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| 1 | Identification of coastal wetlands of international importance for waterbirds:a review of China Coastal Waterbird Surveys 2005–2013显示文摘Background:China's coastal wetlands belong to some of the most threatened ecosystems worldwide.The loss and degradation of these wetlands seriously threaten waterbirds that depend on wetlands.Methods:The China Coastal Waterbird Census was organized by volunteer birdwatchers in China's coastal region.Waterbirds were surveyed synchronously once every month at 14 sites,as well as irregularly at a further 18 sites,between September 2005 and December 2013.Results:A total of 75 species of waterbirds met the 1 % population level Ramsar listing criterion at least once at one site.The number of birds of the following species accounted for over 20 % of the total flyway populations at a single site:Mute Swan(Cygnus olor),Siberia Crane(Grus leucogeranus),Far Eastern Oystercatcher(Haematopus osculans),Bar-tailed Godwit(Limosa lapponica),Spotted Greenshank(Tringa guttifer),Great Knot(Calidris tenuirostris),Spoon-billed Sandpiper(Calidris pygmeus),Saunders' s Gull(Larus saundersi),Relict Gull(Larus relictus),Great Cormorant(Phalacrocorax carbo),Eurasian Spoonbill(Platalea leucorodia),Black-faced Spoonbill(Platalea minor) and Dalmatian Pelican(Pelecanus crispus).A total of 26 sites supported at least one species of which their number met the1 % criterion.Forty-two species met the 1 % criterion in the Yellow River Delta,Shandong;29 at the Cangzhou coast,Hebei and 26 species at the Lianyungang coast,Jiangsu.Conclusions:The results highlight the international importance of China's coastal wetlands for waterbirds.This study also demonstrates that participation of local birdwatchers in waterbird surveys results in data that are invaluable not only for understanding the current status of waterbirds in China's coastal regions but also for waterbird conservation and management. | Qingquan Bai Jianzhong Chen Zhihong Chen Guotai Dong Jiangtian Dong Wenxiao Dong Vivian Wing Kan Fu Yongxiang Han Gang Lu Jing Li Yang Liu Zhi Lin Derong Meng Jonathan Martinez Guanghui Ni Kai Shan Renjie Sun Suixing Tian Fengqin Wang Zhiwei Xu Yat-tung Yu Jin Yang Zhidong Yang Lin Zhang Ming Zhang Xiangwu Zeng | 2015 | Chinese Birds2015，，3： | 20 |
| 2 | Acupuncture improves dendritic structure and spatial learning and memory ability of Alzheimer's disease mice显示文摘Acupuncture can improve the cognitive state of Alzheimer's disease, but its mechanism is not clear. Dendritic atrophy and synaptic loss in Alzheimer's disease brain are positively correlated with cognitive damage. Therefore, we speculated that the effect of acupuncture on improving cognitive function may be associated with reduced dendritic damage in the brain. Acupuncture at Qihai(CV6), Zhongwan(CV12), Danzhong(CV17), bilateral Zusanli(ST36), and bilateral Xuehai(SP10) acupoints was performed once a day(1-day rest after 6-day treatment) for 14 consecutive days. Senescence-accelerated mouse prone 8(SAMP8) mice without acupuncture and senescence-accelerated mouse resistant 1(SAMR1) mice were used as normal controls. After 14 days of treatment, spatial learning and memory ability of mice was assessed in each group using the Morris water maze. Dendritic changes of pyramidal cells in the hippocampal CA1 region were analyzed by quantitative Golgi staining. Our results showed that acupuncture shortened escape latency and lengthened retention time of the former platform quadrant in SAMP8 mice. Further, SAMP8 mice exhibited a significant increase in the number of apical and basal dendritic branches and total length of apical and basal dendrites after acupuncture. These results suggest that acupuncture improves spatial learning and memory ability of middle-aged SAMP8 mice by ameliorating dendritic structure. | Bo-Hong Kan Jian-Chun Yu Lan Zhao Jie Zhao Zhen Li Yan-Rong Suo Jing-Xian Han | 2018 | Neural Regeneration Research2018，13，8： | 18 |
