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| 1 | Prediction of urban human mobility using large-scale taxi traces and its applications显示文摘这篇论文在一个城市的出租车交通系统调查人的活动性模式。这个工作集中于预言 humanmobility fromdiscovering 模式在从城市的热点的旅客提取数量(PUQ ) 的数字。这份报纸建议改进 ARIMA 基于预言方法在一个热点预报旅客的空间时间的变化。有 4 000 出租车 GPS 的一个大规模 realworld 数据集合的评估跟踪超过一年表演一个预言错误仅仅 5.8% 。我们也探索预言途径的申请帮助司机发现他们的下位旅客。用历史的真实世界的数据的模拟结果证明与我们的指导,驱动程序能减少花的时间,距离旅行,到发现他们的下位旅客在 37.1% 和 6.4% ,分别地。 | Xiaolong LI Gang PAN Zhaohui WU Guande QI Shijian LI Daqing ZHANG Wangsheng ZHANG Zonghui WANG | 2012 | Frontiers of Computer Science2012，6，1： | 45 |
| 2 | From a single network to a network of networks显示文摘Network science has atracted much atention in recent years due to its interdisciplinary applications. We witnessed the revolution of network science in 1998 and 1999 started with small-world and scale-free networks having now thousands of high-proile publications, and it seems that since 2010 studies of‘network of networks'(NON), sometimes called multilayer networks or multiplex, have atracted more and more atention. he analytic framework for NON yields a novel percolation law for n interdependent networks that shows that percolation theory of single networks studied extensively in physics and mathematics in the last 50 years is a speciic limit of the rich and very diferent general case of n coupled networks. Since then, properties and dynamics of interdependent and interconnected networks have been studied extensively, and scientists are inding many interesting results and discovering many surprising phenomena. Because most natural and engineered systems are composed of multiple subsystems and layers of connectivity, it is important to consider these features in order to improve our understanding of such complex systems. Now the study of NON has become one of the important directions in network science.In this paper, we review recent studies on the new emerging area—NON. Due to the fast growth of this ield, there are many deinitions of diferent types of NON, such as interdependent networks,interconnected networks, multilayered networks, multiplex networks and many others. here exist many datasets that can be represented as NON, such as network of diferent transportation networks including light networks, railway networks and road networks, network of ecological networks including species interacting networks and food webs, network of biological networks including gene regulation network,metabolic network and protein–protein interacting network, network of social networks and so on. Among them, many interdependent networks including critical infrastructures are embedded in space, introducing spatial constraints. hus, we also review the progress on study of spatially embedded networks. As a result of spatial constraints, such interdependent networks exhibit extreme vulnerabilities compared with their non-embedded counterparts. Such studies help us to understand, realize and hopefully mitigate the increasing risk in NON. | Jianxi Gao Daqing Li Shlomo Havlin | 2014 | National Science Review2014，1，3： | 15 |
| 3 | On a New Genus of Basal Neoceratopsian Dinosaur from the Early Cretaceous of Gansu Province, China显示文摘A new genus and species of basal neoceratopsian dinosaur, Auroraceratops rugosus, is reported based on material from the Early Cretaceous Xinminpu Group in the Gongpoquan Basin of Gansu Province, China. Auroraceratops is represented by a nearly complete skull and low jaws, and different greatly from all other neoceratopsians by its considerable breadth of the nasals, fungiform expansion of the dorsal end of the lacrimal, highly developed rugosity of the jugal, dentary and surangular, and inflated, striated premaxillary teeth. The finding of Auroraceratops adds diversity and helps elucidate the evolution of basal neoceratopsian dinosaurs. | YOU Hailu LI Daqing JI Qiang Matthew C. LAMANNA Peter DODSON | 2005 | Acta Geologica Sinica(English Edition)2005，79，5： | 13 |
| 4 | A New Hadrosauriform Dinosaur from the Early Cretaceous of Gansu Province,China显示文摘一条新基础 hadrosauriform 恐龙, Xuwulong yueluni 情报。et sp。nov,包括完全的头盖骨,几乎完全的轴的骨骼,和完全的左骨盆的腰带基于一个明白表示的标本被报导。标本在 Jiuquan 区域从早白垩纪 Yujingzi 盆被恢复,西北的中国的 Gansu 省。Xuwulong 在之中最 hadrosauriform 恐龙的基础成员,并且在在侧面的看法和铺平与的 mandible 的关节的表面有齿骨的塑造 V 的喙的结束由它的唯一的更低的颚区分了齿骨分支中间高度,以及一扩大并且 downturned prepubic 过程。包括 Xuwulong,三基础 hadrosauriforms 在 Mazongshan 区域从早白垩纪 Xinminpu 组被发现了,成为学习起源和 duck-billed 恐龙的早进化是一个重要区域。 | YOU Hailu LI Daqing LIU Weichang | 2011 | Acta Geologica Sinica(English Edition)2011，85，1： | 8 |
