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| 1 | Comparison of in-vial exhaust method versus conventional exhaust method in the injection of COVID-19 vaccine显示文摘Objective:The objective of the study was to compare the application effects of in-vial exhaust method and conventional exhaust method in the process of coronavirus disease 2019 vaccine injection.Materials and Methods:Using convenient sampling method,102 vaccines were selected as experiment group during the process of vaccine injection,and the in-vial exhaust method was used.One hundred and five vaccines were selected as the control group and the conventional exhaust method was adopted.The incidence of vaccine solution spillage and exhausting time in the two groups during exhaust were observed.Results:The incidence of solution spillage in the experiment group was lower than that in the control group(0 vs.6.67%,P<0.05).The exhausting time of the experiment group was shorter than that of the control group([15.12±4.43]s vs.[22.74±6.53]s,P<0.05).Conclusion:Implementing the in-vial exhaust method in the vaccine injection can effectively reduce the incidence of solution spillage,reduce nucleic acid contamination,and ensure that the vaccine is injected at the prescribed dose.Moreover,the operation is simple and easy,which improves the nurse’s vaccination efficiency,and has a higher promotion and application value. | Jingjin XU Hui ZHI Ye LI Jinjing LIU Wen ZHENG Ling TANG | 2021 | Journal of Integrative Nursing2021，3，3： | 2 |
| 2 | Transient tribo-dynamic analysis of crosshead slipper in lowspeed marine diesel engines during engine startup显示文摘A crosshead slipper-guide system,which bears a significant thrust force,is an essential friction pair in low-speed marine diesel engines.Owing to the low moving speed of the crosshead slipper during engine startup,it is difficult to form good hydrodynamic lubrication between the crosshead slipper and guide.Therefore,a detailed analysis of the crosshead slipper during engine startup is needed.In this study,a new transient tribo-dynamic model for a crosshead slipper during the engine startup process is presented.The model consists of a mixed lubrication model of the crosshead slipper-guide and dynamic models of the piston assembly,crosshead assembly,connecting rod,and crankshaft.The tribo-dynamic performances of the crosshead slipper during startup and under the rated conditions were simulated and compared.The results show that the tribo-dynamics of the crosshead slipper during the startup process are significantly different from those under the rated conditions.Some measures beneficial for the low friction of a crosshead slipper-guide under the rated conditions may significantly increase the friction loss of the crosshead slipper-guide system during the startup process. | Rui LI Xianghui MENG Jingjin DONG Wenda LI | 2021 | Friction2021，9，6： | 2 |
| 3 | Application of five-element music therapy in pain coping skills training in patients with knee osteoarthritis显示文摘Objective:The objective of this study is to assess the application effect of five elements music therapy introduced in the pain coping skills training of knee osteoarthritis(KOA).Materials and Methods:Totally,80 patients with KOA were selected and randomly divided into the experimental group(39 cases)and the control group(41 cases).The control group was only given routine nursing measures,and the experimental group was additionally treated with five-element music therapy on the basis of the control group,twice a day,28 days in total.The Western Ontario and McMaster Universities Osteoarthritis Index(WOMAC)was used to evaluate the functional status of the knee joint of the two groups.The clinical efficacy of the two groups was evaluated by Guiding Principles for Clinical Research of New Chinese Medicine in the Treatment of Osteoarthritis.Results:WOMAC score statistically significantly decreased in the experimental group(35.92±9.48 vs.16.17±5.43,P<0.01)and the control group(36.73±6.42 vs.22.53±7.51,P<0.01)after 28 days of intervention when compared with that before intervention;WOMAC score in the experimental group was lower than that of the control group after 28 days of intervention(16.17±5.43 vs.22.53±7.51,P<0.01).The total effective rate of the experimental group was statistically higher than that of the control group(82.0%vs.51.2%,χ2=11.97,P=0.003).Conclusion:The combination of five-element music therapy and routine nursing measures has better effect in relieving pain and bad emotions of patients with KOA when compared with routine nursing measures alone. | Suqian LI Jingjin XU Ling TANG Ye LI Huaxin WANG Lixue ZHAO Jianshuang YAO Shuying WANG Nan LI | 2021 | Journal of Integrative Nursing2021，3，4： | 2 |
