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| 1 | Impact of triple antithrombotic therapy in patients with acute coronary syndrome undergoing percutaneous coronary intervention in real-world practice显示文摘为在急性冠的症候群(交流) 和经皮的冠的干预(一种总线标准) 以后的口头的 anticoagulation (OAC ) 上的病人的 ObjectiveThe 最佳的 antithrombotic 政体仍然保持辩论。寻求回顾地在真实世界的 setting.MethodsWe 评估 OAC 正 clopidogrel 的功效和安全与或没有阿司匹林的这研究分析了数据从一国际,在 2003 和 2014 之间的多中心登记(n = 15,401 ) 。有在一种总线标准以后的交流和收到的 OAC 的病人被屏蔽。合成主要端点是 1 年的所有原因死亡,重新梗塞,或分析注册了 642 个病人包括的严重 bleeding.ResultsThe 期末考试有 OAC 和 clopidogrel (双治疗) 的 62 个病人(9.7%) ,和有阿司匹林, OAC 和 clopidogrel (三倍的治疗) 的联合的 580 个病人(90.3%) 。三倍的治疗上的病人更经常是女性的并且是更可能的有 comorbidities。关于在与三倍的治疗病人一起的双治疗之间的主要结束点没有重要差别[17.74% 对 17.24% ;unadjusted 危险比率(HR ) :1.035;95% 信心间隔(CI ) :0.556-1.929;调整 HR:1.026;95% CI:0.544-1.937 ] 。然而,重新梗塞率比三倍的治疗病人在双治疗是显著地更高的(14.52% 对 5.34% ;unadjusted HR:2.807;95% CI:1.329-5.928;调整 HR:2.333;95% CI:1.078-5.047 ) 。另外,在所有原因死亡和严重 bleeding.ConclusionsIn 的二政体之间没有差别有交流后面的一种总线标准并且与 OAC 的一个指示的真实病人,三倍的治疗没与双治疗相比与不利结果的增加的率被联系。而且,它减少了重新梗塞冒险并且没增加严重流血的风险。 | Yan YAN Xiao WANG Jing-Yao FAN Shao-Ping NIE SerGio Raooseiras-Roubin Emad Abu-Assi Jose P Simao Henriques: Fabrizio D'Ascenzo Jorge Saucedo Jose R Gonzalez-Juanate Stephen B Wilton Wouter J Kikkert Ivan Nunez-Gil Albert Ariza-Sole Xian-Tao SONG Dimitrios Alexopoulos Christoph Liebetrau Tetsuma Kawaji Claudio Morettil Zenon Huczek Toshiharu Fujii Luis cL Correia Masa-aki Kawashiri Sasko Kedev | 2017 | Journal of Geriatric Cardiology2017，14，11： | 6 |
| 2 | Gain- of-function mutations in complement factor B are associated with a- typical hemolytic uremic syndrome 显示文摘 | Goicoechea de Jorge E Harris CL Esparza-Gordillo J | 2007 | Proc Natl Acad Sci USA2007，104，： | 1 |
| 3 | Anthelmintic efficacy and management practices in sheep farms from the state of Rio de Janeiro, Brazil显示文摘 | Daniela Guedes da Cruz Letícia Oliveira da Rocha Sabrina Santos Arruda Jorge Guilherme Bergottini Palieraqui Rudymilla Cunha Cordeiro Edizio Santos Marcelo Beltr?o Molento Clóvis de Paula Santos | 2010 | Veterinary Parasitology2010，，3： | 1 |
| 4 | Genetic diversity of Plasmo- dium vivax and Plasmodium falciparum in Honduras显示文摘 | Ana CL Andres O Jorge C | 2012 | Malar- ia J2012，26，11： | 1 |
| 5 | Perforated versus Nonper- forated Acute Appendieitisz Accuracy of Multideteetor CT Detec- tion显示文摘 | Sarah DB Briart CL Jorge AS etal | 2006 | Radiology2006，241，3： | 1 |
| 6 | Gain-of-function mutations in complement factor B are associated with atypical hemolytic uremic syndrome 显示文摘 | Goicoechea de Jorge E Harris CL Esparza-Gordillo J | 2007 | Proc Natl Acad Sci U S A2007，104，1： | 1 |
| 7 | Effects of ripening on microstructure and texture of “Ameixa d’Elvas” candied plums显示文摘 | Cláudia Nunes Concei??o Santos Glória Pinto Sónia Silva José A. Lopes-da-Silva Jorge A. Saraiva Manuel A. Coimbra | 2009 | Food Chemistry2009，，3： | 1 |
| 8 | Gain-of-function mutations in complement factor B are associated with atypical hemolytic uremic syndrome 显示文摘 | Goicoechea de Jorge E Harris CL Esparza-Gordillo J | 2007 | Proc Natl Acad Sci USA2007，104，1： | 1 |
| 9 | Gain-of-function mutations in complement factor B are associated with atypical hemolytic uremic syndrome显示文摘 | GOICOECHEA DE JORGE E HARRIS CL ESPARZA-GORDILLO J | 2007 | Proc Natl Acad Sci USA2007，104，1： | 1 |
| 10 | Fixation with anchors for pos- terior cruciate ligament avulsion by arthroscopy: a new technique 显示文摘 | Felipe CA Pedro CL Jorge NS | 2005 | Arthroseopy2005，21，9： | 1 |
| 11 | Clinical characteristics and surgical outcome of patients with temporal lobe tumors and epilepsy 显示文摘 | Jorge CL Nagahashi Marie SK Pedreira CC | 2000 | Arq Neuropsiquiatr2000，58，4： | 1 |
| 12 | Effects of self-administered exercises based on Tuina techniques on musculoskeletal disorders of professional orchestra musicians: a randomized controlled trial显示文摘BACKGROUND: Musicians are frequently affected by playing-related musculoskeletal disorders(PRMD). Common solutions used by Western medicine to treat musculoskeletal pain include rehabilitation programs and drugs, but their results are sometimes disappointing.OBJECTIVE: To study the effects of self-administered exercises based on Tuina techniques on the pain intensity caused by PRMD of professional orchestra musicians, using numeric visual scale(NVS). DESIGN, SETTING, PARTICIPANTS AND INTERVENTIONS: We performed a prospective, controlled, single-blinded, randomized study with musicians suffering from PRMD. Participating musicians were randomly distributed into the experimental(n = 39) and the control(n = 30) groups. After an individual diagnostic assessment, specific Tuina self-administered exercises were developed and taught to the participants. Musicians were instructed to repeat the exercises every day for 3 weeks. MAIN OUTCOME MEASURES: Pain intensity was measured by NVS before the intervention and after 1, 3, 5, 10, 15 and 20 d of treatment. The procedure was the same for the control group, however the Tuina exercises were executed in points away from the commonly-used acupuncture points. RESULTS: In the treatment group, but not the control group, pain intensity was significantly reduced on days 1, 3, 5, 10, 15 and 20.CONCLUSION: The results obtained are consistent with the hypothesis that self-administered exercises based on Tuina techniques could help professional musicians controlling the pain caused by PRMD. Although our results are very promising, further studies are needed employing a larger sample size and double blinding designs. | Cláudia Maria Sousa Daniela Coimbra Jorge Machado Henry J.Greten | 2015 | Journal of Integrative Medicine2015，13，5： | 0 |
