|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | High-resolution microendoscopy for esophageal cancer screening in China: A cost-effectiveness analysis显示文摘AIM:To study the cost-effectiveness of high-resolution microendoscopy(HRME)in an esophageal squamous cell carcinoma(ESCC)screening program in China.METHODS:A decision analytic Markov model of ESCC was developed.Separate model analyses were conducted for cohorts consisting of an averagerisk population or a high-risk population in China.Hypothetical 50-year-old individuals were followed until age 80 or death.We compared three different strategies for both cohorts:(1)no screening;(2)standard endoscopic screening with Lugol’s iodine staining;and(3)endoscopic screening with Lugol’s iodine staining and an HRME.Model parameters were estimated from the literature as well as from GLOBOCAN,the Cancer Incidence and Mortality Worldwide cancer database.Health states in the model included non-neoplasia,mild dysplasia,moderate dysplasia,high-grade dysplasia,intramucosal carcinoma,operable cancer,inoperable cancer,and death.Separate ESCC incidence transition rates were generated for the average-risk and high-risk populations.Costs in Chinese currency were converted to international dollars(I$)and were adjusted to 2012dollars using the Consumer Price Index.RESULTS:The main outcome measurements for this study were quality-adjusted life years(QALYs)and incremental cost-effectiveness ratio(ICER).For the average-risk population,the HRME screening strategy produced 0.043 more QALYs than the no screening strategy at an additional cost of I$646,resulting in an ICER of I$11808 per QALY gained.Standard endoscopic screening was weakly dominated.Among the high-risk population,when the HRME screening strategy was compared with the standard screening strategy,the ICER was I$8173 per QALY.For both the high-risk and average-risk screening populations,the HRME screening strategy appeared to be the most cost-effective strategy,producing ICERs below the willingness-topay threshold,I$23500 per QALY.One-way sensitivity analysis showed that,for the average-risk population,higher specificity of Lugol’s iodine(>40%)and lower specificity of HRME(<70%)could make Lugol’s iodine screening cost-effective.For the high-risk population,the results of the model were not substantially affected by varying the follow-up rate after Lugol’s iodine screening,Lugol’s iodine test characteristics(sensitivity and specificity),or HRME specificity.CONCLUSION:The incorporation of HRME into an ESCC screening program could be cost-effective in China.Larger studies of HRME performance are needed to confirm these findings. | Chin Hur Sung Eun Choi Chung Yin Kong Gui-Qi Wang Hong Xu Alexandros D Polydorides Li-Yan Xue Katherine E Perzan Angela C Tramontano Rebecca R Richards-Kortum Sharmila Anandasabapathy | 2015 | World Journal of Gastroenterology2015，21，18： | 8 |
| 2 | Determination of para-synephrine and meta-synephrine positional isomers in bitter orange-containing dietary supplements by LC/UV and LC/MS/MS显示文摘 | Jose Santana Katherine E Sharpless Bryant C Nelson | 2008 | Food Chemistry2008，109，： | 1 |
| 3 | Impact of electron acceptor availability on the anaerobic oxidation of methane in coastal freshwater and brackish wetland sediments显示文摘 | Segarra Katherine E A Comerford C Slaughter J | 2013 | Geochimica et Cosmochimica Acta2013，115，： | 1 |
| 4 | The epidemiology of threatened preterm labor :A prospective cohort study显示文摘 | Melissal Mcpheeters William C Miller Katherine E Hartmann | 2005 | Am J Obstet Gynecol2005，192，： | 1 |
| 5 | Oscillating glucose is more deleterious to endothelial function and oxidative stress than mean glucose in normal and type 2 diabetic patients显示文摘 | Antonio C Katherine E Ludovica P | 2008 | Diabetes2008，57，5： | 1 |
| 6 | Transoral Incisionless Fundoplication: 2-year Results from the Prospective Multicenter U.S. Study显示文摘 | Bell Reginald C W Barnes William E Carter Bart J Sewell Robert W Mavrelis Peter G Ihde Glenn M Hoddinott Kevin M Fox Mark A Freeman Katherine D Gunsberger Tanja Hausmann Mark G Dargis David Gill Brian DaCosta Wilson Erik Trad Karim S | 2014 | The American Surgeon2014，，11： | 1 |