| 3 | Efficacy and safety of sunitinib in the treatment of metastatic renal cell carcinoma显示文摘背景酷氨酸 kinase 禁止者(TKI ) sunitinib,为变形肾的房间癌(RCC ) 的第一线治疗的首先指向的代理人,指向脉管的 endothelial 生长因素(VEGF ) 小径。如果高血压是有效预兆的 factor.Methods,这研究的目的是在对待变形清楚房间的 RCC 调查 sunitinib 的功效和安全并且证实有变形 RCC 的 36 个病人的一个总数在 2008 年 6 月和 2010 年 12 月之间被注册。在他们之中, 29 个案例是第一线治疗, 7 个案例在首要的 cytokine 或 sorafinib 治疗上的前进。所有病人的病理被证实在清楚的房间类型占优势。Sunitinib 单音治疗在每日的口头的治疗的重复 6 星期的周期被管理 4 个星期,到 2 个星期列在后面离开在 34 个病人;并且 3 个病人连续地与 37.5 mg/d 被管理直到疾病前进或不能接受的毒性发生了。全面反应率和安全被评估。我们根据中部的后续是的血压 level.Results 把病人划分了成组 A 和组 B 15 个月(10 个周期,范围 1.5-30.0 月(1-20 周期)) 。十个病人(29.4 ) 完成了部分回答(PR ) ;23 个病人(67.6 ) 表明了持续 2 个周期的稳定的疾病(SD ) 。十七个病人(50 ) 在后续期间得了进步疾病(PD ) 。中部的没有前进的幸存(PFS ) 是 15 个月(范围 3.0-28.5 ) 月。9 个病人的一个总数死了;全面幸存没被到达;死亡病人的中部的幸存时间是 13 个月(范围 7-24 ) 月。最普通的不利事件是手脚症候群(77.8 ) , thrombocytopenia (75.0 ) ,高血压(61.1 ) 和腹泻(46.0 ) 。最不利的事件由治疗打断是可逆的。22 个病人(61.1 ) 得了高血压;并且高血压与很长时间被联系到疾病前进和长全面的幸存(P=0.004, 0.000,分别地) 这研究的结果表明的 .Conclusions 功效和可管理的不利事件与变形清楚的房间 RCC 为病人在首要或第二线的治疗作为一个单个代理人 sunitinib 介绍。进一步,联系 sunitinib 的高血压可以是为在变形 RCC 的治疗功效的一个强壮的预兆的标记。 | LI Xue-song WU Xiang ZHAO Peng-ju HUANG Li-hua SONG Yi GONG Kan SHEN Cheng YU Wei SONG Gang ZHAO Zheng ZHANG Zheng ZHANG Qian WANG Gang HE Zhi-song ZHOU Li-qun JIN Jie | 2011 | Chinese Medical Journal2011，，18： | 17 |
| 4 | Science and Prediction of Heavy Rainfall over China:Research Progress since the Reform and Opening-Up of New China显示文摘This paper reviews the major progress on development of the science and prediction of heavy rainfall over China since the beginning of the reform and opening-up of new China(roughly between 1980 and 2019).The progress of research on the physical mechanisms of heavy rainfall over China is summarized from three perspectives:1)the relevant synoptic weather systems,2)heavy rainfall in major sub-regions of China,and 3)heavy rainfall induced by typhoons.The development and application of forecasting techniques for heavy rainfall are summarized in terms of numerical weather prediction techniques and objective forecasting methods.Greatly aided by the rapid progress in meteorological observing technology and substantial improvement in electronic computing,studies of heavy rainfall in China have advanced to investigating the evolution of heavy-rain-producing storms and observational analysis of the cloud microphysical features.A deeper and more systematic understanding of the synoptic systems of importance to the production of heavy rainfall has also been developed.Operational forecast of heavy rainfall in China has changed from subjective weather event forecasts to a combination of both subjective and objective quantitative precipitation forecasts,and is now advancing toward probabilistic quantitative precipitation forecasts with the provision of forecast uncertainty information. | Yali LUO Jisong SUN Ying LI Rudi XIA Yu DU Shuai YANG Yuanchun ZHANG Jing CHEN Kan DAI Xueshun SHEN Haoming CHEN Feifan ZHOU Yimin LIU Shenming FU Mengwen WU Tiangui XIAO Yangruixue CHEN Huiqi LI Mingxin LI | 2020 | Journal of Meteorological Research2020，34，3： | 10 |
| 5 | Effects of dynamic ventilatory factors on ventilatorinduced lung injury in acute respiratory distress syndrome dogs显示文摘BACKGROUND:Mechanical ventilation is a double-edged sword to acute respiratory distress syndrome(ARDS) including lung injury,and systemic inflammatory response high tidal volumes are thought to increase mortality.The objective of this study is to evaluate the effects of dynamic ventilatory factors on ventilator induced lung injury in a dog model of ARDS induced by hydrochloric acid instillation under volume controlled ventilation and to investigate the