| 5 | On error distance of Reed-Solomon codes显示文摘The complexity of decoding the standard Reed-Solomon code is a well known open prob-lem in coding theory. The main problem is to compute the error distance of a received word. Using the Weil bound for character sum estimate, we show that the error distance can be determined precisely when the degree of the received word is small. As an application of our method, we give a significant improvement of the recent bound of Cheng-Murray on non-existence of deep holes (words with maximal error distance). | LI YuJuan WAN DaQing | 2008 | Science China Mathematics2008，51，11： | 8 |
| 6 | A drug from poison:how the therapeutic effect of arsenic trioxide on acute promyelocytic leukemia was discovered显示文摘It is surprising that,while arsenic trioxide(ATO) is now considered as 'the single most active agent in patients with acute promyelocytic leukemia(APL)',the most important discoverer remains obscure and his original papers have not been cited by a single English paper.The discovery was made during the Cultural Revolution when most Chinese scientists and doctors struggled to survive.Beginning with recipes from a countryside practitioner that were vague in applicable diseases,Zhang TingDong and colleagues proposed in the 1970s that a single chemical in the recipe is most effective and that its target is APL.More than 20 years of work by Zhang and colleagues eliminated the confusions about whether and how ATO can be used effectively.Other researchers,first in China and then in the West,followed his lead.Retrospective analysis of data from his own group proved that APL was indeed the most sensitive target.Removal of a trace amount of mercury chloride from the recipe by another group in his hospital proved that only ATO was required.Publication of Western replication in 1998 made the therapy widely accepted,though neither Western,nor Chinese authors of English papers on ATO cited Zhang's papers in the 1970s.This article focuses on the early papers of Zhang,but also suggests it worth further work to validate Chinese reports of ATO treatment of other cancers,and infers that some findings published in Chinese journals are of considerable value to patients and that doctors from other countries can benefit from the clinical experience of Chinese doctors with the largest population of patients. | RAO Yi LI RunHong ZHANG DaQing | 2013 | Science China(Life Sciences)2013，56，6： | 7 |
| 7 | Fault Systems and Their Mechanisms of the Formation and Distribution of the Tarim Basin,NW China显示文摘This article aims to analyze the main controlling factors of development,distribution and evolution of the fault systems in the Tarim Basin.Based on the seismic profile interpretation,comprehensive analysis of the drilling and geologic data,six fault systems maybe recognized in the Tarim Basin,they are the foreland fault system of the South Tianshan Mountain,the northern Tarim uplift fault system,North Tarim depression fault system,central fault system,Southwest Tarim fault system,and Southeast Tarim fault system.It is indicated that the main differences exist at the development,evolution and distribution of the fault systems in the Tarim Basin.The sub-fault systems can be recognized according to the differences of the fault development and distribution in the interior of the fault system.It is characterized that the multi-level differential development and distribution of the fault systems exist in the Tarim Basin.The fault belt developed in the Paleozoic strata mainly distribute at the paleo-uplift and paleo-slope in the interior of the Tarim Basin,and the fault belt occurred in the Meso–Cenozoic beds mainly develop at the peripheral foreland depressions.Zonal and segment differential development and distribution of the fault systems also exist in the Tarim Basin.The formation and distribution of the Tarim fault systems is of complex controlling mechanisms.Poly-phase structural movement and tectonic transition controls the multi-phase differential development and distribution of the fault systems in the Tarim Basin.Multi-level differential development and distribution is controlled by multi-level detachment belt and regional unconformities.Zonal and segment differential development and distribution of the Tarim fault systems maybe controlled by pre-existed basement structural texture.The major direction of the fault systems in the Tarim Basin is controlled by the later stage basin-mountain coupling. | Liangjie Tang Taizhu Huang Haijun Qiu Guimei Wan Meng Li Yong Yang Daqing Xie Gang Chen | 2014 | Journal of Earth Science2014，25，1： | 6 |