| 4 | Effects of statin on circulating microRNAome and predicted function regulatory network in patients with unstable angina 显示文摘 | Jingjin Li Hong Chen Jingyi Ren | 2015 | BMC Medical Genomics2015，8，12： | 1 |
| 5 | Long non-coding RNA HCAR promotes endochondral bone repair by upregulating VEGF and MMP13 in hypertrophic chondrocyte through sponging miR-15b-5p显示文摘Endochondral bone formation is an important route for bone repair.Although emerging evidence has revealed the functions of long non-coding RNAs(lncRNAs)in bone and cartilage development,the effect of lncRNAs in endochondral bone repair is still largely unknown.Here,we identified a lncRNA,named Hypertrophic Chondrocyte Angiogenesis-related lncRNA(HCAR),and proved it to promote the endochondral bone repair by upregulating the expression of matrix metallopeptidase 13(Mmp13)and vascular endothelial growth factorα(Vegfa)in hypertrophic chondrocytes.Lnc-HCAR knockdown in hypertrophic chondrocytes restrained the cartilage matrix remodeling and decrease the CD31hiEmcnhi vessels number in a bone repair model.Mechanistically,we proved that lnc-HCAR was mainly enriched in the cytoplasm using fluorescence in situ hybridization(FISH)assay,and it acted as a molecular sponge for miR-15b-5p.Further,in hypertrophic chondrocytes,lnc-HCAR competitively bound to miR-15b-5p to increase Vegfa and Mmp13 expression.Our results proved that lncRNA is deeply involved in endochondral bone repair,which will provide a new theoretical basis for future strategies for promoting fracture healing. | Yun Bai Xiaoshan Gong Rui Dong Zhen Cao Ce Dou Chuan Liu Jianmei Li Fei Kang Jingjin Dai Chunrong Zhao Zhansone Tian Jiulin Tan Qijie Dai Shiwu Dong | 2022 | Genes & Diseases2022，9，2： | 1 |
| 6 | Role of Probucol in Preventing Contrast-Induced Acute Kidney Injury After Coronary Interventional Procedure显示文摘 | Guangping Li Li Yin Tong Liu Xintian Zheng Gang Xu Yanmin Xu Ruyu Yuan Jingjin Che Hongmei Liu Lijuan Zhou Xin Chen Mei He Yiding Li Lei Wu Enzhao Liu | 2009 | The American Journal of Cardiology2009，，4： | 1 |
| 7 | Growth and physiological effects of chitosan on heat tolerance in creeping bentgrass (Agrostis stolonifera)显示文摘High temperature is one of the major abiotic stresses limiting growth and development of cool-season grass species,but chitosan could effectively enhance heat tolerance and improve plant growth.The objective of this study was to determine the optimal concentration of chitosan that could alleviate heat stress in creeping bentgrass(Agrostis stolonifera)and investigate the effects of exogenous chitosan on photosynthesis and cell membrane stability under heat stress.Under heat stress(38/28°C,day/night),different chitosan concentrations of 0,50,100 and 500 mg·L−1 were applied on the leaves of creeping bentgrass(cv.'Penn-A4').Foliar application of chitosan exhibited the positive effects on plant growth and the optimal concentration was 100 mg·L−1 which significantly improved turf quality,root length,root-shoot ratio as well as shoot and root biomass.Chitosan-treated plants subjected to high temperature stress had a lower decline in photosynthetic rate and photochemical efficiency as well as less increase in electrolyte leakage and malondialdehyde content.The results demonstrate that chitosan-improved heat tolerance as reflected by the superior growth performance of both shoot and root,photosynthesis and cell membrane stability in creeping bentgrass under heat stress. | Qiuguo Li Ruonan Li Fahui He Zhimin Yang Jingjin Yu | 2022 | Grass Research2022，2，1： | 0 |
