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| 1 | Photoresponsive organogel and organized nanostructures of cholesterol imide derivatives with azobenzene substituent groups | Tifeng Jiao Yujin Wang Fengqing Gao Jingxin Zhou Faming Gao | 2012 | Progress in Natural Science:Materials International2012，22，1： | 9 |
| 2 | Cell adhesive spectra along surface wettability gradient from superhydrophilicity to superhydrophobicity显示文摘Surface wettability is important to design biointerfaces and functional biomaterials in various biological applications. However,to date, it remains some confusions about how cells would response to the surfaces with different wettabilities. Herein,we systematically explore the adhesive spectra of cells to the surface with wettability gradient from superhydrophilicity to superhydrophobicity, clarifying the effect of wettability on cell adhesion. We envision that this study may provide valuable information for the design of biomedical implants with controllable cell adhesion, such as neural interface devices and flexible implant. | Jingxin Meng Gao Yang Lu Liu Yongyang Song Lei Jiang Shutao Wang | 2017 | Science China Chemistry2017，60，5： | 4 |
| 3 | Dual targeting of mTORC1/C2 complexes enhances histone deacetylase inhibitor-mediated anti-tumor efficacy in primary HCC cancer in vitro and in vivo显示文摘 | Huanjie Shao Chun Gao Haikuo Tang Hao Zhang Lewis R. Roberts Bonnie L. Hylander Elizabeth A. Repasky Wen W. Ma Jingxin Qiu Alex A. Adjei Grace K. Dy Chunrong Yu | 2011 | Journal of Hepatology2011，，1： | 2 |
| 4 | Research on reactive adsorption desulfurization over Ni/ZnO-SiO2- Al2O3 adsorbent in a fixed-fluidized bed reactor显示文摘 | Fan Jingxin Wang Gang Gao Jinsen | 2010 | Ind Eng Chem Res2010，49，： | 1 |
| 5 | Struction and adhension properties of linear low-density polyethylene powders grafted with acrylic acid via ultraviolet light 显示文摘 | LEI Jingxin GAO Jun JIANG Lingbo | 2006 | J Appl Polym Sci2006，100，： | 1 |
| 6 | Chemerin promotes proliferation and migration of ovarian cancer cells by upregulating expression of PD-L1显示文摘Ovarian cancer is the third-most-common malignant reproductive tumor in women.According to the American Cancer Society,it has the highest mortality rate of gynecological tumors.The five-year survival rate was only 29%during the period from 1975 to 2008(Reid et al.,2017). | Chenxi GAO Jinming SHI Jingxin ZHANG Yin LI Yi ZHANG | 2022 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2022，23，2： | 1 |
| 7 | Milk fat globule membrane supplementation protects againstβ-lactoglobul-ininduced food allergy in mice via upregulation of regulatory T cells and enhancement of intestinal barrier in a microbiota-derived short-chain fatty acids manner显示文摘Milk fat globule membrane(MFGM),which contains abundant glycoproteins and phospholipids,exerts beneficial effects on intestinal health and immunomodulation.The aim of this study was to evaluate the protective effects and possible underlying mechanisms of MFGM on cow’s milk allergy(CMA)in aβ-lactoglobulin(BLG)-induced allergic mice model.MFGM was supplemented to allergic mice induced by BLG at a dose of 400 mg/kg body weight.Results demonstrated that MFGM alleviated food allergy symptoms,decreased serum levels of lipopolysaccharide,pro-inflammatory cytokines,immunoglobulin(Ig)E,Ig G1,and Th2 cytokines including interleukin(IL)-4,while increased serum levels of Th1 cytokines including interferon-γand regulatory T cells(Tregs)cytokines including IL-10 and transforming growth factor-β.MFGM modulated gut microbiota and enhanced intestinal barrier of BLG-allergic mice,as evidenced by decreased relative abundance of Desulfobacterota,Rikenellaceae,Lachnospiraceae,and Desulfovibrionaceae,while increased relative abundance of Bacteroidetes,Lactobacillaceae and Muribaculaceae,and enhanced expressions of tight junction proteins including Occludin,Claudin-1 and zonula occludens-1.Furthermore,MFGM increased fecal short-chain fatty acids(SCFAs)levels,which elevated G protein-coupled receptor(GPR)43 and GPR109A expressions.The increased expressions of GPR43 and GPR109A induced CD103+dendritic cells accumulation and promoted Tregs differentiation in mesenteric lymph node to a certain extent.In summary,MFGM alleviated CMA in a BLG-induced allergic mice model through enhancing intestinal barrier and promoting Tregs differentiation,which may be correlated with SCFAs-mediated activation of GPRs.These findings suggest that MFGM may be useful as a promising functional ingredient against CMA. | Han Gong Tiange Li Dong Liang Jingxin Gao Xiaohan Liu Xueying Mao | 2024 | Food Science and Human Wellness2024，13，1： | 1 |