| 8 | Vegfa signaling regulates diverse artery/vein formation in vertebrate vasculatures显示文摘Vascular endothelial growth factor A(Vegfa) signaling regulates vascular development during embryogenesis and organ formation.However,the signaling mechanisms that govern the formation of various arteries/veins in various tissues are incompletely understood.In this study,we utilized transcription activator-like effector nuclease(TALEN) to generate zebrafish vegfaa mutants.vegfaa^(-/-) embryos are embryonic lethal,and display a complete loss of the dorsal aorta(DA) and expansion of the cardinal vein.Activation of Vegfa signaling expands the arterial cell population at the expense of venous cells during vasculogenesis of the axial vessels in the trunk.Vegfa signaling regulates endothelial cell(EC) proliferation after arterial-venous specification.Vegfa deficiency and overexpression inhibit the formation of tip cell filopodia and interfere with the pathfinding of intersegmental vessels(ISVs).In the head vasculature,vegfaa^(-/-) causes loss of a pair of mesencephalic veins(MsVs) and central arteries(CtAs),both of which usually dvelop via sprouting angiogenesis.Our results indicate that Vegfa signaling induces the formation of the DA at the expense of the cardinal vein during the trunk vasculogenesis,and that Vegfa is required for the angiogenic formation of MsVs and CtAs in the brain.These findings suggest that Vegfa signaling governs the formation of diverse arteries/veins by distinct cellular mechanisms in vertebrate vasculatures. | Daqing Jin Diqi Zhu Yabo Fang Yiwei Chen Gaihong Yu Weijun Pan Dong Liu Fen Li Tao P.Zhong | 2017 | Journal of Genetics and Genomics2017，44，10： | 6 |
| 9 | A Decision-Making Method for Air Combat Maneuver Based on Hybrid Deep Learning Network显示文摘In this paper, a hybrid deep learning network-based model is proposed and implemented for maneuver decision-making in an air combat environment.The model consists of stacked sparse auto-encoder network for dimensionality reduction of high-dimensional,dynamic time series combat-related data and long shortterm memory network for capturing the quantitative relationship between maneuver control variables and the time series combat-related data after dimensionality reduction.This model features: using time series data as the basis of decision-making, which is more in line with the actual decision-making process;using stacked sparse auto-encoder network to reduce the dimension of time series data to predict the result more accurately;in addition, taking the maneuver control variables as the output to control the maneuver, which makes the maneuver process more flexible. The relevant experiments have demonstrated that the proposed model can effectively improve the prediction accuracy and convergence rate in the prediction of maneuver control variables. | LI Bo LIANG Shiyang CHEN Daqing LI Xitong | 2022 | Chinese Journal of Electronics2022，31，1： | 6 |
| 10 | Late stage thermal history of the Songliao Basin and its tectonic implications: Evidence from apatite fission track (AFT) analyses显示文摘Apatite Fission Track (AFT) data from the Songliao Basin indicates that the late stage tectonic movements in the Songliao Basin have zoning in space and episodes in time. The late stage tectonic movements started from the east part of the basin and migrated westward. AFT ages in the east part of the basin are older than those in the west part of the basin, suggesting that the uplift occurred earlier in the east than in the west. The denudation thickness in the east part of the basin is significantly greater than that in the centre and west. The thermal history evolved two episodes of rapid cooling and subsequent slow cooling processes. Age-depth relationship derived from the AFT data indicates a four-episode denudation history. Further Monte Carlo random simulation of the AFT data reveals the