| 7 | Site uncertainty,allocation uncertainty,and superfund liability valuation显示文摘 | Katherine C Stephan E S Naomi S S | 1998 | Journal of Accounting and public policy1998，17，： | 1 |
| 8 | Interferon inducible T cell alpha chemoattractant (I-TAC):a novel Non-ELR CXC chemokine with potent activity on activated T cells through selective high afflnity Binding to CXCR3显示文摘 | Katherine E C Christine A S Timothy J P | 1998 | J Exp Med1998，187，12： | 1 |
| 9 | Sea-level rise and coastal forest retreat on the west coast of Florida,USA显示文摘 | KIMBERLYN W KATHERINE C E RICHARD P S | 1999 | Ecology1999，80，6： | 1 |
| 10 | Medication beliefs predict medication adherence in ambulatory patients with decompensated cirrhosis显示文摘AIM To investigate the impact of medication beliefs, illness perceptions and quality of life on medication adherence in people with decompensated cirrhosis.METHODS One hundred adults with decompensated cirrhosis completed a structured questionnaire when they attended for routine outpatient hepatology review. Measures of self-reported medication adherence(Morisky Medication Adherence Scale), beliefs surrounding medications(Beliefs about Medicines Questionnaire), perceptions of illness and medicines(Brief Illness Perception Questionnaire), and quality of life(Chronic Liver Disease Questionnaire) were examined. Clinical data were obtained via patient history and review of medical records. Least absolute shrinkage and selection operator and stepwise backwards regression techniques were used to construct the multivariable logistic regression model. Statistical significance was set at alpha = 0.05.RESULTS Medication adherence was ' High ' in 42 % o f participants, 'Medium' in 37%, and 'Low' in 21%. Compared to patients with 'High' adherence, those with 'Medium' or 'Low' adherence were more likely to report difficulty affording their medications(P < 0.001), lower perception of treatment helpfulness(P = 0.003) and stronger medication concerns relative to medication necessity beliefs(P = 0.003). People with 'Low' adherence also experienced greater symptom burden and poorer quality of life, including more frequent abdominal pain(P = 0.023), shortness of breath(P = 0.030), and emotional disturbances(P = 0.050). Multivariable analysis identified having stronger medication concerns relative to necessity beliefs(Necessity-Concerns Differential ≤ 5, OR = 3.66, 95%CI: 1.18-11.40) and more frequent shortness of breath(shortness of breath score ≤ 3, OR = 3.87,95%CI: 1.22-12.25) as independent predictors of 'Low'adherence.CONCLUSION The association between 'Low' adherence and patients having strong concerns or doubting the necessity or helpfulness of their medications should be explored further given the clinical relevance. | Kelly L Hayward Patricia C Valery Jennifer H Martin Antara Karmakar Preya J Patel Leigh U Horsfall Caroline J Tallis Katherine A Stuart Penny L Wright David D Smith Katharine M Irvine Elizabeth E Powell W Neil Cottrell | 2017 | World Journal of Gastroenterology2017，23，40： | 1 |
| 11 | C30 Stationary phases for the analysis of food by liquid chromatography显示文摘 | L C Sander E Katherine | 2000 | J Chromatogr A2000，880，： | 1 |
| 12 | The inflammatory eytokines: molecular biomarkers for major depressive disorder显示文摘 | CHARLOTTE M KATHERINE E T LEONARD C S | 2015 | Biomarkersin Medicine2015，9，2： | 1 |
| 13 | Cellulase System of a Free-living, Mesophilic Clostridium( Strain C7 ) 显示文摘 | KATHERINE C SUSAN B L PAROLA E C | 1990 | Journal of Bacteriology1990，172，8： | 1 |
| 14 | Determination of ephedrine alkaloids in dietary supplement standard reference materials显示文摘 | Lane C S Katherine E S Mary B S | 2005 | Anal Chem2005，77，： | 1 |
| 15 | Treatment with supplementary argi-nine ,vitamin C and zinc in patients with pressure ulcers : A random-ised controlled trial显示文摘 | Katherine J Bree E Ann C | 2005 | Clini Nutri2005，24，6： | 1 |
| 16 | Malignant esophageal and esophagorespiratory fistula:palliation with polyethylene covered Z-stent显示文摘 | Katherine E M Paul C L | 1997 | Radiology1997，202，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员