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2951篇 您的检索式:作者名="KIRBY"
    题名 作者 年代 出处 被引量
1Ubiquitin modifications显示文摘Kirby N Swatek David Komander 2016Cell Research2016,26,4:77
2河道陡峭指数所反映的祁连山北翼抬升速率的东西差异显示文摘祁连山位于青藏高原东北边缘,其构造抬升速率及其分布特征是理解青藏高原隆升机制的重要线索.近来,河流水力侵蚀模型的研究表明造山带岩石抬升速率是控制河道陡峭指数的主要因素,并且得到了大量的实践证明.利用这一新的方法对祁连山北翼的河流河道进行了分析,尝试从河道纵剖面陡峭指数特征中提取该区域构造抬升信息.结果显示从东到西河道陡峭指数有明显的不同,有东段小,中、西段大的特征.通过对比分析发现,岩性和降水对河道陡峭指数影响不大,也没有证据表明河流负载对其有明显的贡献.河道比降的变化主要是受区域岩石抬升速率差异的影响,河道陡峭指数的分布特征揭示了祁连山北翼抬升速率的分布特征,东段抬升速率较小,中、西段较大,抬升速率最大的位置位于中段榆木山附近区域.胡小飞 潘保田 KIRBY Eirc 李清洋 耿豪鹏 陈吉峰 2010科学通报2010,55,23:38
3Spatial differences in rock uplift rates inferred from channel steepness indices along the northern flank of the Qilian Mountain,northeast Tibetan Plateau显示文摘The rate and distribution of deformation along the Qilian Mountain,on the northeastern Tibetan Plateau,is needed to understand the evolution of high topography associated with the plateau.Recently,a number of empirical studies have provided support for the contention,common to most models of fluvial incision,that rock uplift rate exerts a first-order control on the gradient of longitudinal river profiles.Along the northern Qilian Mountain,this method is used to extract information about the spatial patterns of differential rock uplift.Analysis of the longitudinal profiles of bedrock channels reveals systematic differences in the channel steepness index along the trend of the frontal ranges.Local comparisons of channel steepness reveal that lithology and precipitation have limited influence on channel steepness.Similarly,there is little evidence suggesting that channel steepness is influenced by differences in the sediment loads.We argue that the distribution of channel steepness in the Qilian Mountain is mostly the result of differential rates of rock uplift.Thus,channel steepness indices reveal a lower rock uplift rate in the eastern portion of the Qilian Mountain and a higher rate in the middle and west.The highest rates appear to occur in the middle-west portions of the range,just to the west of the Yumu Shan.HU XlaoFei PAN BaoTian KIRBY Eric LI QingYang GENG HaoPeng CHEN JiFeng 2010Chinese Science Bulletin2010,55,27:35
4The current status of robot-assisted radical prostatectomy显示文摘帮助机器人的激进的前列腺切除术(RARP ) 是为局部性的前列腺癌症的治疗的一种很快演变的技术。在美国,超过 65% 激进的前列腺切除术是帮助机器人的,尽管在欧洲和世界的其余部分的这种技术的接受有点更慢。这篇文章关于 oncological,克制和力量结果鈥搕h e 在 RARP 上考察当前的文学所谓的“三连胜”。初步的数据看起来证明与减少的血损失,在开的前列腺切除术上的 RARP 的一个优点减少了疼痛,早动员,更短的医院停留和更低的边缘评价。大多数研究与 RARP 显示出好手术后的克制和力量;然而,这需要在在文学可得到的使随机化的数据的少量的上下文被看。没有权威的证据证明超越标准 laparoscopy 的一个优点,而是这种技术在 5 年以内与 laparoscopy 到达了同等值的事实是令人鼓舞的。最后,发展单个港口的机器的前列腺切除术,指导激光的机器人学,没有导管的前列腺切除术和指导图象的机器人学的技术被讨论。Prokar Dasgupta Roger S. Kirby 2009Asian Journal of Andrology2009,11,1:15