four changing points of the thermal evolution at 65 Ma, 43.5 Ma, 28 Ma and 15 Ma, respectively. The uplifting and denudation rates from different episodes of evolution are proportional to the plate convergence rate. Based on the above analyses and the regional geologic background, it is concluded that the late stage thermal events in the Songliao Basin are the far field response to the subduction of the Pacific Plate under the Eurasian Plate. The first episode of the rapid cooling probably started at the end of the Nenjiang Formation, climaxed at the end of the Cretaceous and ceased at the Late Eocene. The subsequent slow cooling lasts another 15 Ma. The first episode of the evolution is the far field response to the major episode of the Yanshan Movement and subsequent series of the tectonic reorganization, especially the directional change of the Pacific Movement and also the subduction of the Indian Plate underneath the Eurasian Plate. While the second episode of the evolution is the far field response to the extension and closure of the Sea of Japan. Extension led to the migration and converging of the mantle heat flow to the Sea of Japan and resulted in the rapid cooling of the Songliao Basin. | XIANG CaiFu1,2?, FENG ZhiQiang3, PANG XiongQi1,2, WU HeYong3 & LI JunHong1,2 1 Basin and Reservoir Research Center, China University of Petroleum, Beijing 102249, China 2 Key Laboratory for Hydrocarbon Accumulation in China University of Petroleum, Ministry of Education, Beijing 102249, China 3 Prospecting and Exploration Institute of Daqing Oil Field, Daqing 163458, China | 2007 | Science China Earth Sciences2007，50，10： | 6 |
| 11 | In vitro differentiation of human adipose-derived mesenchymal stem cells into endothelial-like cells显示文摘The neovascularization of ischemic tis- sue is a crucial initial step for the functional rehabili- tation and wound healing. However, the short of seed cell candidate for the foundation of vascular network is still a big issue. Human adipose tissue derived mesenchymal stem cells (hADSCs), which possess multilineage potential, are capable of adipogenic, osteogenic, and chondrogenic differentiation. We examined whether this kind of stem cells could dif- ferentiate into endothelial-like cells and participate in blood vessel formation, and whether they could be used as an ideal cell source for therapeutic angio- genesis in ischemic diseases or vascularization of tissue constructs. The results showed that hADSCs, grown under appropriately induced conditions, dis- played characteristics similar to those of vessel en- dothelium. The differentiated cells expressed endo- thelial cell markers CD34 and vWF, and had high metabolism of acetylated low-density lipoprotein and prostacyclin. In addition, the induced cells were able to form tube-like structures when cultured on matrigel. Our data indicated that induced hADSCs could ex- hibit characteristics of endothelial cells. Therefore, these cells, as a source of human endothelial cells, may find many applications in such realms as engi- neering blood vessels, endothelial cell transplantation for myocardial regeneration, and induction of angio- genesis for treatment of regional ischemia. | GUAN Lidong LI Shaoqing WANG Yunfang YUE Huimin LIU Daqing HE Lijuan BAI Cixian YAN Fang NAN Xue SHI Shuangshuang PEI Xuetao | 2006 | Chinese Science Bulletin2006，51，15： | 6 |
| 12 | New progress of microbial prospecting of oil and gas in China:Taking the Satellite Oilfield in Daqing as an example显示文摘The Microbial Prospecting of Oil and Gas(MPOG) is applied to the matured development area in the Satellite Oilfield in Daqing for the first time. And with the MPOG,the hydrocarbon accumulation regulation controlled by faults is interpreted,and the matured development area is extended out to western part. At the same time,four microbial anomalies are discovered. The MPOG results were verified by the hydrocarbon-bearing conditions of the 10 drilled wells within the following half a year,and the consistent rate is up to 80%,which add about 300×104 t of the explored petroleum-in-place. Through study and successful application of MPOG to the Satellite Oilfield,the basis of the application from the exploration to development field is substantially established,and standard system of microbial anomaly is more precisely built for the Satellite