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| 1 | 2018 Chinese Pediatric Cardiology Society(CPCS) guideline for diagnosis and treatment of syncope in children and adolescents显示文摘Syncope belongs to the transient loss of consciousness(TLOC), characterized by a rapid onset, short duration, and spontaneous complete recovery. It is common in children and adolescents, accounting for 1% to 2% of emergency department visits.Recurrent syncope can seriously affect children's physical and mental health, learning ability and quality of life and sometimes cardiac syncope even poses a risk of sudden death. The present guideline for the diagnosis and treatment of syncope in children and adolescents was developed for guiding a better clinical management of pediatric syncope. Based on the globally recent development and the evidence-based data in China, 2018 Chinese Pediatric Cardiology Society(CPCS) guideline for diagnosis and treatment of syncope in children and adolescents was jointly prepared by the Pediatric Cardiology Society, Chinese Pediatric Society, Chinese Medical Association(CMA)/Committee on Pediatric Syncope, Pediatricians Branch, Chinese Medical Doctor Association(CMDA)/Committee on Pediatric Cardiology, Chinese College of Cardiovascular Physicians, Chinese Medical Doctor Association(CMDA)/Pediatric Cardiology Society, Beijing Pediatric Society, Beijing Medical Association(BMA). The present guideline includes the underlying diseases of syncope in children and adolescents, the diagnostic procedures, methodology and clinical significance of standing test and headup tilt test, the clinical diagnosis vasovagal syncope, postural orthostatic tachycardia syndrome, orthostatic hypotension and orthostatic hypertension, and the treatment of syncope as well as follow-up. | Cheng Wang Yaqi Li Ying Liao Hong Tian Min Huang Xiangyu Dong Lin Shi Jinghui Sun Hongfang Jin Junbao Du Jindou An Jie Chen Mingwu Chen Qi Chen Sun Chen Yonghong Chen Zhi Chen Adolphus Kai-tung Chau Junbao Du Zhongdong Du Junkai Duan Hongyu Duan Xiangyu Dong Lin Feng Lijun Fu Fangqi Gong Yonghao Gui Ling Han Zhenhui Han Bing He Zhixu He Xiufen Hu Yimin Hua Guoying Huang Min Huang Ping Huang Yujuan Huang Hongfang Jin Mei Jin Bo Li Fen Li Tao Li Xiaohui Li Xiaoyan Liu Yan Li Haitao Lv Tiewei Lv Zipu Li Luyi Ma Silin Pan Yusheng Pang Hua Peng Yuming Qin Jie Shen Lin Shi Kun Sun Jinghui Sun Hong Tian Jie Tian Cheng Wang Hong Wang Lei Wang Jinju Wang Wendi Wang Yuli Wang Rongzhou Wu Tianhe Xia Yanyan Xiao Chunhong Xie Yanlin Xing Zhenyu Xiong Baoyuan Xu Yi Xu Hui Yan Shiwei Yang Qijian Yi Xia Yu Xianyi Yu Yue Yuan Hongyan Zhang Huili Zhang Li Zhang Qingyou Zhang Xi Zhang Yanmin Zhang Zhiwei Zhang Cuifen Zhao Bin Zhou Hua Zhu | 2018 | Science Bulletin2018，63，23： | 54 |
| 2 | Self-microemulsifying drug delivery system for improving the bioavailability of huperzine A by lymphatic uptake显示文摘Huperzine A(Hup-A) is a poorly water-soluble drug with low oral bioavailability. A selfmicroemulsifying drug delivery system(SMEDDS) was used to enhance the oral bioavailability and lymphatic uptake and transport of Hup-A. A single-pass intestinal perfusion(SPIP) technique and a chylomicron flow-blocking approach were used to study its intestinal absorption, mesenteric lymph node distribution and intestinal lymphatic uptake. The value of the area under the plasma concentration–time curve(AUC) of Hup-A SMEDDS was significantly higher than that of a Hup-A suspension(P <0.01).The absorption rate constant(K_a) and the apparent permeability coefficient(P_(app)) for Hup-A in different parts of the intestine suggested a passive transport mechanism, and the values of K_a and P_(app) of Hup-A SMEDDS in the ileum were much higher than those in other intestinal segments. The determination of Hup-A concentration in mesenteric lymph nodes can be used to explain the intestinal lymphatic absorption of Hup-A SMEDDS. For Hup-A SMEDDS, the values of AUC and maximum plasma concentration(C_(max)) of the blocking model were significantly lower than those of the control model(P<0.05). The proportion of lymphatic transport of Hup-A SMEDDS and Hup-A suspension were about 40% and 5%,respectively, suggesting that SMEDDS can significantly improve the intestinal lymphatic uptake and transport of Hup-A. | Fang Li Rongfeng Hu Bin Wang Yun Gui Gang Cheng Song Gao Lei Ye Jihui Tang | 2017 | Acta Pharmaceutica Sinica B2017，7，3： | 15 |
