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| 1 | 积极坐姿对躯体运动的影响(英文)显示文摘背景:久坐极易导致腰痛。本研究旨在确定积极坐姿是否会增加躯体运动。方法:15名健康女性志愿者分别在气垫、稳定球和硬面这三种不同材质的坐具上坐30分钟。用Vicon运动捕捉系统检测躯干运动,用两块AMTI力板收集两脚的压力中心。结果:躯干中心质量的平均速度随坐具表面柔软度增加而明显增加。受试者坐于稳定球上时两脚前后方向上的压力中心明显不同于坐在气垫和硬面椅上。结论:积极坐姿能促进躯体运动并有益于腰部健康。 | Henry Wang Kaitlyn J.Weiss Mason C.Haggerty Jacqueline E.Heath | 2014 | Journal of Sport and Health Science2014，3，4： | 3 |
| 2 | A comparison between chemical and gas hypoxia as models of global ischemia in zebrafish (Danio rerio)显示文摘Background:Zebrafish models for neurovascular diseases offer new methods for elucidation of molecular pathways to tissue damage.External fertilization and high fecundity provide opportunities for transgenics and other forms of genetic manipulation that are more accessible than offered by mammalian models of disease.Furthermore,behavioral analyses of zebrafish allow for connection of molecular pathways to organismal outputs such as locomotion,learning,and memory.Unfortunately,a zebrafish model of hypoxia-ischemia has been slow to catch on,possibly due to hypoxia exposure protocols that are challenging to reproduce and result in high mortality.Methods:In this study,we have introduced a predictable and simple method of hypoxia induction,the addition of sodium sulfite to aquarium water.The effects of this treatment on zebrafish locomotion were compared to those of zebrafish exposed to hypoxia induced by nitrogen gas bubbling,a method used in previous reports.Results:We found that hypoxia induced by sodium sulfite significantly impaired locomotion in the hours following treatment,and its effects did not differ from those caused by nitrogen gas hypoxia.Conclusion:These results indicate that hypoxia by sodium sulfite represents an effective and easily reproducible method for the study of hypoxia-ischemia in zebrafish. | Kaitlyn M.Marino Emani R.Silva James A.Windelborn | 2020 | Animal Models and Experimental Medicine2020，3，3： | 3 |
| 3 | Bile acids and sphingolipids in non-alcoholic fatty liver disease显示文摘Non-alcoholic fatty liver disease (NAFLD) is one of the fastest-growing diseases, and its global prevalence is estimated to increase >50% by 2030. NAFLD is comorbid with metabolic syndrome, obesity, type 2 diabetes, and insulin resistance. Despite extensive research efforts, there are no pharmacologic or biological therapeutics for the treatment of NAFLD. Bile acids and sphingolipids are well-characterized signaling molecules. Over the last few decades, researchers have uncovered potential mechanisms by which bile acids and sphingolipids regulate hepatic lipid metabolism. Dysregulation of bile acid and sphingolipid metabolism has been linked to steatosis, inflammation, and fibrosis in patients with NAFLD. This clinical observation has been recapitulated in animal models, which are well-accepted by experts in the hepatology field. Recent transcriptomic and lipidomic studies also show that sphingolipids are important players in the pathogenesis of NAFLD. Moreover, the identification of bile acids as activators of sphingolipid-mediated signaling pathways established a novel theory for bile acid and sphingolipid biology. In this review, we summarize the recent advances in the understanding of bile acid and sphingolipid-mediated signaling pathways as potential contributors to NAFLD. A better understanding of the pathologic effects mediated by bile acids and sphingolipids will facilitate the development of new diagnostic and therapeutic strategies for NAFLD. | Kaitlyn G.Jackson Grayson W.Way Huiping Zhou | 2022 | Chinese Medical Journal2022，，10： | 2 |
| 4 | Detection of micrometastases in peritoneal washings of gastric cancer patients by the reverse transcriptase polymerase chain reaction显示文摘 | Kimberly Moore Dalal Yanghee Woo Kaitlyn Kelly Charles Galanis Mithat Gonen Yuman Fong Daniel G. Coit | 2008 | Gastric Cancer2008，，4： | 2 |
| 5 | MicroRNA-Antagonism Regulates Breast Cancer Stemness and Metastasis via TET-Family-Dependent Chromatin Remodeling显示文摘 | Su Jung Song Laura Poliseno Min Sup Song Ugo Ala Kaitlyn Webster Christopher Ng Gary Beringer Nicolai J. Brikbak Xin Yuan Lewis C. Cantley Andrea L. Richardson Pier Paolo Pandolfi | 2013 | Cell2013，，： | 1 |
| 6 | Cultured endothelial cells display endogenous activation of the canonical Wnt signaling pathway and express multiple ligands, receptors, and secreted modulators of Wnt signaling 显示文摘 | Goodwin Anne Sullivan Kaitlyn D' Amore Patricia | 2006 | Dev Dyn2006，235，11： | 1 |
