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| 1 | IL-17 response mediates acute lung injury induced by the 2009 Pandemic Influenza A (HIN1) Virus显示文摘 | Chenggang Li Penghui Yang Yang Sun Taisheng Li Chen Wang Zhong Wang Zhen Zou Yiwu Yan Wei Wang Chen Wang Zhongwei Chen Li Xing Chong Tang Xiangwu Ju Feng Guo Jiejie Deng Yan Zhao Peng Yang Jun Tang Huanling Wang Zhongpeng Zhao Zhinan Yin Bin Cao Xiliang Wang Chengyu Jiang | 2012 | Cell Research2012，22，3： | 22 |
| 2 | Metabolic analyses reveal different mechanisms of leaf color change in two purple-leaf tea plant (Camellia sinensis L.) cultivars显示文摘Purple-leaf tea plants,as anthocyanin-rich cultivars,are valuable materials for manufacturing teas with unique colors or flavors.In this study,a new purple-leaf cultivar“Zixin”(“ZX”)was examined,and its biochemical variation and mechanism of leaf color change were elucidated.The metabolomes of leaves of“ZX”at completely purple,intermediately purple,and completely green stages were analyzed using ultra-performance liquid chromatography quadrupole time of flight mass spectrometry(UPLC-QTOF-MS).Metabolites in the flavonoid biosynthetic pathway remained at high levels in purple leaves,whereas intermediates of porphyrin and chlorophyll metabolism and carotenoid biosynthesis exhibited high levels in green leaves.In addition,fatty acid metabolism was more active in purple leaves,and steroids maintained higher levels in green leaves.Saponin,alcohol,organic acid,and terpenoid-related metabolites also changed significantly during the leaf color change process.Furthermore,the substance changes between“ZX”and“Zijuan”(a thoroughly studied purple-leaf cultivar)were also compared.The leaf color change in“Zijuan”was mainly caused by a decrease in flavonoids/anthocyanins.However,a decrease in flavonoids/anthocyanins,an enhancement of porphyrin,chlorophyll metabolism,carotenoid biosynthesis,and steroids,and a decrease in fatty acids synergistically caused the leaf color change in“ZX”.These findings will facilitate comprehensive research on the regulatory mechanisms of leaf color change in purple-leaf tea cultivars. | Jiazhi Shen Zhongwei Zou Xuzhou Zhang Lin Zhou Yuhua Wang Wanping Fang Xujun Zhu | 2018 | Horticulture Research2018，5，1： | 22 |
| 3 | The East Asian summer monsoon circulation anomaly index and its interannual variations显示文摘Based on the concept of East Asia-Pacific (EAP) teleconnection which influences East Asian summer monsoon, an index for East Asian summer monsoon circulation anomaly was defined and it was pointed out that this index can describle the interannual variation character of summer climate in East Asia, especially in the Yangtze River and Huaihe River Valley. | Gang Huang Zhongwei Yan | 1999 | Chinese Science Bulletin1999，44，14： | 18 |
| 4 | Impact of urbanization on changes in temperature extremes in Beijing during 1978–2008显示文摘To quantify the impact of urbanization on changes in observed surface air temperature and extremes,a homogenized dataset of daily mean,maximum and minimum temperature(Tm,Tmax and Tmin)observations at 20 stations in Greater Beijing(GBJ)from1978 to 2008 is analyzed.In contrast with previous studies,a cluster analysis is done to objectively classify observing stations into four categories(urbanized,suburban,rural and mountain),which is checked with remote-sensing night-light images since the1990s.At urbanized sites,there is an added warming trend in annual mean Tm representing an average of 10.9%(up to 18.4%or0.12°C/decade at the most strongly influenced site)of overall warming.Corresponding contributions for Tmin are 12.7%(up to20.8%or 0.19°C/decade)and 24%for diurnal temperature range DTR(up to 37.4%or 0.149°C/decade)over the last three decades.Although it has not had a significant impact on daytime records(Tmax),urbanization has enhanced the increasing(decreasing)trend of extremely warm(cold)nights by an average of 12.7%or 2.07 d/decade(29.0%or 5.06 d/decade)at the urbanized sites since the 1970s. | WANG Jun YAN ZhongWei LI Zhen LIU WeiDong WANG YingChun | 2013 | Chinese Science Bulletin2013，58，36： | 18 |
