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| 1 | Effect of Clostridium butyricum on fecal flora in Helicobacter pylori eradication therapy显示文摘AIM: To investigate the effect of probiotic bacterium,Clostridium butyricum MIYAIRI 588 strain (CBM) on the changes of the fecal flora in Helicobacter pylori(H pylori)treatment.METHODS: Thirty-five patients with gastric or duodenal ulcers positive for Hpylori were randomized either to 1 wk amoxicillin, clarithromycin, lansoprazole (Group 1) or to the same regimen supplemented with CBM 7 dahead of the triple therapy (Group 2). Stool samples were collected before and 2, 4, 7, 15, and 22 d after the starting eradication therapy, and were examined intestinal flora. Patients were required to keep a diary record of their condition. RESULTS: Obligate anaerobes decreased significantly on d 2, 4, 8 and 15 in Group 1. On the other hand, they did not decrease significantly in Group 2. The Escherichiacoli was dominant bacterium in Enterobacteriaceae, butthat was replaced by other species such as Klebsiella and Enterobacter after eradication in Group 1. The change was suppressed in Group 2. Abdominal symptoms were less frequent in Group 2 than in Group 1.CONCLUSION: The combined use of CBM reduced the changes in the intestinal flora and decreased the incidence of gastrointestinal side effects. | Izumi Shimbo Taketo Yamaguchi Takeo Odaka Kenichi Nakajima Akinori Koide Hidehiko Koyama Hiromitsu Saisho | 2005 | World Journal of Gastroenterology2005，11，47： | 18 |
| 2 | Serum type Ⅳ collagen level is predictive for esophageal varices in patients with severe alcoholic disease显示文摘AIM: To determine factors predictive for esophageal varices in severe alcoholic disease (SAD). METHODS: Abdominal ultrasonography (US) was performed on 444 patients suffering from alcoholism. Forty-four patients found to have splenomegaly and/ or withering of the right liver lobe were defined as those with SAD. SAD patients were examined by upper gastrointestinal (UGI) endoscopy for the presence of esophageal varices. The existence of esophageal varices was then related to clinical variables. RESULTS: Twenty-five patients (56.8%) had esophageal varices. A univariate analysis revealed a significant difference in age and type Ⅳ collagen levels between patients with and without esophageal varices. A logistic regression analysis identified type Ⅳ collagen as the only independent variable predictive for esophageal varices (P = 0.017). The area under the curve (AUC) for type Ⅳ collagen as determined by the receiver operating characteristic (ROC) for predicting esophageal varices was 0.78. CONCLUSION: This study suggests that the level of type Ⅳ collagen has a high diagnostic accuracy for the detection of esophageal varices in SAD. | Satoshi Mamori Yasuyuki Searashi Masato Matsushima Kenichi Hashimoto Shinichiro Uetake Hiroshi Matsudaira Shuji Ito Hisato Nakajima Hisao Tajiri | 2008 | World Journal of Gastroenterology2008，14，13： | 4 |
| 3 | Hyperresponsivity to Low-Dose Endotoxin during Progression to Nonalcoholic Steatohepatitis Is Regulated by Leptin-Mediated Signaling显示文摘 | Kento Imajo Koji Fujita Masato Yoneda Yuichi Nozaki Yuji Ogawa Yoshiyasu Shinohara Shingo Kato Hironori Mawatari Wataru Shibata Hiroshi Kitani Kenichi Ikejima Hiroyuki Kirikoshi Noriko Nakajima Satoru Saito Shiro Maeyama Sumio Watanabe Koichiro Wada Atsus | 2012 | Cell Metabolism2012，，1： | 2 |
