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| 1 | Evolution of transanal total mesorectal excision for rectal cancer:From top to bottom显示文摘The gold standard for curative treatment of locally advanced rectal cancer involves radical resection with a total mesorectal excision(TME). TME is the most effective treatment strategy to reduce local recurrence and improve survival outcomes regardless of the surgical platform used. However, there are associated morbidities, functional consequences, and quality of life(QoL) issues associated with TME; these risks must be considered during the modern-day multidisciplinary treatment for rectal cancer. This has led to the development of new surgical techniques to improve patient, oncologic, and QoL outcomes. In this work, we review the evolution of TME to the transanal total mesorectal excision(TaTME) through more traditional minimally invasive platforms. The review the development, safety and feasibility, proposed benefits and risks of the procedure, implementation and education models, and future direction for research and implementation of the TaTME in colorectal surgery. While satisfactory short-term results have been reported, the procedure is in its infancy, and long term outcomes and definitive results from controlled trials are pending.As evidence for safety and feasibility accumulates,structured training programs to standardize teaching,training, and safe expansion will aid the safe spread of the TaTME. | Sameh Hany Emile F Borja de Lacy Deborah Susan Keller Beatriz Martin-Perez Sadir Alrawi Antonio M Lacy Manish Chand | 2018 | World Journal of Gastrointestinal Surgery2018，10，3： | 18 |
| 2 | Laparoscopic versus open surgery for rectal cancer (COLOR II): short-term outcomes of a randomised, phase 3 trial显示文摘 | Martijn HGM van der Pas Eva Haglind Miguel A Cuesta Alois Fürst Antonio M Lacy Wim CJ Hop Hendrik Jaap Bonjer | 2013 | Lancet Oncology2013，，： | 17 |
| 3 | Utilization of sugar cane bagasse hemicellulosic hydrolyzate by Pichia stipitis for the production of ethanol显示文摘 | Roberto I C Lacis L S Barbosa M F S | 1991 | Proc Biochem1991，26，1： | 1 |
| 4 | Laparoscopic versus open surgery for rectal cancer (COLOR II): short-term outcomes of a randomised, phase 3 trial显示文摘 | Martijn HGM van der Pas Eva Haglind Miguel A Cuesta Alois Fürst Antonio M Lacy Wim CJ Hop Hendrik Jaap Bonjer | 2013 | Lancet Oncology2013，，： | 1 |
| 5 | Enhanced free cholesterol, SREBP 2 and StAR expression in human NASH 显示文摘 | Caballero F Ferndndez A De Lacy AM | 2009 | J Hepatol2009，50，4： | 1 |
| 6 | Plasma hydrogen peroxide production in hypertensives and normotensive subjects at genetic risk of hypertension 显示文摘 | Lacy F O Connor DT Schmid-Schonbein GW | 1998 | J Hypertens1998，16，3： | 1 |
| 7 | Enhanced free cholesterol,SREBP-2 and StAR expression in human NASH显示文摘 | Caballero F Fernández A De Lacy AM | | 0，，： | 1 |
| 8 | Lenalidomide plus dexamethasone ver- sus thalidomide plus dexamethasone in newly diagnosed multiple myeloma: a comparative analysis of 411 patients显示文摘 | Gay F Hayman SR Lacy MQ | 2010 | Blood2010，115，7： | 1 |
| 9 | Transplantation of intact pancreatic islets in rats显示文摘 | BALLINGER W F LACY P E | 1972 | Surgery1972，72，： | 1 |
| 10 | Laparoscopy-assisted colectomy versus open colectomy for treatment of non- metastatic colon cancer: a randomised trial 显示文摘 | Lacy AM Garc f a-Valdecasas JC Delgado S | 2002 | Lancet2002，359，9325： | 1 |
| 11 | Utilization of sugar cane baggasse hemicellulose hydrolysate by Pichia stipitis for the production of ethanol显示文摘 | Roberto I C Lacis L S Barbosa M F S | 1991 | Proc Biochem1991，26，1： | 1 |
| 12 | Lenalidomide plus dexamethasone versus thalidomide plus dexamethasone in newly diagnosed multiple myeloma: a comparative analysis of 411 patients显示文摘 | Gay F Hayman SR Lacy MQ | 2010 | Blood2010，115，7： | 1 |
| 13 | Plasma hy-drogen production in human essential hypertension: roleof heredity gender, and ethnicity 显示文摘 | Lacy F Kailasam MT O’Connor DT | 2000 | Hypertension2000，36，5： | 1 |
| 14 | The Bayesian Detection of Discontinuities in a Polynomial Regression and Its Application to the Cycle-Slip Problem显示文摘 | DE LACY M C REGUZZONI M SANSòF | 2008 | Journal of Geodesy2008，82，9： | 1 |
| 15 | The Bayesian detection of discontinuities in a polynomial regression and its application to the cycle slip problem显示文摘 | de Lacy M C Reguzzoni M Sanso F | 2008 | Journal of Geodesy2008，82，： | 1 |
| 16 | Diagnostic criteria in IBS: useful or not显示文摘 | Mearin F Lacy BE | 2012 | Neu- rogastroenterol Motil2012，24，9： | 1 |
| 17 | Plasma hydrogen peroxide production in hypertensives and normotensive subjects at genetics risk of hypertension显示文摘 | Lacy F O'connor DT Schimid-Schonbien GW | 1998 | J Hypertens1998，16，3： | 1 |
| 18 | Plasma hydrogen peroxide production in human essential hypertension:role of heredity,gender,and ethnicity显示文摘 | LACY F KAILASAM M T O′CONNOR D T | 2000 | Hypertension2000，36，5： | 1 |
| 19 | Lenalidomide plus dexmnethasone versus thalidomide plus dexamethasone in newly diagnosed muhiple ruyeloma: a comparative analysis of 411 patients 显示文摘 | Gay F Hayman SR Lacy MQ | 2010 | Blood2010，115，： | 1 |
| 20 | Enhanced free cholesterol,SREBP-2 and StAR expression in human NASH显示文摘 | Caballero F Fernández A De Lacy AM | | 0，，： | 1 |
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