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| 1 | Colorectal cancer surveillance in inflammatory bowel disease:Practice guidelines and recent developments显示文摘Patients with long-standing inflammatory bowel disease(IBD)involving at least 1/3 of the colon are at increased risk for colorectal cancer(CRC).Advancements in CRC screening and surveillance and improved treatment of IBD has reduced CRC incidence in patients with ulcerative colitis and Crohn’s colitis.Most cases of CRC are thought to arise from dysplasia,and recent evidence suggests that the majority of dysplastic lesions in patients with IBD are visible,in part thanks to advancements in high definition colonoscopy and chromoendoscopy.Recent practice guidelines have supported the use of chromoendoscopy with targeted biopsies of visible lesions rather than traditional random biopsies.Endoscopists are encouraged to endoscopically resect visible dysplasia and only recommend surgery when a complete resection is not possible.New technologies such as virtual chromoendoscopy are emerging as potential tools in CRC screening.Patients with IBD at increased risk for developing CRC should undergo surveillance colonoscopy using new approaches and techniques. | William T Clarke Joseph D Feuerstein | 2019 | World Journal of Gastroenterology2019，25，30： | 23 |
| 2 | 一种房颤风险评分系统的建立(Framingham心脏研究):基于社区的队列研究显示文摘背景房颤导致了发病率和病死率的显著上升。本研究旨在建立一种预测个体罹患房颤绝对风险的风险评分系统,并提供研究人员评价新危险因素的流程。方法作者评估了Framingham心脏研究中于1968年6月至1987年9月间进行了8044次检测的4764例参与者(55%为女性,年龄45~95岁)。此后,参与者被随访至房颤首发,随访期最长达10年。多变量Coxi回归确认出1(1年内罹患房颤的临床危险因素。次级分析纳入了常规超声心动图检测指标(5152例4参与者,7156次检测)对房颤风险进行再分层评估,并评价超声检测指标能否提高风险预测能力。结果4764例参与者中的457例4(10%)罹患房颤。年龄、性别、体重指数、收缩压、降压治疗、PR间期、有临床意义的心脏杂音及心力衰竭与房颤相关,并被纳入了风险评分模型(除体重指数P=0.08外,其余均为P〈0.05),模型的C统计量为0.78(95%CI0.76~0.80)。10年房颤风险随年龄变化:年龄〈65岁的人群中53例(1%)风险高于15%,而〉65岁的人群中为783例(27%)。为提高预测能力而纳入超声检测指标仅使模型C统计量略微增高,由0.78(95%C10.75~0.80)增至0.79(95%CI0.77~0.82:P=0.005)。超声心动图检测指标并不能改善风险再分层评估(P=0.18)。结论基于社区医疗中易得的临床因素建立的风险评分系统,有助于确认社区个体罹患房颤的风险,评估技术或标志物能否改善风险预测,以及针对高危个体采取预防措施。 | Renate B Schnabel Lisa M Sullivan Daniel Levy Michael J Pencina Joseph M Massaro Ralph B D'Agostino Sr Christopher Newton-Cheh Jennifer F Yamamoto Jared W Magnani Thomas M Tadros William B Kannel Thomas J Wang Patrick T Ellinor Philip A Wolf Ramachanclran S Vasan Emelia J Benjamin 黄刚(译) | 2009 | 世界临床医学2009，，9： | 2 |
| 3 | The fusarium wilt resistance locus Fom-2 of melon contains a single resistance gene with complex features显示文摘 | TAREK J JOSEPH J K SHELLY J N CLAUDE E T RALPH A D | 2004 | The Plant Journal2004，39，： | 1 |
| 4 | Self-organizing map for cluster analysis of a breast cancer database显示文摘 | Mia K M Joseph Y L Georgia D T | 2003 | Artificial Intelligence in Medicine2003，27，： | 1 |
| 5 | Apractical guide to ass- essment of ventricular diastolic function using Doppler echocar- diography显示文摘 | Gerald I C Joseph F P James D T | 1996 | JACC1996，27，7： | 1 |
| 6 | Capitalizing China:Institutions and Information Environment of Chinese Listed Firms 显示文摘 | Piotroski Joseph D Wong T J | 2011 | Social Science Electronic2011，47，： | 1 |
| 7 | Platelet activation in acute pulmonary embolism 显示文摘 | Chung T Connor D Joseph J | 2007 | J Thromb Haemost2007，5，5： | 1 |
| 8 | Grafting of methymethacrylate onto cellulose nitrate initiated by benzoyl peroxide 显示文摘 | Sudhakar D Srinivasan K S V Joseph K T | 1981 | Polymer1981，22，4： | 1 |
| 9 | Politieal Incentives to Suppress Negative Information:Evidence from Chinese Listed Finns 显示文摘 | Piotroski Joseph D Wong T J Zhang Tianyu | 2015 | Joumal of Accounting Research2015，53，2： | 1 |
| 10 | NF2 gene analysis distin-guishes hemangiopercytoma from meningioma显示文摘 | Joseph J T Lisle D K Jacoby L B | 1995 | Am J Pathol1995，147，5： | 1 |
| 11 | NF2 gene a- nalysis distinguishes hemangiopericytoma from meningio- ma显示文摘 | Joseph J T Lisle D K Jacohy L B | 1995 | Am J Pathol1995，147，5： | 1 |
| 12 | Serum Uric Acid and Risk of Coronary Heart Disease显示文摘 | Joseph T Moriarity Aaron R Folsom Carlos Iribarren F.Javier Nieto Wayne D Rosamond | 2000 | Annals of Epidemiology2000，，3： | 1 |
| 13 | Direct and indi- rect effects of particulate matter on the cardiovascular system 显示文摘 | NELIN T D ALLAN M JOSEPH A M | 2012 | Toxieol Lett2012，208，： | 1 |
| 14 | Platelet activation in acute pulmonary embolism显示文摘 | Chung T Connor D Joseph J | | 0，，05： | 1 |
| 15 | Rafetto Chronic Venous Insuficiency显示文摘 | Robert T Eberhardt Joseph D | 2005 | Circulafion2005，111，1： | 1 |
| 16 | NF-κB activation and sustained IL-8 gene expression in primary cultures of cystic fibrosis airway epithelial cells stimulated with Pseudomonas aeruginosa显示文摘 | Joseph T Look D Ferkol T | 2005 | Am J Physiol Lung Cell Mol Physiol2005，288，： | 1 |
| 17 | Universal definition of myocar- dial infarction显示文摘 | Kristian T Joseph SA Harvey D | 2007 | J Am Coll Cardiol2007，50，： | 1 |
| 18 | Influence of piperine onthe pharmacokinetics of curcumin in animals and humanvolunteers 显示文摘 | Shoba G Joy D Joseph T | 1989 | Planta Med1989，64，4： | 1 |
| 19 | Platelet activation in acute pulmonary embolism显示文摘 | Chung T Connor D Joseph J | | 0，，05： | 1 |
| 20 | Diagnostic utility and limitations of glutamine synthetase and serum amyloid associated protein immuno- histochemistry in the distinction of focal nodular hyperplasia and telangiectatic hepatic adenoma (abstract)显示文摘 | Joseph NM Jain D Wu T | 2011 | Mod Pathol2011，24，： | 1 |
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