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| 1 | 桑螵蛸脂类提取物对铜绿假单胞菌的抗菌活性和抗生物膜作用(英文)显示文摘目的:探究桑螵蛸脂类提取物的成分及对铜绿假单胞菌的抗菌和抗生物膜作用。创新点:中国传统中药桑螵蛸一直广泛应用于肾病的治疗,在抗菌领域未见报道,本实验首次证明桑螵蛸脂类提取物对铜绿假单胞菌有明显的抗菌和抗生物膜作用。方法:采用气相色谱-质谱联用技术,测定桑螵蛸脂质提取物的化学成分及其相对比例。采用纸片扩散法和琼脂平板稀释法观察桑螵蛸脂类提取物对铜绿假单胞菌的抑菌效应并测定最小抑制浓度(MIC)。采用结晶紫染色法和扫描电镜(SEM)进行抑制生物被膜的试验。结论:桑螵蛸脂类提取物中含有16种化合物,最丰富的成分分别是倍半萜类化合物、单萜和微量芳香族化合物。桑螵蛸脂类提取物对铜绿假单胞菌的MIC为4 mg/ml,对铜绿假单胞菌生物被膜的抑制作用明显。 | Wen-dong WANG Nan-nan ZHANG Warren CHANDA Min LIU Syed Riaz ud DIN Yun-peng DIAO Lei LIU Jing CAO Xiao-li WANG Xing-yun LI An-hong NING Min HUANG Min-tao ZHONG | 2018 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2018，19，5： | 6 |
| 2 | Evaluation of sugar and organic acid composition and their levels in highbush blueberries from two regions of China显示文摘Sweet and sour are the most important taste of blueberries,and they are produced by sugar and acid,respectively.Their contributions to the taste depend not only on the levels of sugar and acid,but also on the types and relative proportions of sugar and acid.Therefore,it is very important to evaluate the composition and levels of sugar and acid in blueberries.Regional differences and variety diversity also affect the sugar and acid characteristics of fruits.Therefore,this study selected two main producing regions in northern China(Weihai and Yingkou)to examine the sugar and acid characteristics of 11 common blueberry cultivars.The indexes measured included soluble sugars,organic acids,soluble solid content and titratable acidity.The results showed that glucose and fructose were the major sugars,and citric acid and quinic acid were the major organic acids.Correlation analysis showed that glucose,fructose,and sucrose were positively correlated with total sugar content;the citric acid content was positively correlated with the titratable acidity and total organic acids.Titratable acidity,glucose,fructose,sucrose,total sugar content,citric acid,shikimic acid and total acid content of the blueberries varied significantly between regions(P<0.05).In general,compared with Weihai blueberries,Yingkou blueberries had higher sugar content and lower acid content.The results of this study may provide useful references for the evaluation of sweet and sour flavors and cultivar selection of blueberries. | ZHANG Jia NIE Ji-yun LI Jing ZHANG Hui LI Ye Saqib FAROOQ Syed Asim Shah BACHA WANG Jie | 2020 | Journal of Integrative Agriculture2020，19，9： | 6 |
| 3 | Kudo's pit pattern classification for colorectal neoplasms:A meta-analysis显示文摘AIM:To analyze the current available evidence of Kudo's pit pattern classification for diagnosing colorectal neoplasms.METHODS:A search was performed on Pubmed/Embase to identify studies reporting the outcomes of the pit pattern classification in colorectal polyps.Retrieved records were evaluated and selected by two independent investigators.The number of patients,polyps and diagnostic performance of Kudo’s pit pattern classification were retrieved from suitable studies.Pooled sensitivities and specificities were calculated using fixed or random effect models according to their heterogeneity.Publication bias was evaluated using funnel plot,Egger’s test,and Begg’s test.Sensitivity analysis was performed by omitting one study at a time and selecting a subgroup consisting of 11 magnifying chromoendoscopy studies.RESULTS:20 eligible studies were included in which a total of 5111 colorectal lesions in 3418 patients were identified for the differentiation of neoplastic and nonneoplastic polyps.Pit pattern classification in all the studies of mucosal patterns with magnification resulted in a pooled sensitivity of 89.0%(95%CI:85.2-91.9)and pooled specificity of 85.7%(95%CI:81.3-89.2)and the area under the SROC curve was 0.9354.There was significant publication bias(P=0.038 and 0.006 for sensitivity and specificity using Egger’s test,P=0.035and 0.139 for sensitivity and specificity using Begg’s test,respectively).No single study significantly affected the pooled result,and the magnifying chromoendoscopy subgroup yielded a sensitivity of 92.7%(95%CI:89.2-95.2)and specificity of 87.3%(95%CI:81.6-91.4).CONCLUSION:Kudo’s pit pattern classification is an accurate diagnostic method for the differentiation of neoplastic colorectal lesions.Publication bias is significant in the current available literature. | Ming Li Syed Mohsin Ali Syeda Umm-a-OmarahGilani Jing Liu Yan-Qing Li Xiu-Li Zuo | 2014 | World Journal of Gastroenterology2014，20，35： | 5 |
