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| 1 | 持续气道正压通气在预防阻塞性睡眠呼吸暂停患者心血管事件中的作用显示文摘阻塞性睡眠呼吸暂停(obstructive sleep apnea,OSA)导致阵发性低氧血症,夜间交感神经系统激活,血压、氧化应激和炎症指标的升高以及高凝血症。较大的胸内负压波动也会给心脏和大血管施加机械应力。基于人群和睡眠诊所的队列研究显示,OSA与心脑血管事件,特别是脑卒中相关。 | McEvoy RD Antic NA Heeley E Luo Y Ou Q Zhang X Mediano O Chen R Drager LF Liu Z Chen G Du B McArdle N Mukherjee S Tripathi M Billot L Li Q Lorenzi-Filho G Barbe F Redline S Wang J Arima H Neal B White DP Grunstein RR Zhong N Anderson CS 练桂丽 叶鹏 | 2016 | 中华高血压杂志2016，24，11： | 4 |
| 2 | Comparative effectiveness of i-SCAN^(TM) and high-definition white light characterizing small colonic polyps显示文摘AIM:To evaluate accuracy of in vivo diagnosis of adenomatous vs non-adenomatous polyps using i-SCAN digital chromoendoscopy compared with high-definition white light.METHODS:This is a single-center comparative effectiveness pilot study.Polyps(n = 103) from 75 averagerisk adult outpatients undergoing screening or surveillance colonoscopy between December 1,2010 and April 1,2011 were evaluated by two participating endoscopists in an academic outpatient endoscopy center.Polyps were evaluated both with high-definition white light and with i-SCAN to make an in vivo prediction of adenomatous vs non-adenomatous pathology.We determined diagnostic characteristics of i-SCAN and highdefinition white light,including sensitivity,specificity,and accuracy,with regards to identifying adenomatous vs non-adenomatous polyps.Histopathologic diagnosis was the gold standard comparison.RESULTS:One hundred and three small polyps,detected from forty-three patients,were included in the analysis.The average size of the polyps evaluated in the analysis was 3.7 mm(SD 1.3 mm,range 2 mm to 8 mm).Formal histopathology revealed that 54/103(52.4%) were adenomas,26/103(25.2%) were hyperplastic,and 23/103(22.3%) were other diagnoses include 'lymphoid aggregates','non-specific colitis,' and 'no pathologic diagnosis.' Overall,the combined accuracy of endoscopists for predicting adenomas was identical between i-SCAN(71.8%,95%CI:62.1%-80.3%) and high-definition white light(71.8%,95%CI:62.1%-80.3%).However,the accuracy of each endoscopist differed substantially,where endoscopist A demonstrated 63.0% overall accuracy(95%CI:50.9%-74.0%) as compared with endoscopist B demonstrating 93.3% overall accuracy(95%CI:77.9%-99.2%),irrespective of imaging modality.Neither endoscopist demonstrated a significant learning effect with i-SCAN during the study.Though endoscopist A increased accuracy using i-SCAN from 59%(95%CI:42.1%-74.4%) in the first half to 67.6%(95%CI:49.5%-82.6%) in the second half,and endoscopist B decreased accuracy using i-SCAN from 100%(95%CI:80.5%-100.0%) in the first half to 84.6%(95%CI:54.6%-98.1%) in the second half,neither of these differences were statistically significant.CONCLUSION:i-SCAN and high-definition white light had similar efficacy predicting polyp histology.Endoscopist training likely plays a critical role in diagnostic test characteristics and deserves further study. | Johanna L Chan Li Lin Michael Feiler Andrew I Wolf Diana M Cardona Ziad F Gellad | 2012 | World Journal of Gastroenterology2012，18，41： | 3 |
| 3 | 油炸食品与心血管病风险和全因死亡率的关系:观察性研究的荟萃分析显示文摘研究者进行了一项荟萃分析,包括剂量反应分析,以定量确定油炸食品摄入与普通成年人群心血管病风险和全因死亡率之间的关系。方法:研究者在PubMed、EMBASE和Web of Science上检索2020年4月11日之前的所有文章。应用随机效应模型估计总的相对危险度(relative risks,RR)和95%CI。结果:与最低油炸食品摄入量相比,最高摄入量者主要心血管事件的总RR(95%CI)=1.28(1.15~1.43),n=17,I^(2)=82.0%,其中前瞻性研究:1.24(1.12~1.38),n=13,I^(2)=75.7%. | 刘青(译) 练桂丽(审校) Qin P Zhang M Han M Liu D Luo X Xu L Zeng Y Chen Q Wang T Chen X Zhou Q Li Q Qie R Wu X Li Y Zhang Y Wu Y Hu D Hu F | 2021 | 中华高血压杂志2021，29，2： | 3 |
