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| 1 | N6-Methyladenine DNA Methylation in Japonica and Indica Rice Genomes and Its Association with Gene Expression,Plant Development, and Stress Responses显示文摘N6-Methyladenine (6mA)DNA methylation has recently been implicated as a potential new epigenetic marker in eukaryotes,including the dioot modelArabidopsis thaliana.However,the conservation and divergence of 6mA distribution patterns and functions in plants remain elusive.Here we report high-quality 6mA methylomes at single-nucleotide resolution in rice based on substantially improved genome sequences of two rice cultivars,Nipponbare (Nip;Japonica)and 93-11 (Indica).Analysis of 6mA genomic distribution and its association with transcription suggest that 6mA distribution and function is rather conserved between rice and Arabidopsis.We found that 6mA levels are positively correlated with the expression of key stressrelated genes,which may be responsible for the difference in stress tolerance between Nip and 93-11. Moreover,we showed that mutations in DDM1 cause defects in plant growth and decreased 6mA level. Our results reveal that 6mA is a conserved DNA modification that is positively associated with gene expression and contributes to key agronomic traits in plants. | Qian Zhang Zhe Liang Xuean Cui Changmian Ji Yun Li Pingxian Zhang Jingrong Liu Adeel Riaz Pu Yao Min Liu Yunpeng Wang Tiegang Lu Hao Yu Donglei Yang Hongkun Zheng Xiaofeng Gu | 2018 | Molecular Plant2018，11，12： | 18 |
| 2 | The N^6-adenine methylation in yeast genome profiled by single-molecule technology显示文摘The most common and abundant DNA modification is 5-methylcytosine(5mC),which has been well-established as an epigenetic mark regulating gene expression in eukaryotes(Jones,2012).Another DNA modification N^6-methyldeoxyadenosine(6mA),previously reported as a widespread DNA methylation in prokaryotes, | Zhe Liang Guoliang Yu Jingrong Liu Yuke Geng Jinghui Mao Depeng Wang Jiapeng Zhou Xiaofeng Gu | 2018 | Journal of Genetics and Genomics2018，45，4： | 3 |
| 3 | Accelerating electron tomography reconstruction algorithm ICON with GPU显示文摘 | Yu Chen Zihao Wang Jingrong Zhang Lun Li Xiaohua Wan Fei Sun Fa Zhang | 2017 | Biophysics Reports2017，3，1： | 2 |
| 4 | Passivity-based Active Stabilization for DC Microgrid Applications显示文摘In this paper,an improved active stabilization strategy of the interface converters in microgrid applications is proposed on the basis of the passivity-based stability criterion(PBSC).As a critical part of AC and DC hybrid microgrids,the DC microgrid is taken as an example.In particular,a stabilization method with a proportional-integral(PI)controller and firstorder high-pass filter(HPF)is proposed to meet the passivity requirements of the overall control diagram with respect to the output voltage.Meanwhile,an output current feedback control loop is introduced to ensure the output impedance passivity.Moreover,a small-signal model of the parallel interface converter system is established to comprehensively study the influence of control parameters on the passivity of the converters.Based on the active stabilization method proposed in this study,by manipulating the control diagram of each interface converter,the passivity and stability of the DC microgrids with variable configuration can be guaranteed.Therefore,a generic and simplified design approach is realized.A simulation model with three interface converters is implemented in MATLAB/Simulink,and the effectiveness of the proposed passivity-based active stabilization algorithm is verified by using this simulation model. | Jiaqi Yu Jingrong Yu Yue Wang Yijia Cao Xiaonan Lu Dongbo Zhao | 2018 | CSEE Journal of Power and Energy Systems2018，4，1： | 2 |
| 5 | Fabrication of Miniature Silicon Water Fuel Cells With Improved Performance显示文摘 | Yu Jingrong Cheng Ping Ma Zhiqi | 2003 | J Power Sources2003，124，1： | 1 |
| 6 | Fabrication of Miniature Silicon Wafer Fuel Cells with Improved Performance显示文摘 | Yu Jingrong Cheng Ping Ma Zhiqi | 2003 | Journal of Power Sources2003，124，： | 1 |
| 7 | Development of novel self-humidifying composite membranes for fuel cells 显示文摘 | Liu Fuqiang Xing Danmin Yu Jingrong Zhang Huamin | 2003 | Journal of Power Sources2003，124，1： | 1 |
| 8 | Effect of laboratory milling on properties of starches isolated from different flour millstreams of hard and soft wheat显示文摘 | Jinglin Yu Shujun Wang Jingrong Wang | 2015 | Food Chemistry2015，172，： | 1 |