| 3 | Vitrectomy, lensectomy and silicone oil tamponade in the management of retinal detachment associated with choroidal detachment显示文摘AIM: To report the results of combined vitrectomy, lensectomy and silicone oil (SO) tamponade in treating primary rhegmatogenous retinal detachment (RRD) associated with choroidal detachment (CD). · METHODS: A retrospective, consecutive and case series study of 21 subjects with concurrent RRD associated with CD was conducted. All subjects underwent a standard three -port 20G pars plana vitrectomy (PPV) with lensectomy and silicone oil tamponade. Mean follow -up time was 8 months (rang from 4 to 19 months). The primary and final anatomic success rate, visual acuity and final intraocular pressure (IOP) were recorded and analyzed. ·RESULTS: Of 21 subjects, 8 were women and 13 were men. Age at presentation ranged from 22 to 75 years (mean 57.4 years). The presenting vision ranged from light perception to 0.15. The initial IOP ranged from 3mmHg to 12mmHg (mean 6.2mmHg). All eyes were phakic except one pseudophakic. No intraocular lens was implanted during the primary surgical intervention. Fifteen of 21 (71.4%) eyes had retina reattached after one operation. Six eyes had recurrent inferior retinal detachment due to proliferation. Five of them were successfully reattached after one or more additional operations. Mean IOP at final follow -up was 15.2mmHg (range from 8mmHg to 20mmHg). One case declined for further operation. The final reattachment rate was 95.2%. Visual acuity improved in 19 (90.5%) eyes, was unchanged in 1 (4.8%) eye and decreased in 1 (4.8%) eye.·CONCLUSION: Combination of vitrectomy, lensectomy and silicone tamponade is an effective method in treating RRD associated with CD, reducing the incidence of postoperative hypotony. | Jun-Min Gui Li Jia Lei Liu Jian-Di Liu | 2013 | International Journal of Ophthalmology(English edition)2013，6，3： | 14 |
| 4 | Antioxidant and Anti-inflammatory Capacity of Ferulic Acid Released from Wheat Bran by Solid-state Fermentation of Aspergillus niger显示文摘Objective A strain of Aspergillus niger(A. niger), capable of releasing bound phenolic acids from wheat bran, was isolated. This strain was identified by gene sequence identification. The antioxidant and anti-inflammatory capacity of ferulic acid released from wheat bran by this A. niger strain(FA-WB) were evaluated. Methods Molecular identification techniques based on PCR analysis of specific genomic sequences were conducted; antioxidant ability was examined using oxygen radical absorbance capacity(ORAC), cellular antioxidant activity(CAA) assays, and erythrocyte hemolysis assays. RAW264.7 cells were used as a model to detect anti-inflammatory activity. Results The filamentous fungal isolate was identified to be A. niger. ORAC and CAA assay showed that FA-WB had better antioxidant activity than that of the ferulic acid standard. The erythrocyte hemolysis assay results suggested that FA-WB could attenuate AAPH-induced oxidative stress through inhibition of reactive oxy gen species(ROS) generation. FA-WB could significantly restore the AAPH-induced increase in intracellular antioxidant enzyme activities to normal levels as well as inhibit the intracellular malondialdehyde formation. TNF-?, IL-6, and NO levels indicated that FA-WB can inhibit the inflammation induced by lipopolysaccharide(LPS). Conclusion Ferulic acid released from wheat bran by a new strain of A. niger had good anti-inflammatory activity and better antioxidant ability than standard ferulic acid. | YIN Zhi Na WU Wen Jia SUN Chong Zhen LIU Hui Fan CHEN Wen Bo ZHAN Qi Ping LEI Zhuo Gui XIN Xuan MA Juan Juan YAO Kun MIN Tian ZHANG Meng Meng WU Hui | 2019 | Biomedical and Environmental Sciences2019，32，1： | 14 |