relationship between the dynamic factors and ventilator-induced lung injuries(VILI) and to explore its potential mechanisms.METHODS:Thirty-six healthy dogs were randomly divided into a control group and an experimental group.Subjects in the experimental group were then further divided into four groups by different inspiratory stages of flow.Two mL of alveolar fluid was aspirated for detection of IL-8 and TNF-α.Lung tissue specimens were also extracted for total RNA,IL-8 by western blot and observed under an electronic microscope.RESULTS:IL-8 protein expression was significantly higher in group B than in groups A and D.Although the IL-8 protein expression was decreased in group C compared with group B,the difference was not statistically significant.The TNF-α ray degree of group B was significantly higher than that in the other groups(P<0.01),especially in group C(P>0.05).The alveolar volume of subjects in group B was significantly smaller,and cavity infiltration and cell autolysis were marked with a significant thicker alveolar septa,disorder of interval structures,and blurring of collagenous and elastic fiber structures.A large number of necrotic debris tissue was observed in group B.CONCLUSION:Mechanical ventilation with a large tidal volume,a high inspiratory flow and a high ventilation frequency can cause significant damage to lung tissue structure.It can significantly increase the expression of TNF-α and IL-8 as well as their mRNA expression.Furthermore,the results of our study showed that small tidal ventilation significantly reduces the release of proinflammatory media.This finding suggests that greater deterioration in lung injury during ARDS is associated with high inspiratory flow and high ventilation rate. | Rui-lan Wang Kan Xu Kang-long Yu Xue Tang Hui Xie | 2012 | World Journal of Emergency Medicine2012，3，4： | 8 |
| 6 | Effects of cefodizime on chemokines of liver tissues in mice with immunological hepatic injury显示文摘背景长期的肝的发炎被淋巴细胞的累积在感染的地点在织物以内从血和保留作为增加的招募的后果描绘。CXC chemokine ligand 16 (CXCL16 ) mRNA 被检测了在发炎并且正常的肝纸巾并且强烈在在一个鼠科的模型的受伤的肝纸巾的 upregulated。这研究的目的是与免疫学的在老鼠在肝纸巾的 CXCL16 mRNA 上调查 cefodizime 的效果肝的 injury.Methods 免疫学的鼠科的模型肝的损害被杆菌 Calmette Guerin 和 Lipoposaccharide 导致。有肝的损害随机被分到模型组, cefodizime 组和 ceftriaxone 组的免疫学的老鼠。三个组连续地被给代理人七天,肝织物的 CXCL16 mRNA 与正常对待的控制组一起坚定、对比盐。反向的抄写聚合酶链反应在 CXCL16 mRNA 的表达式是的肝 tissues.Results 习惯于试金 CXCL16 mRNA 层次显著地,更高,在模型,组和 ceftriaxone 比在控制组和 cefodizime 组( P 0.05 )组织,显示在模型组和 ceftriaxone 组的鼠标是 immunodeficient 。在在控制组和 cefodizime 组之间的 CXCL16 mRNA 的表情没有统计差别。同样,在在模型组和 ceftriaxone 组之间的 CXCL16 mRNA 的表达式的统计差别都没被检测(P 0.05 ).Conclusion Cefodizime 有效地把淋巴细胞的渗入简化为肝纸巾并且与免疫学的在鼠标在肝纸巾由减少的 CXCL16 mRNA 减轻肝损坏肝的损害。 | WANG Peng KAN Quan-cheng YU Zu-jiang LI Ling PAN Xue | 2011 | Chinese Medical Journal2011，，5： | 8 |
| 7 | Evaluation of efficacy and safety of sunitinib regimen in 22 patients with metastatic renal cell carcinoma: at least 12-month follow-up显示文摘 | ZHANG Cui-jian ZHAO Peng-ju LI Xue-song ZHAO Jing HUANG Li-hua SONG Yi GONG Kan SHEN Cheng YU Wei SONG Gang ZHAO Zheng ZHANG Zheng ZHANG Qian HE Zhi-song JIN Jie ZHOU Li-qun | 2013 | Chinese Medical Journal2013，，15： | 7 |
| 8 | Adjuvant chemotherapy with S-1 plus oxaliplatin improves survival of patients with gastric cancer after D2 gastrectomy: A multicenter propensity score-matched study显示文摘AIM To investigate the safety and efficacy of S-1 plus oxaliplatin(SOX) as an adjuvant chemotherapy regimen in gastric cancer(GC) after D2 dissection.METHODS GC Patients who underwent D2 gastrectomy from September 2009 to December 2011 in four Chinese institutions were enrolled. Patients with stage ⅠB-ⅢC GC, who received adjuvant SOX treatment were matched by propensity scores with those who underwent surgery alone and those who conducted capecitabine plus oxaliplatin(XELOX) regimen. Disease-free