| 9 | Extraction of flocculants from a strain of Bacillus thuringiensis and analysis of their properties显示文摘In a preliminary screening study,our laboratory isolated from the biofloc in aquaculture waters a strain of Bacillus thuringiensis,which produced highly efficient bio-flocculants.In the present study,we extracted the crude flocculants from this strain and analyzed their properties.Distribution analysis indicated that the flocculants were mainly distributed in the supernatant of the fermentation liquid.The flocculants were extracted using an ethanol extraction method,and the chemical compositions and morphology of the crude flocculants were analyzed using the Molish reaction,Fehling reaction,ninhydrin reaction,biuret reaction,phenol-sulfuric acid assay,Coomassie brilliant blue staining,ultraviolet scanning,infrared scanning and scanning electron microscopy.The carbohydrate composition of the polysaccharides in the flocculants was analyzed with thin layer chromatography.The results indicated that flocculants were solid substances with an ivory white color and their texture was loose and soft.Visualization under scanning electron microscopy revealed that their ultra-morphology consisted of small,long and fiber-like shapes.Chemical and physical analyses indicated that polysaccharides accounted for 34.5%of the components in the crude flocculants.The monosaccharides present in crude flocculants included mainly glucose,galactose and mannitose. | Jingrong Wu Guangjun Wang Zhifei Li Ermeng Yu Jun Xie Zonglin Zheng | 2017 | Aquaculture and Fisheries2017，2，4： | 1 |
| 10 | Performances of Proton Exchange Membrane Fuel Cells with Alternate Membranes显示文摘 | Du Xuezhong Yu Jingrong Yi Baolian | 2001 | Phys Chem2001，，3： | 1 |
| 11 | Bexarotene combined with lapatinib for the treatment of Cushing’s disease:evidence based on drug repositioning and experimental confirmation显示文摘Dear Editor,Cushing’s disease(CD)is a rare disease manifested as Cushing’s syndrome caused by adrenocorticotropic hormone(ACTH)consistently over-secreted by adrenocorticotropic adenomas,followed by stimulation of the adrenal gland to secrete considerable cortisol,triggering metabolic dysfunction,and leading to death from complications.However,pituitary adrenocorticotropic adenoma-directed drugs can only inhibit ACTH secretion or hamper tumour growth,which limits their clinical applications.Recently,Nur77(also known as NR4A1 and NGFI-Ba,a kind of nuclear receptor),an important positive transcription regulator of pro-opiomelanocortin(POMC),the precursor of ACTH,has been regarded as a promising CD target.1 Hence,it would be promising to identify a combination treatment that targets Nur77 and another CD target to cover hormone normalisation in the short term and tumour suppression or even elimination in the long term. | Haoying Yu Shuyue Ren Jingrong Wang Tingting Lv Lan Sun Guanhua Du | 2020 | Signal Transduction and Targeted Therapy2020，5，1： | 0 |
| 12 | AutoGDeterm: Automatic Geometry Determination for Electron Tomography显示文摘Electron Tomography(ET) is an important method for studying cell ultrastructure in three-dimensional(3 D) space. By combining cryo-electron tomography of frozen-hydrated samples(cryo-ET) and a sub-tomogram averaging approach, ET has recently reached sub-nanometer resolution, thereby realizing the capability for gaining direct insights into function and mechanism. To obtain a high-resolution 3 D ET reconstruction, alignment and geometry determination of the ET tilt series are necessary. However, typical methods for determining geometry require human intervention, which is not only subjective and easily introduces errors, but is also labor intensive for high-throughput tomographic reconstructions. To overcome these problems, we have developed an automatic geometry-determination method, called Auto GDeterm. By taking advantage of the high-contrast re-projections of the Iterative Compressed-sensing Optimized Non-Uniform Fast Fourier Transform(NUFFT) reconstruction(ICON)and a series of numerical analysis methods, Auto GDeterm achieves high-precision fully automated geometry determination. Experimental results on simulated and resin-embedded datasets show that the accuracy of Auto GDeterm is high and comparable to that of the typical 'manual positioning' method. We have made Auto GDeterm available as software, which can be freely downloaded from our website http://gffzzc90893acef094d67hccqnwbuufoxb6ubf.ffgz.tsg.suse.edu.cn. | Yu Chen Zihao Wang Lun Li Jingrong Zhang Xiaohua Wan Fei Sun Fa Zhang | 2018 | Tsinghua Science and Technology2018，23，4： | 0 |
| 13 | Atramacronoids A-C,three eudesmanolide sesquiterpene-phenol hybrids with an unprecedented C-C linkage from the rhizomes of Atractylodes macrocephala显示文摘Three eudesmanolide sesquiterpene-phenol hybrids,atramacronoids A-C(1-3),featuring an unusual6/6/5/5/6 skeleton furnished by forming an unexpected C-8-C-16 linkage,were obtained from the rhizomes of Atractylodes macrocephala.Their structures and absolute configurations were elucidated by spectroscopic data analysis,chemical calculations,combined with X-ray diffractions.The plausible biosynthetic pathways for compounds 1-3 are proposed.Surprisingly,compound 1 exhibited cytotoxicity against SGC-7901 cells by inducing cells apoptosis,which might relate to the promotion of synthesis of neutrophil elastase. | Haixin Zhang Jingrong Li Jinguang Si Chengya Dong Qi Li Meng Yu Lingling Qin Lingyu Li Chenxu Zhao Tao Zhang Zhongmei Zou | 2023 | Chinese Chemical Letters2023，34，1： | 0 |
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