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| 1 | Methylation-dependent loss of RIP3 expression in cancer represses programmed necrosis in response to chemotherapeutics显示文摘交往受体的蛋白质 kinase-3 (RIP3 或 RIPK3 ) 是执行 “ 的细胞的机械的必要部分; programmed”或 “ regulated”坏死。这里,我们证明那规划坏死响应许多化学疗法的代理人被激活并且贡献导致化疗的房间死亡。然而,我们证明那 RIP3 表情经常在化学疗法的死亡期间由于它的 transcriptional 开始地点, MLKL 的这样 RIP3 依赖的激活和下游地规划的坏死附近的 genomic methylation 是在癌症房间的 silenced 大部分被镇压。不过,有 hypomethylating 代理人的治疗恢复 RIP3 表示,并且从而以一种 RIP3 依赖的方式把敏感提升到 chemotherapeutics。RIP3 表示在 85% 乳癌病人与正常织物相比在肿瘤被减少,建议那 RIP3 缺乏断然在肿瘤生长 / 发展期间被选择。因为 hypomethylating 代理人在病人是相当容忍得好的,我们建议病人们可以从收到 hypomethylating 代理人与常规 chemotherapeutics 在治疗以前导致 RIP3 表示有益于的那 RIP3 缺乏的癌症。 | Gi-Bang Koo Michael J Morgan Da-Gyum Lee Woo-Jung Kim Jung-Ho Yoon Ja Seung Koo Seung I1 Kim Soo Jung Kim Mi Kwon Son Soon Still Hong Jean M Mulcahy Levy Daniel A Pollyea Craig T Jordan Pearlly Yan David Frankhouser Deedra Nicolet Kati Maharry Guido Marcucci Kyeong Sook Choi Hyeseong Cho ndrew Thorbum You-Sun Kim | 2015 | Cell Research2015，25，6： | 20 |
| 2 | Thermal and design sensitivity analyses for cooling system of injection mold, part 2: design sensitivity analysis显示文摘 | Park S J Kwon T H | 1998 | Journal of Manufacturing Science and Engineering1998，120，2： | 2 |
| 3 | Detection of single nucleonucleotide insertion of BCL/ABL region in imatinib-resistance human myelogenous leukemia SR-1 Cells显示文摘 | Park T H Kwon K E Kim H J | 2005 | Exp Mol Med2005，37，5： | 1 |
| 4 | Long-termBehaviour of Square Concrete-Filled Steel Tubular Columnsunder Axial Service Loads 显示文摘 | KWON S H KIM T H KIM J K | 2007 | Magazine of ConcreteResearch2007，59，1： | 1 |
| 5 | Thinning-based topological exploration using position possibility o显示文摘 | Kwon T Song J | 2008 | Advanced Robotics2008，22，23： | 1 |
| 6 | Comparative ge- nomic analysis of mitogen activated protein kinase gene family in grapevine显示文摘 | Hyun T K Kim J S Kwon S Y | 2010 | Genes & Oenomics2010，32，： | 1 |
| 7 | Chronic gastrointestinal problems and boweldysfunction in patients with spinal cord iniury 显示文摘 | HAN T R KIM J H KWON B S | 1998 | Spinal Cord1998，36，7： | 1 |
| 8 | Effect of group IV elements on the cutting characteristics of Ti(C, N) cermet tools and reliability analysis显示文摘 | KWON W T PARK J S KANG S | 2005 | Journal of Materials Processing Technology2005，144，： | 1 |
| 9 | A polydimethylsiloxane (PDMS) sponge for the selective absorption of oil from water显示文摘 | CHOI S J KWON T H IM H | 2011 | Acs Applied Materials & Interfaces2011，3，12： | 1 |
| 10 | Futures trading, spot market volatility, and market efficieney: The case of the Korean index futures markets 显示文摘 | Bae S C Kwon T H Park J W | 2004 | Journal of Futures Markets2004，24，12： | 1 |
| 11 | Vasomotor symptoms andmetabolic syndrome in Korean postmenopausal women 显示文摘 | Ryu K J Park H T Kwon D H | 2015 | Menopause2015，2201，： | 1 |
| 12 | Synthesis and electrochemical properties of olivine LiFePO4 as a cathode material prepared by mechanical alloying显示文摘 | Kwon S J Kim C W Jeong W T | 2004 | J Power Sources2004，137，1： | 1 |
| 13 | A full 3D finite element analysis of powder injection molding filling process including slip phenomena显示文摘 | HWANG C J KWON T H | 2002 | Ploymer Engineering and Science2002，42，1： | 1 |
| 14 | The major genetic determinants of HIV-1control affect HLA class I peptide presentation显示文摘 | International HIV Controllers Study Pereyra F Jia X McLaren P J Telenti A de Bakker P I Walker B D Ripke S Brumme C J Pulit S L Carrington M Kadie C M Carlson J M Heckerman D Graham R R Plenge R M Deeks S G Gianniny L Crawford G Sullivan J Gonzalez E Davies L Camargo A Moore JM Beattie N Gupta S Crenshaw A Burtt N P Guiducci C Gupta N Gao X Qi Y Yuki Y Piechocka-Trocha A Cutrell E Rosenberg R Moss K L Lemay P O'Leary J Schaefer T Verma P Toth I Block B Baker B Rothchild A Lian J Proudfoot J Alvino D M Vine S Addo M M Allen T M Altfeld M Henn M R Le Gall S Streeck H Haas D W Kuritzkes D R Robbins G K Shafer R W Gulick R M Shikuma C M Haubrich R Riddler S Sax P E Daar E S Ribaudo H J Agan B Agarwal S Ahern R L Allen B L