| 5 | Hydraulic design and pre-whirl regulation law of inlet guide vane for centrifugal pump显示文摘A new hydraulic design method of three-dimensional guide vane for centrifugal pump is proposed on the assumption that the fluid at the outlet of guide vane satisfies the uniform velocity moment condition.The geometry of blade is controlled by the distributed rule of blade angles along the meridional streamline which is described by a fourth-order polynomial.Experiment results demonstrate that the designed guide vane can overcome the drawback of two-dimensional guide vane,enlarge the high efficiency scope and improve the hydraulic performance of centrifugal pump on the off-design operation conditions.In comparison with the performance of the centrifugal pump without inlet guide vane,the peak value of efficiency can be enhanced by 2.13% after the three-dimensional guide vane was being installed.The three-dimensional entire flow field of the centrifugal pump with inlet guide vane is simulated,and the basic principle and mechanism of inlet guide vane pre-whirl regulation are analyzed.The validity of design method has been proved. | TAN Lei ,CAO ShuLiang&GUI ShaoBo State Key Laboratory of Hydroscience and Engineering,Department of Thermal Engineering,Tsinghua University,Beijing 100084,China | 2010 | Science China(Technological Sciences)2010，53，8： | 14 |
| 6 | Relationship between autophagy and perineural invasion, clinicopathological features, and prognosis in pancreatic cancer显示文摘AIM To investigate the relationship between autophagy and perineural invasion(PNI), clinical features, and prognosis in patients with pancreatic cancer. METHODS Clinical and pathological data were retrospectively collected from 109 patients with pancreatic ductal adenocarcinoma who underwent radical resection at the First Affiliated Hospital of Zhengzhou University from January 2011 to August 2016. Expression levels of the autophagy-related protein microtubuleassociated protein 1 A/1 B-light chain 3(LC3) and PNI marker ubiquitin carboxy-terminal hydrolase(UCH) in pancreatic cancer tissues were detected by immunohistochemistry. The correlations among LC3 expression, PNI, and clinical pathological features in pancreatic cancer were analyzed. The patients were followed for further survival analysis. RESULTS In 109 cases of pancreatic cancer, 68.8%(75/109) had evidence of PNI and 61.5%(67/109) had high LC3 expression. PNI was associated with lymph node metastasis, pancreatitis, and CA19-9 levels(P < 0.05). LC3 expression was related to lymph node metastasis(P < 0.05) and was positively correlated with neural invasion(P < 0.05, r = 0.227). Multivariate logistic regression analysis indicated that LC3 expression, lymph node metastasis, pancreatitis, and CA19-9 level were factors that influenced neural invasion, whereas only neural invasion itself was an independent factor for high LC3 expression. Univariate analysis showed that LC3 expression, neural invasion, and CA19-9 level were related to the overall survival of pancreatic cancer patients(P < 0.05). Multivariate COX regression analysis indicated that PNI and LC3 expression were independent risk factors for poor prognosis in pancreatic cancer(P < 0.05). CONCLUSION PNI in patients with pancreatic cancer is positively related to autophagy. Neural invasion and LC3 expression are independent risk factors for pancreatic cancer with a poor prognosis. | Yan-Hui Yang Jiang-Bo Liu Yang Gui Liang-Liang Lei Shui-Jun Zhang | 2017 | World Journal of Gastroenterology2017，23，40： | 13 |
| 7 | Identification of a Newly Isolated Getah Virus in the China-Laos Border,China显示文摘In this study, we isolated a virus strain(YN12031) from specimens of Armigeres subalbatus collected in the China-Laos border. BHK-21 cells infected with YN12031 exhibited an evident cytopathic effect(CPE) 32 h post-infection. The virus particles were spherical, 70 nm in diameter, and enveloped; they also featured surface fibers. Molecular genetic analysis revealed that YN12031 was closely related to alpha viruses such as Chikungunya virus and Sindbis virus, and located in the same clade as MM2021, the prototype of Getahvirus(GETV) isolated in Malaysia in 1955. Phylogenetic analysis of the E2 and capsid genes further revealed that YN12031 was located in the same clade as the Russian isolate LEIV/16275/Mag. Analysis of the homology of nucleotides