| 8 | Operating procedures of traditional Chinese medicine breast massage显示文摘Traditional Chinese medicine breast massage,also known as breast Tuina or manual expression of breast milk,is a technique of using certain manipulations to act on specific positions or acupoints of the breast to promote blood and lymphatic circulation of breast and facilitate the discharge of stagnant milk.This technique is widely used in China to treat breastfeeding problems such as breast engorgement,mastitis,and postpartum hypogalactia.In this article,we introduce the definition and standardization process of breast massage,elaborate the operating procedures of breast massage in detail,and summarize and discuss the current situation of its clinical application,so as to provide a reference for its wide application and in‑depth research. | Jingjin XU Hong CHEN Jing ZHANG Jiaji LI Ye LI Ling TANG | 2023 | Journal of Integrative Nursing2023，5，2： | 0 |
| 9 | A Numerical Investigation on the Effects of Intake Swirl and Mixture Stratification on Combustion Characteristics in a Natural-Gas/Diesel Dual-Fuel Marine Engine显示文摘Natural gas/diesel dual-fuel combustion strategy has a great potential to reduce emissions for marine engines while the high fuel consumption is the major problem.Pre-chamber system is commonly employed as the ignition system on large-bore dual-fuel marine engines especially under lean-burn condition,due to its advanced ignition stability and engine efficiency.However,the ignition and combustion mechanism in such dual-fuel pre-chamber engine is still unclear and the effects of in-cylinder swirl flow and mixture stratification on combustion require further investigation specifically.This paper numerically studied the detailed ignition mechanism and combustion process in a marine engine equipped with a pre-chamber ignition system,and revealed the flame development process in main chamber.Moreover,the effects of mixture stratification and swirl ratio on the combustion rate and further engine thermal efficiency are investigated under decoupled condition.The results mainly show that the jet flame develops along the pre-chamber orifice centerline at the initial stage and premixed combustion play an important role,while after that,heat release zone only exist at flame surface,and premixed flame propagation controls the combustion process.In addition,with higher swirl ratio the combustion rate increases significantly due to the wider ignition area.Mixture stratification degree plays a role in accelerating the combustion,either too high or too low stratification degree reduce the combustion rate,while a moderate stratification increases the combustion rate.And appropriate stratification degree by verifying the gas injection parameters can reduce fuel consumption in 0.3%. | YE Ying LIU Haifeng LI Jingrui LIU Teng DONG Jingjin LIU Bo WU Chaohui YUE Zongyu YAO Mingfa | 2023 | Journal of Thermal Science2023，32，1： | 0 |
| 10 | Morphological characteristics of tree crowns of Cunninghamia lanceolata var. Luotian显示文摘The structural characteristics of the tree crowns of Cunninghamia lanceolata var. Luotian(herein, Luotian), a natural variety of C. lanceolata(Chinese-fir, herein Lanceolata) in China, were analyzed using trunk and branch measurements and biomass determinations. Samples from two typical cultivated varietal populations were collected, including twenty-six 15–23-year-old trees of Luotian from a plantation, and nine 16–23-year-old trees of Lanceolata. Our results show that Luotian and Lanceolata samples differed significantly in crown structure, morphological indices, and biomass:(1) the oldest live branches on Luotian trees were 5–6 years old and 8–11 years old on Lanceolata. The ages of the live branches were not affected by the ages of the Luotian trees, while live branch ages increased with ages of Lanceolata trees;(2) the maximumbranching order of Luotian was level two. Compared to Lanceolata, the average number of first-order lateral branches(i.e., branches emerging from the trunk) and the number of first-order lateral branch whorls per sample tree were 12.9% and 32.2% lower, respectively, in Luotian.However, the average number of branches within a single whorl was 21.8% greater in Luotian;the average number of branch whorls at crown height was 51.1% greater. Thus,the Luotian variety has thicker branches;(3) the average lateral branch angles in Luotian and Lanceolata sample trees were 105.2° and 61.4°, respectively. The branch