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| 1 | Rapid species identification of pathogenic bacteria from a minute quantity exploiting three-dimensional quantitative phase imaging and artificial neural network显示文摘The healthcare industry is in dire need of rapid microbial identification techniques for treating microbial infections.Microbial infections are a major healthcare issue worldwide,as these widespread diseases often develop into deadly symptoms.While studies have shown that an early appropriate antibiotic treatment significantly reduces the mortality of an infection,this effective treatment is difficult to practice.The main obstacle to early appropriate antibiotic treatments is the long turnaround time of the routine microbial identification,which includes time-consuming sample growth.Here,we propose a microscopy-based framework that identifies the pathogen from single to few cells.Our framework obtains and exploits the morphology of the limited sample by incorporating three-dimensional quantitative phase imaging and an artificial neural network.We demonstrate the identification of 19 bacterial species that cause bloodstream infections,achieving an accuracy of 82.5%from an individual bacterial cell or cluster.This performance,comparable to that of the gold standard mass spectroscopy under a sufficient amount of sample,underpins the effectiveness of our framework in clinical applications.Furthermore,our accuracy increases with multiple measurements,reaching 99.9%with seven different measurements of cells or clusters.We believe that our framework can serve as a beneficial advisory tool for clinicians during the initial treatment of infections. | Geon Kim Daewoong Ahn Minhee Kang Jinho Park DongHun Ryu YoungJu Jo Jinyeop Song Jea Sung Ryu Gunho Choi Hyun Jung Chung Kyuseok Kim Doo Ryeon Chung In Young Yoo Hee Jae Huh Hyun-seok Min Nam Yong Lee YongKeun Park | 2022 | Light(Science & Applications)2022，11，7： | 2 |
| 2 | The effects of network characteristics on performance of innovation clusters显示文摘 | Jinho Choi Ahn Sang -Hyun Min-Seok Cha | 2013 | Expert Systems With Applications2013，，11： | 1 |
| 3 | Mo/Si multilayer for EUV lithography applications显示文摘 | Seng Yoon Lee Hyung Joon Kim Jinho Ahn | 2002 | J Korean Phys Soc2002，41，： | 1 |
| 4 | A causal message logging protocol for mobile nodes in mobile computing systems 显示文摘 | JinHo Ahn Sung-Gi Min Chong-Sun Hwang | 2004 | Future Generation Computer Systems2004，20，4： | 1 |
| 5 | Molecular Recognition Mediated Fabrication of Protein Nanostructures by Dip-Pen Lithography 显示文摘 | Jinho Hyun Sang Jung Ahn Woo Kyung Lee | 2002 | Nano Lett2002，2，11： | 1 |
| 6 | Synchronization of an optical frequency comb and a microwave oscillator with 53 zs/Hz^(1/2) resolution and 10^(-20) -level stability显示文摘Precise and stable synchronization between an optical frequency comb(femtosecond mode-locked laser oscillator or microresonator-based comb) and a microwave oscillator is important for various fields including telecommunication, radio astronomy, metrology, and ultrafast X-ray and electron science. Timing detection and synchronization using electro-optic sampling with an interferometer has been actively used for low-noise microwave generation, long-distance timing transfer, comb stabilization, time-of-flight sensing, and laser-microwave synchronization for ultrafast science facilities. Despite its outstanding performance, there has been a discrepancy in synchronization performance of more than 10 dB between the projected shot-noise-limited noise floor and the measured residual noise floor. In this work, we demonstrate the shot-noise-limited performance of an electro-optic timing detector-based comb-microwave synchronization, which enabled an unprecedented residual phase noise floor of -174.5 dBc∕Hz at 8 GHz carrier frequency(i.e., 53 zs∕Hz^(1/2)timing noise floor), integrated rms timing jitter of 88 as(1 Hz to 1 MHz), rms timing drift of 319 as over 12 h, and frequency instability of 3.6 × 10^(-20) over 10,000 s averaging time. We identified that bandpass filtering of the microwave signal and optical pulse repetition-rate multiplication are critical for achieving this performance. | Changmin Ahn Yongjin Na Minji Hyun Jinho Bae Jungwon Kim | 2022 | Photonics Research2022，10，2： | 0 |