| 7 | Need for speed: Evaluating slopes of OCD recovery in behavior therapy enhanced with d -cycloserine显示文摘 | Gregory S. Chasson Ulrike Buhlmann David F. Tolin Sowmya R. Rao Hannah E. Reese Theresa Rowley Kaitlyn S. Welsh Sabine Wilhelm | 2010 | Behaviour Research and Therapy2010，，： | 1 |
| 8 | Peritoneal debulking/intraperitoneal chemotherapy—non‐sarcoma显示文摘 | Kaitlyn J. Kelly Garrett M. Nash | 2014 | J Surg Oncol2014，，1： | 1 |
| 9 | RT-PCR Increases Detection of Submicroscopic Peritoneal Metastases in Gastric Cancer and Has Prognostic Significance显示文摘 | Joyce Wong Kaitlyn Kelly Arjun Mittra Mithat Gonen Peter Allen Yuman Fong Daniel Coit | 2012 | Journal of Gastrointestinal Surgery2012，，5： | 1 |
| 10 | Evaluation of the treatment of pectus carinatum with compressive orthotic bracing using three dimensional body scans显示文摘 | Kaitlyn E. Wong George E. Gorton David B. Tashjian Michael V. Tirabassi Kevin P. Moriarty | 2014 | Journal of Pediatric Surgery2014，，： | 1 |
| 11 | Cohesion group appro- ach for evolutionary analysis of tyra, a protein family with wide-ranging substrate specificities显示文摘 | Carol B Terrence D Kaitlyn H | 2008 | Microbiol Mol Biol2008，72，1： | 1 |
| 12 | Vein Involvement During Pancreaticoduodenectomy: Is There a Need for Redefinition of “Borderline Resectable Disease”?显示文摘 | Kaitlyn J. Kelly Emily Winslow David Kooby Neha L. Lad Alexander A. Parikh Charles R. Scoggins Syed Ahmad Robert C. Martin Shishir K. Maithel H. J. Kim Nipun B. Merchant Clifford S. Cho Sharon M. Weber | 2013 | Journal of Gastrointestinal Surgery2013，，7： | 1 |
| 13 | RT-PCR Increases Detection of Submicroscopic Peritoneal Metastases in Gastric Cancer and Has Prognostic Significance显示文摘 | Joyce Wong Kaitlyn Jane Kelly Arjun Mittra Mithat Gonen Peter Allen Yuman Fong Daniel Coit | 2012 | Journal of Gastrointestinal Surgery2012，，5： | 1 |
| 14 | Complications in the spine associated with type 2 diabetes:The role of advanced glycation end-products显示文摘Type 2 diabetes mellitus(T2D)is an increasingly prevalent disease with numerous comorbidities including many in the spine.T2D is strongly linked with vertebral fractures,intervertebral disc(IVD)degeneration,and severe chronic spinal pain.Yet the causative mechanism for these musculoskeletal impairments remains unclear.The chronic hyperglycemic state in T2D promotes the formation of advanced glycation end-products(AGEs)in tissues,and the accumulation of AGEs may play a role in musculoskeletal complications by modifying the extracellular matrix,impairing cellular homeostasis,and perpetuating an inflammatory cascade via its receptor(RAGE).The AGE and RAGE associated alterations in extracellular matrix composition and morphological features of the vertebral bodies and IVDs are likely contributors to the incidence and severity of spinal pathologies in T2D.This review will broadly examine the effects of AGEs on tissues in the spine in the context of T2D,with an emphasis on the changes in the vertebrae and the IVD.Along with the clinical and epidemiological findings,we will provide an overview of preclinical rodent models of T2D that exhibit deficits in the IVD and vertebral bone.Elucidating the role of AGEs and RAGE will be crucial for understanding the disease mechanisms and translation therapies of musculoskeletal pathologies in T2D. | Kaitlyn Broz Remy E.Walk Simon Y.Tang | 2021 | Medicine in Novel Technology and Devices2021，，3： | 1 |
| 15 | Paracrine regulation of pa-ncreatic cancer cell invasion by peripheral nerves显示文摘 | Ziv G Oren C Kaitlyn K | 2010 | J NatlCancer Inst2010，102，2： | 1 |
| 16 | Synthesis of new two-dimensional titanium carbonitride Ti_(2)C_(0.5)N_(0.5)T_(x)MXene and its performance as an electrode material for sodium-ion battery显示文摘Two-dimensional(2D)layered transition metal carbides/nitrides,called MXenes,are attractive alternative electrode materials for electrochemical energy storage.Owing to their metallic electrical conductivity and low ion dif-fusion barrier,MXenes are promising anode materials for sodium-ion batteries(SIBs).Herein,we report on a new 2D carbonitride MXene,viz.,Ti_(2)C_(0.5)N_(0.5)T_(x)(T_(x) stands for surface terminations),and the only second carbonitride after Ti_(3) CNT_(x) so far.A new type of in situ HF(HCl/KF)etching condition was employed to synthesize multilayer Ti_(2)C_(0.5)N_(0.5)T_(x) powders from Ti_(2)AlC_(0.5)N_(0.5).Spontaneous intercalation of tetramethylammonium followed by sonication in water allowed for large-scale delamination of this new titanium carbonitride into 2D sheets.Multilayer Ti_(2)C_(0.5)N_(0.5)T_(x) powders showed higher specific capac-ities and larger electroactive surface area than those of Ti_(2)CT_(x) powders.Multi-layer Ti_(2)C_(0.5)N_(0.5)T_(x) powders show a specific capacity of 182 mAh g^(-1) at 20 mA g^(-1),the highest among all reported MXene electrodes as SIBs with excellent cycling stability. | Kun Liang Anika Tabassum Ahmad Majed Chaochao Dun Feipeng Yang Jinghua Guo Kaitlyn Prenger Jeffrey JUrban Michael Naguib | 2021 | InfoMat2021，3，12： | 1 |