| 5 | Changes of climate extremes of temperature and precipitation in summer in eastern China associated with changes in atmospheric circulation in East Asia during 1960-2008显示文摘Climate extremes and changes in eastern China are closely related to variations of the East Asian summer monsoon and corresponding atmospheric circulations.The relationship between frequencies of temperature and precipitation extremes in China during the last half century is investigated using Singular Value Decomposition analysis.During 1980-1996,there was a typical pattern with fewer hot days and more precipitation extremes in the northern part of eastern China,and more hot days and fewer precipitation extremes in the southern part.This geographic pattern tended to reverse after 1997,with fewer hot days and more extreme precipitation days south of the Yangtze River and vice versa to the north.Differences in atmospheric circulation between the former and latter periods are presented.We conclude that a mid-level anomalous high/low,upper-level anomalous easterlies/westerlies over the north/south of eastern China,a weakened East Asian summer monsoon and associated upper-tropospheric center of cooling(30°N,110°E) are all favorable for the changes in frequencies of temperature and precipitation extremes. | LI Juan DONG WenJie YAN ZhongWei | 2012 | Chinese Science Bulletin2012，57，15： | 17 |
| 6 | PRMT5 regulates Golgi apparatus structure through methylation of the golgin GM130显示文摘Golgi 仪器(GA ) 的维护结构和功能取决于 Golgi 矩阵蛋白质。象 golgin 和掌握家庭的成员的 phosphorylation 那样的 Golgi 蛋白质的 posttranslational 修正为决定 Golgi 建筑学是重要的。包括 golgin-84 的一些 Golgi 蛋白质也被知道是 methylated,但是 golgin methylation 的功能仍然保持不清楚。这里,我们证明蛋白质精氨酸 methyltransferase (PRMT5 ) 5 本地化到 GA 和形式建筑群,几个部件在拴住的 GA 带子形成和泡包含了。PRMT5 在 Golgi 带子形成与 PRMT5 原因缺点的 golgin GM130,和弄空交往。而且,在 GM130 的 PRMT5 甲醇化物 N 终端精氨酸,和如此的精氨酸 methylation 为 GA 显得批评带子形成。我们的调查结果揭示 GM130 的 PRMT5 依赖的精氨酸 methylation 由控制 GA 建筑学的维护的分子的机制。 | Zhongwei Zhou Xiaotian Sun Zhenhua Zou Litao Sun Tao Zhang Shaoshi Guo Ya Wen Lin Liu Yi Wang Jun Qin Lei Li Weimin Gong Shilai Bao | 2010 | Cell Research2010，20，9： | 16 |
| 7 | Recycling of mixed cathode lithium-ion batteries for electric vehicles: Current status and future outlook显示文摘Worldwide trends in mobile electrification,largely driven by the popularity of electric vehicles(EVs)will skyrocket demands for lithium-ion battery(LIB)production.As such,up to four million metric tons of LIB waste from EV battery packs could be generated from 2015 to 2040.LIB recycling directly addresses concerns over longterm economic strains due to the uneven geographic distribution of resources(especially for Co and Li)and environmental issues associated with both landfilling and raw material extraction.However,LIB recycling infrastructure has not been widely adopted,and current facilities are mostly focused on Co recovery for economic gains.This incentive will decline due to shifting market trends from LiCoO2 toward cobalt-deficient and mixed-metal cathodes(eg,LiNi1/3Mn1/3Co1/3O2).Thus,this review covers recycling strategies to recover metals in mixed-metal LIB cathodes and comingled scrap comprising different chemistries.As such,hydrometallurgical processes can meet this criterion,while also requiring a low environmental footprint and energy consumption compared to pyrometallurgy.Following pretreatment to separate the cathode from other battery components,the active material is dissolved entirely by reductive acid leaching.A complex leachate is generated,comprising cathode metals(Li+,Ni2+,Mn2+,and Co2+)and impurities(Fe3+,Al3+,and Cu2+)from the current collectors and battery casing,which can be separated and purified using a series of selective precipitation and/or solvent extraction steps.Alternatively,the cathode can be resynthesized directly from the leachate. | Tyler Or Storm WDGourley Karthikeyan Kaliyappan Aiping Yu Zhongwei Chen | 2020 | Carbon Energy2020，2，1： | 16 |