and amino acids in the coding area and E2 gene demonstrated that the YN12031 isolated from the China-Laos border(tropical region) was related closest to the LEIV/16275/Mag isolate obtained in Russia(North frigid zone area) among other isolates studied. These results suggest that GETV can adapt to different geographical environments to propagate and evolve. Thus, strengthening the detection and monitoring of GETV and its related diseases is very crucial. | LI Yuan Yuan FU Shi Hong GUO Xiao Fang LEI Wen Wen LI Xiao Long SONG Jing Dong CAO Lei GAO Xiao Yan LYU Zhi HE Ying WANG Huan Yu REN Xiao Jie ZHOU Hong Ning WANG Gui Qin LIANG Guo Dong | 2017 | Biomedical and Environmental Sciences2017，30，3： | 12 |
| 8 | A novel phenylpropanoid glycoside from Callicarpa kwangtungensis Chun显示文摘新奇 phenylpropanoid glycoside, Callicarposide A 从 Callicarpa kwangtungensis Chun 的天线部分被孤立。化学结构被阐明根据光谱分析。 | Er Lei Xie Guo Ping Zhou Teng Fei Ji Jun Wu Gui Ping Yuan | 2009 | Chinese Chemical Letters2009，20，7： | 8 |
| 9 | Association of Overlapped and Un-overlapped Comorbidities with COVID-19 Severity and Treatment Outcomes: A Retrospective Cohort Study from Nine Provinces in China显示文摘Objective Several COVID-19 patients have overlapping comorbidities. The independent role of each component contributing to the risk of COVID-19 is unknown, and how some non-cardiometabolic comorbidities affect the risk of COVID-19 remains unclear.Methods A retrospective follow-up design was adopted. A total of 1,160 laboratory-confirmed patients were enrolled from nine provinces in China. Data on comorbidities were obtained from the patients’ medical records. Multivariable logistic regression models were used to estimate the odds ratio(OR) and 95% confidence interval(95% CI) of the associations between comorbidities(cardiometabolic or non-cardiometabolic diseases), clinical severity, and treatment outcomes of COVID-19.Results Overall, 158(13.6%) patients were diagnosed with severe illness and 32(2.7%) had unfavorable outcomes. Hypertension(2.87, 1.30–6.32), type 2 diabetes(T2 DM)(3.57, 2.32–5.49),cardiovascular disease(CVD)(3.78, 1.81–7.89), fatty liver disease(7.53, 1.96–28.96), hyperlipidemia(2.15, 1.26–3.67), other lung diseases(6.00, 3.01–11.96), and electrolyte imbalance(10.40, 3.00–26.10)were independently linked to increased odds of being severely ill. T2 DM(6.07, 2.89–12.75), CVD(8.47,6.03–11.89), and electrolyte imbalance(19.44, 11.47–32.96) were also strong predictors of unfavorable outcomes. Women with comorbidities were more likely to have severe disease on admission(5.46,3.25–9.19), while men with comorbidities were more likely to have unfavorable treatment outcomes(6.58, 1.46–29.64) within two weeks.Conclusion Besides hypertension, diabetes, and CVD, fatty liver disease, hyperlipidemia, other lung diseases, and electrolyte imbalance were independent risk factors for COVID-19 severity and poor treatment outcome. Women with comorbidities were more likely to have severe disease, while men with comorbidities were more likely to have unfavorable treatment outcomes. | MA Yan ZHU Dong Shan CHEN Ren Bo SHI Nan Nan LIU Si Hong FAN Yi Pin WU Gui Hui YANG Pu Ye BAI Jiang Feng CHEN Hong CHEN Li Ying FENG Qiao GUO Tuan Mao HOU Yong HU Gui Fen HU Xiao Mei HU Yun Hong HUANG Jin HUANG Qiu Hua HUANG Shao Zhen JI Liang JIN Hai Hao LEI Xiao LI Chun Yan LI Min Qing LI Qun Tang LI Xian Yong LIU Hong De LIU Jin Ping LIU Zhang MA Yu Ting MAO Ya MO Liu Fen NA Hui WANG Jing Wei SONG Fang Li SUN Sheng WANG Dong Ting WANG Ming Xuan WANG Xiao Yan WANG Yin Zhen WANG Yu Dong WU Wei WU Lan Ping XIAO Yan Hua XIE Hai Jun XU Hong Ming XU Shou Fang XUE Rui Xia YANG Chun YANG Kai Jun YUAN Sheng Li ZHANG Gong Qi ZHANG Jin Bo ZHANG Lin Song ZHAO Shu Sen ZHAO Wan Ying ZHENG Kai ZHOU Ying Chun ZHU Jun Teng ZHU Tian Qing ZHANG Hua Min WANG Yan Ping WANG Yong Yan 无 | 2020 | Biomedical and Environmental Sciences2020，33，12： | 8 |
