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| 1 | Conversion of surgically verified unresectable to resectable hepatocellular carcinoma显示文摘 | Zhaoyou Tang Yeqin Yu Zengchen Ma Rong Yang Xinda Zhou Kangda Liu Jizhen Lu Yanming Bao Zhiying Lin Binghui Yang | 1989 | Chinese Journal of Cancer Research1989，，3： | 1 |
| 2 | Stabilization of Interconnected Nonlinear Stochastic Markoviml Jump Systems via Dis- sipativity Approach显示文摘 | LIN Zhongwei LIU Jizhen ZHANG Weihai | 2011 | Automatica2011，47，12： | 1 |
| 3 | A dynamic clustering model of wind farm based on the operation data显示文摘 | LIU Jizhen ZHU Mu LIN Zhongwei | 2015 | Journal of Renewable and Sustainable Energy2015，7，04： | 1 |
| 4 | Expression of in-duc-ible nitric oxide synthase(iNOS) in middle ear epithelial cells byIL~lb and TNF-a 显示文摘 | Weimin Li Jizhen Lin AdamsG L | 2000 | Int J Pediatric Otorhinolaryn-gology2000，55，2： | 1 |
| 5 | Analysis by cDNA microarrays of altered gene expression in middle ears of rats following pneumococcal infection显示文摘 | Jizhen Lin Yasuhiro Tsuboi Wei Pan | 2002 | Int J Ped Otorhinolaryngology2002，65，3： | 1 |
| 6 | Variable-speed technology used in power plants for better plant economics and grid stability显示文摘 | Wei Wang Jizhen Liu Deliang Zeng Zhongwei Lin Can Cui | 2012 | Energy2012，，1： | 1 |
| 7 | Expression of inducible nitric oxide synthase (iNOS) in middle ear epithelial cells by IL-1b and TNF-a显示文摘 | Weimin Li Jizhen Lin Adams G L | 2000 | Int J Pediatric Otorhinolaryngology2000，55，2： | 1 |
| 8 | R&D of BEPCII 500 MHz superconducting cavity显示文摘Beijing Electron-Positron Collider Upgrade (BEPCII) adopts two 500 MHz superconducting cavities (SCCs) in each ring for higher accelerated gradient, higher Q and lower impedance (Wang et al. The proceedings of SRF'07). There's no spare cavity due to the limited time and funding during BEPCII construction. If any serious trouble happened on either one of the two cavities and could not be recovered in a short time, the operation of BEPCII facility will be affected. Therefore, since 2009 three spare cavities have been fabricated in China to ensure reliable operation, and two of them have been successfully vertically tested in January and July 2011. This paper will briefly present the manufacture, post-process and vertical test performance of the 500 MHz spare cavities. | LIU YaPing WANG GuangWei PAN WeiMin LI JiZhen LIU DeGui SUN Yi LI ZhongQuan DAI JianPing LI ShaoPeng HE Kun WANG GuoPing ZHAO GuangYuan MA Qiang LIN HaiYing SHA Peng WANG QunYao QIU Feng MENG FanBo LI Han | 2011 | Science China(Physics,Mechanics & Astronomy)2011，54，S2： | 0 |
| 9 | Carrimycin ameliorates lipopolysaccharide and cecal ligation and puncture-induced sepsis in mice显示文摘Carrimycin(CA),sanctioned by China’s National Medical Products Administration(NMPA)in 2019 for treating acute bronchitis and sinusitis,has recently been observed to exhibit multifaceted biological activities,encompassing anti-inflammatory,antiviral,and anti-tumor properties.Despite these applications,its efficacy in sepsis treatment remains unexplored.This study introduces a novel function of CA,demonstrating its capacity to mitigate sepsis induced by lipopolysaccharide(LPS)and cecal ligation and puncture(CLP)in mice models.Our research employed in vitro assays,real-time quantitative polymerase chain reaction(RT-qPCR),and RNA-seq analysis to establish that CA significantly reduces the levels of pro-inflammatory cytokines,namely tumor necrosis factor-alpha(TNF-α),interleukin 1 beta(IL-1β),and interleukin 6(IL-6),in response to LPS stimulation.Additionally,Western blotting and immunofluorescence assays revealed that CA impedes Nuclear Factor Kappa B(NF-κB)activation in LPS-stimulated RAW264.7 cells.Complementing these findings,in vivo experiments demonstrated that CA effectively alleviates LPS-and CLP-triggered organ inflammation in C57BL/6 mice.Further insights were gained through 16S sequencing,highlighting CA’s pivotal role in enhancing gut microbiota diversity and modulating metabolic pathways,particularly by augmenting the production of short-chain fatty acids in mice subjected to CLP.Notably,a comparative analysis revealed that CA’s anti-inflammatory efficacy surpasses that of equivalent doses of aspirin(ASP)and TIENAM.Collectively,these findings suggest that CA exhibits significant therapeutic potential in sepsis treatment.This discovery provides a foundational theoretical basis for the clinical application of CA in sepsis management. | LAI Junzhong LIANG Jiadi CHEN Kunsen GUAN Biyun CHEN Zhirong CHEN Linqin FAN Jiqiang ZHANG Yong LI Qiumei SU Jingqian CHEN Qi LIN Jizhen | 2024 | Chinese Journal of Natural Medicines2024，22，3： | 0 |
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