| 8 | Responses of nitrification performance,triclosan resistome and diversity of microbes to continuous triclosan stress in activated sludge system显示文摘Triclosan(TCS)is commonly found in wastewater treatment plants,which often affects biological treatment processes.The responses of nitrification,antibiotic resistome and microbial community under different TCS concentrations in activated sludge system were evaluated in this study.The experiment was conducted in a sequencing batch reactor(SBR)for 240 days.Quantitative PCR results demonstrated that the abundance of ammonium oxidizing bacteria could be temporarily inhibited by 1 mg/L TCS and then gradually recovered.And the abundances of nitrite oxidizing bacteria(NOB)under 2.5 and 4 mg/L TCS were three orders of magnitude lower than that of seed sludge,which accounted for partial nitrification.When the addition of TCS was stopped,the abundance of NOB increased.The mass balance experiments of TCS demonstrated that the primary removal pathway of TCS changed from adsorption to biodegradation as TCS was continuously added into the SBR system.Moreover,TCS increased the abundance of mexB,indicating the efflux pump might be the main TCS-resistance mechanism.As a response to TCS,bacteria could secrete more protein(PN)than polysaccharide.Three-dimensional excitation-emission matrix revealed that tryptophan PN-like substances might be the main component in PN to resist TCS.High-throughput sequencing found that the relative abundances of Paracoccus,Pseudoxanthomonas and Thauera increased,which could secrete extracellular polymeric substances(EPS).And Sphingopyxis might be the main TCS-degrading bacteria.Overall,TCS could cause partial nitrification and increase the relative abundances of EPS-secreting bacteria and TCS-degrading bacteria. | Da Zhang Jingfeng Gao Lifang Zhang Wenzhi Zhang Jingxin Jia Huihui Dai Zhiqi Wang | 2020 | Journal of Environmental Sciences2020，32，6： | 1 |
| 9 | Dual targeting of mTORC1/C2 complexes enhances histone deacetylase inhibitor-mediated anti-tumor efficacy in primary HCC cancer in vitro and in vivo显示文摘 | Huanjie Shao Chun Gao Haikuo Tang Hao Zhang Lewis R. Roberts Bonnie L. Hylander Elizabeth A. Repasky Wen W. Ma Jingxin Qiu Alex A. Adjei Grace K. Dy Chunrong Yu | 2011 | Journal of Hepatology2011，，1： | 1 |
| 10 | Detection and recognition of veterinary drug residues in beef using hyperspectral discrete wavelet transform and deep learning显示文摘A fast,non-destructive recognition method for veterinary drug residues in beef was proposed to mitigate the laborious sample preparation and long detection times associated with conventional chemical detection techniques.Control beef samples free of veterinary drug residues and four groups of beef sprayed with relevant concentrations of metronidazole,ofloxacin,salbutamol,and dexamethasone under ambient conditions were analyzed by 400-1000 nm hyperspectral imaging followed by multiplicative scatter correction preprocessing.Data dimension reduction was performed using Competitive Adaptive Reweighted Sampling(CARS),Principal Component Analysis(PCA),and Discrete Wavelet Transform(DWT)based on Haar,db3,bior1.5,sym5,and rbio1.3 wavelet basis functions.Treated data were subjected to Convolutional Neural Network(CNN),Multilayer Perceptron(MLP),Random Forest(RF),and Support Vector Machine(SVM)modelling.CNN,MLP,SVM,and RF algorithms achieved overall accuracies of 91.6%,88.6%,87.6%,and 86.2%,respectively,when combined with DWT(wavelet basis functions and numbers of transform layers being Haar-4,db3-2,bior1.5-4,and sym5-3,respectively).The algorithm Kappa coefficients(0.89,0.86,0.85,and 0.83,respectively)and time consumption for prediction(140.60 ms,57.85 ms,70.67 ms,and 87.16 ms,respectively)were also superior to models based on CARS and PCA.DWT combined with deep learning can shorten prediction times,considerably improve the accuracy of classification and recognition,and alleviate the Hughes phenomenon,thus providing a new method for the fast,non-destructive detection and recognition of veterinary drug residues in beef. | Rongchang Jiang Jingxin Shen Xinran Li Rui Gao Qinghe Zhao Zhongbin Su | 2022 | International Journal of Agricultural and Biological Engineering2022，15，1： | 0 |
