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| 1 | Antioxidative effect of melatonin, ascorbic acid and N-acetylcysteine on caerulein-induced pancreatitis and associated liver injury in rats显示文摘瞄准:在老鼠在导致 caerulein 的胰腺炎和联系肝损伤上处于导致胰腺炎的肝的损坏和象 melatonin,抗坏血酸和 N 乙酰半胱氨酸那样的抗氧化剂代理人的效果调查氧化损害的角色。方法:38 只女 Wistar 老鼠被使用。尖锐胰腺炎(AP ) 被 caerulein 的二 i.p 注射在 2-h 间隔导致(在 100 microg/kg b.wt 的全部的剂量) 。另外的二个组收到了另外的 melatonin (20 mg/kg b.wt ) 或包含 L (+) 维生素酸(14.3 mg/kb.wt.) 和 N 乙酰半胱氨酸(181 mg/kg b.wt ) 的抗氧化剂混合物立即在 caerulein 的每注射前的 i.p。老鼠被斩首杀头 12 h 在 caerulein 的最后注射以后牺牲。胰腺、肝的氧化压力标记被变化在在织物抗氧化剂酶层次,过氧化氢酶(猫) 和谷胱甘肽过氧化物酶(GPx ) 作为 malondialdehyde (MDA ) 和变化测量的类脂化合物过氧化物的数量评估。组织病理学说的检查用获得系统被执行。结果:肝的房间退化,细胞内部的空泡形成,脉管的拥挤,正弦曲线膨胀和炎性浸润的度显示出在 caerulein 和 caerulein + melatonin 之间的有效差量(P = 0.001 ) ,并且 careulein 和 caerulein + L (+) 维生素酸 +N 乙酰半胱氨酸组(P = 0.002 ) 。ciner 房间退化,胰腺的浮肿,细胞内部的空泡形成和炎性浸润的度显示出在 caerulein 和 caerulein + melatonin 之间的有效差量(P = 0.004 ) ,并且 careulein 和 caerulein + L (+) 维生素酸 +N 乙酰半胱氨酸组(P = 0.002 ) 。 导致Caerulein 胰腺并且肝损坏伴有织物 MDA 层次的重要增加( P = 0.01 , P = 0.003 ,分别地)而在猫的重要减少( P = 0.002 , P = 0.003 ,分别地)并且 GPx 活动( P = 0.002 , P = 0.03 ,分别地)。Melatonin 和 L (+) 维生素 acid+N 乙酰半胱氨酸管理显著地减少了在胰的 MDA 层次(P=0.03, P=0.002,分别地) 并且肝(P = 0.007, P = 0.01,分别地) 。这些代理人的管理增加了胰腺、肝的猫和 GPx 活动。Melatonin 显著地增加了胰腺、肝的猫(P = 0.002, P = 0.001,分别地) 并且 GPx 活动(P = 0.002, P = 0.001 ) 。另外, L (+) 维生素酸 +N 乙酰半胱氨酸显著地增加了胰腺的 GPx (P = 0.002 ) 并且肝的猫和 GPx 活动(P = 0.001, P = 0.007,分别地).CONCLUSION:氧化损害不仅在 AP 的致病而且处于导致胰腺炎的肝的损坏起一个重要作用。抗氧化剂代理人象 melatonin 和抗坏血酸 +N 乙酰半胱氨酸那样,能够限制经由恢复织物抗氧化剂酶活动在 AP 期间生产的胰腺、肝的损坏。 | Mukaddes E■refoglu Mehmet Gül Burhan Ate■ Kadir Batoglu Mukadder Ay■e Selimoglu | 2006 | World Journal of Gastroenterology2006，12，2： | 29 |
| 2 | Hepatitis B-related events in autologous hematopoietic stem cell transplantation recipients显示文摘AIM: To investigate the frequency of occult hepatitis B, the clinical course of hepatitis B virus (HBV) reactivation and reverse seroconversion and associated risk factors in autologous hematopoietic stem cell transplantation (HSCT) recipients. METHODS: This study was conducted in 90 patients undergoing autologous HSCT. Occult HBV infection was investigated by HBV-DNA analysis prior to transplantation, while HBV serology and liver function tests were screened prior to and serially after transplantation. HBV-related events including reverse seroconversion and reactivation were recorded in all patients. RESULTS: None of the patients had occult HBV prior to transplantation. Six (6.7%) patients were positivefor HBV surface antigen (HBsAg) prior to transplantation and received lamivudine prophylaxis; they did not develop HBV reactivation after transplantation. Clinical HBV infection emerged in three patients after transplantation who had negative HBV-DNA prior to HSCT. Two of these three patients had HBV reactivation while one patient developed acute hepatitis B. Three patients had anti-HBc as the sole hepatitis B-related antibody prior to transplantation, two of whom developed hepatitis B reactivation while none of the patients with antibody to HBV surface antigen (anti-HBs) did so. The 14 anti-HBs-and/or anti-HBc-positive patients among the 90 HSCT recipients experienced either persistent (8 patients) or transient (6 patients) disappearance of anti-HBs and/or anti-HBc. HBsAg seroconversion and clinical hepatitis did not develop in these patients. Female gender and multiple myeloma emerged as risk factors for loss of antibody in regression analysis (P < 0.05). CONCLUSION: Anti-HBc as the sole HBV marker seems to be a risk factor for reactivation after autologous HSCT. Lamivudine prophylaxis in HbsAg-positive patients continues to be effective. | zcan eneli Zübeyde Nur zkurt Kadir Acar Seyyal Rota Sahika Zeynep Aki Zeynep Arzu Yegin Münci Yagci Seren zenirler Gülsan Türkz Sucak | 2010 | World Journal of Gastroenterology2010，16，14： | 3 |