| 4 | p38α controls erythroblast enucleation and Rb signaling in stress erythropoiesis显示文摘成红血球细胞的 Enucleation 对哺乳动物在终端区别期间唯一。尽管 erythroid enucleation 广泛地被学习了,包括 retinoblastoma 蛋白质(Rb ) ,仅仅一些基因被识别了调整原子挤出。它由哪个仍然保持大部分未定义发信号的分子,外来的刺激例如 erythropoietin (Epo ) ,是 transduced 导致 enucleation。这里,我们显示出那 p38α,激活 mitogen 的蛋白质 kinase (MAPK ) ,为 erythroid enucleation 被要求。在包含高 Epo 层次并且模仿的一个前 vivo 区别系统强调红血球生成, p38α在 erythroid 区别期间被激活。p38α 的损失;完全堵住主要成红血球细胞的 enucleation。而且, p38α在胎儿、贫血的压力红血球生成期间在 vivo 以一种房间自治的方式调整成红血球细胞 enucleation。显著地, p38α 的损失;导致 p21 目标 Rb 的 p21,和减少的激活的 downregulation,哪个是成红血球细胞 enucleation 的重要管理者。这研究表明那 p38α在压力红血球生成期间是为成红血球细胞 enucleation 的一个关键发信号分子。 | Simon M Schultze Andreas Mairhofer Dan Li Jin Cen Hartmut Beug Erwin F Wagner Lijian Hui | 2012 | Cell Research2012，22，3： | 2 |
| 5 | TiAlN/Ta多层膜的力学性能及热稳定性取得新进展显示文摘TiAlN薄膜具有硬度高、附着力强及热稳定性好等优良特性,被广泛用于涂层刀具中。钽(Ta)是一种硬度高、韧性好、熔点高的过渡金属元素,经常用于提高合金的抗高温氧化性能。将Ta与TiAlN制成多层膜,有可能获得更好的力学性能及热稳定性。清华大学摩擦学国家重点实验室和武汉材料保护研究所的研究人员设计并制备了TiAlN/Ta多层膜,研究了其力学性能及热稳定性。 | Shang H F Li J Shao T M | 2014 | 中国表面工程2014，27，6： | 2 |
| 6 | Effects of Low Temperature on Dormancy Release in Lily Bulbs显示文摘 | Sun H M Jaime A T S Li Y F | 2007 | Floriculture and Ornamental Biotechnology2007，，1： | 1 |
| 7 | Electrically conductive epoxy resin composites containing polyaniline with different morphologies 显示文摘 | JIA Q M LI J B WANG L F | 2007 | Materials Science and Engineering A2007，448，： | 1 |
| 8 | Adsorption of gemini and conventional cationic Surfactants onto montmorillonite and the removal of some pollutants by the clay显示文摘 | Li F Rosen M J | 2000 | Journal of Colloid and Interface Science2000，234，2： | 1 |
| 9 | Fluorescent microsphere-based readout technology for multiplexed human single nueleotide polymorphism analysis and bacterial identification 显示文摘 | Ye F Li M S Taylor J D | 2001 | Hum Murat2001，17，4： | 1 |
| 10 | Film morphology and orientation of N-β-aminoethyl-γ-propyl polysiloxane on cellulose model substrates显示文摘 | AN Q F LI L S LI M T | 2007 | AATCC Review2007，7，5： | 1 |
| 11 | Chaotic Oscillations System Ofconstrained Pipe Conveying Fluid 显示文摘 | Paidoussis M P Li G X Moon F C | 1989 | Journal of Sound and Vibration1989，135，1： | 1 |
| 12 | The fabrication of index- modulated grating coupler in a polymeric waveguide using two- photon initiated photopolymerization显示文摘 | Dong Y Sun Y M Li Y F | 2008 | Thin Solid Films2008，516，： | 1 |
| 13 | An energy efficient clustering scheme in wireless sensor networks显示文摘 | M Ye C F Li G H Chen J Wu | 2007 | International Journal of Ad Hoc & Sensor Wireless Networks2007，3，2： | 1 |
| 14 | Research on iris image preprocessing algo- rithm显示文摘 | Zhang P F Li Q M | 2005 | IEEE Machine Learning and Cybernetics2005，8，： | 1 |
| 15 | Prediction model of secondary substances in anthocyanins synthesis of purple corn显示文摘 | ZHU M SHI Z S LI F H | 2010 | Agricultural Science&Tech-nology2010，11，15： | 1 |
| 16 | Antioxidant capacity and the relationship with polyphenol and vitamin cin actinidia fruits显示文摘 | Du GR Li M J Ma F W | 2009 | Food Chemistry2009，，113： | 1 |
| 17 | On the growth of highly ordered pores in anodized aluminumoxide显示文摘 | LI F Y ZHANG L METZGER R M | 1998 | Chem Mater1998，10，： | 1 |
| 18 | Selective hydrogenation of cinnamaldehyde to cinnamyl alcohol over an ultrafine Co-B amorphous alloy catalyst显示文摘 | LI H X CHEN X F WANG M H | 2002 | Appl Catal A General2002，225，： | 1 |
| 19 | Loss of p53 accelerates neointimal lesions of vein bypass grafts in mice显示文摘 | Mayr U Mayr M Li CH Wernig F Dietrich H Hu Y | 2002 | Circ Res2002，90，2： | 1 |
| 20 | Effects of clear plastic film mulch on yield of spring wheat显示文摘 | Li F M Guo A H Wei H | 1999 | Field Crops Research1999，63，： | 1 |
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