|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Management of femoral neck fractures in the young patient: A critical analysis review显示文摘Femoral neck fractures account for nearly half of all hip fractures with the vast majority occurring in elderly patients after simple falls.Currently there may be sufficient evidence to support the routine use of hip replacement surgery for low demand elderly patients in all but non-displaced and valgus impacted femoral neck fractures.However for the physiologically young patients,preservation of the natural hip anatomy and mechanics is a priority in management because of their high functional demands.The biomechanical challenges of femoral neck fixation and the vulnerability of the femoral head blood supply lead to a high incidence of non-union and osteonecrosis of the femoral head after internal fixation of displaced femoral neck fractures.Anatomic reduction and stable internal fixation are essentials in achieving the goals of treatment in this young patient population.Furthermore,other management variables such as surgical timing,the role of capsulotomy and the choice of implant for fixation remaincontroversial.This review will focus both on the demographics and injury profile of the young patient with femoral neck fractures and the current evidence behind the surgical management of these injuries as well as their major secondary complications. | Thierry Pauyo Justin Drager Anthony Albers Edward J Harvey | 2014 | World Journal of Orthopedics2014，5，3： | 70 |
| 2 | Management and prevention of acute and chronic lateral ankle instability in athletic patient populations显示文摘Acute and chronic lateral ankle instability are common in high-demand patient populations. If not managed appropriately, patients may experience recurrent instability, chronic pain, osteochondral lesions of the talus, premature osteoarthritis, and other significantlong-term disability. Certain populations, including young athletes, military personnel and those involved in frequent running, jumping, and cutting motions, are at increased risk. Proposed risk factors include prior ankle sprain, elevated body weight or body mass index, female gender, neuromuscular deficits, postural imbalance, foot/ankle malalignment, and exposure to at-risk athletic activity. Prompt, accurate diagnosis is crucial, and evidence-based, functional rehabilitation regimens have a proven track record in returning active patients to work and sport. When patients fail to improve with physical therapy and external bracing, multiple surgical techniques have been described with reliable results, including both anatomic and nonanatomic reconstructive methods. Anatomic repair of the lateral ligamentous complex remains the gold standard for recurrent ankle instability, and it effectively restores native ankle anatomy and joint kinematics while preserving physiologic ankle and subtalar motion. Further preventative measures may minimize the risk of ankle instability in athletic cohorts, including prophylactic bracing and combined neuromuscular and proprioceptive training programs. These interventions have demonstrated benefit in patients at heightened risk for lateral ankle sprain and allow active cohorts to return to full activity without adversely affecting athletic performance. | Brendan J Mc Criskin Kenneth L Cameron Justin D Orr Brian R Waterman | 2015 | World Journal of Orthopedics2015，6，2： | 20 |