survival(DFS) and overall survival(OS) were compared among the groups. In addition, adverse events in SOX patients were analyzed.Of 1944 GC patients who underwent D2 dissection, 867 were included for analysis. One hundred and seventeen patients treated with SOX were matched to 234 patients who conducted surgery alone. Fifty-seven patients treated with SOX were matched to 57 patients who received XELOX. The estimated five-year DFS was 57.5% in the adjuvant SOX group which was higher than that(44.6%) in the surgery alone group(P = 0.001); and the estimated five-year OS was 68.3% which was higher than that(45.8%) of surgery alone group(P < 0.001). Survival benefit was also revealed in stage III and > 60 years old subgroups(P < 0.001 and P = 0.015, respectively). Compared with XELOX regimen, SOX showed no significant difference in DFS(P = 0.340) and OS(P = 0.361). The most common ≥ 3 grade adverse events of SOX regimen were neutropenia(22.6%), leukopenia(8.9%) and thrombocytopenia(5.6%).CONCLUSION Compared with surgery alone, SOX regimen significantly improves the long-term survival and has acceptable toxicity in patients with stage ⅠB-ⅢC GC after D2 dissection. It may be a novel adjuvant chemotherapy regimen in GC patients. | Deng-Feng Ren Fang-Chao Zheng Jun-Hui Zhao Guo-Shuang Shen Raees Ahmad Shui-Sheng Zhang Yu Zhang Jie Kan Li Dong Zi-Yi Wang Fu-Xing Zhao Jiu-Da Zhao | 2018 | World Journal of Clinical Cases2018，6，10： | 7 |
| 9 | Functional Metabolomics Reveals that Astragalus Polysaccharides Improve Lipids Metabolism through Microbial Metabolite 2-Hydroxybutyric Acid in Obese Mice显示文摘Polysaccharides are widely present in herbs with multiple activities,especially immunity regulation and metabolic benefits for metabolic disorders.However,the underlying mechanisms are not well under-stood.Functional metabolomics is increasingly used to investigate systemic effects on the host by iden-tifying metabolites with particular functions.This study explores the mechanisms underlying the metabolic benefits of Astragalus polysaccharides(APS)by adopting a functional metabolomics strategy.The effects of APS were determined in eight-week high-fat diet(HFD)-fed obese mice.Then,gas chromatography–time-of-flight mass spectrometry(GC–TOFMS)-based untargeted metabolomics was performed for an analysis of serum and liver tissues,and liquid chromatography–tandem mass spectrom-etry(LC–MS/MS)-based targeted metabolomics was performed.The potential functions of the metabo-lites were tested with in vitro and in vivo models of metabolic disorders.Our results first confirmed the metabolic benefits of APS in obese mice.Then,metabolomics analysis revealed that APS supplemen-tation reversed the HFD-induced metabolic changes,and identified 2-hydroxybutyric acid(2-HB)as a potential functional metabolite for APS activity that was significantly decreased by a HFD and reversed by APS.Further study indicated that 2-HB inhibited oleic acid(OA)-induced triglyceride(TG)accumula-tion.It was also found to stimulate the expression of proteins in lipid degradation in hepatocytes and TG lipolysis in 3T3-L1 cells.Moreover,it was found to reduce serum TG and regulate the proteins involved in lipid degradation in high-fat and high-sucrose(HFHS)-fed mice.In conclusion,our study demonstrates that the metabolic benefits of APS are at least partially due to 2-HB generation,which modulated lipid metabolism both in vitro and in vivo.Our results also highlight that functional metabolomics is practical for investigating the mechanism underlying the systemic benefits of plant polysaccharides. | Bingbing Li Ying Hong Yu Gu Shengjie Ye Kaili Hu Jian Yao Kan Ding Aihua Zhao Wei Jia Houkai Li | 2022 | Engineering2022，8，2： | 6 |