| 11 | Identification of Avian-Derived Ingredients in Livestock and Poultry Meat by PCR Technology显示文摘In order to establish a quick and specific method which could identify the avian-derived ingredients,this study used 16 S rRNA gene sequence as target site,and designed the specific primers of chicken,pigeon meat and quail meat. The DNA of common livestock and poultry meat( including mutton,beef,pork,rabbit meat,pigeon meat,quail meat,chicken,duck and goose) was used as template. Though PCR amplification and specific detection,a quick determination method was established to identify the avian-derived ingredients. The results showed that the selected primers could identify the ingredients of animal origin effectively and quickly. The method was convenient and concise,and could detect the chicken-derived,pigeon-derived,quail-derived ingredients in livestock and poultry food quickly and accurately. | Jingxin ZHANG Yushi GAO Xiujun TANG Yanfeng FAN Mengjun TANG Dawei CHEN Qinglian GE Rong GU | 2016 | Asian Agricultural Research2016，8，12： | 0 |
| 12 | Interfacial assembly of a series of Cu(Ⅱ)-coordinated Schiff bases complexes:Orderly nanostructures and supramolecular chirality显示文摘Four achiral Cu(Ⅱ)-coordinated Schiff bases complexes containing aromatic structures were synthesized and their supramolecular assemblies at the air/water interface were investigated.All the compounds could be spread on water surface although they have no alkyl chains.The Schiff base complex molecules with naphthyl groups tended to form J-aggregate in the Langmuir-Blodgett(LB) films transferred from water surface.By investigation of atomic force microscopy,a multilayer film or three-dimensional structures were observed.It was interesting to note that the LB films of achiral compound Cu-NA with naphthyl segment and without methyl groups transferred from water surface showed chirality.The supramolecular chirality in the present LB films was suggested to be due to a cooperative stereoregular-stacking of the functional groups in a helical sense.This research work provides a helpful clue for regulating the nanostructures and supramolecular chiral assembly in organized films. | JIAO TiFeng LI XuHui ZHANG QingRui LI QiuRong ZHOU JingXin GAO FaMing | 2013 | Science China(Technological Sciences)2013，56，1： | 0 |
| 13 | Maternal obesity exacerbates the responsiveness of offspring BALB/c mice to cow's milk protein-induced food allergy显示文摘Food allergy has become a significant public health problem affecting a large number of people worldwide.Maternal obesity causes inflammation and alters the immune system of offspring,which may exacerbate their food allergy.The aim of this study was to determine whether offspring mice born to obese mothers would have more serve reactions to cow's milk protein-induced food allergy,and further investigate the underlying mechanisms.Female offspring BALB/c mice of mothers with normal and high-fat diets were sensitized withβ-lactoglobulin(BLG),respectively.Maternal obesity increased the serum immunoglobulin E and mouse mast cell protease levels,though did not have significant influence on anaphylactic symptom score,core temperature and diarrhea rate of offspring mice after BLG sensitization.Furthermore,maternal obesity led to a lower level of occludin mRNA expression in BLG-sensitized mice.The mice born to obese mothers exhibited increased mRNA expression levels of GATA-3,interleukin(IL)-4 and IL-10 in jejunum after BLG sensitization,indicating maternal obesity intensified Th2-type biased immune responses.In conclusion,maternal obesity exerted exacerbating effects on the responsiveness of their offspring to cow's milk protein sensitization. | Jingxin Gao Tiange Li Dong Liang Han Gong Liang Zhao Xueying Mao | 2023 | Food Science and Human Wellness2023，12，3： | 0 |