5Power Grid Islands Service Restoration Based on Cloud Computing显示文摘提出了一种基于云计算思想的电网恢复重构方法,利用网络中大量的分布式计算资源加速求取孤岛间网络恢复重构的最优解。利用电力系统分层分布式体系结构将含有多个微网的复杂配电网络视为不同的子云计算区,每个子云计算区根据自身情况将重构的服务请求分解为多个可独立处理的计算块并提交分布的计算节点进行并行处理和结果取优。相关联子云计算区之间可通信以协调不同区域间的负荷转供,最终实现故障恢复重构的目标。算例分析结果验证了该方法的有效性。ZHANG Hao HE Jinghan YIN Hang BO Zhiqian B Kirby 2011中国电机工程学报2011,31,34:14
6前庭康复网络干预对老年慢性头晕患者的效果:一项英国社区医疗机构开展的随机对照试验显示文摘目的前庭康复治疗对由前庭功能障碍所致的眩晕来说比较有效,但迄今为止这种康复治疗的开展还较少。本研究旨在探讨前庭康复网络干预项目在社区老年慢性头晕患者中的效果。方法本项为单中心、单盲的随机对照试验,在英格兰南部54家社区医疗机构开展。研究对象为来自这些机构的年龄≥50岁、患有眩晕并头部运动眩晕加重的患者。患者被随机分为干预组和普通治疗组。干预组给予前庭康复网络干预[平衡训练(患者通过网络学习前庭康复训练及认知行为管理策略),详细内容见http://gffzz647ebb38d6614268sn9kwocvbxbnq6n5w.ffgz.tsg.suse.edu.cn],普通治疗组给予普通全科治疗。在干预前、干预3个月及6个月后,采用简明眩晕症状量表(VSS-SF)对患者的眩晕程度进行调查。干预效果的主要评估指标为干预6个月后的VSS-SF分数。结果共纳入296例患者,其中66%为女性,中位年龄为67岁。250例(84%)患者在干预3个月后完成了VSS-SF测评,230例(78%)患者在干预6个月后完成了VSS-SF测评。干预3个月后,干预组VSS-SF分数比普通治疗组低2.75分[95%CI(1.39,4.12),P<0.001];干预组眩晕残障程度分数比普通治疗组低6.15分[95%CI(2.81,9.49),P<0.001]。干预6个月后,干预组VSS-SF分数比普通治疗组低2.26分[95%CI(0.39,4.12),P=0.020];干预组眩晕残障程度分数比普通治疗组低5.58分[95%CI(1.19,10.0),P=0.010]。结论在没有临床支持的情况下,前庭康复网络干预可使社区老年慢性头晕患者眩晕及眩晕残障程度有所降低。这种康复治疗可在社区医疗机构中广泛应用。GERAGHTY A W A ESSERY R KIRBY S 本刊编辑部 2017中国全科医学2017,20,28:10
7后现代主义的死亡及余波显示文摘尽管学校的课堂依旧把后现代主义当做某种健在的事物向学生讲述,但我们只需要把目光稍稍转向学术圈以外的那些当下的文化生产,便可以让人信服地宣布后现代主义已然寿终正寝。伪现代主义是后现代主义之后的新文化主导。在新技术的促进下,伪现代主义让文化产品的接收者以前所未有的姿态加入到文化生产过程中。乐观主义者或许会将其视为文化的民主化,悲观主义者却会指出由此产生的那些文化产品中让人无法忍受的庸俗和空洞。与现代主义的焦虑症和后现代主义的自恋症不同,伪现代主义的病理特征是自闭症,而它的典型情感特征则是无知、狂热和恍惚。Alan Kirby 陈后亮 2012文化艺术研究2012,5,1:7
8Intrinsic control of axon regeneration显示文摘Spinal cord injury disrupts the connections between the brain and spinal cord, often resulting in the loss of sensory and motor function below the lesion site. The most important reason for such permanent functional deficits is the failure of injured axons to regenerate after injury. In principle, the functional recovery could be achieved by two forms of axonal regrowth: the regeneration of lesioned axons which will reconnect with their original targets and the sprouting of spared axons that form new circuits and compensate for the lost function. Our recent studies reveal the activity of the mammalian target of rapamycin (mTOR) pathway, a major regulator of new protein synthesis, as a critical determinant of axon regrowth in the adult retinal ganglion neurons[1]. In this review, I summarize current understanding of the cellular and molecular mechanisms that control the intrinsic regenerative ability of mature neurons.Zhigang He F.M. Kirby Neurobiology Center, Children’s Hospital, and Department of Neurology, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA. 2010The Journal of Biomedical Research2010,24,1:6