| 8 | Matrine reduces the proliferation and invasion of colorectal cancer cells via reducing the activity of p38 signaling pathway显示文摘Matrine 被使用了在反煽动性并且反癌症治疗很长时间。然而,在 colorectal 癌症(CRC ) 的反变形的效果和相关机制仍然是不清楚的。在这研究,我们调查了 matrine 的管理是否能经由调整表明小径的 p38 禁止人的 CRC 房间的增长,活动性,和侵略。结果证明 matrine 在 vitro 并且在 vivo 禁止了 CRC 房间的移植和侵略。在为 24 h 与 matrine 被对待以后,另外,表示在 CRC 房间矩阵 metalloproteinase-2 (MMP-2 ) 和 MMP-9 以及朊酶活动铺平以一种剂量依赖者方式被减少。而且, matrine 显然减少了 p38 的 phosphorylation 水平。有 p38 禁止者(SB203580 ) 和 matrine 的联合治疗在 CRC 房间导致了侵略以及 MMP-2/-9 表示的 synergistic 减小。matrine 在 vivo 禁止了 CRC 肿瘤的增长和转移,这也被发现。在结论, p38 发信号小径可以由减少 MMP-2/-9 的表示在 CRC 房间的移植和侵略上在 matrine 的禁止的效果包含,建议 matrine 可以是为 CRC 的一个潜在的治疗学的代理人。 | Hongtao Ren Shuqun Zhang Hongbing Ma Yali Wang Di Liu Xijing Wang Zhongwei Wang | 2014 | Acta Biochimica et Biophysica Sinica2014，46，12： | 16 |
| 9 | Biomass-derived nitrogen-doped hierarchical porous carbon as efficient sulfur host for lithium–sulfur batteries显示文摘Lithium-sulfur(Li-S) battery is a potential energy storage technology with high energy density and low cost. However, the gap between theoretical expectation and practical performance limits its wide implementation. Herein, we report a nitrogen-doped porous carbon derived from biomass pomelo peel as sulfur host material for Li-S batteries. The hierarchical porous architecture and the polar surface introduced by N-doping render a favorable combination of physical and chemical sulfur confinements as well as an expedite electron/ion transfer, thus contributing to a facilitated and stabilized sulfur electrochemistry. As a result, the corresponding sulfur composite electrodes exhibit an ultrahigh initial capacity of 1534.6 mAh g^-1, high coulombic efficiency over 98% upon 300 cycles, and decent rate capability up to 2 C. This work provides an economical and effective strategy for the fabrication of advanced carbonaceous sulfur host material as well as the significant improvement of Li-S battery performance. | Qinghuiqiang Xiao Gaoran Li Minjie Li Ruiping Liu Haibo Li Pengfei Ren Yue Dong Ming Feng Zhongwei Chen | 2020 | Journal of Energy Chemistry2020，29，5： | 15 |
| 10 | The electromagnetic wave experiment for CSES mission: Search coil magnetometer显示文摘The seismic activities on the Earth can produce a disturbance of the electromagnetic field and particles in the ionosphere. The search coil magnetometer(SCM) mounted on China Seismo-Electromagnetic satellite(CSES) is designed to measure the magnetic field fluctuation of low frequency electromagnetic waves in the frequency range of 10 Hz–20 k Hz. The SCM comprises a three-axis search coil sensor mounted on a 4.5 m boom and an electronic box inside satellite module. The sampling rate of the SCM is 51.2 k Hz and the time resolution of the power spectrum density(PSD) is 2 s. The frequency resolution is 12.5 Hz.There are three operation modes: survey, detailed survey and calibration. In the survey mode, the SCM can provide a PSD in the whole frequency range of 10 Hz–20 k Hz and wave forms in the low frequency range below 2 k Hz while in the detailed survey mode the SCM can provide both PSD and wave forms in the whole frequency range of 10 Hz–20 k Hz. The sensitivity of the SCM instrument is 5.0×10^(-4) n T Hz^(-1/2) at 10 Hz, 5.0×10^(–5) n T Hz^(-1/2) at 200 Hz, 3.4×10^(-5) n T Hz^(-1/2) at 2 k Hz and 1.1×10^(-4) n T Hz^(-1/2) at 20 k Hz. The telemetry rate is ~0.85 Mbps in the survey mode and ~3.0 Mbps in the detailed survey mode. The phase difference between three axes can be made generally with a precision of less than 1.0°. The dynamic range of the SCM instrument is over 100 d B. The orthogonality of three mechanical axes of search coil senor is better than 0.13°. The performance of SCM can satisfy the requirement of scientific objectives of CSES mission. | CAO JinBin ZENG Li ZHAN Feng WANG ZuoGui WANG Yan CHEN Yu MENG QingChun JI ZhanQiang WANG PengFei LIU ZhongWei MA LingYu | 2018 | Science China(Technological Sciences)2018，61，5： | 13 |