| 13 | Liver transplant in patients with primary sclerosing cholangitis:A retrospective cohort from Northeastern Brazil显示文摘BACKGROUND Primary sclerosing cholangitis(PSC)manifests within a broad ethnic and racial spectrum,reflecting different levels of access to health care.AIM To evaluate the clinical profile,complications and survival rates of patients with PSC undergoing liver transplantation(LTx)at a Brazilian reference center.METHODS All patients diagnosed with PSC before or after LTx were included.The medical records were reviewed for demographic and clinical variables,including outcomes and survival.The level of statistical significance was set at P<0.05.RESULTS Our cohort represented 1.6%(n=34)of the 2113 patients receiving liver grafts at our service over the past two decades.Most were male(n=19;56%).The average age(40±14 years)was similar for men and women(P=0.347).The mean follow-up time from diagnosis to LTx was 68 mo.Most patients had the classic form of PSC.Three women had PSC/autoimmune hepatitis overlap syndrome,and one patient had small-duct PSC.Alkaline phosphatase levels at diagnosis and pre-LTx model for end-stage liver disease.scores were significantly higher in males.Inflammatory bowel research(IBD)was investigated by colonoscopy in 26/34(76%)and was present in most cases(18/26;69%).IBD was less common in women than in men(44.4%vs.55.6%)(P=0.692).Cholangiocarcinoma(CCA)was diagnosed in 2/34(5.9%)patients by histopathology of the explant(survival:3 years 6 mo,and 4 years 11 mo).Two patients had complications requiring a second LTx(one after 7 d due to hepatic artery thrombosis and one after 17 d due to primary graft dysfunction).Five patients(14.7%)developed biliary stricture.The overall median post-LTx survival was 66 mo.Most deaths occurred in the first year(infection n=2,primary liver graft dysfunction n=3,unknown cause n=1).The 1-year and 5-year survival rates of this cohort were 82.3%and 70.6%,respectively,matching the mean overall survival rates of LTx patients at our center(87.1%and 69.43%,respectively)(P=0.83).CONCLUSION Survival after 1 and 5 years was similar to that of other LTx indications.The observed CCA survival rate suggests CCA may be an indication for LTx in selected cases. | Louyse Teixeira de Souza Freitas Elodie Bomfim Hyppolito Victor Leonardo Barreto Luiz Humberto JataíCastelo Júnior Bianca Carneiro de Melo Jorge Frederico César Tahim de Sousa Brasil Háteras Malthus Barbosa Marzola Clébia Azevedo Lima Raquel Mendes Celedonio Gustavo Rêgo Coelho Jose Huygens Parente Garcia | 2023 | World Journal of Hepatology2023，15，9： | 0 |
| 14 | Immediate effects of Tuina techniques on working-related musculoskeletal disorder of professional orchestra musicians显示文摘BACKGROUND:Musicians are a prone group to suffer from working-related musculoskeletal disorder(WRMD).Conventional solutions to control musculoskeletal pain include pharmacological treatment and rehabilitation programs but their effi ciency is sometimes disappointing.OBJECTIVE:The aim of this research is to study the immediate effects of Tuina techniques on WRMD of professional orchestra musicians from the north of Portugal.DESIGN,SETTING,PARTICIPANTS AND INTERVENTIONS:We performed a prospective,controlled,single-blinded,randomized study.Professional orchestra musicians with a diagnosis of WRMD were randomly distributed into the experimental group(n=39)and the control group(n=30).During an individual interview,Chinese diagnosis took place and treatment points were chosen.Real acupoints were treated by Tuina techniques into the experimental group and non-specifi c skin points were treated into the control group.Pain was measured by verbal numerical scale before and immediately after intervention.RESULTS:After one treatment session,pain was reduced in 91.8%of the cases for the experimental group and 7.9%for the control group.CONCLUSION:Although results showed that Tuina techniques are effectively reducing WRMD in professional orchestra musicians of the north of Portugal,further investigations with stronger measurements,double-blinding designs and bigger simple sizes are needed. | Cláudia Maria Sousa Luis Moreira Daniela Coimbra Jorge Machado Henry J.Greten | 2015 | Journal of Integrative Medicine2015，13，4： | 0 |
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