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| 1 | α2,6-唾液酸转移酶(ST6GalI)的表达对结肠癌细胞唾液酸化的影响显示文摘目的 研究结肠癌细胞LS174T转染正义和反义的α2 ,6唾液酸转移酶 (ST6GalI)cDNA对结肠癌细胞表面唾液酸化及肿瘤细胞粘附功能的影响 .方法 结肠癌细胞株LS174T转染正义ST6GalIcDNA或反义ST6GalIcDNA的部分序列的表达载体pcDNA3 .1,以RT -PCR检测转染子ST6GalImRNA的表达 ,流式细胞仪检测细胞表面α2 ,6唾液酸含量 .结果 转染正义ST6GalIcDNA的克隆显示ST6GalImRNA的表达增强以及接骨木凝集素 (SNA)与细胞表面成分的结合增加 ;而转染反义ST6GalIcDNA的部分序列的细胞克隆的ST6GalImRNA的表达减少 ,SNA与细胞表面成分的结合力降低 .结论 ST6GalI的表达直接影响细胞表面α2 ,6-连接的唾液酸水平并调节肿瘤细胞的粘附功能 .利用反义核酸技术抑制ST6GalI的表达并降低肿瘤细胞表面α2 。 | 林绍强 李君武 王晓玉 Wolfgang Kemmner Perter M.Schlag | 2004 | 现代临床医学生物工程学杂志2004，10，1： | 4 |
| 2 | Efficiency of adjuvant active specific immunization with Newcastle disease virus modified tumor cells in colorectal cancer patients following resection of liver metastases: results of a prospective randomized trial显示文摘 | T. Schulze W. Kemmner J. Weitz K.-D. Wernecke V. Schirrmacher P. M. Schlag | 2009 | Cancer Immunology Immunotherapy2009，，1： | 1 |
| 3 | ARFI-based tissue elasticity quantification and kidney graft dysfunction: First clinical experiences显示文摘 | K.F. Stock B.S. Klein M.T. Vo Cong C. Regenbogen S. Kemmner M. Büttner S. Wagenpfeil E. Matevossian L. Renders U. Heemann C. Küchle | 2011 | 2011 (1-4)2011，，1： | 1 |
| 4 | Separation of tumor cells from a suspersion of dissociated numan colorectal carcinoma tissue by means of monoclonal antibody-coated magnetic beads显示文摘 | Kemmner W | 1992 | J Immunol Methods1992，147，2： | 1 |
| 5 | Efficiency of adjuvant active specific immunization with Newcastle disease virus modified tumor cells in colorectal cancer patients following resection of liver metastases:results of a prospective randomized trial显示文摘 | SCHULZE T KEMMNER W WEITZ J | | 0，，01： | 1 |
| 6 | Efficiency of adjuvant active specific immunization with Newcastle disease virus modified tu- mor cells in colorectal cancer patients following resection of liver metastases: results of a prospective randomized trial显示文摘 | Schulze T Kemmner W Weitz J | 2009 | Cancer Im- munol Immunother2009，58，1： | 1 |
| 7 | Glycosyltransferase expression in human colonic tissue examined by oligonucleotide arrays 显示文摘 | Kemmner W Roefzaad C Haensch W | 2003 | Biochim Biophys Acta2003，1621，3： | 1 |
| 8 | Efficiency of adjuvant active specific immunization with Newcastle disease virus modified tumor ceils in colorectal cancer patients following resection of liver metastases : results of a prospective randomized trial 显示文摘 | Schulze T Kemmner W Weitz J | 2009 | Cancer Immunol Immunother2009，58，1： | 1 |
| 9 | Efficiency of adjuvant active specific immunization with Newcastle disease virus modified tumor cells in colorectal cancer patients following resection of liver metastases: results of a prospective randomized trial显示文摘 | Schulze T Kemmner W Weitz J | 2009 | Cancer Immunol Immunother2009，58，1： | 1 |
| 10 | Cell surface alpha 2,6-sialylation affects adhesion of breast carcinoma cells显示文摘 | Lin SQ Kemmner W Grigull S | 2002 | Exp Cell Res2002，276，1： | 1 |
| 11 | Altered mRNA expression of glycosyltransferases in human colorectal carcinomas and liver metastases显示文摘 | Petretti T Kemmner W Schulze B | 2000 | Gut2000，46，3： | 1 |
| 12 | Silencing of human ferrochelatase causes abundant protoporphyrin-IX accumulation in colon cancer显示文摘 | WOLFGANG KEMMNER KAYIU WAN STEFFEN RUTTINGER | 2008 | The Faseb Journal2008，22，08： | 1 |
| 13 | Preparation and characterization of differently aggregated colorectal carcinoma cell subpopulations from surgical specimens 显示文摘 | Bosch J Brossmer R Kemmner W | 1998 | Cancer Detect Prev1998，22，4： | 1 |
| 14 | Cell surface alpha 2,6-sialylation affects adhesion of breast carcinoma cells显示文摘 | Lin SQ Kemmner W Grigull S | 2002 | Exp Cell Res2002，276，1： | 1 |
| 15 | Altered mRNA expression of glycosyltransferases in human colorectal carcinomas and liver metastases显示文摘 | Petretti T Kemmner W Schulze B | 2000 | Gut2000，46，3： | 1 |
| 16 | Altered mRNA expression of glycosyltransferases in human colorectal carcinomas and liver metastases显示文摘 | Petretti T Kemmner W Sehulze B | 2000 | Gut2000，46，3： | 1 |
| 17 | Cell surface alpha 2,6 sialylation affects adhesion of breast carcinoma cells显示文摘 | Lin S Kemmner W Grigull S | 2002 | Exp Cell Res2002，276，1： | 1 |
| 18 | Cell surface α 2,6-sialylation affects adhesion of breast carcinoma cells 显示文摘 | Lin S Kemmner W Grigull S | 2002 | Exp Cell Res2002，276，1： | 1 |
| 19 | Sialic acid dependent cell adhesion to collagen IV correlates with in vivo tumorigenicity of the human colon carcinoma sublines HCT 116, HCT 116a and HCT116b 显示文摘 | Morgenthaler J Kemmner W Brossmer R | 1990 | Biochem Biophys Res Commun1990，171，2： | 1 |
| 20 | Cell surface alpha 2,6 sialylation effets adhesion of breast carcinoma cells显示文摘 | Lin S Kemmner W Grigulle S | 2007 | Exp Cell Res2007，276，1： | 1 |
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