| 11 | Genesis of the Wulong gold deposit,Liaoning Province,NE China:Constrains from noble gases,radiogenic and stable isotope studies显示文摘TheWulong lode deposit contains over 80 tonnes of gold with an average grade of 5.35 g/t.It is one of the largest deposits in Dandong City,Liaoning Province in northeast China.Previous studies on the deposit focused on its geological characteristics,geochemistry,fluid inclusions,and the timing of gold mineralization.However,controversy remains regarding the origin of the ore-forming fluids and metals,and the genesis of the gold deposit.This paper presents zircon UePb and pyrite RbeSr ages and S,Pb,He,and Ar isotopic results along with quartz H and O isotopic data for all litho-units associated with the deposit.Laser ablation inductively coupled mass spectrometry measurements yielded zircon UePb dates for samples of pre-mineralization rocks like granite porphyry dike,the Sanguliu granodiorite,fine-grained diorite,and syn-mineralization diorite,as well as post-mineralization dolerite,and lamprophyre;their emplacement ages are 1261 Ma,1241 Ma,1231 Ma,1201 Ma,1192 Ma,and 1152 Ma,respectively.The pyrite RbeSr isochron age is 1191 Ma,indicating that both magmatism and mineralization occurred during the Early Cretaceous.The d18OH2O values of ore-forming hydrothermal fluids from the quartzepolymetallic sulfide vein stage vary from 4.8&to 6.5&,and the dDV-SMOW values are between67.7&and75.9&,indicating that the ore-forming fluids were primarily magmatic.The noble gas isotope compositions of fluid inclusions hosted in pyrite suggest that the ore-forming fluids were dominantly derived from crustal sources with minor mantle input.Sulfur isotopic values of pyrite vary between 0.2&and 3.5&,suggesting that S was derived from a homogeneous magmatic source or possibly from fluids derived from the crust.The Pb isotopic compositions of sulfides(207Pb/204Pb?15.51 e15.71,206Pb/204Pb?17.35e18.75,208Pb/204Pb?38.27e40.03)indicate that the Pb of the Wulong gold deposit is a mixture of crust and mantle components.Geochronological and geochemical data,together with the regional geological history,indicate that Early Cretaceous magmatism and mineralization of the Wulong gold deposit occurred during the rollback of the subducting Paleo-Pacific Plate,which resulted in lithospheric thinning and the destruction of the North China Craton(NCC),which indicates that the deposit is of magmaticehydrothermal origin. | Peng Zhang Linlin Kou Yan Zhao Zhongwei Bi Deming Sha Renping Han Zhumin Li | 2020 | Geoscience Frontiers2020，11，2： | 13 |
| 12 | High-performance planar heterojunction perovskite solar cells: Preserving long charge carrier diffusion lengths and interracial engineering显示文摘 | Sai Bai Zhongwei Wu Xiaojing Wu Yizheng Jin Ni Zhao Zhihui Chen Qingqing Mei Xin Wang Zhizhen Ye Tao Song Ruiyuan Liu Shuit-tong Lee Baoquan Sun | 2014 | Nano Research2014，7，12： | 13 |
| 13 | Effects of water content, water type and temperature on the rheological behaviour of slag-cement and fly ash-cement paste backfill显示文摘The pumping ability and placement performance of fresh cemented paste backfill(CPB) in underground mined cavities depend on its rheological properties. Hence, it is crucial to understand the rheology of fresh CPB slurry, which is related to CPB mixture design and the temperature underground. This paper presented an experimental study investigating the effects of binder type, content, water chemical properties and content, and temperature, on the rheological properties of CPB material prepared using the tailings of a copper mine in South Australia. Portland cement(PC), a newly released commercially manufactured cement called Minecem(MC) and fly ash(FA) were used as the binders added to the mine tailing materials. Various amounts of two different water types were added to the mixtures in the preparation of backfill material slurry. Six different temperatures ranging from 5 to 60 °C were to investigate the effect of temperature on CPB rheology. Overall, the increasing water content and decreasing temperature lead to lower yield stress. Based on the results obtained from the rheological properties of CPB slurry, it was found that at room temperature(25 °C), with regards