| 10 | Controllability of an underactuated spacecraft with one thruster under disturbance显示文摘For an underactuated spacecraft using only one thruster,the attitude controllability with respect to the orbit frame is studied in the presence of periodical oscillation disturbance,which provides a preconditional guide on designing control law for underactuated attitude control system.Firstly,attitude dynamic model was established for an underactuated spacecraft,and attitude motion was described using the special orthogonal group(SO(3)).Secondly,Liouville theorem was used to confirm that the flow generated by the drift vector of the underactuated attitude control system is volume-preserving.Furthermore,according to Poincare''s recurrence theorem,we draw conclusions that this drift field is weakly positively poisson stable(WPPS).Thirdly,the sufficient and necessary condition of controllability was obtained on the basis of lie algebra rank condition(LARC).Finally,the controllable conditions were analyzed and simulated in different cases of inertia matrix with the installed position of thruster. | Dong-Xia Wang Ying-Hong Jia Lei Jin Hai-Chao Gui Shi-Jie Xu | 2012 | Acta Mechanica Sinica2012，28，3： | 6 |
| 11 | Development and application of Baosteel X80 large diameter UOE longitudinal submerged arc welded pipes显示文摘With the increase in energy demand,the demand for oil and gas transmission pipes,particularly high-grade longitudinal submerged arc welded pipes (LSAWs),have been growing in recent years.The construction of the 2nd West-East natural gas transmission pipeline project shows that the oil and gas pipeline construction has entered a new phase of development with X80 pipes being applied in large scales for the first time in China.This paper briefly introduces the 2nd West-East natural gas transmission pipeline project and its main technical requirements with the focus on the features of API standard 5L X80 grade 1219 mm series of U-ing-O-ing-Expanding (UOE) LSAW pipes,which Baosteel developed with the integrated technology for the 2nd West-East natural gas transmission pipeline project.The analysis shows the extra-low carbon content,the high contents of manganese and niobium,the fine microstructure,the high strength,the toughness and the good weldability of X80 pipes meet the requirements of 'the technical specification of LSAW linepipes for the 2nd West-East natural gas transmission pipeline project in China'.By the end of June 2010,Baosteel had totally produced 322000 t of 1219 mm X80 UOE steel pipes,which have been successfully used in the 2nd West-East natural gas transmission pipeline project,thus filling the gap of the production of large diameter X80 UOE LSAW pipes in China. | XIE Shiqiang GUI Guangzheng ZHENG Lei | 2010 | Baosteel Technical Research2010，4，3： | 6 |
| 12 | Clinical Characteristics of Hospitalized Patients with SARS-CoV-2 and Hepatitis B Virus Co-infection显示文摘Dear Editor,Coronavirus disease 2019(COVID-19)is a global pandemic caused by severe acute respiratory syndrome coronavirus 2(SARS-Co V-2).SARS-Co V-2 infection was first detected in Wuhan,China in late December 2019.The virus was spreading rapidly to other cities of China and accumulating cases had been reported(Li et al.2020). | Xiaoping Chen Qunqun Jiang Zhiyong Ma Jiaxin Ling Wenjia Hu Qian Cao Pingzheng Mo Lei Yao Rongrong Yang Shicheng Gao Xien Gui Wei Hou Yong Xiong Jinlin Li Yongxi Zhang | 2020 | Virologica Sinica2020，35，6： | 6 |
| 13 | Assessment of Iron Bioavailability in Ten Kinds of Chinese Wheat Flours Using an in vitro Digestion/Caco-2 cell Model显示文摘Objective To compare iron bioavailability (Fe BV) from ten selected kinds of Chinese wheat flours in order to provide scientific basis for further human trials and enable plant breeding programs to screen biofortified wheat cultivars. Methods An in vitro digestion/Caco-2 cell model was used to assess Fe BV of ten flour samples from six leading Chinese wheat cultivars and the stability of Fe BV in one cultivar was studied across three growing environments. Results Significant differences were observed in both Fe BV and Fe bioavailability per gram of food (Fe BVPG) among cultivars (P<0.01) grown at the same location with the same flour extraction rate. Zhongyou 9507 and Jingdong 8 had Fe BV 37%-54% and Fe BVPG 103%-154% higher than the reference control. In the Anyang environment, Zhongyou 9507 had a higher wheat flour-Fe level and Fe BVPG. Differences in Fe BV were detected in cultivars with different flour extraction rates. Conclusion Zhongyou 9507 and Jingdong 8 were identified as the most promising cultivars for further evaluation of efficacy by using human subjects. The growing environments had no effect on Fe BV, but did have a significant effect on Fe BVPG. Fe bioavailabilities in low-extraction (40%) flours were higher than those in high-extraction (78%) flours. | LEI Ji ZHANG Yong CHEN Xiang Gui ZHANG Ming Qiu BAI Lin HUANG Cheng Yu Ortiz Monasterio IVAN | 2012 | Biomedical and Environmental Sciences2012，25，5： | 5 |