| 10 | A macroscopic multi-mechanism based constitutive model for the thermo-mechanical cyclic degeneration of shape memory effect of NiTi shape memory alloy显示文摘A macroscopic based multi-mechanism constitutive model is constructed in the framework of irreversible thermodynamics to describe the degeneration of shape memory effect occurring in the thermo-mechanical cyclic deformation of NiTi shape memory alloys(SMAs). Three phases,austenite A, twinned martensite Mtand detwinned martensite M^d, as well as the phase transitions occurring between each pair of phases( A → M^t, M^t→ A, A → M^d,M^d→ A, and M^t→ M^d) are considered in the proposed model. Meanwhile, two kinds of inelastic deformation mechanisms, martensite transformation-induced plasticity and reorientation-induced plasticity, are used to explain the degeneration of shape memory effects of NiTi SMAs. The evolution equations of internal variables are proposed by attributing the degeneration of shape memory effect to the interaction between the three phases(A, M^t, and M^d) and plastic deformation. Finally, the capability of the proposed model is verified by comparing the predictions with the experimental results of NiTi SMAs. It is shown that the degeneration of shape memory effect and its dependence on the loading level can be reasonably described by the proposed model. | Chao Yu Guozheng Kang Qianhua Kan | 2017 | Acta Mechanica Sinica2017，33，3： | 6 |
| 11 | Combined acupuncture and HuangDiSan treatment affects behavior and synaptophysin levels in the hippocampus of senescence-accelerated mouse prone 8 after neural stem cell transplantation显示文摘Sanjiao acupuncture and Huang Di San can promote the proliferation, migration and differentiation of exogenous neural stem cells in senescence-accelerated mouse prone 8(SAMP8) mice and can improve learning and memory impairment and behavioral function in dementia-model mice. Thus, we sought to determine whether Sanjiao acupuncture and Huang Di San can elevate the effect of neural stem cell transplantation in Alzheimer's disease model mice. Sanjiao acupuncture was used to stimulate Danzhong(CV17), Zhongwan(CV12), Qihai(CV6), bilateral Xuehai(SP10) and bilateral Zusanli(ST36) 15 days before and after implantation of neural stem cells(5 × 105) into the hippocampal dentate gyrus of SAMP8 mice. Simultaneously, 0.2 m L Huang Di San, containing Rehmannia Root and Chinese Angelica, was intragastrically administered. Our results demonstrated that compared with mice undergoing neural stem cell transplantation alone, learning ability was significantly improved and synaptophysin m RNA and protein levels were greatly increased in the hippocampus of mice undergoing both Sanjiao acupuncture and intragastric administration of Huang Di San. We conclude that the combination of Sanjiao acupuncture and Huang Di San can effectively improve dementia symptoms in mice, and the mechanism of this action might be related to the regulation of synaptophysin expression. | Chun-lei Zhou Lan Zhao Hui-yan Shi Jian-wei Liu liang-wei Shi Bo-hong Kan Zhen Li lian-chun Yu Jing-xian Han | 2018 | Neural Regeneration Research2018，13，3： | 6 |
| 12 | Enteroaggregative Escherichia aoliisolated from Chinese diarrhea patients with high-pathogenicity island of Yersinia'xs involved in synthesis of siderophore yersiniabactin显示文摘AIM: To investigate the distribution of 12 high-pathogenicity island (HPI) genes and the relation between HPI genes and expression of yersiniabactin (Ybt) in enteroaggregative E.coli(EAggEC) isolated from Chinese diarrhea patients.METHODS: The distribution of 12 HPI genes was investigated by PCR and DNA hybridization in two prototype strains of EAggEC, EAggEC 17-2, EAggEC O42, and 6 clinical EAggEC isolates from China. The production of siderophore Ybt in HPI-positive strains was detected by reporter gene bioassay to determine the relation between HPI genes and expression of Ybt. Flow cytometry was