9Experimental and Modeling Study of Forest Fire Effect on Soil Thermal Conductivity显示文摘An understanding of soil thermal conductivity after a wildfire or controlled burn is important to land management and post-fire recovery efforts. Although soil thermal conductivity has been well studied for non-fire heated soils, comprehensive data that evaluate the long-term effect of extreme heating from a fire on the soil thermal conductivity are limited. The purpose of this study was to evaluate the long-term impact of fire on the effective thermal conductivity of soils by directly comparing fire-heated and no-fire control soils through a series of laboratory studies. The thermal conductivity was measured for ten soil samples from two sites within the Manitou Experimental Forest, Colorado, USA, for a range of water contents from saturation to the residual degree of saturation. The thermal conductivity measured was compared with independent estimates made using three empirical models from literature, including the Campbell et al.(1994), Cté and Konrad(2005), and Massman et al.(2008) models. Results demonstrate that for the test soils studied, the thermal conductivity of the fire-heated soils was slightly lower than that of the control soils for all observed water contents.Modeling results show that the Campbell et al.(1994) model gave the best agreement over the full range of water contents when proper fitting parameters were employed. Further studies are needed to evaluate the significance of including the influence of fire burn on the thermal properties of soils in modeling studies.Kathleen M.SMITS Elizabeth KIRBY William J.MASSMAN Larry Scott BAGGETT 2016Pedosphere2016,26,4:5
10Utility of tissue microarrays for profiling prognostic biomarkers in clinically localized prostate cancer: the expression of BCL-2, E-cadherin, Ki-67 and p53 as predictors of biochemical failure after radical prostatectomy with nested control for clinical and pathological risk factors显示文摘痊愈不能与经历激进的治疗的临床上局部性的前列腺癌症为所有人被保证。如果他们能改进秘密变形疾病的预言,分子的标记将是无价的。这研究被执行在激进的前列腺切除术标本调查 BCL-2, Ki-67, p53 和 E-cadherin 的表示。我们寻求了估计他们的能力在一个特定的治疗学的背景预言早生物化学的恶化。包括 41 案例对的 82 个病人为病理学的舞台,格利森等级和外科手术前的前列腺特定的抗原(PSA ) 被匹配集中。在每对的一个病人有生物化学的复发(在 2 年外科以内定义为 PSA 0.2 ng mL-1 ) 并且其它没有疾病生物化学地留下了(至少 3 年在外科以后定义同样无法发现的 PSA ) 。Immunohistochemical 分析被执行在四上估计标记表示复制从每个激进的前列腺切除术标本与良性、恶意的织物构造的织物 microarrays。Ki-67, p53 和 BCL-2,然而并非 E-cadherin,显著地在前列腺腺癌的 upregulated 与良性的前列腺织物相比(P < 0.01 ) 。然而,当比较与没有生物化学的复发的病人一起开发了早生物化学的恶化的病人时,在任何标记的表示的重要差别都没被观察。这研究证明 p53, BCL-2 和 Ki-67 的那表情与良性的前列腺织物相比是在临床上局部性的前列腺癌症的 upregulated,没有在 E-cadherin 表示的改变。Biomarker upregulation 没在激进的前列腺切除术以后为生物化学的复发有预示的价值,甚至在考虑病理学的舞台,整个瘤格利森等级和外科手术前的浆液 PSA 水平以后。Joseph Nariculam Alex Freeman Simon Bott Phillipa Munson Noriko Cable Nicola Brookman-Amissah Magali Williamson Roger S. Kirby John Masters Mark Feneley 2009Asian Journal of Andrology2009,11,1:5
