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| 1 | Expansion of the hepatocellular carcinoma Milan criteria in liver transplantation: Future directions显示文摘Milan criteria are currently the benchmark related to liver transplantation(LT) for hepatocellular carcinoma. However, several groups have proposed different expanded criteria with acceptable results. In this article, we review the current status of LT beyond the Milan criteria in three different scenarios-expanded criteria with cadaveric LT, downstaging to Milan criteria before LT, and expansion in the context of adult living donor LT. The review focuses on three main questions: what would the impact of the expansion beyond Milan criteria be on the patients on the waiting list; whether the dichotomous criteria(yes/no) currently used are appropriate for LT or continuous survival estimations, such as the one of 'Metroticket' and whether it should enter into the clinical practice; and, whether the use of living donor LT in the context of expansion beyond Milan criteria is justified. | Mihai-Calin Pavel Josep Fuster | 2018 | World Journal of Gastroenterology2018，24，32： | 10 |
| 2 | Prognostic factors and time-related changes influence results of colorectal liver metastases surgical treatment:A single-center analysis显示文摘AIM:To analyze the prognostic factors involved in survival and cancer recurrence in patients undergoing surgical treatment for colorectal liver metastases(CLM) and to describe the effects of time-related changes on survival and recurrence in these patients.METHODS:From January 1994 to January 2006,236 patients with CLM underwent surgery with the aim of performing curative resection of neoplastic disease at our institution and 189(80%) of these patients underwent resection of CLM with curative intention.Preoperative,intraoperative and postoperative data,including primary tumor and CLM pathology results,were retrospectively reviewed.Patients were divided into two time periods:a first period from January 1994 to January 2000(n = 93),and a second period from February 2000 to January 2006(n = 143).RESULTS:Global survival at 1,3 and 5 years in patients undergoing hepatic resection was 91%,54% and 47%,respectively.Patients with preoperative extrahepatic disease,carcinoembryonic antigen(CEA) levels over 20 ng/dL,more than four nodules or extrahepatic invasion at pathological analysis had worse survival.Tumor recurrence rate at 1 year was 48.3%,being more frequent in patients with preoperative and pathological extrahepatic disease and CEA levels over 20 ng/dL.Although patients in the second time period had more adverse prognostic factors,no differences in overall survival and recurrence were observed between the two periods.CONCLUSION:Despite advances in surgical technique and better adjuvant treatments and preoperative imaging,careful patient staging and selection is crucial to continue offering a chance of cure to patients with CLM. | Josep Martí María Marta Modolo Josep Fuster Jaume Comas Rebeca Cosa Joana Ferrer Victor Molina Juan Romero Constantino Fondevila Ramón Charco Juan Carlos García-Valdecasas | 2009 | World Journal of Gastroenterology2009，15，21： | 9 |
| 3 | Graft and viral outcomes in retransplantation for hepatitis C virus recurrence and HCV primary liver transplantation: a case–control study显示文摘 | Josep Martí Sofia De la Serna Gonzalo Crespo Xavier Forns Joana Ferrer Constantino Fondevila Miquel Navasa Josep Fuster Juan Carlos García‐Valdecasas | 2014 | Clin Transplant2014，，7： | 1 |
| 4 | Results of laparoscopic radiofrequency ablation for HCC . Could the location of the tumour influence a complete response to treatment? A single European centre experience显示文摘 | Sofía Serna Ramón Vilana Santiago Sánchez‐Cabús David Calatayud Joana Ferrer Victor Molina Constantino Fondevila Jordi Bruix Josep Fuster Juan‐Carlos García‐Valdecasas | 2015 | HPB2015，，5： | 1 |
| 5 | Integrative Molecular Analysis of Intrahepatic Cholangiocarcinoma Reveals 2 Classes That Have Different Outcomes显示文摘 | Daniela Sia Yujin Hoshida Augusto Villanueva Sasan Roayaie Joana Ferrer Barbara Tabak Judit Peix Manel Sole Victoria Tovar Clara Alsinet Helena Cornella Brandy Klotzle Jian–Bing Fan Christian Cotsoglou Swan N. Thung Josep Fuster Samuel Waxman Juan Carlos | 2013 | Gastroenterology2013，，4： | 1 |
| 6 | The barcelona approach : diagnosis, staging, and treatment of hepatocellular carcinoma显示文摘 | Josep M Llovet Josep Fuster | 2004 | Liver Transpl2004，10，： | 1 |
| 7 | Effects of interleukin-15 on lipid oxidation显示文摘 | Vanessa Almendro Sílvia Busquets Elisabet Ametller Neus Carbó Maite Figueras Gemma Fuster Josep M. Argilés Francisco J. López-Soriano | 2005 | BBA - Molecular and Cell Biology of Lipids2005，，1： | 1 |
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