used to detect fluorescent signal of the reporter strain that could designate production of Ybt.RESULTS: Seven strains were HPI-positive and one strain was HPI-negative. Six of the seven HPI-positive strains were inserted into asnT-tRNA site. Moreover, seven EAggEC HPI-positive strains revealed enhanced fluorescence signal but the EAggEC HPI-negative strain did not. However, there was a difference in Ybt expression condition and level among these seven EAggEC HPI-positive strains. Although UFT073 strain, the prototype strain of uropathogenic E.coli(UPEC), carried the complete HPI core part, we did not detect the expression of Ybt in it.CONCLUSION: EAggEC HPI-positive strains can express the Ybt system, but the presence of HPI core part does not mean the functional expression of Ybt. | Jing Hu Biao Kan Zhi-Hua Liu Shou-Yi Yu | 2005 | World Journal of Gastroenterology2005，11，37： | 5 |
| 13 | Acute gastrointestinal injury in critically ill patients with COVID-19 in Wuhan,China显示文摘BACKGROUND The coronavirus disease 2019(COVID-19)is spreading rapidly around the world.Most critically ill patients have organ injury,including acute respiratory distress syndrome,acute kidney injury,cardiac injury,or liver dysfunction.However,few studies on acute gastrointestinal injury(AGI)have been reported in critically ill patients with COVID-19.AIM To investigate the prevalence and outcomes of AGI in critically ill patients with COVID-19.METHODS In this retrospective study,demographic data,laboratory parameters,AGI grades,clinical severity and outcomes were collected.The primary endpoints were AGI incidence and 28-d mortality.RESULTS From February 10 to March 102020,83 critically ill patients out of 1314 patients with COVID-19 were enrolled.Seventy-two(86.7%)patients had AGI during hospital stay,of these patients,30 had AGI gradeⅠ,35 had AGI gradeⅡ,5 had AGI gradeⅢ,and 2 had AGI gradeⅣ.The incidence of AGI gradeⅡand above was 50.6%.Forty(48.2%)patients died within 28 days of admission.Multiple organ dysfunction syndrome developed in 58(69.9%)patients,and septic shock in 16(19.3%)patients.Patients with worse AGI grades had worse clinical variables,a higher incidence of septic shock and 28-d mortality.Sequential organ failure assessment(SOFA)scores(95%CI:1.374-2.860;P<0.001),white blood cell(WBC)counts(95%CI:1.037-1.379;P=0.014),and duration of mechanical ventilation(MV)(95%CI:1.020-1.340;P=0.025)were risk factors for the development of AGI gradeⅡand above.CONCLUSION The incidence of AGI was 86.7%,and hospital mortality was 48.2%in critically ill patients with COVID-19.SOFA scores,WBC counts,and duration of MV were risk factors for the development of AGI gradeⅡand above.Patients with worse AGI grades had a higher incidence of septic shock and 28-d mortality. | Jia-Kui Sun Ying Liu Lei Zou Wen-Hao Zhang Jing-Jing Li Yu Wang Xiao-Hua Kan Jiu-Dong Chen Qian-Kun Shi Shou-Tao Yuan | 2020 | World Journal of Gastroenterology2020，26，39： | 5 |
| 14 | The Deep Geophysical Structure of the Middle Section of the Longmen Mountains Tectonic Belt and its Relation to the Wenchuan Earthquake显示文摘Investigation of the deep geophysical structure of the Longmen Mountains tectonic belt and its relation to the Wenchuan Earthquake is important for the study of earthquakes. By using magnetotelluric sounding profiles of the Luqu–Zhongjiang and Anxian–Suining; seismic sounding profiles of the Sichuan Maowen–Chongqing Gongtan, the Qinghai Huashi Gorge–Sichuan Jianyang, and the Batang–Zizhong; and magnetogravimetric data of the Longmen Mountains region, the deep geophysical structure of the Songpan–Ganzi block, the western Sichuan foreland basin, and the Longmen Mountains tectonic belt and their relation was discussed. The eastward extrusion of the Qinghai–Tibet Plateau thrusts the Songpan–Ganzi block upon the Yangtze