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43篇 您的检索式：作者名="Kelly Young"

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	题名	作者	年代	出处	被引量
1	Differentiation of human embryonic stem cells derived mesenchymal stem cells into corneal epithelial cells after being seeded on decellularized SMILE-derived lenticules显示文摘AIM: To evaluate the feasibility of mesenchymal stem cells(MSCs) to differentiate into corneal epithelial cells after being seeded on the decellularized small incision lenticule extraction(SMILE)-derived lenticules. METHODS: The fresh lenticules procured from patients undergoing SMILE for the correction of myopia were decellularized. The MSCs were subsequently cultivated on those denuded lenticules. The MSCs without lenticules were used as a control. The proliferation activity of the MSCs after seeding 24 h was quantitatively determined with the Cell Counting Kit-8(CCK-8) assay. Immunofluorescence staining and quantitative reverse transcription polymerase chain reaction(qRT-PCR) were used to assess the marker expression in differentiated MSCs. RESULTS: The data showed that both fresh and decellularized lenticules could significantly promote the proliferation of MSCs, compared to that in control(P=0.02 for fresh lenticules, P=0.001 for decellularize ones, respectively). The MSCs seeded on both lenticules were positive for cytokeratin 3(CK3) staining. The expression of CK3 increased 5-fold in MSCs seeded on fresh lenticules and 18-fold on decellularized ones, compared to that in control. There was a significant difference in the expression of CK3 in MSCs seeded on fresh and decellularized lenticules(P<0.001). The expression of CK8 and CK18 was similar in pure MSCs and MSCs seeded on fresh lenticules(P>0.05), while the expression of these markers was decreased in MSCs seeded on decellularized ones. CONCLUSION: These results suggest that the decellularized lenticules might be more suitable for MSCs to differentiate into corneal epithelial cells, which offersthe prospect of a novel therapeutic modality of SMILEderived lenticules in regenerative corneal engineering.	Yao Chen Ye-Wei Yin Yang Zhao Xiao-Ying Wu Kelly Young Wei-Tao Song Xiao-Bo Xia Dan Wen	2019	International Journal of Ophthalmology(English edition)2019，12，5：	2
2	Pharmacist and physician views on col- laborative practice: Findings from the community pharmaceutical care pro- ject显示文摘	Kelly DV Bishop L Young S	2013	CPJ/RPC2013，146，4：	1
3	Microwave activation of enzymatic catalysis 显示文摘	Young D D Nichols J Kelly R M	2008	Journal of the American ChemicalSociety2008，130，10：	1
4	Pharmacist and physician views on collaborative practice:findings from the community pharmaceutical care project显示文摘	KELLY D V BISHOP L YOUNG S	2013	Can Pharm J2013，146，4：	1
5	Dimensions of adolescent subjective social status within the school community: Description and correlates显示文摘	Helen Sweeting Patrick West Robert Young Shona Kelly	2010	Journal of Adolescence2010，，3：	1
6	RAPD markers flanking the Are gene for anthracnose resistance in common bean 显示文摘	Young R A Kelly J D	1996	J Amer Soc Hort Sci1996，121，：	1
7	Impaired attention is central to the cognitive deficits observed in alpha 7 deficient mice显示文摘	Young JW Crawford N Kelly JS		0，，：	1
8	Enzymatic modification of polyester 显示文摘	YOON Mee Young JIM Kellis POULOSE A J	2002	AATCC Review2002，6，2：	1
9	Pharmacist and physi- cian views on collaborative practice:Findings from the com- munity pharmaceutical care project 显示文摘	Kelly DV Bishop L Young S	2013	Can Pharm J (Ott)2013，146，4：	1
10	Definition of the bacterial N-glycosylation site consensus sequence显示文摘	Kowarik M Young NM Numao S Schulz BL Hug I Callewaert N Mills DC Watson DC Hernandez M Kelly JF Wacker M Aebi M		0，，09：	1
11	Changes in sources and perceived quality of social supports among formerly homeless persons receiving assertive community treatment services显示文摘	Carton AD Young MS Kelly KM	2010	Community Ment Health J2010，46，2：	1
12	Microwave aetiva tion of enzymatic catalysis显示文摘	YOUNG D D NICHOLS J KELLY R M	2008	Journal of the American Chemical Society2008，130，10：	1
13	Levels and confounders of morning cortisol collected from adolescents in a naturalistic (school) setting 显示文摘	KELLY S J YOUNG R SWEETING H	2008	Psychoneuroendocrinology2008，33，9：	1
14	Changes in sources and perceivedquality of social supports among formerly homeless persons receivingassertive community treatment services 显示文摘	Carton AD Young MS Kelly KM	2010	Community Ment HealthJ2010，46，2：	1
15	Clinical response to an oral prostaglandin analogue in patients with interstitial cystitis显示文摘	Kelly JD Young MR Johnston SR	1998	Eur Urol1998，34，：	1
16	Quantifying relationships between land‐use gradients and structural and functional indicators of stream ecological integrity 显示文摘	Clapcott JE Collier KJ Death RG Goodwin EO Harding JS Kelly D Leathwick JR Young RG	2012	Freshwater Biol2012，57，1：	1
17	Pharmacistand physician views on collaborativepractice: Findings from the community pharmaceutical care project显示文摘	Kelly DV Bishop L Young S	2013	CPJ / RPC2013，146，4：	1
18	Pathogenesis of Ebola Hemorrhagic Fever in Primate Models显示文摘	Thomas W. Geisbert Howard A. Young Peter B. Jahrling Kelly J. Davis Tom Larsen Elliott Kagan Lisa E. Hensley	2003	The American Journal of Pathology2003，，6：	1
19	查看详情显示文摘	Soo E C Aubry A J Logan S M Guerry P Kelly J F Young N M Thibault P		0，，03：	1
20	Serotonin transporter polymorphisms, microstructural white matter abnormalities and remission of geriatric depression显示文摘	George S. Alexopoulos Christopher F. Murphy Faith M. Gunning-Dixon Charles E. Glatt Vassilios Latoussakis Robert E. Kelly Dora Kanellopoulos Sibel Klimstra Kelvin O. Lim Robert C. Young Matthew J. Hoptman	2009	Journal of Affective Disorders2009，，1：	1

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