to the unconfined compressive strength(UCS) performance, the replacement of 4% PC mixed CPB(28 days UCS 425 k Pa) to 3% MC mixed CPB(28 days UCS 519 k Pa), reduced the slurry yield stress from 210.7 to 178.5 Pa. The results also showed that the chemical composition of water affects the yield stress of CPB slurry and that MC mitigates the negative effect of mine-processed water(MW) and thus lead to improve the rheological properties of the slurry. However, the results suggested that the rheological properties of a mixture using MC is very sensitive to the water volume and temperature change. Therefore, using MC in backfill requires better quality control in slump mixing. | Yue Zhao Abbas Taheri Murat Karakus Zhongwei Chen An Deng | 2020 | International Journal of Mining Science and Technology2020，30，3： | 13 |
| 14 | Homogenization of climate series:The basis for assessing climate changes显示文摘Long-term meteorological observation series are fundamental for reflecting climate changes.However,almost all meteorological stations inevitably undergo relocation or changes in observation instruments,rules,and methods,which can result in systematic biases in the observation series for corresponding periods.Homogenization is a technique for adjusting these biases in order to assess the true trends in the time series.In recent years,homogenization has shifted its focus from the adjustments to climate mean status to the adjustments to information about climate extremes or extreme weather.Using case analyses of ideal and actual climate series,here we demonstrate the basic idea of homogenization,introduce new understanding obtained from recent studies of homogenization of climate series in China,and raise issues for further studies in this field,especially with regards to climate extremes,uncertainty of the statistical adjustments,and biased physical relationships among different climate variables due to adjustments in single variable series. | YAN ZhongWei LI Zhen XIA JiangJiang | 2014 | Science China Earth Sciences2014，57，12： | 13 |
| 15 | Multidrug-resistant Tuberculosis Burden among the New Tuberculosis Patients in Zhejiang Province: An Observational Study, 2009-2013显示文摘 | Ying Peng Song-Hua Chen Le Zhang Bin Chen Ming-Wu Zhang Tie-Niu He Fei Wang Cheng-Liang Chai Lin Zhou Yu Zhang Xiao-Meng Wang Zhongwei Jia | 2017 | Chinese Medical Journal2017，，17： | 13 |
| 16 | New-generation biomedical materials:Peptide dendrimers and their application in biomedicine显示文摘Peptide dendrimers are attractive synthetic polymers and have been widely used as a new generation of biomaterials in recent years.Peptide dendrimers,as well as general dendrimers,may be synthesized to reach nano sizes,and display well-defined architectures,highly-branched structures,high density of functional terminal groups,and controllable molecular weights.On the other hand,peptide dendrimers have properties similar to proteins and some special characteristics,such as good biocompatibility,water solubility and resistance to proteolytic digestion.Due to these advantages,peptide dendrimers have received considerable attention in biomedicine.This review focuses on the development of peptide dendrimers with emphasis on their applications both in diagnostics and in therapy. | GU ZhongWei,LUO Kui,SHE WenChuan,WU Yao & HE Bin National Engineering Research Center for Biomaterials,Sichuan University,Chengdu 610064,China | 2010 | Science China Chemistry2010，53，3： | 12 |
| 17 | Aerodynamic map for soft and hard hypersonic level flight in near space显示文摘In this note,we design a velocity-altitude map forhypersonic level flight in near space of altitude 20-100 km.This map displays aerodynamic-related parameters associ-ated with near space level flight,schematically or quantita-tively.Various physical conditions for the near-space levelflight are then characterized,including laminar or turbulentflow,rarefaction or continuous flow,aerodynamic heating,aswell as conditions for sustaining level flight with and withoutorbital effect.This map allows one to identify conditions tohave soft flight or hard flight,and this identification wouldbe helpful for making correct planning on detailed studies ofaerodynamics or making initial design of near space vehicles. | Ruifeng Hu Ziniu Wu Zhe Wu Xiaoxin Wang Zhongwei Tian School of Aerospace, Tsinghua University, 100084 Beijing, China | 2009 | Acta Mechanica Sinica2009，25，4： | 11 |
