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80篇 您的检索式:作者名="KESSLER D J"
    题名 作者 年代 出处 被引量
1胆固醇酯转移蛋白基因的蛋白质截断型变异体与冠状动脉性心脏病风险的关系显示文摘随机对照试验结果表明,抑制胆固醇酯转运蛋白(cholesteryl ester transfer protein,CETP)的疗法并不能降低冠状动脉性心脏病(coronary heart disease,CHD)的发生风险。研究失败的可能原因包括靶目标无效、靶目标外小分子的不良反应和随机对照设计因素影响等。在编码药物靶点的基因中具有天然存在的遗传变异,以此为基础,人类研究可以深入了解针对基因产物的治疗的潜在功效和安全性。Nomura A Won HH Khera AV Takeuchi F Ito K McCarthy S Emdin CA Klarin D Natarajan P Zekavat SM Gupta N Peloso GM Borecki IB Teslovich TM Asselta R Duga S Merlini PA Correa A Kessler T Wilson JG Bown MJ Hall AS Braund PS Carey DJ Murray MF Kirchner HL Leader JB Lavage DR Manus JN Hartze DN Samani NJ Schunkert H Marrugat J Elosua R McPherson R Farrall M Watkins H Juang JJ Hsiung CA Lin SY Wang JS Tada H Kawashiri MA Inazu A Yamagishi M Katsuya T Nakashima E Nakatochi M Yamamoto K Yokota M Momozawa Y Rotter JI Lander ES Rader DJ Danesh J Ardissino D Gabriel S Willer CJ Abecasis GR Saleheen D Kubo M Kato N Ida Chen YD Dewey FE Kathiresan S 刘莉 叶鹏 2017中华高血压杂志2017,25,9:2
2查看详情显示文摘Regan S P Marozas J A Craxton R S Kelly J H Donaldson W R Jaanimagi P A Jacobs-Perkins D Keck R L Kessler T J Mey-erhofer D D Sangster T C Seka W Smalyuk V A Sknpsky S Zuegel J D 0,,:1
3OMEGA EP high-energy petawatt laser: progress and prospects显示文摘D N Maywar J H Kelly L J Waxer S F B Morse I A Begishev J Bromage C Dorrer J L Edwards L Folnsbee M J Guardalben S D Jacobs R Jungquist T J Kessler R W Kidder B E Kruschwitz S J Loucks J R Marciante R L McCrory D D Meyerhofer A V Okishev J B Oliver G Pien 2008Journal of Physics: Conference Series2008,,3:1
4Shared signals ' alarm calls' from plants increase apparency to herbivores and their enemies in nature显示文摘Halitschke R Stenberg J A Kessler D 2008Ecology Letters2008,11,:1
5Impact of malpractice re- forms on the supply of physician services显示文摘Kessler D P Sage W M Becket D J 2005JAMA2005,293,24:1
6Root effects on the spatial and temporal dynamics of oxygen in sand-based labora- tory-scale constructed biofilters显示文摘MINETT D A COOK P L KESSLER A J 2013Ecological Engineering2013,58,:1
7A persistent oxygen anomaly reveals the fate of spilled methane in the deep Gulf of Mexico显示文摘J D Kessler D L Valentine M C Redmond 2011Science2011,331,6015:1
8Two interferon-induced nuclear factors bind a single promoter element in interferon-stimulated genes 显示文摘Kessler D S Levy D E Darnell J E Jr 1988Proc Natl Acad Sci U S A1988,85,22:1
9Interference by lipids in thedetermination of protein using bicinchoninic acid显示文摘KESSLER R J FANESTIL D D 1986AnalBiochem1986,159,1:1
10Forward osmosis extractors显示文摘C D Moody J O Kessler 1976Desalination1976,18,:1
11Pyruvate-formate-lyase-deactivase and acetyl-CoA reductase activities of Escherichia coli reside on a polymeric protein particle encoded by adhE显示文摘Kessler D Leibrecht I Knappe J 1991FEBS Lett1991,281,9:1
12The effects of competition on variation in the quality and cost of medical care显示文摘Kessler D P Geppert J J 2005Journal of Economics and Management Strategy2005,14,3:1
13Collision frequency of artificial satellites:the creation of a debris belt显示文摘KESSLER D J COUR P B 1978Journal of Geophysical Researcb1978,83,6:1
14Contribution of explosion and future collision fragments to the orbital debris environment显示文摘SU S Y KESSLER D J 1985Advances in Space Research1985,,2:1
15Accentuated osteoclastic response to parathy- roid hormone undermines bone mass acquisition in osteonectin-null mice 显示文摘Machado do Reis L Kessler CB Adams D J 2008Bone2008,43,2:1
16Coming to terms with the terms of risks显示文摘Kraemer H C Kazdin A E Offord D R Kessler R C Jensen P S Kupfer D J 1997Archives of General Psychiatry1997,54,:1
17Fascia patch graft for a digital flexr sheath defect over primary tendon repair in the chicken 显示文摘Kessler FB Epstein M J Lannik D 1986J Hand Surg Am1986,11,2:1
18Collision frequency of ar-tiˉcial satellites: The creation of a debris belt 显示文摘Kessler D J V Cour Palais B G 1978Journalof Geophysical Research: Space Physics (1978{2012)1978,83,6:1
19Fascia patch graft for a digital flexor sheath defect over primary tendon repair in the chicken显示文摘Kessler FB Epstein M J Lannik D 1986J Hand Surg[ Am]1986,11,2:1
20Shared signals' alarm calls' from plants increase apparency to herbivores and their enemies in nature 显示文摘Halitschke R Stenberg J A Kessler D 2008Ecology Letters2008,11,1:1
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