| 3 | 肌萎缩性侧索硬化蛋白激活小胶质细胞NLRP3炎性小体显示文摘小胶质细胞NLRP3炎性小体激活正在成为神经退行性变过程中神经炎症的关键因素。诸如β-淀粉样蛋白和α-突触核蛋白之类的致病性蛋白质聚集体触发小胶质NLRP3激活,从而导致半胱天冬酶-1激活和IL-1β的分泌。在小鼠肌萎缩性侧索硬化症(ALS)的SOD1G93A模型中,半胱天冬酶-1和IL-1β均促进疾病进展,提示小胶质NLRP3在该进程中发挥作用。然而先前的研究表明,SOD1G93A小鼠小胶质细胞不表达NLRP3,SOD1G93A蛋白在小胶质细胞中产生独立于NLRP3的IL-1β。本研究论证了使用Nlrp3-GFP基因敲入小鼠,在SOD1G93A小鼠中小胶质细胞表达NLRP3。本研究显示聚集和可溶性SOD1G93A均可激活小鼠原代小胶质细胞中的炎性小体,导致半胱天冬酶-1和IL-1β裂解,ASC斑点形成以及呈剂量和时间依赖性的IL-1β分泌。重要的是,SOD1G93A无法从缺乏Nlrp3的小胶质细胞或者用特异性NLRP3抑制剂MCC950预处理的小胶质细胞中诱导IL-1β分泌,从而证实NLRP3是介导SOD1诱导的小胶质细胞IL-1β分泌的关键炎症小体复合物。在TDP-43Q331K ALS小鼠模型中也观察到小胶质NLRP3上调,TDP-43野生型和突变蛋白亦可以NLRP3依赖性的方式激活小胶质炎性小体。从机制上讲,本研究确定了活性氧簇和ATP的生成是SOD1G93A介导的NLRP3激活所需的关键事件。总之,本研究的数据表明ALS小胶质细胞表达NLRP3,而病理ALS蛋白激活小胶质NLRP3炎性小体。因此,NLRP3抑制可能是阻止小胶质细胞神经炎症和ALS疾病进展的潜在治疗方法。 | Vandana Deora John D Lee Eduardo AAlbornoz Luke McAlary Cyril J Jagaraj Avril A B Robertson Julie D Atkin Matthew A Cooper Kate Schroder Justin J Yerbury Richard Gordon Trent MWoodruff 杜一星(编译) | 2020 | 神经损伤与功能重建2020，15，9： | 13 |
| 4 | 后循环大血管闭塞性卒中的血管内治疗策略:美国神经介入外科学会(SNIS)标准和指南委员会共识显示文摘后循环卒中大约占所有卒中的20%,但后循环急性大血管闭塞(pc-ELVO)仅占所有急性大血管闭塞性卒中的5%。尽管少见,但pc-ELVO患者往往病情严重,症状也不典型,良好预后率低。如何更好地对这些患者进行管理,是目前临床治疗的难点。近期,美国神经介入外科学会(SNIS)发布了一项关于后循环大血管闭塞性卒中的血管内治疗指南,旨在为pc-ELVO的影像学检查、诊断和血管内治疗技术提供详细的最新指导。 | Yasha Kayan Philip M Meyers Charles J Prestigiacomo Peter Kan Justin F Fraser 王丽娜(翻译) 刘焕(翻译) 贺迎坤(翻译) 邢莹(翻译) 何艳艳(翻译) 李天晓(翻译) 朱良付(翻译) 李钊硕(翻译) | 2019 | 中华介入放射学电子杂志2019，7，4： | 11 |
| 5 | Effect of prophylactic clip placement following endoscopic mucosal resection of large colorectal lesions on delayed polypectomy bleeding: A meta-analysis显示文摘BACKGROUND The role of prophylactic clipping for the prevention of delayed polypectomy bleeding(DPB) remains unclear and conclusions from prior meta-analyses are limited due to the inclusion of variety of resection techniques and polyp sizes.AIM To conduct a meta-analysis on the effect of clipping on DPB following endoscopic mucosal resection(EMR) of colorectal lesions ≥ 20 mm.METHODS We performed a search of PubMed and the Cochrane library for studies comparing the effect of clipping vs no clipping on DPB following endoscopic resection. The Cochran Q test and I^2 were used to test for heterogeneity. Pooling was conducted using a random-effects model.RESULTS Thirteen studies with a total of 7794 polyps were identified, of which data was available on 1701 cases of EMR of lesions ≥ 20 mm. Prophylactic clipping was associated with a lower rate of DPB(1.4%) when compared to no clipping(5.2%)(pooled OR: 0.24, 95%CI: 0.12-0.50, P < 0.001) following EMR of lesions ≥ 20 mm.There was no significant heterogeneity among the studies(I^2 = 0%, P = 0.67).CONLUSION Prophylactic clipping may reduce DPB following EMR of large colorectal lesions.Future trials are needed to further identify risk factors and stratify high risk cases in order to implement a cost-effective preventive strategy. | Fares Ayoub Donevan R Westerveld Justin J Forde Christopher E Forsmark Peter V Draganov Dennis Yang | 2019 | World Journal of Gastroenterology2019，25，18： | 9 |
| 6 | Mortality Risk for Dialysis Patients With Different Levels of Serum Calcium, Phosphorus, and PTH: The Dialysis Outcomes and Practice Patterns Study (DOPPS)显示文摘 | Francesca Tentori Margaret J. Blayney Justin M. Albert Brenda W. Gillespie Peter G. Kerr Jürgen Bommer Eric W. Young Tadao Akizawa Takashi Akiba Ronald L. Pisoni Bruce M. Robinson Friedrich K. Port | 2008 | American Journal of Kidney Diseases2008，，3： | 3 |