block, which obstructs the eastward movement of the Qinghai–Tibet Plateau. The Maoxian–Wenchuan, Beichuan–Yingxiu, and Anxian–Guanxian faults of the Longmen Mountains fault belt dip to northwest with different dip angles and gradually converge in the deeper parts. Geophysical structure suggests that an intracrustal low-velocity, low-resistivity, and high-conductivity layer is common between the middle and upper crust west of the Longmen Mountains tectonic belt but not in the upper Yangtze block. The Sichuan Basin has a thick low-resistance sedimentary layer on a stable high-resistance basement; moreover, there are secondary paleohighs and depression structures at the lower part of the western Sichuan foreland basin with characteristic of high magnetic anomalies, whereas the Songpan–Ganzi block has a high resisitivity cover of upper crust and continues to a low-resistance layer. Considering the Longmen Mountains tectonic belt as the boundary, there are Bouguer gravity anomalies of 'one belt between two zones.' Thus, we infer that there is a corresponding relation between the inferred crystalline basement of the Songpan block and the underlying basin basement of the Longmen Mountains fault belt. Furthermore, there may be an extensive ancient Yangtze block, which is west of the Ruoergai block. In addition, the crust–mantle ductile shear zone under the Longmen Mountains tectonic belt is the main fault, whereas the Beichuan–Yingxiu and Anxian–Guanxian faults at the surface are earthquake faults. The Wenchuan Ms 8.0 earthquake might be attributed to the collision of the Yangtze block and the Qinghai–Tibet Plateau. The eastward obduction of the eastern edge of the Qinghai–Tibet Plateau and eastward subduction of its deeper part under the influence of the collision of the Indian, Pacific, and Philippine Plates with the Eurasia Plate might have caused the Longmen Mountains tectonic belt to cut the Moho and extend to the middle and upper crust; thus, creating high stress concentration and rapid energy release zone. | YU Nian WANG Xuben HU Xiangyun CAI Xuelin KAN Aike ZHAO Ning | 2014 | Acta Geologica Sinica(English Edition)2014，88，2： | 4 |
| 15 | Two-qubit entangled state teleportation via optimal POVM and partially entangled GHZ state显示文摘 | Kan Wang Xu-Tao Yu Zai-Chen Zhang | 2018 | Frontiers of physics2018，13，5： | 4 |
| 16 | Discovery,Identification and Comparative Analysis of Non-Specific Lipid Transfer Protein (nsLtp) Family in Solanaceae显示文摘Plant non-specific lipid transfer proteins (nsLtps) have been reported to be involved in plant defense activity against bacterial and fungal pathogens. In this study, we identified 135 (122 putative and 13 previously identified) Solanaceae nsLtps, which are clustered into 8 different groups. By comparing with Boutrot's nsLtp classification, we classified these eight groups into five types (I, II, IV, IX and X). We compared Solanaceae nsLtps with Arabidopsis and Gramineae nsLtps and found that (1) Types I, II and IV are shared by Solanaceae, Gramineae and Arabidopsis; (2) Types III, V, VI and VIII are shared by Gramineae and Arabidopsis but not detected in Solanaceae so far; (3) Type VII is only found in Gramineae whereas type IX is present only in Arabidopsis and Solanaceae; (4) Type X is a new type that accounts for 52.59% Solanaceae nsLtps in our data, and has not been reported in any other plant so far. We further built and compared the three-dimensional structures of the eight groups, and found that the major functional diversification within the nsLtp family could be predated to the monocot/dicot divergence, and many gene duplications and sequence variations had happened in the nsLtp family after the monocot/dicot divergence, especially in Solanaceae. | Wanfei Liu Dawei Huang Kan Liu Songnian Hu Jun Yu Gang Gao Shuhui Song | 2010 | Genomics, Proteomics & Bioinformatics2010，8，4： | 4 |
