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| 1 | A phase Ⅱ study of gemcitabine and carboplatin combination chemotherapy in gallbladder carcinoma显示文摘BACKGROUND: Patients with carcinoma of the gallbladder have advanced, unresectable tumor at the time of presentation and face a dismal prognosis in the absence of a standard palliative chemotherapy regimen. This study was undertaken to evaluate the efficacy and safety of combined chemotherapy of gemcitabine and carboplatin in 20 patients with advanced gallbladder carcinoma. METHODS: The criteria of eligibility included chemonaive patients with unresectable gallbladder cancer, bidimensionaIly measurable disease, Zubrod’s performance status≤2, and adequate major organ function. The patients received gemcitabine (1000 mg/m^2) on days 1 and 8, and carboplatin (target AUC of 5.0 mg/ml) on day 1, in a 21-day cycle. CT was used for response assessment. RESULTS: In this group of 20 patients with advanced gallbladder carcinoma 6 were men and 14 women, with a median age of 55 years. The stage of the tumor at presentation was IVB in 14 patients (70%), IVA in 3 (15%) and Ⅲ in 3 (15%). Four patients (21%) achieved a complete response, and 3 (15.7%), a partial response; an overall response rate was 36.7%. The median time to progression of the tumor was 33.8 weeks, and 1-year survival rate of the patients was 43.3%. Anemia of WHO grade Ⅲ or Ⅳ was seen in 2 patients (10%) and 1 patient (5%), respectively. Grade Ⅲ neutropenia and thrombocytopenia were observed in 2 patients (10%) and 1 patient (5%), respectively. CONCLUSION: With mild toxicity, combined chemotherapy of gemcitabine and carhoplatin is effective in the treatment of advanced gallbladder carcinoma. | Pramod Kumar Julka Tarun Puri Goura Kishore Rath | 2006 | Hepatobiliary & Pancreatic Diseases International2006，5，1： | 7 |
| 2 | Bipolar radiofrequency ablation of tibialchondroblastomas: A report of three cases显示文摘Chondroblastoma is a rare benign cartilaginous neoplasm of bone. The recurrence rate is high and complications are frequent following open curettage with bone grafting which is the standard treatment forchondroblastomas. We performed radiofrequency ablation in three cases of tibialchondroblastoma using the bipolar system. One patient experienced residual pain for which repeat ablation was performed. No other complications were observed during follow-up. Radiofrequency ablation may offer an effective alternative for the treatment of selected cases of chondroblastoma. The lesion characteristics which are likely to influence treatment outcome and the advantages offered by the bipolar system are discussed. | Prathiba Rajalakshmi Deep N Srivastava Shivanand Gamanagatti Pramod Kumar Julka Sushma Bhatnagar Shishir Rastogi | 2012 | World Journal of Radiology2012，4，7： | 2 |
| 3 | Primary pediatric mid-brain lymphoma:Report of a rare pediatric tumor in a rare location显示文摘Primary central nervous system lymphoma(PCNSL) is a rare disease in pediatric age group. A thirteen-yearold male child presented with complaints of headache for six months, vomiting and diplopia for three days. Magnetic resonance imaging of the brain showed a single lesion of 1.7 cm × 1.6 cm × 1.6 cm in the mid brain and tectum. He underwent a gross total resection of the tumor. The histopathological evaluation revealed B cell high grade non Hodgkin lymphoma. The patient was treated with High dose methotrexate and cranio spinal radiation. The patient was alive without disease 12 mo after completion of treatment. This case highlights importance of keeping PCNSL as differential in brain stem lesions of pediatric patients also. Radiation and chemotherapy remains the most important treatment for such patients. | Rony Benson Supriya Mallick Suvendu Purkait Vaishali Suri K P Haresh Subhash Gupta Dayanand Sharma Pramod Kumar Julka Goura Kishore Rath | 2016 | World Journal of Clinical Cases2016，4，12： | 2 |
