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| 1 | 大气二氧化氮与每日总死亡率、心血管和呼吸系统疾病死亡率的短期关联:398个城市的多中心分析显示文摘目的:采用统一的分析方案,评估全球多个国家/地区的二氧化氮(NO_(2))与总死亡率、心血管和呼吸系统疾病死亡率之间的短期关联。研究设计:采用两阶段的时间序列分析方法、过度离散的广义线性模型和多水平meta分析。研究地点:22个低到高收入国家/地区的398个城市。主要结局指标:1973—2018年逐日总死亡人数(6280万人)、心血管疾病死亡人数(1970万人)和呼吸系统疾病死亡人数(550万人)。结果:平均而言,NO_(2)浓度在滞后1天(前1天)每增加10μg/m^(3),会导致总死亡率、心血管和呼吸系统疾病死亡率分别增加0.46%(95%可信区间0.36%~0.57%)、0.37%(0.22%~0.51%)、0.47%(0.21%~0.72%)。在对共污染物(PM_(10)、PM_(2.5)、臭氧、二氧化硫和一氧化碳)进行调整后,这些关联仍然很稳定。所有3种死因的暴露-反应曲线几乎是线性的,没有明显的阈值。在398个城市中,可归因于高过假定零水平的NO_(2)浓度造成的死亡比例为1.23%(95%可信区间0.96%~1.51%)。结论:这项多中心研究提供了关于NO_(2)短期暴露与总死亡率、心血管和呼吸系统死亡风险之间的独立和线性关联的关键证据,说明通过加强NO_(2)的控制和监管限制标准,可获得人群水平的健康收益。 | 孟夏 刘聪(校) 陈仁杰 郑湃(译) 阚海东(校) Francesco Sera Ana Vicedo-Cabrera Ai Milojevic Maria Guo Yuming Tong Shilu Micheline de Sousa Zanotti Stagliorio Coelh Paulo Hilario Nascimento Saldiva Eric Lavigne Patricia Matus Correa Nicolas Valdes Ortega Samuel Osorio Garcia Jan Kysely Ales Urban Hans Orru Marek Maasikmets Jouni J K Jaakkola Niilo Ryti Veronika Huber Alexandra Schneider Klea Katsouyanni Antonis Analitis Masahiro Hashizume Yasushi Honda Chris Fook Sheng Ng Baltazar Nunes João Paulo Teixeira Iulian Horia Holobaca Simona Fratianni Ho Kim Aurelio Tobias Carmeníniguez Bertil Forsberg ChristoferÅström Martina S Ragettli Yue-Liang Leon Guo Shih-Chun Pan Shanshan Li Michelle L Bell Antonella Zanobetti Joel Schwartz Tangchun Wu Antonio Gasparrini | 2021 | 英国医学杂志中文版2021，24，8： | 7 |
| 2 | Prognostic value of pre-treatment F-18-FDG PET-CT in patients with hepatocellular carcinoma undergoing radioembolization显示文摘AIM To evaluate the value of pre-treatment 18F-FDG PET/CT in patients with HCC following liver radioembolization.METHODS We identified 34 patients with HCC who underwent an FDG PET/CT scan prior to hepatic radioembolization at our institution between 2009 and 2013. Patients wereseen in clinic one month after radioembolization and then at 2-3 mo intervals. We assessed the influence of FDG tumor uptake on outcomes including local liver control(LLC), distant liver control(DLC), time to distant metastases(DM), progression free survival(PFS) and overall survival(OS).RESULTS The majority of patients were males(n = 25, 74%), and had Child Pugh Class A(n = 31, 91%), with a median age of 68 years(46-84 years). FDG-avid disease was found in 19(56%) patients with SUVmax ranging from 3 to 20. Female patients were more likely to have an FDG-avid HCC(P = 0.02). Median follow up of patients following radioembolization was 12 months(1.2-62.8 mo). FDG-avid disease was associated with a decreased 1 year LLC, DLC, DM and PFS(P < 0.05). Using multivariate analysis, FDG avidity predicted for LLC, DLC, and PFS(all P < 0.05).CONCLUSION In this retrospective study, pre-treatment HCC FDGavidity was found to be associated with worse LLC, DLC, and PFS following radioembolization. Larger studies are needed to validate our initial findings to assess the role of F-18-FDG PET/CT scans as biomarker for patients with HCC following radioembolization. | Yazan Abuodeh Arash O Naghavi Kamran A Ahmed Puja S Venkat Youngchul Kim Bela Kis Junsung Choi Benjamin Biebel Jennifer Sweeney Daniel A Anaya Richard Kim Mokenge Malafa Jessica M Frakes Sarah E Hoffe Ghassan El-Haddad | 2016 | World Journal of Gastroenterology2016，22，47： | 3 |