11现代电力系统集成后备保护方案显示文摘后备保护不可或缺,特别作为相邻设备的远后备保护功能尤为重要。由于距离保护仅仅依赖本地信息构成,容易实现且性能稳定,因此,所有高压输电线路都把距离保护作为后备保护。遗憾的是,后备保护在大停电过程中所起的作用是消极的,可以说它导致了电网连锁跳闸。因此,有必要重新认识后备保护的作用及其构成方式。提出了一种集成后备保护方案,它把同一个变电站所有被保护设备的后备保护集成在一个装置或者系统中,而所有设备的保护只包含主保护功能。这样的方案有利于构成性能完善的后备保护方案,也可以有效减小大停电的范围。董新洲 曹润彬 崔柳 王宾 施慎行 Dominik Bak Brian Kirby 杨霞 2014电力系统保护与控制2014,42,5:4
12自然杀伤细胞和T淋巴细胞在银屑病发病中作用的研究显示文摘用免疫组化法检侧10例银屑病患者皮损、皮损周围外观正常皮肤和正常对照组自然杀伤细胞(NK细胞)、T细胞表面抗原的表达。结果表明:患者皮损处真皮乳头NK细胞表面抗原CD16、CD56、CD57、CD94、CD158a,T细胞表面抗原CD2、CD3、CD4、CD8和皮肤白细胞相关抗原(CLA)阳性表达的细胞数,较皮损周围外观正常皮肤和正常对照组明显增多(P<0.05或<0.01)。作者认为:T细胞、NK细胞共同参入银屑病的发病,并分析了二者之间相互关系。王飞 Griffiths CEM Kirby B Cameron AL 2002临床皮肤科杂志2002,31,8:4
13Technical advances in laboratory diagnosis of fungal infection显示文摘Qinfang Qian James E. Kirby 2010微生物与感染2010,5,1:4
14Serum and urinary markers of skeletal muscle tissue damage after weight lifting exercise显示文摘G. L. Paul J. P. DeLany J. T. Snook J. G. Seifert T. E. Kirby 1989European Journal of Applied Physiology and Occupational Physiology1989,,:3
15Detection of Circulating Pancreas Epithelial Cells in Patients with Pancreatic Cystic Lesions显示文摘Andrew D. Rhim Fredrik I. Thege Steven M. Santana Timothy B. Lannin Trisha N. Saha Shannon Tsai Lara R. Maggs Michael L. Kochman Gregory G. Ginsberg John G. Lieb Vinay Chandrasekhara Jeffrey A. Drebin Nuzhat Ahmad Yu- Xiao Yang Brian J. Kirby Ben Z. Stang 2013Gastroenterology2013,,:3
16Volumetric parameterization and trivariate B-spline fitting using harmonic functions显示文摘T. Martin E. Cohen R.M. Kirby 2008Computer Aided Geometric Design2008,,6:2
17Sofosbuvir and Ribavirin for Treatment of Compensated Recurrent Hepatitis C Virus Infection After Liver Transplantation显示文摘Michael Charlton Edward Gane Michael P. Manns Robert S. Brown Michael P. Curry Paul Y. Kwo Robert J. Fontana Richard Gilroy Lewis Teperman Andrew J. Muir John G. McHutchison William T. Symonds Diana Brainard Brian Kirby Hadas Dvory-Sobol Jill Denning Sara 2014Gastroenterology2014,,:2
18Deep drawing of pressure vessel end closure:finite element simulation and validation显示文摘Kirby DS Wild PM 2000Journal of Materials Processing Technology2000,103,2:2
19Molecular microbial ecology of lignocellulose mobilisation as a carbon source in mine drainage wastewater treatment显示文摘Clarke AM Kirby R Rose PD 2007中国生物学文摘2007,21,6:2
20Serum and urinary markers of skeletal muscle tissue damage after weight lifting exercise显示文摘G. L. Paul J. P. DeLany J. T. Snook J. G. Seifert T. E. Kirby 1989European Journal of Applied Physiology and Occupational Physiology1989,,7:2
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