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| 1 | Breast milk macronutrient composition and the associated factors in urban Chinese mothers显示文摘 | Yang Titi Zhang Yumei Ning Yibing You Lili Ma Defu Zheng Yingdong Yang Xiaoguang Li Wenjun Wang Junkuan Wang Peiyu | 2014 | Chinese Medical Journal2014，，9： | 17 |
| 2 | Detection of ULF electromagnetic emissions as a precursor to two earthquakes in China显示文摘The geomagnetic data recorded by Kashi and Jinghai observatories in China were analyzed with improved polarization method.We compared the result around 0.01 Hz which is thought to be useful to detect the ULF anomaly with the result around 0.1 Hz which was inferred from the earthquake depth according to the skin effect,and found that 0.1 Hz is more proper to detect the ULF anomaly for both earthquakes studied in this paper. | Qi Li Peiyu Zhu Alimj an Mamatemin Xuegong Xu | 2011 | Earthquake Science2011，24，6： | 16 |
| 3 | A Bayesian method for comprehensive water quality evaluation of the Danjiangkou Reservoir water source area, for the middle route of the South-to-North Water Diversion Project in China显示文摘Danjiangkou 水库是为在中国的 South-to-North 水转向工程的中间的线路的水来源。因此,它的水质量地位担心大。五水质量指示物(溶解的氧,高锰酸盐索引,氨氮,全部的氮,和全部的磷),在三点被测量监视地点( Danjiangkou 水库水坝, Hejiawan 和 Jiangbei 桥),调查变化趋势,并且在到2012年5月的从2006年1月的 Danjiangkou 水库区域的水质量的空间与时间的特征。我们然后使用了一个贝叶斯的统计方法包括地评估水质量。正常分发采样方法被用来计算可能性的,并且熵重量方法被用来为对的兴趣的变量决定指示物重量到学习。结果显示所有五指示物的集中在最后六年期间增加了。另外,在水库的水质量在湿季节期间是更坏的(从 5 月到 10 月) ,比在旱季期间(从 11 月到下一年的 4 月) 。总的来说,水的概率根据为在中国的表面水的环境优秀标准,属于类型 II 的优秀范畴是 27.7%-33.7% ,比它属于另外的四种水质量类型的大。营养素的增加的集中能导致 Danjiangkou 水库的超营养作用。这个方法减少了通常与决定指示物重量和人工的分类被联系的主观,完成更可靠的结果。这些结果显示 interbasin 水转向工程在 Danjiangkou 水库区域实现综合的水质量管理是重要的[出版摘要] | Fangbing MA Chunhui LI Xuan WANG Zhifeng YANG Chengchun SUN Peiyu LIANG | 2014 | Frontiers of Earth Science2014，8，2： | 14 |
| 4 | Involvement of aquaporins in a mouse model of rotavirus diarrhea显示文摘Rotavirus diarrhea is a major worldwide cause of infantile gastroenteritis; however, the mechanism responsible for intestinal fluid loss remains unclear. Water transfer across the intestinal epithelial membrane seems to occur because of aquaporins(AQPs). Accumulating evidence indicates that alterations in AQPs may play an important role in pathogenesis. Here, we focus on changes in AQPs in a mouse model of rotavirus diarrhea. In the present study, 32 of 35 mice developed diarrhea and mild dehydration within 24 hours after infection with rotavirus strain SA11. Intestinal epithelial cells demonstrated cytoplasmic vacuolation, malaligned villi, and atrophy. AQP1 expression was significantly attenuated in the ileum and colon in comparison with controls; likewise, AQP4 and-8 protein expression were significantly decreased in the colon of rotavirus diarrhea-infected mice. In contrast, AQP3 protein expression was significantly increased in the colon of rotavirus-infected mice in comparison with controls. These results indicate that rotavirus diarrhea is associated with the downregulation of AQP1,-4, and-8 expression. Therefore, AQPs play an important role in rotavirus diarrhea. | Meiwan Cao Min Yang Zhiying Ou Dingyou Li Lanlan Geng Peiyu Chen Huan Chen Sitang Gong | 2014 | Virologica Sinica2014，29，4： | 13 |
| 5 | Microstructural variation of hardened cement-fly ash pastes leached by soft water显示文摘The microstructural variations of hardened cement-fly ash pastes leached by soft water were investigated by MIP, XRD, TG and SEM. The results show that the mass of hardened cement-fly ash paste reduces and its microstructure deteriorates partly after leaching of soft water. At the leaching duration of 180 days, the hardened paste containing fly ash deteriorated a little more serious than the plain cement paste, but the incorporation of fly ash in a proper ratio was helpful to defer the trend of deterioration of the hardened paste microstructure. The microstructural stability of hardened cement-fly ash paste wasn’t damaged severely during the 180 days leaching duration. | LI Xiang & YAN PeiYu* Department of Civil Engineering, Tsinghua University, Beijing 100084, China | 2010 | Science China(Technological Sciences)2010，53，11： | 12 |
