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7篇 您的检索式：作者名="Kageaki"

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		题名	作者	年代	出处	被引量
	1	Activity and bioavailability of tepotinib for leptomeningeal metastasis of NSCLC with MET exon 14 skipping mutation显示文摘Tepotinib is a key drug for cancer patients with mesenchymal-epithelial transition receptor tyrosine kinase proto-oncogene(MET)exon 14 skipping mutation.However,its bioavailability in the cerebrospinal fluid(CSF)in humans has not been fully elucidated.Moreover,information about the efficacy of tepotinib in patients with leptomeningeal metastasis is limited.Here,we present the case of a 56-year-old man who was diagnosed with lung adenocarcinoma with MET exon 14 skipping mutation.He was urgently hospitalized due to leptomeningeal metastasis.We administered tepotinib 500 mg/day as the second-line therapy and observed improvement in leptomeningeal metastasis and performance status.The tepotinib concentrations reached 1,648 ng/mL in the plasma and 30.6 ng/mL in the CSF,with a penetration rate(CSF/plasma)of 1.83%.These demonstrate tepotinib could achieve a high rate of central nervous system transition and could be effective against leptomeningeal metastasis.	Hisashi Tanaka Kageaki Taima Tomonori Makiguchi Junichi Nakagawa Takenori Niioka Sadatomo Tasaka	2021	Cancer Communications2021，41，1：	4
	2	Diagnostic relevance of overexpressed Nanog gene in early lung cancers显示文摘	Shinya Nirasawa Daisuke Kobayashi Naoki Tsuji Kageaki Kuribayashi Naoki Watanabe	2009	Oncology Reports2009，，3：	1
	3	SALL4 is essential for cancer cell proliferation and is overexpressedat early clinical stages in breast cancer显示文摘	Daisuke Kobayashi Kageaki Kuribayshi Maki Tanaka Naoki Watanabe	2011	International Journal of Oncology2011，，4：	1
	4	Overexpression of SALL4 in lung cancer and its importance in cell proliferation显示文摘	Daisuke Kobayashi Kageaki Kuribayashi Maki Tanaka Naoki Watanabe	2011	Oncology Reports2011，，4：	1
	5	SALL4 is essential for cancer cell proliferation and is overexpressedat early clinical stages in breast cancer显示文摘	Daisuke Kobayashi Kageaki Kuribayshi Maki Tanaka Naoki Watanabe	2011	International Journal of Oncology2011，，4：	1
	6	Overexpression of SALL4 in lung cancer and its importance in cell proliferation显示文摘	Daisuke Kobayashi Kageaki Kuribayashi Maki Tanaka Naoki Watanabe	2011	Oncology Reports2011，，4：	1
	7	Diagnostic relevance of overexpressed Nanog gene in early lung cancers显示文摘	Shinya Nirasawa Daisuke Kobayashi Naoki Tsuji Kageaki Kuribayashi Naoki Watanabe	2009	Oncology Reports2009，，3：	1

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