture in Jiangsu Province are discussed,namely rich agricultural resources,notable technological advantage,solid agricultural foundation,high quality of agricultural products,great market prospect of green consumption,and notable policy advantage.In view of the increasing shortage of natural resources,increasing restriction of rural labor force,increasing deterioration of rural environment,inadequate popularization of green agriculture,and fierce competition at home and abroad,the restricted factors of developing green agriculture in Jiangsu Province are introduced.Finally,in view of the agricultural concept innovation,green agricultural system innovation,agricultural technology innovation,agricultural management innovation,operation system innovation,ecological system innovation,development of tourism agriculture and regional differentiation development strategy,the relevant countermeasures and suggestions are put forward,in order to explore a new agricultural development model for Jiangsu's modern agricultural development. | DU Hua-zhang Jiangyan Municipal Bureau of Agriculture,Jiangyan 225500,China | 2010 | Asian Agricultural Research2010，2，3： | 3 |
| 14 | Hollow Micro-/Nanostructure Reviving Lithium-sulfur Batteries显示文摘Higb-energy-density lhiumslu(Li-S)bttries are drawing dramatic research interests to fulill the ever-increasing demands of etrical vehicles.However,chllenges with the insulating poperty of sulfur and its lihistion products aund its large volume expansion,aund the sutle eflet of lthiumn polysulides,hinder the commer-cial application of Li-S butteries.Lots of material design concepts have bocn developed to address the failure modes.Among them,bollw micro-/anostructures with abundant compositional und geometrical feasibility have been prored fuitful in adresing the cureut obstacles of LiS bttries Here,lypical examples of designing hollw mi-co-/anostructures to address the problemns of Li-S bttries and sinultuneously improve the practical capacity and lifespan are highlightedl.In purticular,the great efeet of structural engineering on minimizing volume change,inhi-biting the shutle efiet and catalyzing plysulide conversion are disussed systeatically. Fially fuure dreetions of hollow nanostrucure design to enhance the progress of Li-S butteries are also provided. | ZHAO Jilu YANG Mei Yang Nailiang WANG Jiangyan WANG Dan | 2020 | Chemical Research in Chinese Universities2020，36，3： | 3 |
| 15 | Multiple structural defects in ultrathin NiFe-LDH nanosheets synergistically and remarkably boost water oxidation reaction显示文摘Modifying electrocatalysts nanostructures and tuning their electronic properties through defects-oriented synthetic strategies are:essential to improve the oxygen evolution reaction(OER)performance of electrocatalysts.Current synthetic strategies about.electrocatalysts mainly target the single or double structural defects,while the researches about the synergistic effect of multiple'structural defects are rare.In this work,the ultrathin NiFe layered double hydroxide nanosheets with a holey structure,oxygen;vacancies and Ni^(3+)defects on nickel foam(NiFe-LDH-NSs/NF)are prepared by employing a simple and green H202-assisted etching 1 method.The synergistic effect ofthe above three defects leads to the exposure of.more active sites and significant improvement of:the intrinsic activity.The optimized catalyst exhibits an excellent OER performance with an extraordinarily low overpotential of 170 mV;at to mA·cm^(-2) and a small Tafel slope of 39.3 mV·dec^(-1) in 1 M KOH solution.Density functional theory calculations reveal this OER;performance arises from pseudo re-oxidized metal-stable Ni^(3+)near oxygen vacancies(O_(vac)),which suppresses 3d-e_(g) of Ni-site and!elevates d-band center towards the competitively low electron-transferbarrier.This work provides a new insight to fabricate advanced electrocatalysts for renewable energy conversion technologies. | Zhongyin Zhao Qi Shao Jiangyan Xue Bolong Huang Zheng Niu Hongwei Gu Xiaoqing Huang Jianping Lang | 2022 | Nano Research2022，15，1： | 3 |
| 16 | A stochastic logical model-based approximate solution for energy management problem of HEVs显示文摘The development of control algorithms to improve the energy efficiency of hybrid electric vehicles(HEVs)has attracted extensive attentions due to the advancement of the powertrain on fuel economy and emission reduction.The objective of the energy management control for HEVs is to distribute the driver demand power between the engine and the motor to maximize the efficiency.Deterministic dynamic programming(DP)has been applied to solve the problem,but it just | Jiangyan ZHANG Yuhu WU | 2018 | Science China(Information Sciences)2018，61，7： | 3 |