| 3 | A framework infrageneric classification of Carex (Cyperaceae) and its organizing principles显示文摘Phylogenetic studies of Carex L.(Cyperaceae)have consistently demonstrated that most subgenera and sections are para-or polyphyletic.Yet,taxonomists continue to use subgenera and sections in Carex classification.Why?The Global Carex Group(GCG)here takes the position that the historical and continued use of subgenera and sections serves to(i)organize our understanding of lineages in Carex,(ii)create an identification mechanism to break the~2000 species of Carex into manageable groups and stimulate its study,and(iii)provide a framework to recognize morphologically diagnosable lineages within Carex.Unfortunately,the current understanding of phylogenetic relationships in Carex is not yet sufficient for a global reclassification of the genus within a Linnean infrageneric(sectional)framework.Rather than leaving Carex classification in its current state,which is misleading and confusing,we here take the intermediate steps of implementing the recently revised subgeneric classification and using a combination of informally named clades and formally named sections to reflect the current state of our knowledge.This hybrid classification framework is presented in an order corresponding to a linear arrangement of the clades on a ladderized phylogeny,largely based on the recent phylogenies published by the GCG.It organizes Carex into six subgenera,which are,in turn,subdivided into 62 formally named Linnean sections plus 49 informal groups.This framework will serve as a roadmap for research on Carex phylogeny,enabling further development of a complete reclassification by presenting relevant morphological and geographical information on clades where possible and standardizing the use of formal sectional names. | Eric H.Roalson Pedro Jiménez-Mejías Andrew L.Hipp Carmen Benítez-Benítez Leo P.Bruederle Kyong-Sook Chung Marcial Escudero Bruce A.Ford Kerry Ford Sebastian Gebauer Berit Gehrke Marlene Hahn Muhammad Qasim Hayat Mathias H.Hoffmann Xiao-Feng Jin Sangtae Kim Isabel Larridon Étienne Léveillé-Bourret Yi-Fei Lu Modesto Luceño Enrique Maguilla Jose IgnacioMárquez-Corro Santiago Martín-Bravo Tomomi Masaki Mónica Míguez Robert F.C.Naczi Anton A.Reznicek Daniel Spalink Julian R.Starr Uzma Tamara Villaverde Marcia J.Waterway Karen L.Wilson and Shu-Ren Zhang | 2021 | Journal of Systematics and Evolution2021，59，4： | 3 |
| 4 | A comparative study on retrogradation of dee starch gels by DSC, x-ray and a-amylase methods 显示文摘 | KIM J O KIM W S SHIN M S | 1997 | Starch/Starke1997，49，2： | 1 |
| 5 | Systematic design of pore size and functionality in isoreticular MOFs and their application in methane storage显示文摘 | Eddaoudi Mohamed Kim Jaheon Rosi Nathaniel Vodak David Wachter Joseph O'Keeffe Michael Yaghi Omar M | 2002 | Science2002，295，： | 1 |