| 3 | Bacterial ferritin contains 24 hame groups显示文摘 | KADIR F H A MOORE G R | 1990 | F E B S Lett1990，271，： | 1 |
| 4 | Remifentanil with thiopental for tracheal intubation without muscle relaxants 显示文摘 | Durmus M Ender G Kadir BA | 2003 | Anesth Analg2003，96，5： | 1 |
| 5 | Effect of diesel–microalgae biodiesel–butanol blends on performance and emissions of diesel engine显示文摘 | G?khan Tüccar Tayfun ?zgür Kadir Ayd?n | 2014 | Fuel2014，，： | 1 |
| 6 | Fractal geometry of the Sumatra active fault system and its geodynamical implications 显示文摘 | SUKMONO S ZEN M T KADIR W G A | 1996 | Journal of Geodynamics1996，22，12： | 1 |
| 7 | Fractal geometry of the Sumatra active fault system and its geodynamical implications显示文摘 | Sigit Sukmono Zen M T Kadir W G A | 1996 | Geodynamics1996，22，： | 1 |
| 8 | Remifentanil withthiopental for tracheal intubation without muscle relaxants显示文摘 | Durmus M Ender G Kadir BA | 2003 | Anesth Analg2003，96，5： | 1 |
| 9 | Automatic Discovery and Composition of Semantic Web Services Using Al Planning and Web Service Modeling Ontology显示文摘 | Tabatabaei S G H Kadir W M N Ibrahim S | | 0，，01： | 1 |
| 10 | Helicobacter pylori Stool Antigen Test: Results of a Prospective Study显示文摘 | Soykan Arikan Ahmet Kocakusak Gül Barut G?nül Sengoz Ahmet F. Yucel Kadir Gokturk | 2004 | Surgery Today2004，，4： | 1 |
| 11 | Remifentanil with thiopental for tracheal intubation without muscle relaxants 显示文摘 | DURMUS M ENDER G KADIR B A | 2003 | Anesth Analg2003，96，5： | 1 |
| 12 | Continuous compartment pressure monitoring for tibia fractures:does it influence outcome显示文摘 | Harris I A Kadir A Donald G | | 0，，06： | 1 |
| 13 | Endophytie microorganisms as potential growth promoters of banana显示文摘 | TING S A MEON S KADIR J RADU S SINGH G | 2008 | Biocontrol2008，，53： | 1 |
| 14 | Rapid deposition of triangular silver nanoplates on planar surfaces:Application to metal-enhanced fluorescence显示文摘 | KADIR A JOSEPH R L CHRIS D G | 2005 | J Phys Chem B2005，109，13： | 1 |
| 15 | Hepatitis B virus vaccine in lymphoprolifera-tive disorders:a prospective randomized study evalutating the efficacy of granulocyte-macrophage colony stimulating factor as a vaccine adjuvant显示文摘 | Kadir Gülsan | 2007 | European Journal of Haematology2007，79，4： | 1 |
| 16 | Remifentanil with thiopental for tracheal intubation without muscle relaxants 显示文摘 | Durmus M Ender G Kadir BA | 2003 | Anesth Analg2003，96，5： | 1 |
| 17 | Frac- tal geometry of the sumatra active fault system and its geodynamical implications 显示文摘 | SUKMONO S ZEN M T KADIR W G A | 1996 | Journal of Geodynam- ics1996，22，12： | 1 |
| 18 | Fractal Geometry of the Sumatra Active fault System and Its Geodynamical Implications显示文摘 | Sigit Sukmono Zen M T Kadir W G A | 1996 | Geodynamics1996，22，1： | 1 |
| 19 | Ureteroscopic treatment of ureteral lithiasis with pneumatic lithotripsy: analysis of 287 procedures in a public hospital显示文摘 | Kadir Ceylan Orhan Sünbül Adem ?ahin Mustafa Güne? | 2005 | Urological Research2005，，6： | 1 |
| 20 | Pathways of auxin transport in the intact pea seedling 显示文摘 | MORRIS D A KADIR G | 1972 | Planta1972，107，： | 1 |
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