| 14 | Local controllability and stabilization of spacecraft attitude by two single-gimbal control moment gyros显示文摘The attitude control problem of a spacecraft underactuated by two single-gimbal control moment gyros(SGCMGs) is investigated.Small-time local controllability(STLC) of the attitude dynamics of the spacecraft-SGCMGs system is analyzed via nonlinear controllability theory.The conditions that guarantee STLC of the spacecraft attitude by two non-coaxial SGCMGs are obtained with the momentum of the SGCMGs as inputs,implying that the spacecraft attitude is STLC when the total angular momentum of the whole system is zero.Moreover,our results indicate that under the zero-momentum restriction,full attitude stabilization is possible for a spacecraft using two non-coaxial SGCMGs.For the case of two coaxial SGCMGs,the STLC property of the spacecraft cannot be determined.In this case,an improvement to the previous full attitude stabilizing control law,which requires zero-momentum presumption,is proposed to account for the singularity of SGCMGs and enhance the steady state performance.Numerical simulation results demonstrate the effectiveness and advantages of the new control law. | Gui Haichao Jin Lei Xu Shijie | 2013 | Chinese Journal of Aeronautics2013，26，5： | 5 |
| 15 | Changes in sea ice kinematics in the Arctic outflow region and their associations with Arctic Northeast Passage accessibility显示文摘Amplification of climate warming in the Arctic is causing a dramatic retreat of sea ice, which means the Arctic sea routes are becoming increasingly accessible. This study used a satellite-derived sea ice motion product to quantify the kinematic features of sea ice in the Arctic outflow region which specially referred to the Fram Strait and to the north of the Northeast Passage(NEP). An observed trend of increased southward sea ice displacement from the central Arctic to the Fram Strait indicated enhancement of the Transpolar Drift Stream(TDS). In the regions to the north of the NEP, the long-term trend of northward sea ice speed in the Kara sector was +0.04 cm/s per year in spring. A significant statistical relationship was found between the NEP open period and the northward speed of the sea ice to the north of the NEP. The offshore advection of sea ice could account for the opening of sea routes by 33% and 15% in the Kara and Laptev sectors, respectively. The difference in sea level pressure across the TDS,i.e., the Central Arctic Index(CAI), presented more significant correlation than for the Arctic atmospheric Dipole Anomaly index with the open period of the NEP, and the CAI could explain the southward displacement of sea ice toward the Fram Strait by more than 45%. The impact from the summer positive CAI reinforces the thinning and mechanical weakening of the sea ice in the NEP region, which improves the navigability of the NEP. | Dawei Gui Xiaoping Pang Ruibo Lei Xi Zhao Jia Wang | 2019 | Acta Oceanologica Sinica2019，38，8： | 5 |
| 16 | Ladder-like metal oxide nanowires: Synthesis, electrical transport, and enhanced light absorption properties显示文摘 | Bo Liang Hongtao Huang Zhe Liu Gui Chen Gang Yu Tao Luo Lei Liao Di Chen Guozhen Shen | 2014 | Nano Research2014，7，2： | 4 |