| 6 | Thiazolidinediones improve insulin sensitivity in adipose tissue and reduce the hyperlipidaemia without affecting the hyperglycaemia in a transgenic model of type 2 diabetes 显示文摘 | Kim H Haluzik M Gavrilova O | 2004 | Diabetologia2004，47，12： | 1 |
| 7 | Efficacy of gmeitabine in ptients with non-small cell lung cancer according to promoter polymorphisms of the ribonueleotide reducume Mi gene显示文摘 | Kim S O Jeong J Y Kim M R | | 0，，10： | 1 |
| 8 | Surface modification of graphite by coke coating for reduction of initial irreversible capacity in lithium secondary batteries显示文摘 | YOON S H KIM H SEUNG M O | 2001 | Journal of Power Sources2001，94，： | 1 |
| 9 | Surface analysis of clinically failed dental implant fixture显示文摘 | CHOE H C HONG K S KO Y M KIM B O | 2006 | J Kor Inst Met & Mater2006，44，： | 1 |
| 10 | Conjugated linoleic acid supplementation reduces adipose tissue by apoptosis and develops lipodystrophy in mice显示文摘 | N Tsuboyama-Kasaoka M Takahashi K Tanemura H Kim T Tange H Okuyama M Kasai S Ikemoto O Ezaki | 2000 | Diabetes2000，，49： | 1 |
| 11 | Thiazolidinediones improve insulin sensitivity in adipose tissue and reduce the hyperlipidaemia without affecting the hyperglycaemia in a transgenic model of type 2diabetes显示文摘 | Kim H Haluzik M Gavrilova O | 2004 | Diabetologia2004，47，12： | 1 |
| 12 | Immunomodulating activity of arabinogataetan and fucoidan in vitro显示文摘 | Choi E M Kim A J Kim Y O | 2005 | Journal of Medicinal Food2005，8，4： | 1 |
| 13 | Anaplastic lymphoma kinase translocation:a predictive biomarker of permetrexed in patients with non-small cell lung cancer 显示文摘 | Lee J O Kim T M Lee S H | 2011 | J Thorac Oncol2011，6，： | 1 |
| 14 | Stability characteristics of Pt1Ni1/C as cathode catalysts in membrane electrode assembly of polymer electrolyte membrane fuel cell显示文摘 | CHO Y H JEON T Y YOO S J LEE K S AHN M KIM O H CHO Y H LIM J W JUNG N YOON W S CHOE H SUNG Y E | 2012 | Electrochim Acta2012，59，： | 1 |
| 15 | Alveolar soft part sarco- ma metastasized to both the skull and the brain 显示文摘 | Shin T H Jung Y J Kim O L Kim M S | 2012 | J Korean Neu- rosurg Soc2012，52，1： | 1 |
| 16 | Analyses on fluid flow and heat transfer inside calandria vessel of CANDU-6 using CFD显示文摘 | KIM M YU S O KIM H J | | 0，，11： | 1 |
| 17 | Physical structure and expression of alkBA encoding alkane hydroxy- lase and rubredoxin reductase from Pseudomonas maltophilia 显示文摘 | Lee N R Hwang M O Jung G H Kim Y S Min K H | 1996 | Biochem Biophys Res Commun1996，218，1： | 1 |
| 18 | Thickness control of colloidal crystals with a substrate dipped at a tilted angle into a colloidal suspension 显示文摘 | Im S H Kim M H Park O O | 2003 | Chem Mater2003，15，9： | 1 |
| 19 | Gas6/Axl signaling activates the phosphatidylinositol 3-kinase/Aktl survival pathway to protect oligodendrocytes from tumor necrosis factor alpha-inducedapoptosis显示文摘 | SHANKAR S L O'GUIN K KIM M | 2006 | J Neurosci2006，，： | 1 |
| 20 | Feature Matching in Omnidirectional Images with a Large Sensor Motion for Map Generation of a Mobile Robot显示文摘 | Lee Y Kim D o Chung M | 2004 | Pattern Recognition Letters2004，25，4： | 1 |
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