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| 1 | Transient receptor potential channel A1 involved in calcitonin gene-related peptide release in neurons显示文摘Transient receptor potential channel A1 is one of the important transducers of noxious stimuli in the primary afferents,which may contribute to generation of neurogenic inflammation and hyperalgesia.The present study was designed to investigate if activation of transient receptor potential channel A1 may induce calcitonin gene-related peptide release from the primary afferent neurons.We found that application of allyl isothiocyanate,a transient receptor potential channel A1 activator,caused calcitonin gene-related peptide release from the cultured rat dorsal root ganglion neurons.Knockdown of transient receptor potential channel A1 with an antisense oligodeoxynucleotide prevented calcitonin gene-related peptide release by allyl isothiocyanate application in cultured dorsal root ganglion neurons.Thus,we concluded that transient receptor potential channel A1 activation caused calcitonin gene-related peptide release in sensory neurons. | Nobumasa Ushio Yi Dai Shenglan Wang Tetsuo Fukuoka Koichi Noguchi | 2013 | Neural Regeneration Research2013，8，32： | 2 |
| 2 | Sentinel lymphadenectomy in breast cancer: identification of sentinel lymph node and detection of metastases显示文摘 | Masakuni Noguchi Koichiro Tsugawa Etsuro Bando Futoshi Kawahara Koichi Miwa Kunihiko Yokoyama Ken-ichi Nakajima Norihisa Tonami | 1999 | Breast Cancer Research and Treatment1999，，2： | 1 |
| 3 | Usefulness of magnetic resonance imaging for diagnosing deep anorectal abscesses显示文摘 | Ryo Maruyama Tsuyoshi Noguchi Masahiro Takano Koichi Takagi Norikazu Morita Ryuichi Kikuchi Yuzo Uchida | 2000 | Diseases of the Colon & Rectum2000，，： | 1 |
| 4 | Suppression of neuropeptides’ mRNA expression by herbal medicines in a rat model of peripheral inflammation显示文摘 | Yi Dai Kenji Miki Tetsuo Fukuoka Atsushi Tokunaga Toshiya Tachibana Eiji Kondo Koichi Noguchi | 1999 | Life Sciences1999，，1： | 1 |
| 5 | MAPK activation in nociceptive neurons and pain hypersensitivity显示文摘 | Koichi Obata Koichi Noguchi | 2004 | Life Sciences2004，，： | 1 |
| 6 | Preparation and electrochemical characteris tics of LiNi1/3Co1/3Mn1/3O2 coated with metal oxides coating显示文摘 | DECHENG L YASUHIRO K KOICHI K NOGUCHI H SATO Y | 2006 | Journal of Power Sources2006，160，： | 1 |
| 7 | Conversion hepatectomy for hepatocellular carcinoma with main portal vein tumour thrombus after lenvatinib treatment: A case report显示文摘BACKGROUND Hepatocellular carcinoma(HCC)accompanied by portal vein tumour thrombus(PVTT)presents an aggressive disease course,worsening liver function reserve,and a high recurrence rate.Clinical practice guidelines recommend systemic therapy as the first-line option for HCC with portal invasion.However,to achieve longer survival in these patients,the treatment strategy should be concluded with removal of the tumour by locoregional therapy.We experienced a case of initially unresectable HCC with main PVTT converted to radical hepatectomy after lenvatinib treatment.CASE SUMMARY A 59-year-old male with chronic hepatitis C infection visited our clinic as a regular post-surgery follow-up.Contrast-enhanced abdominal computed tomography revealed a liver mass diffusely located at the lateral segment with a massive PVTT extending from the umbilical portion to the main and contralateral third-order portal branches.With the diagnosis of unresectable HCC with Vp4(main trunk/contralateral branch)PVTT,lenvatinib was started at 12 mg/d.The computed tomography taken 3 mo after starting lenvatinib showed regression of the PVTT,which had retreated to the contralateral first-order portal branch.He tolerated the full dose without major adverse effects.With cessation of lenvatinib for 7 d,radical left lobectomy and PVTT thrombectomy were conducted.The patient’s postoperative course was uneventful.Microscopically,the primary lesion showed fibrotic changes,with moderately to poorly differentiated tumour cells surrounded by granulation tissues in some areas.The majority of the PVTT showed necrosis.He was alive without recurrence for 8 mo.CONCLUSION This is the first case of HCC with Vp4 PVTT in which radical conversion hepatectomy was succeeded after lenvatinib treatment. | Kazuhiro Takahashi Jaejeong Kim Amane Takahashi Shinji Hashimoto Manami Doi Kinji Furuya Ryosuke Hashimoto Yohei Owada Koichi Ogawa Yusuke Ohara Yoshimasa Akashi Katsuji Hisakura Tsuyoshi Enomoto Osamu Shimomura Masayuki Noguchi Tatsuya Oda | 2021 | World Journal of Hepatology2021，13，3： | 1 |
| 8 | Adipose‐derived mesenchymal stem cells and regenerative medicine显示文摘 | Masamitsu Konno Atsushi Hamabe Shinichiro Hasegawa Hisataka Ogawa Takahito Fukusumi Shimpei Nishikawa Katsuya Ohta Yoshihiro Kano Miyuki Ozaki Yuko Noguchi Daisuke Sakai Toshihiro Kudoh Koichi Kawamoto Hidetoshi Eguchi Taroh Satoh Masahiro Tanemura Hiroak | 2013 | Develop Growth Differ2013，，3： | 1 |
| 9 | GENE EXPRESSION IN NEUROPATHIC PAIN MODELS显示文摘Fluctuations in gene expression that reflect changes in the functional demands on individual neurons are an everyday occurrence. With sustained peripheral inflammation, however, prolonged C-fiber activation alters the pattern of gene transcription in dorsal root ganglion (DRG) cells and dorsal horn neurons. Following peripheral nerve injury changes in neuronal excitability and mRNA levels in sensory neurons offer s substrate for chronic pain. Several mechanisms that contribute to increased excitability in DRG have recently been discovered. | Koichi NOGUCHI | 2001 | 神经解剖学杂志2001，17，B07： | 0 |
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