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| 1 | Destabilization of strigolactone receptor DWARF14 by binding of ligand and E3-1igase signaling effector DWARF3显示文摘 | Li-Hua Zhao X Edward Zhou Wei Yi Zhongshan Wu Yue Liu Yanyong Kang Li Hou Parker W de Waal Suling Li Yi Jiang Adrian Scaffidi Gavin R Flematti Steven M Smith Vinh Q Lam Patrick R Griffin YonghongWang Jiayang Li Karsten Melcher H Eric Xu | 2015 | Cell Research2015，25，11： | 7 |
| 2 | More synergetic cooperation of Yamanaka factors in induced pluripotent stem cells than in embryonic stem cells显示文摘在 pluripotency 的正式就职的核心管理者最近在体的房间 reprogramming 期间被发现了的 Yamanaka 因素的角色。我们的以前的学习发现 Yamanaka 因素在维持胚胎的茎(ES ) 房间 pluripotency 调整一个发展发信号网络。这里,我们完全证实 reprogrammed 导致了 pluripotent 茎(iPS ) 细胞并且由薄片薄片试金在这些细胞分析了 Yamanaka 因素的全球倡导者占有。我们发现 565 基因的倡导者是由在 iPS 房间的四个 Yamanaka 因素的合作界限, 10 褶层增加什么时候与他们在 ES 房间的绑定相比。,在 ES 房间 Oct4, Sox2,或 Klf4 在 iPS 房间在激活并且镇压的基因同等地散布的一个单个 Yamanaka 因素占据的倡导者在激活的主要在镇压基因和 c-Myc 散布了。薄片薄片数据的小径分析表明 Yamanaka 因素在 iPS 房间, 12 在之中是普通的调整了 16 条发展发信号小径, 4 与在 ES 房间调整的小径相比是唯一的。我们进一步在 iPS 房间分析了另一最近出版的薄片薄片数据集并且观察了类似的结果,显示出为揭示 pluripotency 维护和新生的性质的薄片薄片正小径分析的力量。下次,我们试验性地测试了压抑的发信号小径之一并且发现它的抑制确实改进了房间 reprogramming 的效率。一起拿,我们建议有一个核心为 pluripotency 必要的发展发信号网络与 TGF- ,刺猬, Wnt,是的 p53 压抑(殷) 管理者和 Jak-STAT,房间周期,焦点的粘附, adherens 连接作为活跃(杨) ;并且 Yamanaka 因素 synergistically 在 Yin-Yang 调整他们导致 pluripotency 的平衡方法。 | Jinyan Huang Taotao Chen Xiaosong Liu Jing Jian Jinsong Li Dangsheng Li X Shirley Liu Wei Li Jiuhong Kang Gang Pei | 2009 | Cell Research2009，19，10： | 4 |
| 3 | Role and pitfalls of hepatic helical multi-phase CT scanning in differential diagnosis of small hemangioma and small hepatocellular carcinoma显示文摘RoleandpitfalsofhepatichelicalmultiphaseCTscanningindiferentialdiagnosisofsmalhemangiomaandsmalhepatocelularcarcinomaYANFuH... | YAN FuHua1, ZENG MengSu1 and ZHOU KangRong1Keywords liver neoplasms/radiography carcinoma, hepatocellular/radiography hemangioma/radiography diagnosis, differential tomography, Xray computed | 1998 | World Journal of Gastroenterology1998，4，4： | 4 |
| 4 | The structural basis of the dominant negative phenotype of the Gαi1β1Y2 G203A/A326S heterotrimer显示文摘 | Ping LIU Ming-zhu JIA X Edward ZHOU Parker W DE WAAL Bradley M DICKSON Bo LlU Li HOU Yan-ting YIN Ya n-yong KANG Yi SHI Karsten MELCHER H Eric XU Yi JIANG | 2016 | Acta Pharmacologica Sinica2016，37，9： | 3 |
| 5 | 基于工作地点的分组干预对高血压控制的影响:一项随机临床研究显示文摘基于工作地点的干预可能为一种管理高血压的有效方法。但是目前缺少针对中国工作人群高血压控制情况的研究。本研究旨在评估基于工作地点的多组分别干预策略对改善血压控制的影响。研究设计及受试者:研究者在2013年1月至2014年12月于中国20个城区的60个工作地点进行了一系列高血压管理的随机临床试验。工作地点随机分为干预组(n=40)和对照组(n=20)。每个工作地点的受试者都需要完成一项横断面调查。 | 袁源(摘译) 叶鹏(审校) Wang Z Wang X Shen Y Li S Chen Z Zheng C Kang Y Jiang L Hao G Chang C Gao R | 2020 | 中华高血压杂志2020，28，6： | 3 |
| 6 | 中国成年女性初潮年龄与高血压风险的关系:大型国家代表性群体研究结果显示文摘本研究纳入中国高血压调查中年龄≥18岁的女性234867例,旨在探索中国成年女性初潮年龄与高血压风险的相关性。参与者被要求完成标准问卷,血压测量和体格检查由经过培训的医务人员完成。采用Spearman相关性分析探索初潮年龄和其他个体特征的相关性。采用logistic回归根据初潮年龄计算高血压发生的OR。结果显示,中国女性平均初潮年龄为14.8岁。 | 袁源(摘译) 郑武洪(审校) Chen L Zhang L Chen Z Wang X Zheng C Kang Y Zhou H Wang Z Gao R | 2021 | 中华高血压杂志2021，29，10： | 3 |