| 4 | Diagnostic utility of 123 I-BMIPP imaging in patients with Takotsubo cardiomyopathy显示文摘 | Shinro Matsuo Kenichi Nakajima Seigo Kinuya Masakazu Yamagishi | 2013 | Journal of Cardiology2013，，： | 1 |
| 5 | New EAF dust treatment process with the aid of strong magnetic field显示文摘 | SATOSHI ITOH AKIRA TSUBONE KAZUYO MATSUBAE-YOKOYAMA KENICHI NAKAJIMA TETSUYA NAGASAKA | 2008 | ISIJ International2008，48，10： | 1 |
| 6 | Normal values for nuclear cardiology: Japanese databases for myocardial perfusion, fatty acid and sympathetic imaging and left ventricular function显示文摘 | Kenichi Nakajima | 2010 | Annals of Nuclear Medicine2010，，3： | 1 |
| 7 | The validity of multi-center common normal database for identifying myocardial ischemia: Japanese Society of Nuclear Medicine working group database显示文摘 | Kenichi Nakajima Shinro Matsuo Masaya Kawano Naoya Matsumoto Jun Hashimoto Keiichiro Yoshinaga Junichi Taki Koichi Okuda | 2010 | Annals of Nuclear Medicine2010，，2： | 1 |
| 8 | Cardiovascular events in Japanese asymptomatic patients with type 2 diabetes: a 1-year interim report of a J-ACCESS 2 investigation using myocardial perfusion imaging显示文摘 | Kenichi Nakajima Yoshimitsu Yamasaki Hideo Kusuoka Tohru Izumi Atsunori Kashiwagi Ryuzo Kawamori Kazuaki Shimamoto Nobuhiro Yamada Tsunehiko Nishimura | 2009 | European Journal of Nuclear Medicine and Molecular Imaging2009，，12： | 1 |
| 9 | Characterization of Japanese standards for myocardial sympathetic and metabolic imaging in comparison with perfusion imaging显示文摘 | Shinro Matsuo Kenichi Nakajima Shohei Yamashina Kazuyuki Sakata Mitsuru Momose Jun Hashimoto Shinichiro Kumita Masaya Kawano Koichi Okuda | 2009 | Annals of Nuclear Medicine2009，，6： | 1 |
| 10 | Clinical usefulness of novel cardiac MDCT/SPECT fusion image显示文摘 | Shinro Matsuo Kenichi Nakajima Nasima Akhter Hiroshi Wakabayashi Junichi Taki Koichi Okuda Seigo Kinuya | 2009 | Annals of Nuclear Medicine2009，，6： | 1 |
| 11 | Standardization of the heart-to-mediastinum ratio of 123I-labelled-metaiodobenzylguanidine uptake using the dual energy window method: feasibility of correction with different camera–collimator combinations显示文摘 | Shinro Matsuo Kenichi Nakajima Koichi Okuda Masaya Kawano Takehiro Ishikawa Tetsuo Hosoya Junichi Taki Seigo Kinuya | 2009 | European Journal of Nuclear Medicine and Molecular Imaging2009，，4： | 1 |
| 12 | Electrocardiographic Gated ^99mTc-MIBI SPECT for Functional Assessment of Patients After Coronary Artery Bypass Surgery: Comparison of Wall Thickening and Wall Motion Analysis显示文摘 | Junichi Taki Takahiro Higuchi Kenichi Nakajima | 2002 | JNM2002，43，： | 1 |
| 13 | Regional wall thickening in gated myocardial perfusion SPECT in a Japanese population: effect of sex, radiotracer, rotation angles and frame rates显示文摘 | Nasima Akhter Kenichi Nakajima Koichi Okuda Shinro Matsuo Tatsuya Yoneyama Junichi Taki Seigo Kinuya | 2008 | European Journal of Nuclear Medicine and Molecular Imaging2008，，9： | 1 |
| 14 | Prognostic study of risk stratification among Japanese patients with ischemic heart disease using gated myocardial perfusion SPECT: J-ACCESS study显示文摘 | Tsunehiko Nishimura Kenichi Nakajima Hideo Kusuoka Akira Yamashina Shigeyuki Nishimura | 2008 | European Journal of Nuclear Medicine and Molecular Imaging2008，，9： | 1 |
| 15 | Giant Intrahepatic Biliary Cystadenoma in a Male: A Case Report, Immunohistopathological Analysis, and Review of the Literature显示文摘 | Shinsuke Kazama MD Takeyuki Hiramatsu MD Shigeru Kuriyama MD Ken Kuriki MD Ryo Kobayashi MD Naoki Takabayashi MD Kenichi Furukawa MD Masami Kosukegawa MD Hitoshi Nakajima MD Kousuke Hara MD | 2005 | Digestive Diseases and Sciences2005，，7： | 1 |