| 7 | Prospective Quality Initiative to Maximize Dysphagia Screening Reduces Hospital-Acquired Pneumonia Prevalence in Patients With Stroke显示文摘 | W. Lee Titsworth Justine Abram Amy Fullerton Jeannette Hester Peggy Guin Michael F. Waters J Mocco | 2013 | Stroke2013，，11： | 2 |
| 8 | Fluoroscopically assisted pedicle screw fixation for thoracic and thoracolumbar injuries显示文摘 | John J Carbone M D Justin P | 2003 | SPINE2003，28，1： | 1 |
| 9 | Inter- and intra-organizational knowledge transfer: a meta-ana- lytic review and assessment of its antecedents and eonse- quences显示文摘 | RAYMOND W JUSTIN J P J MARJORIE A L | 2008 | Journal of Management Studies2008，45，4： | 1 |
| 10 | 显示文摘 | Velusamy M Justin Thomas K R Lin J T | 2005 | Org Lett2005，，7： | 1 |
| 11 | The utility of nal and transformational leadership for pre- performance and satisfaction within a theory framework显示文摘 | Vecchio transactlo dicting path-goal R P Justin J E Pearce C L | 2008 | Journal of Occupatio- nal and Organizational Psychology2008，81，1： | 1 |
| 12 | Attentional Changes During Im- plicit Learning: Signal Validity Protects a Target Stimulus From the At- tentional Blink显示文摘 | EVAN J L IRINA M H JUSTIN A H | 2009 | Journal of Experimental Psychology2009，35，2： | 1 |
| 13 | Fluorescence polarization/anisot- ropy in diagnostics and imaging显示文摘 | David M J Justin A R | 2010 | Chemical Reviews2010，110，5： | 1 |
| 14 | Nanostructuring electrodes with carbon nanotubes:A review on electrochemistry and applications for sensing显示文摘 | Justin J G | 2005 | Electrochimica Acta2005，50，15： | 1 |
| 15 | Protection from angiotensinⅡ-induced cardiac hypertrophy and fibrosis by systemic lentiviral delivery of ACE2 in rats显示文摘 | Matthew J Huentelman Justin L Grobe Jorge Vazquez l | 2005 | Experimental Physiology2005，90，5： | 1 |
| 16 | Human Granulocytic Anaplasmosis and Anaplasma Phagocytophilum 显示文摘 | DUMLER J S CHOI K S JUSTIN W G | 2005 | Emerging Infectious Diseases2005，12，11： | 1 |
| 17 | Top management team advice seeking and exploratory innova- tion: the moderating role of TMT heterogeneity显示文摘 | ALEXIEV ALEXANDER S JANSEN JUSTIN J P | 2010 | Jour- nal of Management Studies2010，47，7： | 1 |
| 18 | Use of amino-terminal pro-B-type natriuretic peptide to guide outpatient therapy of patients with chronic left ventricular systolic dysfunction 显示文摘 | JAMES L JANUZZI JR MD SHAFIQ U REHMAN M D ASIM A MOHAMMED M D ANJU BHARDWAJ M D LINDA BARAJAS R N JUSTINE BARAJAS HAN-NA KIM M D MPH AARON L BAGGISH M D RORY B WEINER M D ANNABEL CHEN-TOURNOUX MD JANE E MARSHALL RDCS STEPHANIE A MOORE M D WILLIAM D CARLSON M D GREGORY D LEWIS M D JORDAN SHIN M D DOROTHY SULLIVAN ANP KIMBERLY PARKS D O THOMAS J WANG M D SHAWN A GREGORY M D SHANMUGAM UTHAMALINGAM M D MARC J SEMIGRAN M D | 2011 | J Am Coll Cardiol2011，58，18： | 1 |
| 19 | Temporal contiguity between food ingestion and toxicosis affects the acquisition of food aversions in sheep显示文摘 | Frederick D Provenza John V Nolan Justin J Lynch | 1993 | Applied Animal Behaviour Science1993，38，12： | 1 |
| 20 | The compatible-so- lute-binding protein OpuAC from Bacillus subtilis:ligand binding, site--directed mutagenesis, and crystallographic stud- ies显示文摘 | Sander H J Marina H Justin L | 2008 | Journal of Bacteriology2008，190，16： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员