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| 1 | Fibrinogen degradation product levels on arrival for trauma patients requiring a transfusion even without head injury显示文摘BACKGROUND: There have been few reports on the clinical significance of the fibrinogen degradation product(FDP) level in trauma patients with and without head injury. We retrospectively analyzed trauma patients with or without head injury to investigate the clinical signifi cance of the FDP level.METHODS: From April 2013 to June 2015, a medical chart review was retrospectively performed for all patients with trauma. The exclusion criteria included patients who did not receive a transfusion. The patients were divided into two groups: a FDP>100 group, which included patients who had an FDP level on arrival over 100 ng/m L, and a FDP≤100 group.RESULTS: The ratio of open fractures and the prothrombin ratio in the FDP>100 group were significantly smaller than those observed in the FDP≤100 group. The average age, ratio of blunt injury, Injury Severity Score(ISS), volume of transfusion and mortality ratio in the FDP>100 group were signifi cantly greater than those in the FDP≤100 group. There was a weakly positive correlation between the FDP level and ISS(R=0.35, P=0.002), but it was not associated with the transfusion volume. The results of an analysis excluding patients with head injury showed a similar tendency.CONCLUSION: The FDP levels may be a useful biochemical parameter for the initial evaluation of the severity of trauma and mortality even in blunt traumatized patients without head injury or with stable vital signs. | Youichi Yanagawa Kouhci Ishikawa Kci Jitsuiki Toshihiko Yoshizawa Yasumasa Oodc Kazuhiko Omori Hiromichi Ohsaka | 2017 | World Journal of Emergency Medicine2017，8，2： | 4 |
| 2 | Autologous bone-marrow mononuclear cell implantation improves endothelium dependent vasodilation in patients with limb ischemia显示文摘 | Higashi Y Kimura M Hara K Noma K Jitsuiki D Nakagawa K | 2004 | Cirvulation2004，109，10： | 1 |
| 3 | Effect of edatavone, a novel free radical scavenger, on endothelium-dependent vasodilation in smokers显示文摘 | Jitsuiki D Higasbi Y Goto C | 2004 | Am J Cardiol2004，94，7： | 1 |
| 4 | Associaction of chlamtdia pneumoniae infection and carotid intima-media wall thickness in Japanese Americans显示文摘 | Jitsuiki K Yamane K Nakajima M | 2006 | Circ J2006，70，7： | 1 |
| 5 | Scarpa:s adipofascial flap for repair of wide scalp defects显示文摘 | Koshima I Inagawa K Jitsuiki Y | 1996 | Ann Plast Surg1996，36，1： | 1 |
| 6 | Prevalence of metabolic syndrome compared between native Japanese and Japanese-Americans显示文摘 | Yoneda M Yamane K Jitsuiki K | 2008 | Diabetes Res Clin Pract2008，79，3： | 1 |
| 7 | Edaravone (3 - methyl -1 - phenyl - 2 - pyrazolin -5 - one), a novel free radical scavenger, for treatment of cardiovascular diseases 显示文摘 | Higashi Y Jitsuiki D Chayama K | 2006 | Recent Pat Cardiovasc Drug Discov2006，1，1： | 1 |
| 8 | Edarvone(3-methyl-lphe- nyl-2-pyrazolin-one) ,a novel free radical scavenger, for treatment of cardiovascular diseases 显示文摘 | Higashi Y Jitsuiki D Chayama K | 2006 | Recent Patents Cardiovasc Drug Discov2006，1，： | 1 |
| 9 | Periodontal infection is associated with endothelial dysfunction in healthy subjects and hypertensive patients显示文摘 | Higashi Y Goto C Jitsuiki D | 2008 | Hypentension2008，51，2： | 1 |
| 10 | Edaravone (3-Methyl- 1-Phenyl-2-PyrazoLin-5-one), A Novel Free Radical Scavenger, for Treatment of Cardiovascular Diseases 显示文摘 | Higashi Y Jitsuiki D Chayama K | 2006 | Recent Patents Car- diovasclar Drug Discovery2006，1，： | 1 |
| 11 | Edaravone, a novel free radical scavenger, for treatment of cardiovascular diseases显示文摘 | Higashi Y Jitsuiki D Chayama K | 2006 | Recent Patents Cardiovasc Drug Discovery2006，1，： | 1 |
| 12 | Autologous Bone-Marrow Mononuclear Cell Implantation Improves Endothelium-Dependent Vasodilation in Patients With Limb Ischemia显示文摘 | Yukihito Higashi Masashi Kimura Keiko Hara Kensuke Noma Daisuke Jitsuiki Keigo Nakagawa Tetsuya Oshima Kazuaki Chayama Taijiro Sueda Chikara Goto Hiroaki Matsubara Toyoaki Murohara Masao Yoshizumi | 2004 | Circulation: Journal of the American Heart Association2004，，10： | 1 |
| 13 | Association of Chlamydia pneumoniae infection and carotid intirna-media wall thickness in Japanese Americans 显示文摘 | Jitsuiki K Yamane K Nakjima M | 2006 | Circ J2006，70，7： | 1 |
| 14 | Edaravone (3-methyl- 1-phenyl-2-pyrazolin-5-one), a novel free radical scavenger, for treatment of cardiovascular diseases 显示文摘 | Higashi Y Jitsuiki D Chayama K | 2006 | Reeent Pat Cardiovascular Drug Discovery2006，1，1： | 1 |
| 15 | Edaravone(3-methybl-phenyl-2-pyrazolin-5-one), a Novel Free Radical Scavenger, for Treatment of Cardiovascular Diseases显示文摘 | Higashi Y Jitsuiki D Chayama K | 2006 | Recent Pat Cardiovasc Drug Discov2006，1，1： | 1 |
| 16 | Edaravone ( 3-methyl-1- phen -yl-2-pyrazolin-5-one), anovel free radical scavenger, for treatment of cardiovascular Diseases显示文摘 | Higashi Y Jitsuiki D Chayama K | 2006 | Recent Pat Cardiovase Drug Discov2006，1，1： | 1 |
| 17 | Edaravone (3-methyl-1-phenyl 2 pyrazolin-5-one),a novel free radical scavenger,for treatment of cardiovascular diseases显示文摘 | Higashi Y Jitsuiki D Chayama K | | 0，，02： | 1 |
| 18 | Edaravone (3-Meth- yl-1-Phenyl-2-Pyrazolin-5-one), A novel free radical scavenger, for treatment of cardiovascular diseases 显示文摘 | Higashi Y Jitsuiki D Chayama K | 2006 | Recent Patents Cardio- vasclar Drug Discovery2006，1，： | 1 |
| 19 | Edaravone, a novelfree radical scavenger, for treatment of cardiovascular diseases显示文摘 | Higashi Y Jitsuiki D Chayama K | 2006 | Recent Patents Cardiovasc Drug Discovery2006，1，： | 1 |
| 20 | Autologous bone marrow mononuclear ceil implanta tion improves endothelium dependent vasodilation in patients with limb ischemia显示文摘 | Higashi Y Kimura M Hara K Noma K Jitsuiki D Nakagawa K | 2004 | Circulation2004，109，： | 1 |
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