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| 1 | Influence of cardiac nerve status on cardiovascular regulation and cardioprotection显示文摘Neural elements of the intrinsic cardiac nervous system transduce sensory inputs from the heart, blood vessels and other organs to ensure adequate cardiac function on a beat-to-beat basis. This inter-organ crosstalk is critical for normal function of the heart and other organs; derangements within the nervous system hierarchy contribute to pathogenesis of organ dysfunction. The role of intact cardiac nerves in development of, as well as protection against, ischemic injury is of current interest since it may involve recruitment of intrinsic cardiac ganglia. For instance, ischemic conditioning, a novel protection strategy against organ injury, and in particular remote conditioning, is likely mediated by activation of neural pathways or by endogenous cytoprotective bloodborne substances that stimulate different signalling pathways. This discovery reinforces the concept that inter-organ communication, and maintenance thereof, is key. As such, greater understanding of mechanisms and elucidation of treatment strategies is imperative to improve clinical outcomes particularly in patients with comorbidities. For instance, autonomic imbalance between sympathetic and parasympathetic nervous system regulation can initiate cardiovascular autonomic neuropathy that compromises cardiac stability and function. Neuromodulation therapies that directly target the intrinsic cardiac nervous system or other elements of the nervous system hierarchy are currently being investigated for treatment of different maladies in animal and human studies. | John G Kingma Denys Simard Jacques R Rouleau | 2017 | World Journal of Cardiology2017，9，6： | 6 |
| 2 | 双侧前庭病诊断标准:Bárány学会前庭疾病分类委员会共识显示文摘Barany学会前庭疾病分类委员会制定了双侧前庭病(bilateral vestibulopathy,BVP)的诊断标准。其诊断需基于病史、床旁查体和实验室检查进行评估。BVP是一类以站立或行走时出现不稳症状、在头部运动或黑暗环境和(或)地面不平时不稳加重为特点的慢性前庭综合征。此外,患者可伴头部或身体运动诱发的视物模糊或振动幻视;在静坐或平躺时通常没有症状。双侧前庭眼反射(vestibulo-ocular reflex,VOR)功能明显下降或缺损是诊断BVP的基础。对于角前庭-眼动反射(angular VOR,aVOR)的检测,可以通过头脉冲试验(head impulse test,HIT)、视频头脉冲试验(video HIT,vHIT)和巩膜搜索线圈技术来评估高频区域的功能,温度试验检测低频区域功能,正弦谐波或阶梯模式的转椅试验评估中频区域功能。BVP诊断标准:双侧水平VOR增益均<0.6(角速度为150°/s^300°/s)和(或)温度试验反应减弱(每一侧冷水和热水刺激诱发出的眼震高峰慢相角速度(slow-phase velocity,SPV)之和<6°/s)和(或)正弦谐波转椅试验(0.1 Hz,Vmax为50°/s)水平VOR增益<0.1,相位超前>68°(时间常数<5 s)。可能的BVP诊断标准为上述典型症状和床旁HIT显示双侧水平半规管病变。以下检查可作为补充检测但目前尚未纳入在诊断标准中:(1)动态视敏度(dynamic visual acuity,DVA)(视力下降≥0.2 LogMAR);(2) Romberg试验阳性(提示前庭或本体感觉系统障碍,因此无特异性);(3)颈性和眼性前庭诱发肌源性电位(vestibular evoked myogenic potentials,VEMP)提示耳石器功能异常。目前对BVP亚型进一步细分的证据尚不充分,很难提出具有临床意义的定义。将来可根据解剖结构和频率特性对BVP的亚型进行分类:如低频或高频VOR范围内单纯半规管功能受损或单纯耳石器功能受损,其中后者较为罕见。双侧前庭病是一个临床综合征,诊断时应考虑其已知的病因(例如耳毒性药物中毒、双侧梅尼埃病、双侧前庭神经鞘瘤)。双侧前庭病还可被称为双侧前庭功能衰减、功能不足、反射消失、功能低下及功能丧失。 | 凌霞(译) 朱扬(译) 王璟(审校) 杨旭(审校) Michael Strupp Ji-Soo Kim Toshihisa Murofushi Dominik Straumann Joanna CJen Sally MRosengren Charles CDella Santina Herman Kingma | 2019 | 神经损伤与功能重建2019，14，12： | 4 |
| 3 | Prolonged QTc Interval and Risk of Sudden Cardiac Death in a Population of Older Adults显示文摘 | Sabine M.J.M. Straus Jan A. Kors Marie L. De Bruin Cornelis S. van der Hooft Albert Hofman Jan Heeringa Jaap W. Deckers J. Herre Kingma Miriam C.J.M. Sturkenboom Bruno H. Ch. Stricker Jacqueline C.M. Witteman | 2006 | Journal of the American College of Cardiology2006，，2： | 4 |