angles in 53.0% of lateral branches on Luotian ranged from105° to 135°, but 30° to 90° in 96% of the lateral branches on Lanceolata. Within the same crown layer, the average branch angle was 1.6–2.2 times greater in Luotian, and the angle was directly proportional to crown thickness;(4) the average base diameter and branch length on Luotian were1.3 cm and 75.8 cm, respectively, and 1.6 cm and112.2 cm for Lanceolata. For individual trees, branch growth differed significantly(p < 0.01) between Luotian and Lanceolata. However, the lateral branches grew at a similar rate among Luotian trees of different ages;(5) the average height to the lowest live branch on Luotian was128.3% greater than on Lanceolata, resulting in a significant difference(p < 0.01) in crown size. Compared to the crowns on Lanceolata, the Luotian crowns were 45.3%higher and 41.1% wider, and the surface area, volume, and growth of the crown were 27.0%, 11.4%, and 2.4 times greater than for Lanceolata, respectively;and,(6) the biomass of Luotian and Lanceolata sample trees also differed significantly. The mean crown, branch, and leaf biomass for Luotian was 40.0%, 25.2%, and 54.1% of those for Lanceolata, respectively. However, the leaf biomass in each layer of the Luotian crown was higher thanthat of Lanceolata, and leaf biomass increased with crown thickness. | Yezhou Xu Chaoqun Du Guowei Huang Zhenfang Li Xiangyang Xu Jingjin Zheng Chu Wu | 2020 | Journal of Forestry Research2020，31，3： | 0 |
| 11 | 细菌效应蛋白揭示V-ATPase-ATG16L1通路介导异源自噬的研究显示文摘文章简介真核细胞通过选择性自噬的方式识别胞内病原体的过程称为异源自噬(xenophagy)。异源自噬在宿主天然免疫防御中发挥重要作用,但其触发机制仍不清楚。本研究通过对鼠伤寒沙门氏菌进行全基因组转座子突变筛选,鉴定出一个可强力阻断异源自噬的沙门氏菌III型分泌系统效应蛋白Sop F。更重要的是,Sop F可以抑制各种细菌感染引起的异源自噬,但不影响经典自噬通路。 | 许悦 Ping Zhou Sen Cheng Qiuhe Lu Kathrin Nowak Ann-Katrin Hopp Lin Li Xuyan Shi Zhiwei Zhou Wenqing Gao Da Li Huabin He Xiaoyun Liu Jingjin Ding Michael O.Hottiger 邵峰 | 2020 | 科学新闻2020，，2： | 0 |
| 12 | Machine learning assisted prediction of dielectric temperature spectrum of ferroelectrics显示文摘In material science and engineering,obtaining a spectrum from a measurement is often time-consuming and its accurate prediction using data mining can also be difficult.In this work,we propose a machine learning strategy based on a deep neural network model to accurately predict the dielectric temperature spectrum for a typical multi-component ferroelectric system,i.e.,(Ba_(1−x−y)Ca_(x)Sr_(y))(Ti_(1−u−v−w)Zr_(u)Sn_(v)Hf_(w))O_(3).The deep neural network model uses physical features as inputs and directly outputs the full spectrum,in addition to yielding the octahedral factor,Matyonov–Batsanov electronegativity,ratio of valence electron to nuclear charge,and core electron distance(Schubert)as four key descriptors.Owing to the physically meaningful features,our model exhibits better performance and generalization ability in the broader composition space of BaTiO3-based solid solutions.And the prediction accuracy is superior to traditional machine learning models that predict dielectric permittivity values at each temperature.Furthermore,the transition temperature and the degree of dispersion of the ferroelectric phase transition are easily extracted from the predicted spectra to provide richer physical information.The prediction is also experimentally validated by typical samples of(Ba_(0.85)Ca_(0.15))(Ti_(0.98–x)Zr_(x)Hf_(0.02))O_(3).This work provides insights for accelerating spectra predictions and extracting ferroelectric phase transition information. | Jingjin He Changxin Wang Junjie Li Chuanbao Liu Dezhen Xue Jiangli Cao Yanjing Su Lijie Qiao Turab Lookman Yang Bai | 2023 | Journal of Advanced Ceramics2023，12，9： | 0 |