| 17 | Randomized trial of surgical cutdown versus percutaneous access in transfemoral TAVR显示文摘 | Elizabeth M. Holper Rebeca J. Kim Michael Mack David Brown William Brinkman Morley Herbert Wells Stewart Kaitlyn Vance Bruce Bowers Todd Dewey | 2014 | Cathet Cardiovasc Intervent2014，，3： | 1 |
| 18 | Impact of a Pilot, Pharmacy-Led Tobacco Cessation Medication Protocol at Discharge in a Community Hospital显示文摘 | Carly M. McKenzie Rachana Patel Kaitlyn R. Eder | 2017 | Journal of Pharmacy and Pharmacology2017，5，9： | 0 |
| 19 | Ring artifacts removal in X-ray-induced acoustic computed tomography显示文摘X-ray-induced acoustic computed tomography(XACT)is a hybrid imaging modality for detecting X-ray absorption distribution via ultrasound emission.It facilitates imaging from a single projection X-ray illumination,thus reducing the radiation exposure and improving imaging speed.Nonuniform detector response caused by the interference between multichannel data acquisition for ring array transducers and amplifier systems yields ring artifacts in the reconstructed XACT images,which compromises the image quality.We propose model-based algorithms for ring artifacts corrected XACT imaging and demonstrate their effcacy on numerical and experimental measurements.The corrected reconstructions indicate significantly reduced ring artifacts as compared to their conventional counterparts. | Prabodh Kumar Pandey Hari Om Aggrawal Siqi Wang Kaitlyn Kim An Liu Liangzhong Xiang | 2022 | Journal of Innovative Optical Health Sciences2022，15，3： | 0 |
| 20 | Effects of personalized exercise prescriptions and social media delivered through mobile health on cancer survivors’physical activity and quality of life显示文摘Purpose This study aimed to examine the effects of a multi-component mobile health intervention(wearable,apps,and social media)on cancer survivors’(CS')physical activity(PA),quality of life,and PA determinants compared to exercise prescription only,social media only,and attention control conditions.Methods A total of 126 CS(age=60.37±7.41 years,mean±SD)were recruited from the United States.The study duration was 6 months and participants were randomly placed into 4 groups.All participants received a Fitbit tracker and were instructed to install its companion app to monitor their daily PA.They(1)received previously established weekly personalized exercise prescriptions via email,(2)received weekly Facebook health education and interacted with one another,(3)received both Conditions 1 and 2,or(4)were part of the control condition,meaning they adopted usual care.CS PA daily steps,quality of life(i.e.,physical health and mental health),and PA determinants(e.g.,self-efficacy,social support)were measured at baseline,3 months,and 6 months.Results The final sample size included 123 CS.The results revealed only the multi-component condition had greater improvements in PA daily steps than the control condition post-intervention(95%confidence interval(95%CI):368–2951;p<0.05).Similarly,those in the multi-component condition had significantly greater increased physical health than the control condition(95%CI:–0.41 to–0.01;p<0.05)over time.In addition,the social media condition had significantly greater increased perceived social support than the control condition(95%CI:0.01–0.93;p<0.05).No other significant differences on outcomes were identified.Conclusion The study findings suggest that the implementation of a multi-component mobile health intervention had positive effects on CS PA steps and physical health.Also,offering social media intervention has the potential to improve CS perceived social support. | Zan Gao Suryeon Ryu Wanjiang Zhou Kaitlyn Adams Mohamed Hassan Rui Zhang Anne Blaes Julian Wolfson Ju Sun | 2023 | Journal of Sport and Health Science2023，12，6： | 0 |
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