| 17 | Radioactivity monitoring in environmental water and air around QNPP显示文摘Results of environmental radioactivity monitoring around Qinshan Nuclear Power Plant (QNPP) are reported in this paper. From 1992 to 2005, concentrations of 90Sr, 137Cs and 3H in terrestrial freshwater are (4.4±1.7) mBq·L-1, (0.3±0.1) mBq·L-1 and (1.6±0.5) Bq·L-1, respectively, and (2.8±2.4) Bq·L-1 of 3H in rainwater. Concentrations of 90Sr, 137Cs and 3H in the seawater samples collected from sea area nearby QNPP are (5.4±4.1) mBq·L-1, (0.7±0.2) mBq·L-1 and (1.0±0.5) Bq·L-1, respectively. Concentrations of 90Sr, 137Cs and 3H in the total waste water discharged from NPP-I are (4.0±1.8) m Bq·L-1, (1.0±0.5) mBq·L-1 and (2.8±2.2) Bq·L-1, respectively, and (1.4±0.4) Bq·L-1 of 3H in seawater sampled from No.1 outlet. Atomspheric 3H concentration in 1993~2005 at two monitoring sites is (78.9±96.3) and (64.2±40.2) mBq·m-3, respectively, with an increasing trend after 2003. Atmospheric 14C concentrations at the two sites are in the same levels as the background and data of the reference site. | XIANG Yuanyi WANG Kan ZHANG Yu CAO Zhonggang YE Jida WANG Hongfeng | 2007 | Nuclear Science and Techniques2007，18，5： | 4 |
| 18 | A NOVEL STEROID FROM EICHHORNIA CRASSIPES显示文摘6(?)-Hydroxy-stigmasta-4,22-diene-3-one 1,a novel steroid,was isolated from the Eichhornia Crassipes.Its structure was deter-mined by 1H and 13C NMR spectroscopy and further confirmed by authen-tic sample,which was synthesized from stigmasterol 2. | Hou Ming WU Hui Qiang ZHOU Sheng yu HUANG Kan MA Xia Fei LAO State Key Laboratory of Bio-organic and Natural Products Chemistry Shanghai Institute of Organic Chemistry,Academia Sinica 345 LingLing Lu,Shanghai 200032Shu Wen YU Wen Hao SUN Zi Wen YU Shanghai Institute of Plant Physiology Academia Sinica,Shanghai 200032 | 1991 | Chinese Chemical Letters1991，2，7： | 3 |
| 19 | Locally repairable codes with strict availability from linear functions显示文摘Dear editor,In distributed storage systems, data is divided into small pieces and stored across a number of nodes. Since node failures are inevitable, redundancy is necessary. During the long run, the redundancy needs to be replenished. Regenerating codes were proposed to decrease repair bandwidth of distributed storage systems by accessing more nodes and downloading less data from each node [1, 2]. Locally repairable codes [3] improve the repairability of distributed storage system | Yu ZHANG Haibin KAN | 2018 | Science China(Information Sciences)2018，61，10： | 3 |
| 20 | Identifi cation of egg protein-derived peptides as xanthine oxidase inhibitors:virtual hydrolysis,molecular docking,and in vitro activity evaluation显示文摘The purpose of this study was to screen the xanthine oxidase(XO)inhibitory peptides from egg white proteins through virtual hydrolysis,in vitro activity validation,and molecular docking.The results demonstrated that tripeptide EEK from ovalbumin exhibited potent XO inhibitory activity with an IC50 value of 141μmol/L.The molecular docking results showed that tripeptide EEK bound with the active center of XO via 3 carbon hydrogen bond interactions,2 salt bridges,5 conventional hydrogen bond interactions,and 4 attractive charge interactions.The residues Glu802,Phe1009,and Arg880 may play key roles in the XO catalytic reaction.Especially,the key intermolecular forces of inhibiting XO activity may be special type of hydrogen bonds including carbon hydrogen bond interactions and attraction charge interactions.The novel tripeptide EEK is potential candidates for controlling hyperuricemia. | Zhipeng Yu Yaxin Cao Ruotong Kan Huizhuo Ji Wenzhu Zhao Sijia Wu Jingbo Liu David Shiuan | 2022 | Food Science and Human Wellness2022，11，6： | 3 |
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