| 14 | Energy Consumption in China's Construction Industry: Energy Driving and Driven Abilities from a Regional Perspective显示文摘The construction industry is one of the largest energy consumers in China. It not only uses energy directly but also consumes a large amount of embodied energy hidden in intermediate goods and services from other industries. This paper utilizes the multi-regional input-output(MRIO)model to measure the embodied energy consumption in China's construction industry at the province level. To quantify the backward and forward linkages between the construction industry and other industries, the energy-driven and energy-driving abilities of the construction industry are investigated for 30 provinces. The results show that the values of the energy-driven coefficients are significantly larger than the energy-driving coefficients, indicating that the construction industry is highly dependent on products from other industries and other regions, not vice versa. The construction industries in the southwest and northwest regions of China have the highest energy-driven coefficients, showing that the construction industries in west China heavily rely on indirect energy embodied in goods and services. This particularly applies in Guangxi and Hainan provinces, which have the highest energydriven abilities and the lowest energy-driving abilities. The findings can facilitate the policy-makers to examine the critical energy-saving paths. | Jingxin GAO Yunong CHEN Xiaoyang ZHONG Xianrui MA | 2021 | Journal of Systems Science and Information2021，9，1： | 0 |
| 15 | Analysis of Causes of “7.21” Rainstorm in Zhongwei City显示文摘Conventional information of Micaps,NCEP reanalysis data,and data from regional automatic weather stations were used to analyze the causes of rainstorm in southern mountains of Zhongwei City on July 21,2012. The results showed that the favorable circulation situation ' high in east and low in west' to rainfall in NIngxia formed at 500 hPa before the precipitation appeared,and the heavy rainfall generated when cold air over Lake Baikal moved eastward and joined with warm and wet airflow on the northwest side of 584 line in Hetao region. Ground frontal surface and shear lines at 700 and 500 hPa were main influencing systems of heavy rainfall. Positive vorticity area at low levels,water vapor convergence,ascending motion and stratification instability provided thermal,dynamic and energy conditions for the formation of the rainstorm. The rainstorm area was situated in wind direction convergence zone where southwest airflow changed into easterly airflow at 700 hPa. Sounding data show that temperature and humidity were high in the lower atmosphere which was nearly saturated,and atmospheric convection was unstable before the rainstorm appeared. After the rainstorm occurred,energy in the atmosphere released rapidly,and each index reduced fast,so that the precipitation ended. | Bai Ling Nie Jingxin Yang Yuan Zhang Deyou Gao Jie | 2016 | Meteorological and Environmental Research2016，7，1： | 0 |
| 16 | CTCF organizes inter-A compartment interactions through RYBP-dependent phase separation显示文摘Chromatin is spatially organized into three-dimensional structures at different levels including A/B compartments, topologically associating domains and loops. The canonical CTCF-mediated loop extrusion model can explain the formation of loops. However, the organization mechanisms underlying long-range chromatin interactions such as interactions between A–A compartments are still poorly understood. Here we show that different from the canonical loop extrusion model, RYBP-mediated phase separation of CTCF organizes inter-A compartment interactions. Based on this model, we designed and verified an induced CTCF phase separation system in embryonic stem cells (ESCs), which facilitated inter-A compartment interactions, improved self-renewal of ESCs and inhibited their differentiation toward neural progenitor cells. These findings support a novel and non-canonical role of CTCF in organizing long-range chromatin interactions via phase separation. | Chao Wei Lumeng Jia Xiaona Huang Jin Tan Mulan Wang Jing Niu Yingping Hou Jun Sun Pengguihang Zeng Jia Wang Li Qing Lin Ma Xinyi Liu Xiuxiao Tang Fenjie Li Shaoshuai Jiang Jingxin Liu Tingting Li Lili Fan Yujie Sun Juntao Gao Cheng Li Junjun Ding | 2022 | Cell Research2022，32，8： | 0 |
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