| 13 | Technical operation specification for pricking-cupping therapy显示文摘Pricking-cupping therapy is a Traditional Chinese Medicine(TCM)nursing technology that can adjust the viscera of the human body,make the meridians smooth,and Yin and Yang balanced mainly by means of relieving heat and detoxification,harmonizing Qi and blood,promoting blood circulation and removing blood stasis,dredging meridians and activating collaterals,reducing swelling and pain,purging heat and calming shock,clearing heat,and opening orifices.Pricking-cupping therapy has a long history and wide application.After thousands of years of development,it has made great progress.They are widely used to treat lumbar disc herniation,herpes zoster,acute arthritis,migraine,and other diseases in China.Through the clinical practice and theoretical exploration of physicians of past dynasties,the therapeutic mechanism and application scope of pricking-cupping therapy have been greatly enriched.Modern TCM practitioners have conducted in-depth researches on the operation norms of the therapy on the basis of the ancients,hoping to grasp the essence of the disease more accurately and make the rational use of the operation technology of the therapy. | Jiaji LI Jingjin XU Jing ZHANG Ling TANG Hong CHEN Ye LI | 2023 | Journal of Integrative Nursing2023，5，3： | 0 |
| 14 | ZBTB7A governs 2-DG-inhibited glycolysis by regulating GLUT1 in nasopharyngeal carcinoma显示文摘Our previous studies suggested a potential interaction between the POK erythroid myeloid ontogenic factor ZBTB7A and glucose transporter 1(GLUT1)in nasopharyngeal carcinoma(NPC).This study was designed to confirm the interaction and further evaluate the precise mechanism by which ZBTB7A and GLUT1 regulate NPC development.The binding sites between ZBTB7A and the promoter of GLUT1 were predicted by bioinformatics.Gene expression was measured by quantitative real-time polymerase chain reaction(qPCR),western blotting,and immunohistochemistry.The activities of key glycolysis enzymes,including hexokinase(HK),pyruvate kinase(PK),lactate dehydrogenase(LDH),and lactate,were detected using specific enzyme-linked immunosorbent assay kits.The connection between ZBTB7A and GLUT1 was analyzed by dual-luciferase reporter assay and chromatin immunoprecipitation-qPCR.The vitality,proliferation,and tumorigenicity of the cells expressing different levels of ZBTB7A were tested by adding the glycolysis inhibitor 2-deoxy-D-glucose(2-DG),followed by MTT,colorimetric focus forming,and xenograft assays,respectively.Our results showed that high expression of GLUT1 was associated with late-stage NPC.After constructing stably transfected cells with lentiviruses,ZBTB7A was effectively knocked down in 5-8F cells(RNAi-5-8F)and overexpressed in 6-10B cells(ZBTB7A-6-10B).The up-or downregulation of GLUT1 secondary to ZBTB7A changes was also limited.The vitality and proliferation of the cells expressing low ZBTB7A were notably blocked by 2-DG.The cells expressing high ZBTB7A were not very sensitive to 2-DG.The growth of RNAi-5-8F xenografts was strongly suppressed by 2-DG.The activities of HK,PK,and LDH were suppressed by 2-DG in the cells expressing low ZBTB7A.RNAi-5-8F cells had the lowest 2-DG-induced lactate production.ZBTB7A directly suppressed the promoter region of GLUT1 to regulate GLUT1 expression.Thus,ZBTB7A controls the 2-DG-induced inhibition of glycolysis by affecting GLUT1. | FEI LIU JIAZHANG WEI JIAO LAN YONGLI WANG JIANXIANG YE CHENG SU MINGZHENG MO FENGZHU TANG BING LI MIN LI WEIMING DENG LINSONG YE WENLIN HUANG JINGJIN WENG WEI JIAO SHENHONG QU | 2022 | BIOCELL2022，46，12： | 0 |
| 15 | A systematic review of the efficacy of traditional Chinese medicine retention enema in the treatment of ulcerative colitis显示文摘The objective of this study is to summarize the efficacy and safety of traditional Chinese medicine(TCM)enema in the treatment of ulcerative colitis(UC).The randomized controlled trials on TCM enema intervention in the treatment of UC were searched in seven databases:PubMed,Embase,Web of Science,CBM,CNKI,Wanfang Database,and VIP Database from January 1,2013 to June 6,2022,and the data were analyzed using RevMan 5.3 software.A total of 18 studies involving 1514 UC patients were included.Meta analysis results showed that compared with conventional Western medicine,Chinese medicine enema had a significant effect on UC,and the clinical effective rate of the experimental group using Chinese medicine enema was 4.45 times that of the control group using conventional Western medicine(odds ratio=4.45,95%confidence interval[3.27,6.06]).Therefore,Chinese medicine enema is effective in the treatment of UC,and can significantly reduce related symptoms. | Jiaji LI Ling TANG Ye LI Jingjin XU Jing ZHANG | 2024 | Journal of Integrative Nursing2024，6，1： | 0 |
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