Oilfield,which provided an effective explanatory item for the studied and adjacent region,even for the whole Songliao Basin,and also a new technique for complicated reservoirs,especially for the later stage development of litho-reservoirs in China. Therefore,it must have profound influence upon the oil and gas exploration,especially upon the remaining oil,extension and reserves addition of the developed area in China. | YUAN ZhiHua1,ZHANG YuQing1,ZHAO Qing1,JIANG HuFu2,LIU YunYan2,LUO ZhongHua2,LI Xue1,WANG ShiTou1,LI Bo1,PAN GuoHui2,GAO XingYou2 & ZHANG GuoLiang2 1 Geochemistry Department of Yangtze University,Key Laboratory of Oil & Gas Resource and Exploration Technique of Ministry of Education of China,Jingzhou 434023,China 2 The 8th Oil Recovery Plant of Daqing Oilfield Co. Ltd.,PetroChina,Daqing 163515,China | 2009 | Science China Earth Sciences2009，52，S1： | 5 |
| 13 | Oxide dispersion strengthened stainless steel 316L with superior strength and ductility by selective laser melting显示文摘Dense oxide dispersion strengthened(ODS) 316 L steels with different amount of Y2O3 additions were succe s s fully fabricated by selective laser melting(SLM) even though part of the added Y2O3 got lost during the process.The microstructure was characterized in details and the mechanical properties were tested at room temperature,250℃ and 400℃,respectively.The effect of the scanning speed on agglomeration of nanoparticles during SLM process was discussed.Superior properties,e.g.,yield strength of 574 MPa and elongation of 91%,were achieved at room temperature in SLM ODS 316 L with additional 1% of Y2 O3.At elevated temperature s,the strength kept high but the elongations dropped dra matically.It was observed that nano-voids nucleated throughout the whole gauge section at the sites where nanoinclusions located.The growth and coalescence of these voids were suppre s sed by the formation of an element segregation network before necking,which relieved local stress concentration and thus delayed necking.This unusual necking behavior was studied and compared to the previous theory.It appeared that the strong convection presented in the melt pool can evenly redistribute the short-time milled coarse Y2O3 precursor powder during SLM process.These findings can not only solve the problems encountered during the fabrication of ODS components but also replenish the strengthening mechanism of SLM 316 L thus pave a way for further improving of mechanical properties. | Yuan Zhong Leifeng Liu Ji Zou Xiaodong Li Daqing Cui Zhijian Shen | 2020 | Journal of Materials Science & Technology2020，42，7： | 5 |
| 14 | Entropy Production Analysis for Hump Characteristics of a Pump Turbine Model显示文摘The hump characteristic is one of the main problems for the stable operation of pump turbines in pump mode.However,traditional methods cannot reflect directly the energy dissipation in the hump region.In this paper,3D simulations are carried out using the SST k-ω turbulence model in pump mode under different guide vane openings.The numerical results agree with the experimental data.The entropy production theory is introduced to determine the flow losses in the whole passage,based on the numerical simulation.The variation of entropy production under different guide vane openings is presented.The results show that entropy production appears to be a wave,with peaks under different guide vane openings,which correspond to wave troughs in the external characteristic curves.Entropy production mainly happens in the runner,guide vanes and stay vanes for a pump turbine in pump mode.Finally,entropy production rate distribution in the runner,guide vanes and stay vanes is analyzed for four points under the 18 mm guide vane opening in the hump region.The analysis indicates that the losses of the runner and guide vanes lead to hump characteristics.In addition,the losses mainly occur in the runner inlet near the band and on the suction surface of the blades.In the guide vanes and stay vanes,the losses come from pressure surface of the guide vanes and the wake effects of the vanes.A new insight-entropy production analysis is carried out in this paper in order to find the causes of hump characteristics in a pump turbine,and it could provide some basic theoretical guidance for the loss analysis of hydraulic machinery. | LI Deyou GONG Ruzhi WANG Hongjie XIANG Gaoming WEI Xianzhu QIN Daqing | 2016 | Chinese Journal of Mechanical Engineering2016，29，4： | 4 |