| 16 | Meningioma: Proliferating Potential and Clinicoradiological Features显示文摘 | Satoshi Nakasu Masayuki Nakajima Kenichi Matsumura Yoko Nakasu Jyoji Handa | 1995 | Neurosurgery1995，，6： | 1 |
| 17 | Substance flow analysis of zinc cycle and current status of electric arc furnace dust management for zinc recovery in Taiwan显示文摘 | Hwong-wen Ma Kazuyo Matsubae Kenichi Nakajima Min-Shing Tsai Kung-Hsien Shao Pi-Cheng Chen Chia-Ho Lee Tetsuya Nagasaka | 2011 | Resources, Conservation & Recycling2011，，1： | 1 |
| 18 | Inter-institution preference-based variability of ejection fraction and volumes using quantitative gated SPECT with 99mTc-tetrofosmin: a multicentre study involving 106 hospitals显示文摘 | Kenichi Nakajima Tsunehiko Nishimura | 2006 | European Journal of Nuclear Medicine and Molecular Imaging2006，，2： | 1 |
| 19 | Dual-radionuclide simultaneous gastric emptying and bile transit study after gastric surgery with double-tract reconstruction显示文摘 | Kenichi Nakajima Masaya Kawano Shinichi Kinami Takashi Fujimura Koichi Miwa Norihisa Tonami | 2005 | Annals of Nuclear Medicine2005，，3： | 1 |
| 20 | Clinical use of nuclear cardiology in the assessment of heart failure显示文摘A nuclear cardiology test is the most commonly performed non-invasive cardiac imaging test in patients with heart failure, and it plays a pivotal role in their assessment and management. Quantitative gated single positron emission computed tomography (QGS) is used to assess quantitatively cardiac volume, left ventricular ejection fraction (LVEF), stroke volume, and cardiac diastolic function. Resting and stress myocardial perfusion imaging, with exercise or pharmacologic stress, plays a fundamental role in distinguishing ischemic from nonischemic etiology of heart failure, and in demonstrating myocardial viability. Diastolic heart failure also termed as heart failure with a preserved LVEF is readily identified by nuclear cardiology techniques and can accurately be estimated by peak filling rate (PFR) and time to PFR. Movement of the left ventricle can also be readily assessed by QGS, with newer techniques such as threedimensional, wall thickening evaluation aiding its assessment. Myocardial perfusion imaging is also commonly used to identify candidates for implantable cardiac defibrillator and cardiac resynchronization therapies. Neurotransmitter imaging using 123 I-metaiodobenzylguanidine offers prognostic information in patients with heart failure. Metabolism and function in the heart are closely related, and energy substrate metabolism is a potential target of medical therapies to improve cardiac function in patients with heart failure. Cardiac metabolic imaging using 123 I-15-(p-iodophenyl)3-R, S-methylpentadecacoic acid is a commonly used tracer in clinical studies to diagnose metabolic heart failure. Nuclear cardiology tests, including neurotransmitter imaging and metabolic imaging, are now easily preformed with new tracers to refine heart failure diagnosis. Nuclear cardiology studies contribute significantly to guiding management decisions for identifying cardiac risk in patients with heart failure. | Shinro Matsuo Kenichi Nakajima Seigo Kinuya | 2010 | World Journal of Cardiology2010，2，10： | 0 |
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