| 4 | Evaluation of single photon emission computed tomography (SPECT) using 99Tcm-tetrofosmin as a diagnostic modality for recurrent posterior fossa tumors显示文摘 | Barai S Bandopadhayaya GP Julka PK | 2003 | J Postgrad Med2003，49，4： | 1 |
| 5 | Revisiting the Role of Computerized Tomographic Scan and Cystoscopy for Detecting Bladder Invasion in the Revised FIGO Staging System for Carcinoma of the Uterine Cervix显示文摘 | Daya Nand Sharma Sanjay Thulkar Shikha Goyal Nootan Kumar Shukla Sunesh Kumar Goura Kisor Rath Parmod Kumar Julka Gagan Saini Amit Bahl | 2010 | International Journal of Gynecological Cancer2010，，3： | 1 |
| 6 | Gastrointestinal hemorrhage in hepatocellular carcinoma: management with transhepatic arterioembolization显示文摘 | D. N. Srivastava D. Gandhi P. K. Julka R. K. Tandon | 2000 | Abdominal Imaging2000，，4： | 1 |
| 7 | Agent-based supply chain management ( n ) : A refinery application 显示文摘 | Julka N Karimi I Srinivasan R | 2002 | Computers & Chemical Engineering2002，26，12： | 1 |
| 8 | Response assessment in solid tumours:a comparison of WHO,SWOG and RE- CIST guidelines 显示文摘 | Julka PK Doval DC Gupta S | 2008 | Br J Radiol2008，81，966： | 1 |
| 9 | Thymic neuroendocrine tumour (carcinoid):clinicopathological features of four patients with different presentation显示文摘 | Dutta R Kumar A Julka PK | 2010 | Interact Cardiovasc Thorac Surg2010，11，6： | 1 |
| 10 | Role of gefitinib in patients with recurrent or metastatic cervical carcinoma ineligible or refractory to systemic chemotherapy: first study from Asia显示文摘 | Sharma DN Rath GK Julka PK | 2013 | Int J Gynecol Cancer2013，23，4： | 1 |
| 11 | Cardiovascular effects of ketamine in sick patients: should physicians be concemed?显示文摘 | Lippmarm M Kamwal A Julka IS | 2010 | J Clin Pharmacol2010，50，4： | 1 |
| 12 | Functional outcomes and height restoration for patients with multiple myeloma-related osteolytic vertebral compression fractures treated with kyphoplasty显示文摘 | Julka A Tolhurst SR Srinivasan RC | 2014 | J Spinal Disord Tech2014，27，6： | 1 |
| 13 | Beneficial effects of electrical stimulation on neuropathic symptoms in diabetes patients 显示文摘 | Julka IS Alvaro M Kumar D | 1998 | J Foot Ankle Surg1998，37，3： | 1 |
| 14 | Agent-based supply chain management 1:framework显示文摘 | JULKA N KARIMI I SRINIVASAN R | 2002 | Computers and Chemical Engineering2002，26，12： | 1 |
| 15 | Effect of aluminum on regoinal brain antioxidant defense status in Wistar rats 显示文摘 | Julka D Gill K D | 1996 | Res Exp Med Berl1996，196，3： | 1 |
| 16 | Agent-based supply chain management 2:a refinery applications显示文摘 | JULKA N KARIMI I SRINIVASAN R | 2002 | Computers and Chemical Engineering2002，26，12： | 1 |
| 17 | Evaluation of single-stage adjustable strabismus surgery under conscious sedation显示文摘 | Sharma P Julka A Gedia R | | 0，，02： | 1 |
| 18 | Evaluation of single-stage adjustable strabismussurgeryunder conscious sedation显示文摘 | Sharma P Julka A GadiaR | 2009 | Indian J Ophthalmol2009，57，2： | 1 |
| 19 | Evaluat ion ofsingle-stage adjustable strabismus surgery under conscioussedation显示文摘 | SHARMA P JULKA A GADIA R | 2009 | Indian J Ophthalmol2009，57，2： | 1 |
| 20 | Distribution of aluminum in different brain regions and body organs of rats 显示文摘 | Julka D Vasistha R K Gill K D | 1996 | Trace Elem Res1996，52，： | 1 |
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