| 15 | Preparation and characterization of a specialized lunar regolith simulant for use in lunar low gravity simulation显示文摘Lunar in-situ resource utilization(ISRU)has been put on the agenda by many countries.Due to the special material nature and low gravity environment,the lunar regolith demonstrates significantly different behavior from terrestrial geomaterials.However,the systematic understanding of its geotechnical behavior is now seriously restricted by the scarcity of lunar regolith and the difficulty in simulating lunar gravity.A new lunar regolith simulant,termed as China University of Mining and Technology Number One(CUMT-1),has been developed to recover properties of the lunar regolith and simulate the lunar gravity by adopting the recently advanced geotechnical magnetic-similitude-gravity model testing(GMMT)method.The CUMT-1 simulant was prepared by reproducing the in-situ formation and fragmentation of the lunar matrix,which plays a key role in the irregular particle morphology.The mineralogical compositions,particle morphology and gradation,specific gravity,bulk density,void ratio,shear strength,and compressibility were determined.After quantifying the magnetization and magnetic-similitude-gravity characteristics,an application of the cone penetration resistance under low gravity was further given.The obtained results are compared to the values known for lunar regolith samples and other simulants,which demonstrates promising characteristics for use in geotechnical engineering-based and scientificbased applications,especially considering the influence of lunar gravity. | Ruilin Li Guoqing Zhou Kang Yan Jun Chen Daqing Chen Shangyue Cai Pin-Qiang Mo | 2022 | International Journal of Mining Science and Technology2022，32，1： | 4 |
| 16 | 最大非毒性剂量汉防己甲素对人鼻咽癌细胞放疗增敏作用的研究显示文摘目的 探讨最大非毒性剂量汉防己甲素(tetrandrine,Tet)对人鼻咽癌细胞株CNE1和CNE2的放射增敏作用.方法 采用单纯放射线照射和Tet联合放射线照射对CNE1和CNE2细胞株进行处理,中性彗星电泳检测不同方式处理组中CNE1和CNE2细胞DNA损伤,流式细胞仪检测细胞周期和细胞凋亡率.结果 单纯放射线照射组CNE1和CNE2细胞平均彗星尾矩(tail moment,TM)分别为(7.13±3.70)(x±s)、(11.52±4.04),Tet联合放射线照射组平均TM分别为(13.61 ±5.45)、(18.85±6.18),差异有统计学意义(t值分别为2.784和3.089,P值均<0.05).单纯放射线照射组CNE1和CNE2细胞周期以G2期为主,分别为(42.62±2.07)%、(34.82±2.74)%,Tet联合放射线照射组分别为(17.02±1.87)%、(19.64±4.82)%,差异有统计学意义(t值分别为23.173和16.500,P值均<0.01).单纯放射线照射组CNE1和CNE2细胞凋亡率分别为(17.24%±0.99)%、(16.68%±0.27)%,Tet联合放射线照射组分别为(19.11±1.24)%、(18.51±2.41)%,差异无统计学意义(P值均>0.05).结论 最大非毒性剂量Tet能增加人鼻咽癌细胞株CNE1和CNE2的放射敏感性,其机制可能与去除放射线照射诱导的G2/M期阻滞,降低细胞修复DNA双链断裂能力有关. | 王凯 张革化 常利红 吴喜福 黎景佳 庄士民 王君 Daqing Li | 2014 | 中华耳鼻咽喉头颈外科杂志2014，49，3： | 4 |
| 17 | A Large Therizinosauroid(Dinosauria:Theropoda) from the Early Cretaceous of Northwestern China显示文摘我们此处描述 theropoddinosaur 的头部的骨骼在 Yujingzi 盆的更低的白垩纪 Xinminpu 组发现了的一根联系部分柱子,在 Gansu 省的 Jiuquanarea,西北的中国。它的肱骨展示,例如强烈扩展了近似、远侧的结束,一个很好发达的中间的有块茎,在肱骨的头部的表面上表示的远侧的髁,和 hypertrophied entepicondyle,决定性地建立标本的 thetherizinosauroid 亲密关系。它在有作为不同于另外的 therizinosauroids 使神圣,有 thedorsomedial 上的突出的圆、有条纹的肿大的糟糕界定的浅窝的窝它的肩胛部分,和耻骨出现与一强烈凹面头部的边缘。Itrepresents 新税在上, Suzhousaurus megatherioides 情报。et sp。nov。是的 Cladistic 分析 recoversSuzhousaurus 姐妹税在上 Nothronychus mckinleyi 从中间 -- 西方的 NorthAmerica 的白垩纪;一起,他们是 Therizinosauroidea 的基础成员,更多比 EarlyCretaceous Falcarius 和 Beipiaosaurus 发源,但是更少与“ Nanshiungosaurus ”比 Alxasaurus 和 Therizinosauridae.Along 发源从在 Mazongshan 区域 ofnorthern 的可能同时代的床的 bohlini --大多数 Gansu , Suzhousaurus 早代表大知道之一 Cretaceoustherizinosauroids ,证明这 clade 它的进化历史上早达到了可观的身体尺寸。 | LI Daqing PENG Cuo YOU Hailu Matthew C. LAMANNA Jerald D. HARRIS Kenneth J. LACOVARA ZHANG Jianping | 2007 | Acta Geologica Sinica(English Edition)2007，81，4： | 4 |
| 18 | Corrosion protection of waterborne epoxy coatings containing mussel-inspired adhesive polymers based on polyaspartamide derivatives on carbon steel显示文摘A novel mussel-inspired adhesive polymer(PHEA-DOPA) containing the 3,4-dihydroxyphenylalanine(DOPA) functional group based on polyaspartamide derivatives was synthesized. The corrosion protection of the waterborne epoxy coatings containing the adhesive polymers was investigated by electrochemical impedance spectroscopy(EIS). The results indicated that the PHEA-DOPA could improve the corrosion resistance of the waterborne epoxy coating. The corrosion products were also analyzed by Raman microspectroscopy(RM), indicating the