| 17 | Adaptive coordinated control of engine speed and battery charging voltage显示文摘In this paper, the control problem of auxiliary power unit (APU) for hybrid electric vehicles is investigated. An adaptive controller is provided to achieve the coordinated control between the engine speed and the battery charging voltage. The proposed adaptive coordinated control laws for the throttle angle of the engine and the voltage of the power- converter can guarantee not only the asymptotic tracking performance of the engine speed and the regulation of the battery charging voltage, but also the robust stability of the closed loop system under external load changes. Simulation results are given to verify the performance of the proposed adaptive controller. | Jiangyan ZHANG Xiaohong JIAO | 2008 | 控制理论与应用(英文版)2008，6，1： | 3 |
| 18 | Dynamical model of HEV with two planetary gear units and its application to optimization of energy consumption显示文摘A hybrid electric vehicle(HEV) that uses multiple planetary gear units with clutches as transmission system is advanced for the powertrain performance, because the operation of the clutches can lead to distinct operating modes, and the induced possible operating modes provide additional freedom to deal with the energy optimal control problem. Under each operating mode, the powertrain mechanical system has specific dynamical behavior. In order to develop model-based optimization schemes that can tackle the transient operations of the vehicle, exact dynamical modeling is investigated focusing on a hybrid powertrain system that uses a two-planetary-gear transmission box with two clutches. It shows that according to the states of the two clutches, the powertrain system has the power-split mode, parallel mode and the electric vehicle(EV) mode. Finally, an analysis for the calculation of the desired driving torque and its application to the dynamic programming(DP)-based energy management indicate the significance of the developed exact dynamical models. | Jiangyan ZHANG Shota INUZUKA Takafumi KOJIMA Tielong SHEN Junichi KAKO | 2019 | Science China(Information Sciences)2019，62，12： | 2 |
| 19 | Multimodal Emotion Recognition with Transfer Learning of Deep Neural Network显示文摘Due to the lack of large-scale emotion databases,it is hard to obtain comparable improvement in multimodal emotion recognition of the deep neural network by deep learning,which has made great progress in other areas.We use transfer learning to improve its performance with pretrained models on largescale data.Audio is encoded using deep speech recognition networks with 500 hours’speech and video is encoded using convolutional neural networks with over 110,000 images.The extracted audio and visual features are fed into Long Short-Term Memory to train models respectively.Logistic regression and ensemble method are performed in decision level fusion.The experiment results indicate that 1)audio features extracted from deep speech recognition networks achieve better performance than handcrafted audio features;2)the visual emotion recognition obtains better performance than audio emotion recognition;3)the ensemble method gets better performance than logistic regression and prior knowledge from micro-F1 value further improves the performance and robustness,achieving accuracy of 67.00%for“happy”,54.90%for“an?gry”,and 51.69%for“sad”. | HUANG Jian LI Ya TAO Jianhua YI Jiangyan | 2017 | ZTE Communications2017，15，B12： | 2 |
| 20 | Effects of the interplanetary magnetic field clock angle on the shape of bow shock显示文摘Using the global magnetohydrodynamics(MHD) simulation model, we investigated the effects of the interplanetary magnetic field(IMF) clock angle on the shape of bow shock, including its rotational asymmetry and subsolar point. For general northward IMF( z component Bz > 0), the rotational symmetry of the bow shock is broken by the effects of fast magnetosonic Mach number(Mms), and the cross-sectional line of the bow shock is an ellipse with the semi-major axis along the direction perpendicular to the IMF. The ratio or D-value between semi-major and semi-minor axis can be used to illustrate the extent of asymmetry of the bow shock. On the basis of the multiple parameters fitting, we obtain the changing relationship of both semi-axes with the clock angle and the distance away from the Earth. For general southward IMF(Bz < 0), the cross sectional line of the bow shock is highly asymmetrical under the multiple effects of magnetopause and Mms. The effects of IMF clock angle on subsolar point depend mainly on the changing subsolar point of magnetopause as an obstacle. The distance of subsolar point of bow shock from the Earth increases with the increasing IMF clock angle for Bz > 0, and decreases with the increasing IMF clock angle for Bz < 0. | WANG JiangYan HUANG ZhaoHui WANG Chi LIU ZiQian | 2015 | Science China Earth Sciences2015，58，7： | 2 |
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