2篇
您的检索式：作者名="Kemei Jiang"
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| 1 | Simultaneous enhancement in strength and ductility of Fe_(50)Mn_(30)Co_(10)Cr_(10)high-entropy alloy via nitrogen alloying显示文摘The effect of nitrogen on microstructural evolution and tensile properties of transformation-induced plasticity(TRIP)Fe_(50)Mn_(30)Co_(10)Cr_(10)HEAs was investigated.Nitrogen was fully introduced in solid solution by pressure-induced melting technique.Nitrogen addition turned the TRIP alloy to a twinning-induced plasticity(TWIP)alloy,and simultaneously improved the strength and elongation.For the nitrogen-doped HEA,the high yield strength is mainly resulted from the friction stress via interstitial strengthening effect,and the high ductility is originated from retained high strain-hardening capability via the successive onset of dislocation accumulation and deformation twinning.The strain-hardening behavior and microstructural evolution at specified strains were revealed. | Yu Han Huabing Li Hao Feng Kemei Li Yanzhong Tian Zhouhua Jiang | 2021 | Journal of Materials Science & Technology2021，，6： | 0 |
| 2 | Molecular recognition triggered aptazyme cascade for ultrasensitive detection of exosomes in clinical serum samples显示文摘Exosomes have attracted widespread interest due to their inherent advantages in tumor diagnosis and treatment monitoring.However,it is still a big challenge for highly sensitive and specific detection of exosome in real complexed samples.Herein,a molecular recognition triggered aptazyme cascade strategy was developed for ultrasensitive detection of cancer exosomes in clinical serum samples.In this design,one target exosome could capture a large quantity of aptazymes for the first-step signal amplification.And then the captured aptazyme was activated and recycled to release the fluorophore-labelled substrate strand for a cascaded signal amplification.Notably,the activation of aptazyme only occurs whenithas bound with target exosome,ensuring a low background.The experimental results show that the limit of detection(LOD)and the limit of quantification(LOQ)are 3.5×10^(3) particles/μL and 1.7×10^(4) particles/μL,respectively,which is comparable to the results of most existed fluorescence-based exosome probes.Moreover,this assay possesses high specificity to distinguish exosomes derived from other cell lines.Furthermore,this fluorescence probe was utilized in cancer patient and healthy serum samples successfully,suggesting its great potential for clinical diagnosis and biological studies. | Kemei Jiang Yanan Wu Juan Chen Mingqing Shi Hong-Min Meng Zhaohui Li | 2021 | Chinese Chemical Letters2021，32，5： | 0 |
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