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| 1 | The role of antioxidants and pro-oxidants in colon cancer显示文摘This review focuses on the roles antioxidants and prooxidants in colorectal cancer(CRC).Considerable evidence suggests that environmental factors play key roles in the incidence of sporadic CRC.If pro-oxidant factors play an etiological role in CRC it is reasonable to expect causal interconnections between the wellcharacterized risk factors for CRC,oxidative stress and genotoxicity.Cigarette smoking,a high dietary consumption of n-6 polyunsaturated fatty acids and alcohol intake are all associated with increased CRC risk.These risk factors are all pro-oxidant stressors and their connections to oxidative stress,the intestinal microbiome,intestinal microfold cells,cyclooxygenase-2 and CRCare detailed in this review.While a strong case can be made for pro-oxidant stressors in causing CRC,the role of food antioxidants in preventing CRC is less certain.It is clear that not every micronutrient with antioxidant activity can prevent CRC.It is plausible,however,that the optimal food antioxidants for preventing CRC have not yet been critically evaluated.Increasing evidence suggests that RRR-gamma-tocopherol(the primary dietary form of vitamin E)or other'non-alpha-tocopherol'forms of vitamin E(e.g.,tocotrienols)might be effective.Aspirin is an antioxidant and its consumption is linked to a decreased risk of CRC. | William L Stone Koyamangalath Krishnan Sharon E Campbell Victoria E Palau | 2014 | World Journal of Gastrointestinal Oncology2014，6，3： | 4 |
| 2 | Tuberosity malposition and migration: Reasons for poor outcomes after hemiarthroplasty for displaced fractures of the proximal humerus显示文摘 | P Boileau S.G Krishnan L Tinsi G Walch J.S Coste D Molé | 2002 | Journal of Shoulder and Elbow Surgery2002，，5： | 2 |
| 3 | Tuberosity malposition and migration:reasons for poor outcomes after hemiarthroplasty for displaced fractures of the proximal humerus显示文摘 | Boileau P Krishnan S G Tinsi L | | 0，，05： | 2 |
| 4 | Fracture toughness of a soft sandstone 显示文摘 | Krishnan G R Zhao X L Zaman M | 1998 | Int J Rock Mech1998，35，6： | 1 |
| 5 | Tuberosity malposi-tion and migration:reasons for poor outcomes after hemi-arthroplasty for displaced fractures of the proximalhumerus显示文摘 | Boileau P Krishnan S G Tinsi L et ai | 2002 | J Shoulder Elbow Surg2002，11，5： | 1 |
| 6 | Hyperuricemiaand the risk for subclinical coronary atherosclerosis -data from a prospective observational cohort study 显示文摘 | Krishnan E Pandya BJ Chung L | 2011 | Arthritis Res Ther2011，13，2： | 1 |
| 7 | Hyperuricemia and the risk for subclinical coronary atherosclerosis - data from a prospective observational cohort study显示文摘 | Krishnan E Pandya BJ Chung L | 2011 | Arthritis Res Ther2011，13，2： | 1 |
| 8 | Cytotoxicity and weak CD40 ligand expression of CD8^+ type 2 cytotoxie T cells restricts their potential B cell helper activity显示文摘 | Sad S Krishnan L Bleackley RC | 1997 | Eur J Immunol1997，27，： | 1 |
| 9 | ECG Signal conditioning by morphological filtering 显示文摘 | Sun Y Chan K L Krishnan S M | 2002 | Computers in Biology and Medicine2002，32，6： | 1 |
| 10 | ECG signal conditioning by morphological filtering显示文摘 | SUN Y CHAN K L KRISHNAN S M | 2002 | Computers in Biology and Medicine2002，32，6： | 1 |
| 11 | Envelope Glycoprotein gB of Kaposi's sarcoma-associated herpesvirus is essential for egress from infected cells显示文摘 | Krishnan HH Sharma-Walia N Zeng L | 2005 | J Virol2005，79，10： | 1 |
| 12 | Obstetric hospitalizations in the United States for women with systemic lupus erythematosus and rheumatoid arthritis显示文摘 | Chakravarty EF Nelson L Krishnan E | 2006 | Arthritis-Rheum2006，54，3： | 1 |
| 13 | Hyperuricemia andthe risk for subclinical coronary atherosclerosis-data froma prospective observational cohort study显示文摘 | Krishnan E Pandya BJ Chung L | 2011 | Arthritis ResTher2011，13，2： | 1 |
| 14 | Tuberosity malposi- tion ang migration: Reasons for poor outcomes after hemi arthroplasty for displaced fractures of the proximal humerus显示文摘 | Boileau P Krishnan SO Tinsi L | 2002 | Shoulder Elbow Surg2002，11，3： | 1 |
| 15 | Hyperuricemia and the risk for subclinical coronary atheroselerosis-darn from a prospective observational cohort study显示文摘 | Krishnan E Pandya EJ Chung L | | 0，，02： | 1 |
| 16 | Fracture toughness of a soft sandstone 显示文摘 | Krishnan G R Zhao X L Zaman M | 1998 | International Journal of Rock Mechanics and Mining Sciences and Geomechanics Abstracts1998，35，6： | 1 |
| 17 | Predictors of therapy-related leukemia and myelodysplasia following autologous transplantation for lymphoma:an assessment of risk factors显示文摘 | Krishnan A Bhatia S Slovak M L | 2000 | Blood2000，95，5： | 1 |
| 18 | ANTIMIC: a database of antimicrobial sequences显示文摘 | Brahmachary M Krishnan S P Koh J L | 2004 | Nucleic Acids Res2004，32，： | 1 |
| 19 | Long-term cardiovascular mortality among middle-aged men with gout显示文摘 | Krishnan E Svendsen K Neaton J D Grandits G Kuller L H MRFIT Research Group | 2008 | Arch Intern Med2008，168，： | 1 |
| 20 | Serum uric acid and cardiovascu- lax disease;recent developments, and where do they leave us显示文摘 | Baker JF Krishnan E Chen L | 2005 | Am J Med2005，118，： | 1 |
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