| 18 | Impact of Anthropogenic Heat Release on Regional Climate in Three Vast Urban Agglomerations in China显示文摘We simulated the impact of anthropogenic heat release(AHR) on the regional climate in three vast city agglomerations in China using the Weather Research and Forecasting model with nested high-resolution modeling. Based on energy consumption and high-quality land use data, we designed two scenarios to represent no-AHR and current-AHR conditions. By comparing the results of the two numerical experiments, changes of surface air temperature and precipitation due to AHR were quantified and analyzed. We concluded that AHR increases the temperature in these urbanized areas by about 0.5℃– 1℃, and this increase is more pronounced in winter than in other seasons. The inclusion of AHR enhances the convergence of water vapor over urbanized areas. Together with the warming of the lower troposphere and the enhancement of ascending motions caused by AHR, the average convective available potential energy in urbanized areas is increased. Rainfall amounts in summer over urbanized areas are likely to increase and regional precipitation patterns to be altered to some extent. | FENG Jinming WANG Jun YAN Zhongwei | 2014 | Advances in Atmospheric Sciences2014，31，2： | 11 |
| 19 | Possible solar forcing of climate variability in the past 4000 years inferred from a proxy record at the southern margin of Tarim Basin显示文摘A ca. 4000a decadal-resolution climate proxy record of the mean grain-size from a lake (or mash) sediment at the southern margin of the Tarim Basin, correlates visu- ally with the atmospheric △14C, record from tree ring (residual △14C, solar proxy)and the GISP2 ice core 8O record (tem- peralure proxy). In general, △14 C maxima (solar minima) are coincident With cold (wet) periods in the study area and cold periods in the (;reenland ice core. Power spectrum analysis revealed statislically significant periodicities of 196a, 121a, 97a, 62a, 45a and 33—30a, which are similar to those prin- cipal solar-oscillation periods as inferred from the atmos- pheric radiocarbon and other proxy records. Possible solar forcing is addressed to be the main driving forcing of climate change in the southern margin of Tarim Basin. | ZHONGWei WANGLiguo Tyip·Tashpolat XIONGHeigang SHUQiang | 2004 | Chinese Science Bulletin2004，49，11： | 9 |
| 20 | Research and application of water jet technology in well completion and stimulation in China显示文摘In recent years, rapid progress in the use of high pressure water jets (HPWJ) has been made in oil and gas well drilling, completion, and stimulation; and good results have been achieved in field applications. Advances in technologies and developments of well completion and stimulation with hydrajet are reviewed in this paper. Experiments were conducted to study the characteristics of abrasive water jetting and to optimize jet parameters, which can provide methods for the well completion and hydrajet fracturing. Deep-penetrating hydrajet perforating can create a 2-3 m clean hole with a diameter of 20-35 mm. Multilayer hydrajet fracturing is a process whereby multiple layers are stimulated in a single run without using mechanical packers, thereby reducing operation procedure and risk. Multilateral radial wells can be drilled using hydraulic jetting up to 100 m in length. The technique to remove sand particles and plugs with rotating self-resonating cavitating water jets in horizontal wellbores has been developed and oilfield-tested, which shows promising, cost effective prospects. | Li Gensheng Huang Zhongwei Tian Shouceng Shen Zhonghou | 2010 | Petroleum Science2010，7，2： | 9 |
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