formation of the insoluble DOPA-Fe complexes on the carbon steel surface. These complexes simultaneously acting as a passivating layer, can inhibit the process of corrosion at the metal-solution interface. The differential scanning calorimeter(DSC) measurement indicated that PHEA-DOPA can increase the crosslinking density of coating. The effect of O_2 on the protective mechanism of the PHEA-DOPA coating in a 3.5% NaCl solution was also evaluated by EIS. The results indicated that the barrier effect was significantly improved under aerated conditions because DOPA was oxidized to DOPA-quinone(Dq) by O_2, which triggered the reaction with Fe ions that were released from the surface of the carbon steel. This led to more compact coatings. | Mingliang Yang Jianhua Wu Daqing Fang Bo Li Yang Yang | 2018 | Journal of Materials Science & Technology2018，34，12： | 4 |
| 19 | Inhibiting Hv1 channel in peripheral sensory neurons attenuates chronic inflammatory pain and opioid side effects显示文摘Both opioids and nonsteroidal anti-inflammatory drugs(NSAIDS)produce deleterious side effects and fail to provide sustained relief in patients with chronic inflammatory pain.Peripheral neuroinflammation(PN)is critical for initiation and development of inflammatory pain.A better understanding of molecular mechanisms underlying PN would facilitate the discovery of new analgesic targets and the development of new therapeutics.Emerging evidence suggests that peripheral sensory neurons are not only responders to painful stimuli,but are also actively engaged in inflammation and immunity,whereas the intrinsic regulatory mechanism is poorly understood.Here we report the expression of proton-selective ion channel Hv1 in peripheral sensory neurons in rodents and humans,which was previously shown as selectively expressed in microglia in mammalian central nervous system.Neuronal Hv1 was up-regulated by PN or depolarizing stimulation,which in turn aggravates inflammation and nociception.Inhibiting neuronal Hv1 genetically or by a newly discovered selective inhibitor YHV98-4 reduced intracellular alkalization and ROS production in inflammatory pain,mitigated the imbalance in downstream SHP-1-pAKT signaling,and also diminished pro-inflammatory chemokine release to alleviate nociception and morphine-induced hyperalgesia and tolerance.Thus,our data reveal neuronal Hv1 as a novel target in analgesia strategy and managing opioids-related side effects. | Qiansen Zhang Yimin Ren Yiqing Mo Peipei Guo Ping Liao Yuncheng Luo Jie Mu Zhuo Chen Yang Zhang Ya Li Linghui Yang Daqing Liao Jie Fu Juwen Shen Wei Huang Xuewen Xu Yanyan Guo Lianghe Mei Yunxia Zuo Jin Liu Huaiyu Yang Ruotian Jiang | 2022 | Cell Research2022，32，5： | 3 |
| 20 | An adaptive dwell time scheduling model for phased array radar based on three-way decision显示文摘Real-time resource allocation is crucial for phased array radar to undertake multi-task with limited resources,such as the situation of multi-target tracking,in which targets need to be prioritized so that resources can be allocated accordingly and effectively.A three-way decision-based model is proposed for adaptive scheduling of phased radar dwell time.Using the model,the threat posed by a target is measured by an evaluation function,and therefore,a target is assigned to one of the three possible decision regions,i.e.,positive region,negative region,and boundary region.A different region has a various priority in terms of resource demand,and as such,a different radar resource allocation decision is applied to each region to satisfy different tracking accuracies of multi-target.In addition,the dwell time scheduling model can be further optimized by implementing a strategy for determining a proper threshold of three-way decision making to optimize the thresholds adaptively in real-time.The advantages and the performance of the proposed model have been verified by experimental simulations with comparison to the traditional twoway decision model and the three-way decision model without threshold optimization.The experiential results demonstrate that the performance of the proposed model has a certain advantage in detecting high threat targets. | LI Bo TIAN Linyu CHEN Daqing LIANG Shiyang | 2020 | Journal of Systems Engineering and Electronics2020，31，3： | 3 |
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