| 7 | Properties of Ultra-Thin Hafnium Oxide and Interfacial Layer Deposited by Atomic Layer Deposition显示文摘Ultra-thin hafnium-oxide gate dielectric films deposited by atomic layer deposition technique using HfCl4 and H2O precursor on a hydrogen-terminated Si substrate were investigated. X-ray photoelectron spectroscopy indicates that the interface layer is Hf-silicate rather than phase separated Hf-silicide and silicon oxide structure. The Hf-silicate interfacial layer partially changes into SiOx after high temperature annealing, resulting in a complex HfO2-silicate-SiOx dielectric structure. Electrical measurements confirms that HfO2 on Si is stable up to 700 ℃ for 30 s under N2 ambient. | Taeho Lee Young-Bae Kim Kyung-Il Hong Duck-Kyun Choi Jinho Ahn | 2004 | Journal of Rare Earths2004，22，z2： | 0 |
| 8 | Unexpected Li displacement and suppressed phase transition enabling highly stabilized oxygen redox in P3-type Na layered oxide cathode显示文摘Oxygen redox is considered a new paradigm for increasing the practical capacity and energy density of the layered oxide cathodes for Na-ion batteries. However, severe local structural changes and phase transitions during anionic redox reactions lead to poor electrochemical performance with sluggish kinetics.Here, we propose a synergy of Li-Cu cations in harnessing the full potential of oxygen redox, through Li displacement and suppressed phase transition in P3-type layered oxide cathode. P3-type Na_(0.7)[Li_(0.1)Cu_(0.2)Mn_(0.7)]O_(2) cathode delivers a large specific capacity of ~212 mA h g^(-1)at 15 mA g^(-1). The discharge capacity is maintained up to ~90% of the initial capacity after 100 cycles, with stable occurrence of the oxygen redox in the high-voltage region. Through advanced experimental analyses and first-principles calculations, it is confirmed that a stepwise redox reaction based on Cu and O ions occurs for the charge-compensation mechanism upon charging. Based on a concrete understanding of the reaction mechanism, the Li displacement by the synergy of Li-Cu cations plays a crucial role in suppressing the structural change of the P3-type layered material under the oxygen redox reaction, and it is expected to be an effective strategy for stabilizing the oxygen redox in the layered oxides of Na-ion batteries. | Myungeun Choi Hobin Ahn Hyunyoung Park Yongseok Lee Jinho Ahn Bonyoung Ku Junseong Kim Wonseok Ko Jungmin Kang Jung-Keun Yoo Duho Kim Jongsoon Kim | 2023 | Journal of Energy Chemistry2023，，10： | 0 |
| 9 | Occurrence of anionic redox with absence of full oxidation to Ru^(5+) in high-energy P2-type layered oxide cathode显示文摘The anionic redox has been widely studied in layered-oxide-cathodes in attempts to achieve highenergy-density for Na-ion batteries(NIBs).It is known that an oxidation state of Mn^(4+) or Ru^(5+) is essential for the anionic reaction of O^(2-)/O~-to occur during Na^(+) de/intercalation.However,here,we report that the anionic redox can occur in Ru-based layered-oxide-cathodes before full oxidation of Ru^(4+)/Ru^(5+).Combining studies using first-principles calculation and experimental techniques reveals that further Na^(+) deintercalation from P2-Na_(0.33)[Mg_(0.33)Ru_(0.67)]O_(2) is based on anionic oxidation after 0.33 mol Na^(+) deintercalation from P2-Na_(0.67)[Mg_(0.33)Ru_(0.67)]O_(2) with cationic oxidation of Ru^(4+)/Ru^(4.5+).Especially,it is revealed that the only oxygen neighboring 2Mg/1 Ru can participate in the anionic redox during Na^(+) de/intercalation,which implies that the Na-O-Mg arrangement in the P2-Na_(0.33)[M9_(0.33)Ru_(0.67)]O_(2) structure can dramatically lower the thermodynamic stability of the anionic redox than that of cationic redox.Through the O anionic and Ru cationic reaction,P2-Na_(0.67)[Mg_(0.33)Ru_(0.67)]O_(2) exhibits not only a large specific capacity of~172 mA h g^(-1) but also excellent power-capability via facile Na^(+) diffusion and reversible structural change during charge/discharge.These findings suggest a novel strategy that can increase the activity of anionic redox by modulating the local environment around oxygen to develop high-energy-density cathode materials for NIBs. | Jinho Ahn Hyunyoung Park Wonseok Ko Yongseok Lee Jungmin Kang Seokjin Lee Sangyeop Lee Eunji Sim Kyuwook Ihm Jihyun Hong Jung-Keun Yoo Kyojin Ku Jongsoon Kim | 2023 | Journal of Energy Chemistry2023，，9： | 0 |
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