| 4 | Effects of Vedolizumab Induction Therapy for Patients With Crohn’s Disease in Whom Tumor Necrosis Factor Antagonist Treatment Had Failed显示文摘 | Bruce E. Sands Brian G. Feagan Paul Rutgeerts Jean-Frédéric Colombel William J. Sandborn Richmond Sy Geert D’Haens Shomron Ben-Horin Jing Xu Maria Rosario Irving Fox Asit Parikh Catherine Milch Stephen Hanauer | 2014 | Gastroenterology2014，，： | 2 |
| 5 | 5-Fluorouracil inhibits nitric oxide production through the inactivation of I kappa B kinase in stomach cancer cells显示文摘 | Jing ID Yang SY Park CG | 2002 | Biochem Pharmacol2002，64，10： | 1 |
| 6 | Age - dependent renal cortical microvascular loss in female mice 显示文摘 | URBIETA -CACERES V H SYED F A LIN Jing | 2012 | American Journal of Physiology - Endocrinology and Metabolism2012，302，8： | 1 |
| 7 | Enhanced anti- tumor activity and alleviated hepatotoxicity of clotrimzole - loaded suppository using poloxamer - propylene glycol gel 显示文摘 | Chul SY Jing JX Seung HP | 2006 | Int J Pharm2006，321，12： | 1 |
| 8 | Peptidoglycan recognition protein 3and Nod2synergistically protect mice from dextran sodium sulfate-induced colitis显示文摘 | JING X ZULFIQAR F PARK SY | 2014 | J Immunol2014，193，： | 1 |
| 9 | Peptidoglycan recognition proteins protect mice from experimental colitis by promoting normal gut flora and preventing induction of interferon-gamma显示文摘 | SAHA S JING X PARK SY | 2010 | Cell Host Microbe2010，8，： | 1 |
| 10 | Inhibition of in vivo tumor angiogenesis and growth via systemic delivery of an angiopoietin 2-specific RNA aptamer显示文摘 | Shiva SY Jing M Benjamin J | | 0，，： | 1 |
| 11 | Trends in road traffic crashes and associated injury and fatality in People`s Republic of China, 1951-1999显示文摘 | Wang SY Chi GC Jing CX | 2003 | Inj Contrl Saf Promot2003，10，： | 1 |
| 12 | Exploration prospects of oil and gas in the Northwestern part of the Offshore Indus Basin, Pakistan显示文摘Oil and gas resources are short in Pakistan and no commercially viable oil and gas sources have been yet discovered in its offshore areas up to now.In this study,the onshore-offshore stratigraphic correlation and seismic data interpretation were conducted to determine the oil and gas resource potential in the Offshore Indus Basin,Pakistan.Based on the comprehensive analysis of the results and previous data,it is considered that the Cretaceous may widely exist and three sets of source rocks may be developed in the Offshore Indus Basin.The presence of Miocene mudstones has been proven by drilling to be high-quality source rocks,while the Cretaceous and Paleocene–Eocene mudstones are potential source rocks.Tectonic-lithologic traps are developed in the northwestern part of the basin affected by the strike-slip faults along Murray Ridge.Furthermore,the Cretaceous and Paleocene–Eocene source rocks are thick and are slightly affected by volcanic activities.Therefore,it can be inferred that the northwestern part of Offshore Indus Basin enjoys good prospects of oil and gas resources. | Jian-ming Gong Jing Liao Jie Liang Bao-hua Lei Jian-wen Chen Muhammad Khalid Syed Waseem Haider Ming Meng | 2020 | China Geology2020，3，4： | 1 |
| 13 | Isolation and identification of a cold-inducible gene encoding a putative DRE-binding transcription factor from Festuca arundinacea显示文摘 | Tang MJ Lu SY Jing YX | 2005 | Plant Physiology And Biochemistry2005，43，3： | 1 |
| 14 | Metformin Treatment May Increase Omentin-1 Levels in Women With Polycystic Ovary Syndrome显示文摘 | Tan Bee K Adya Raghu Farhatullah Syed Chen Jing Lelmert Hendrik Randeva Harpal S | 2010 | Diabetes2010，，12： | 1 |
| 15 | Co-overexpression of the HMGR and FPS genes enhances artemisinin content in Artemisia annua L 显示文摘 | Wang YY Jing FY Yu SY | 2011 | J Med Plants Res2011，5，： | 1 |
| 16 | Peptidoglycan recognition protein 1 enhances experimental asthma by promoting Th2 and Thl7 and limiting regulatory T cell and plasmacytoid dendritic cell responses显示文摘 | Park SY Jing X Gupta D | 2013 | J Immunol2013，190，7： | 1 |
| 17 | Efficacy of an infection control program in reducing ventilator-associated pneumo- nia in a Chinese neonatal intensive care unit 显示文摘 | Zhou Q Lee SK Jing SY | 2013 | Am J Infect Control2013，41，11： | 1 |
| 18 | Trends in road trattlc crashes and associated injury and fatality in the People's Republic of China, 1951 - 1999 显示文摘 | Wang SY Chi GB Jing CX | 2003 | Inj Control Saf Promot2003，10，12： | 1 |
| 19 | Trends in road traffic crashes and associated injury and fatality in the People's Republic of China显示文摘 | Wang SY Chi GB Jing CX | 2003 | Inj Control Saf Promot2003，10，12： | 1 |
| 20 | Peptidoglycan recog- nition proteins protect mice from experimental colitis by promoting normal gut flora and preventing induction of interferon-gamma显示文摘 | Saha S Jing X Park SY | 2010 | Cell Host Microbe2010，8，2： | 1 |
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