Altidor S Altschuler E L Ambardar S Anastos K Anderson B Anderson V Andrady U Antoniskis D Bangsberg D Barbaro D Barrie W Bartczak J Barton S Basden P Basgoz N Bazner S Bellos N C Benson A M Berger J Bernard N F Bernard A M Birch C Bodner S J Bolan R K Boudreaux E T Bradley M Braun J F Brndjar J E Brown S J Brown K Brown S T Burack J Bush LM Cafaro V Campbell O Campbell J Carlson R H Carmichael J K Casey K K Cavacuiti C Celestin G Chambers S T Chez N Chirch L M Cimoch P J Cohen D Cohn LE Conway B Cooper D A Cornelson B Cox D T Cristofano M V Cuchural G Jr Czartoski J L Dahman J M Daly J S Davis B T Davis K Davod S M DeJesus E Dietz C A Dunham E Dunn M E Ellerin T B Eron J J Fangman J J Farel C E Ferlazzo H Fidler S Fleenor-Ford A Frankel R Freedberg K A French N K Fuchs JD Fuller J D Gaberman J Gallant J E Gandhi R T Garcia E Garmon D Gathe J C Jr Gaultier C R Gebre W Gilman F D Gilson I Goepfert P A Gottlieb M S Goulston C Groger R K Gurley T D Haber S Hardwicke R Hardy W D Harrigan P R Hawkins T N Heath S Hecht F M Henry W K Hladek M Hoffman R P Horton J M Hsu R K Huhn G D Hunt P Hupert M J Illeman M L Jaeger H Jellinger R M John M Johnson J A Johnson K L Johnson H Johnson K Joly J Jordan W C Kauffman C A Khanlou H Killian R K Kim A Y Kim D D Kinder C A Kirchner J T Kogelman L Kojic E M Korthuis P T Kurisu W Kwon D S LaMar M Lampiris H Lanzafame M Lederman M M Lee D M Lee J M Lee M J Lee E T Lemoine J Levy J A Llibre J M Liguori M A Little S J Liu A Y Lopez A J Loutfy M R Loy D Mohammed D Y Man A Mansour M K Marconi V C Markowitz M Marques R Martin J N Martin H L Jr Mayer K H McElrath M J McGhee T A McGovern B H McGowan K McIntyre D Mcleod GX Menezes P Mesa G Metroka CE Meyer-Olson D Miller A O Montgomery K Mounzer K C Nagami E H Nagin I Nahass R G Nelson M O Nielsen C Norene D L O'Connor D H Ojikutu B O Okulicz J Oladehin O O Oldfield E C Olender S A Ostrowski M Owen WF Jr Pae E Parsonnet J Pavlatos A M Perlmutter A M Pierce M N Pincus J M Pisani L Price L J Proia L Prokesch R C Pujet H C Ramgopal M Rathod A Rausch M Ravishankar J Rhame F S Richards C S Richman D D Rodes B Rodriguez M Rose R C 3rd Rosenberg E S Rosenthal D Ross P E Rubin D S Rumbaugh E Saenz L Salvaggio M R Sanchez WC Sanjana V M Santiago S Schmidt W Schuitemaker H Sestak P M Shalit P Shay W Shirvani V N Silebi V I Sizemore J M Jr Skolnik P R Sokol-Anderson M Sosman J M Stabile P Stapleton J T Starrett S Stein F Stellbrink H J Sterman FL Stone V E Stone D R Tambussi G Taplitz R A Tedaldi E M Telenti A Theisen W Torres R Tosiello L Tremblay C Tribble M A Trinh P D Tsao A Ueda P Vaccaro A Valadas E Vanig T J Vecino I Vega V M Veikley W Wade B H Walworth C Wanidworanun C Ward D J Warner D A Weber R D Webster D Weis S Wheeler D A White D J Wilkins E Winston A Wlodaver C G van't Wout A Wright D P Yang O O Yurdin D L Zabukovic B W Zachary K C Zeeman B Zhao M | 2010 | Science2010，330，6010： | 1 |
| 15 | Concomitant lower serum albumin and vitamin D levels are associated with decreased objective physical performance among Japanese community-dwelling elderly显示文摘 | Kwon J Suzuki T Yoshida H | 2007 | Gerontology2007，53，： | 1 |
| 16 | Fabrication of TiB2/Al composites by combustion synthesis of Al-Ti-B system 显示文摘 | KWON Y J KOBASHI M CHOH T | 2002 | Materials Transaction2002，43，11： | 1 |
| 17 | Analysis of Residence Time Distribu tion in the Extrusion Process Including the Effect of 3-D Cir culatory Flow 显示文摘 | J W Joo T H Kwon | 1993 | Polymer Engineering and Science1993，33，15： | 1 |
| 18 | Variation of a newcastle disease virus hemagglutinin-neuraminidase linear epitope显示文摘 | Cho S H Kwon H J Kim T E | | 0，，4： | 1 |
| 19 | Sulforaphane suppresses lipopolysaccharide-induced cyclooxygenase-2(COX-2) expression through the modulation of multiple targets in COX-2 gene promoter 显示文摘 | WOO K J KWON T K | 2012 | Int Inamunopharmacol2012，7，13： | 1 |
| 20 | Variation of a Newcastle disease virus hemagglutinin-neuramini- dase linear epitope 显示文摘 | CHO S H KWON H J KIM T E | 2008 | J Clin Microbiol2008，46，4： | 1 |
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