| 4 | 用于检查临床可疑阑尾炎病人的简单MRI方案:138例病人的应用结果和对阑尾切除效果的影响显示文摘评价屏气MRI检查诊断急性阑尾炎的价值。14个月期间,前瞻性应用MRI评估了138例临床可疑阑尾炎病人。采用屏气快速自旋回波T1、T2和T2脂肪抑制序列。记录影像检查结果并分别与随后的临床、放射学和组织病理学随访资料进行相关性分析。计算可疑阑尾炎病人的影像分析结果对医院资源的影响。138例病人中62例经组织病理学证实为阑尾炎。63例经MRI诊断为阑尾炎,1例为假阳性诊断。最终敏感度和特异度分别为100%和99%。余75例中, | L. Cobben I. Groot L. Kingma E. Coerkamp J. Puylaert J. Blickman 李亚军(译) 李威(校) | 2009 | 国际医学放射学杂志2009，32，4： | 4 |
| 5 | Experimental intracerebral mass: description of model,intracranial pressure changes and neuropathology显示文摘 | Kingma T A Mendelow A D Graham D I | 1998 | J Neuropathol Exp Neurol1998，47，： | 2 |
| 6 | Workplace violence in the health sector: a problem of epidemic proportion显示文摘 | Kingma M | 2001 | Int Nurs Rev2001，48，3： | 1 |
| 7 | Ascites due to hypothyroidism 显示文摘 | Wegdam J A Kooistra H M Kingma B J | 1997 | Ned Tijdschr Geneeskd1997，141，36： | 1 |
| 8 | Heat-shock response and limitation of tissue necrosis during occlusion/reperfusion in rabbit hearts显示文摘 | Currie RW Tanguay RM Kingma JG Jr | 1993 | Circulation1993，87，3： | 1 |
| 9 | Contrast- induced nephropathy : pharmacology, pathophysiology and prevention显示文摘 | Geenen RW Kingma HJ van der Molen AJ | 2013 | Insights Imaging2013，4，6： | 1 |
| 10 | Autotrophic growth of thiobacillus acidophilus in the presence of a surface-active agent, Tween-80显示文摘 | Kingma J G Jr Silver M | 1979 | Applied and Environmental Microbiology1979，38，5： | 1 |
| 11 | Hemedynamic and hormonal changes during erythropoietin therapy in hemodialysispatients显示文摘 | Lebel M Kingma I GroseJ H | 1998 | Jam SocNephrol1998，9，1： | 1 |
| 12 | Strain/order parameter coupling in ferroelastic transition in dense SiO2显示文摘 | Hemley R.J Shu J.F Carpenter M.A Hu J.Z Mao H.K Kingma K.J | | 0，，10： | 1 |
| 13 | Influence of taskoriented training content on skilled arm-hand performance in stroke:a systematic review显示文摘 | Timmermans AA Spooren AI Kingma H | 2010 | Neurorehabil Neural Repair2010，24，9： | 1 |
| 14 | In defense of the lung:surfactant protein A and surfactant protein D显示文摘 | KINGMA P S WHITSETT J A | | 0，，03： | 1 |
| 15 | Contrast-induced nephropathy:pharmacology,pathophysiology and prevention显示文摘 | Remy WF Geenen Hylke Jan Kingma | 2013 | Insights Imaging2013，4，： | 1 |
| 16 | Site-directed mutagenesis and oxygen isotope incorporation studies of the nucleophilic aspartate of haloalkane dehalogenase 显示文摘 | Pries F Kingma J Pentenga M van Pouderoyen G Jeronimus-Stratingh CM Bruins AP Janssen DB | 1994 | Biochemistry1994，33，： | 1 |
| 17 | Heat-shock response and limitation of tissue necrosis during occlusion/reperfusian in rabbit heart显示文摘 | Currie RW Tanguay RM Kingma JG | 1993 | Circulation1993，87，3： | 1 |
| 18 | Microstructural obserations of α-quartz amorphization显示文摘 | Kingma K J Meade C Hemley R J Mao H K Veblen D R | | 0，，： | 1 |
| 19 | Myocardial perfusion imaging findings and the role of adenosine in the warm-up angina phenomenon显示文摘 | Bogaty P Kingma JG Guimond J | 2001 | J Am Coll Cardiol2001，37，2： | 1 |
| 20 | Fatal colchicine toxicity显示文摘 | Simmons RJ Kingma DW | 1989 | Am J Med1989，86，： | 1 |
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