| 7 | Docosahexaenoic acid suppresses arachidonic acid-induced proliferation of LS-174T human colon carcinoma cells显示文摘AIM:To investigate the impact of arachidonic acid (AA) and docosahexaenoic acid (DHA) and their combination on colon cancer cell growth.METHODS:The LS-174T colon cancer cell line was used to study the role of the prostaglandin precursor AA and the omega-3 polyunsaturated fatty acid DHA on cell growth. Cell viability was assessed in XTT assays. For analysis of cell cycle and cell death,flow cytometry and DAPI staining were applied. Expression of cyclooxygenase-2 (COX-2),p21 and bcl-2 in cells incubated with AA or DHA was examined by real-time RT-PCR. Prostaglandin E2 (PGE2) generation in the presence of AA and DHA was measured using a PGE2-ELISA.RESULTS:AA increased cell growth,whereas DHAreduced viability of LS 174T cells in a time-and dose-dependent manner. Furthermore,DHA down-regulated mRNA of bcl-2 and up-regulated p21. Interestingly,DHA was able to suppress AA-induced cell proliferation and significantly lowered AA-derived PGE2 formation. DHA also down-regulated COX-2 expression. In addition to the effect on PGE2 formation,DHA directly reduced PGE2-induced cell proliferation in a dose-dependent manner. CONCLUSION:These results suggest that DHA can inhibit the pro-proliferative effect of abundant AA or PGE2. | Piet Habbel Karsten H Weylandt Katja Lichopoj Johannes Nowak Martin Purschke Jing-Dong Wang Cheng-Wei He Daniel C Baumgart Jing X Kang | 2009 | World Journal of Gastroenterology2009，15，9： | 2 |
| 8 | Proteomic fingerprints for potential application to early diagnosis of severe acute respiratory syndrome 显示文摘 | Kang X Xu Y Wu X | 2005 | Clin Chem2005，51，1： | 1 |
| 9 | Selection and validation of optimal siRNA target sites for RNAi-mediated gene silencing显示文摘 | LUO Q KANG Q SONG W X | 2007 | Gene2007，395，12： | 1 |
| 10 | 2D structure with rectangular grids woven by coordination chains and pseudo-metal wires 显示文摘 | ZHANG H X KANG B S DENG L R | 2001 | Inorg Chem Commun2001，4，： | 1 |
| 11 | Effect of 6-Dioetylamino-1,3,5- triazine-2,4-dithiol Concentration on the Polymer Plating on Iron Plates显示文摘 | Mori K Kang Z X Oishi Y | 2005 | PolymJ2005，37，11： | 1 |
| 12 | Low-temperature catalytic combustion of chlorobenzene over MnOx-CeO2 mixed oxide catalysts显示文摘 | Wang X Y Kang Q Li D | 2008 | Catalysis Communications2008，9，： | 1 |
| 13 | In-situ stress measurement and stress distribution characteristics in underground coal mines in China显示文摘 | Kang H P Zhang X Si L P | 2010 | Engineering Geology2010，，116： | 1 |
| 14 | Detection of pandemic influenza A/ H1N1/2009 virus by real-time reverse transcription polymerase chain reaction显示文摘 | Wu W Kang X Bai Z | 2010 | J Virol Methods2010，165，2： | 1 |
| 15 | Surface studies of pristine and surface modified polypyrrole films显示文摘 | ZHANG X KANG E T NEOH K G | 1996 | Journal of Applied Polymer Science1996，60，： | 1 |
| 16 | Transgenic mice: fat-1 mice convert n45 to n- 3 fatty acids显示文摘 | KANG J X WU L | 2004 | Nature2004，427，： | 1 |
| 17 | SUMO-Specific Protease 1 Is Essential for Stabilization of HIFla during Hypoxia 显示文摘 | Cheng J Kang X Zhang S | 2007 | Cell2007，131，3： | 1 |
| 18 | Human neutralizing SARS-CoV specific Fab molecules generated by phage display显示文摘 | Kang X Yang BA Hu Y | 2006 | Clin Vaccine Immunol2006，13，8： | 1 |
| 19 | Sol - gel process doped ZnO nanopowders and their grown growth显示文摘 | KANG X Y WANG T D HAN Y | 1997 | Mater Res Bull1997，32，9： | 1 |
| 20 | Effect of CuO or/and V2O5 oxide additives on Bi2O3-ZnO-Ta2O5 based ceramics显示文摘 | Shen B Yao X Kang L P | 2004 | Ceram Int2004，30，： | 1 |
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