| 17 | Analysis of Malware Application Based on Massive Network Traffic显示文摘Security and privacy issues are magnified by velocity, volume, and variety of big data. User's privacy is an even more sensitive topic attracting most people's attention. While XcodeGhost, a malware of i OS emerging in late 2015, leads to the privacy-leakage of a large number of users, only a few studies have examined XcodeGhost based on its source code. In this paper we describe observations by monitoring the network activities for more than 2.59 million i Phone users in a provincial area across 232 days. Our analysis reveals a number of interesting points. For example, we propose a decay model for the prevalence rate of Xcode Ghost and we find that the ratio of the infected devices is more than 60%; that a lot of popular applications, such as Wechat, railway 12306, didi taxi, Youku video are also infected; and that the duration as well as the traffic volume of most Xcode Ghost-related HTTP-requests is similar with usual HTTP-request which makes it difficult to be found. Besides, we propose a heuristic model based on fingerprint and its web-knowledge to identify the infected applications. The identifying result shows the efficiency of this model. | Xiaolin Gui Jun Liu Mucong Chi Chenyu Li Zhenming Lei | 2016 | China Communications2016，13，8： | 4 |
| 18 | Bone Loss Induced by Simulated Microgravity,Ionizing Radiation and/or Ultradian Rhythms in the Hindlimbs of Rats显示文摘Objective To better understand the pathological causes of bone loss in a space environment, including microgravity, ionizing radiation, and ultradian rhythms. Methods Sprague Dawley(SD) rats were randomly divided into a baseline group, a control group, a hindlimb suspension group, a radiation group, a ultradian rhythms group and a combined-three-factor group. After four weeks of hindlimb suspension followed by X-ray exposure and/or ultradian rhythms, biomechanical properties, bone mineral density, histological analysis, microstructure parameters, and bone turnover markers were detected to evaluate bone loss in hindlimbs of rats. Results Simulated microgravity or combined-three factors treatment led to a significant decrease in the biomechanical properties of bones, reduction in bone mineral density, and deterioration of trabecular parameters. Ionizing radiation exposure also showed adverse impact while ultradian rhythms had no significant effect on these outcomes. Decrease in the concentration of the turnover markers bone alkaline phosphatase(b ALP), osteocalcin(OCN), and tartrate-resistant acid phosphatase-5 b(TRAP-5 b) in serum was in line with the changes in trabecular parameters. Conclusion Simulated microgravity is the main contributor of bone loss. Radiation also results in deleterious effects but ultradian rhythms has no significant effect. Combined-three factors treatment do not exacerbate bone loss when compared to simulated microgravity treatment alone. | ZHANG Ya Nan SHI Wen Gui LI He HUA Jun Rui FENG Xiu WEI Wen Jun WANG Ju Fang HE Jin Peng LEI Su Wen | 2018 | Biomedical and Environmental Sciences2018，31，2： | 4 |
| 19 | Optimal Static Partition Configuration in ARINC653 System显示文摘ARINC653 systems, which have been widely used in avionics industry, are an important class of safety-critical applications. Partitions are the core concept in the Arinc653 system architecture. Due to the existence of partitions, the system designer must allocate adequate time slots statically to each partition in the design phase. Although some time slot allocation policies could be borrowed from task scheduling policies, no existing literatures give an optimal allocation policy. In this paper, we present a partition configuration policy and prove that this policy is optimal in the sense that if this policy fails to configure adequate time slots to each partition, nor do other policies. Then, by simulation, we show the effects of different partition configuration policies on time slot allocation of partitions and task response time, respectively. | Sheng-Lin Gui Lei Luo Sen-Sen Tang Yang Meng | 2011 | Journal of Electronic Science and Technology2011，9，4： | 4 |
| 20 | Agent-oriented Aid-modeling for the Distributed Activity Network | DENG Gui\|shi\+1,\ LI Wen\|lei\+1,\ O. Moeschlin\+2 1.Institute of Systems Engineering, Dalian University of Technology Dalian 116024, China 2.Department of Mathematics, Fern University in Hagen, D 58084 Germany | 2000 | Systems Science and Systems Engineering2000，10，1： | 4 |
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