| 6 | Prognostic Factors Predicting the Postoperative Survival Period Following Treatment for Primary Retroperitoneal Liposarcoma显示文摘 | Xudong Zhao Peiyu Li Xiaohui Huang Lin Chen Na Liu Yaoguang She | 2015 | Chinese Medical Journal2015，，1： | 9 |
| 7 | Development and validation of an endoscopic images-based deep learning model for detection with nasopharyngeal malignancies显示文摘Background:Due to the occult anatomic location of the nasopharynx and frequent presence of adenoid hyperpla-sia,the positive rate for malignancy identification during biopsy is low,thus leading to delayed or missed diagnosis for nasopharyngeal malignancies upon initial attempt.Here,we aimed to develop an artificial intelligence tool to detect nasopharyngeal malignancies under endoscopic examination based on deep learning.Methods:An endoscopic images-based nasopharyngeal malignancy detection model(eNPM-DM)consisting of a fully convolutional network based on the inception architecture was developed and fine-tuned using separate training and validation sets for both classification and segmentation.Briefly,a total of 28,966 qualified images were collected.Among these images,27,536 biopsy-proven images from 7951 individuals obtained from January 1st,2008,to December 31st,2016,were split into the training,validation and test sets at a ratio of 7:1:2 using simple randomiza-tion.Additionally,1430 images obtained from January 1st,2017,to March 31st,2017,were used as a prospective test set to compare the performance of the established model against oncologist evaluation.The dice similarity coef-ficient(DSC)was used to evaluate the efficiency of eNPM-DM in automatic segmentation of malignant area from the background of nasopharyngeal endoscopic images,by comparing automatic segmentation with manual segmenta-tion performed by the experts.Results:All images were histopathologically confirmed,and included 5713(19.7%)normal control,19,107(66.0%)nasopharyngeal carcinoma(NPC),335(1.2%)NPC and 3811(13.2%)benign diseases.The eNPM-DM attained an overall accuracy of 88.7%(95%confidence interval(CI)87.8%-89.5%)in detecting malignancies in the test set.In the prospective comparison phase,eNPM-DM outperformed the experts:the overall accuracy was 88.0%(95%CI 86.1%-89.6%)vs.80.5%(95%CI 77.0%-84.0%).The eNPM-DM required less time(40 s vs.110.0±5.8 min)and exhibited encouraging performance in automatic segmentation of nasopharyngeal malignant area from the background,with an average DSC of 0.78±0.24 and 0.75±0.26 in the test and prospective test sets,respectively.Conclusions:The eNPM-DM outperformed oncologist evaluation in diagnostic classification of nasopharyngeal mass into benign versus malignant,and realized automatic segmentation of malignant area from the background of nasopharyngeal endoscopic images. | Chaofeng Li Bingzhong Jing Liangru Ke Bin Li Weixiong Xia Caisheng He Chaonan Qian Chong Zhao Haiqiang Mai Mingyuan Chen Kajia Cao Haoyuan Mo Ling Guo Qiuyan Chen Linquan Tang Wenze Qiu Yahui Yu Hu Liang Xinjun Huang Guoying Liu Wangzhong Li Lin Wang Rui Sun Xiong Zou Shanshan Guo Peiyu Huang Donghua Luo Fang Qiu Yishan Wu Yijun Hua Kuiyuan Liu Shuhui Lv Jingjing Miao Yanqun Xiang Ying Sun Xiang Guo Xing Lv | 2018 | Cancer Communications2018，38，1： | 9 |
| 8 | Study on the hardening mechanism of cement asphalt binder显示文摘The hydration and hardening mechanism of cement asphalt binder(CAB) was studied.The early hydration process,hydration products and paste microstructure of CAB made by Portland cement and anionic asphalt emulsion were investigated by calorimetry,X-ray diffraction,and environmental scanning electron microscopy.The early hydration process of CAB can be characterized as 5 stages similar to those of Portland cement.There is no chemical reaction detected between cement and asphalt,hence no new hydration products other than those of Portland cement are produced.The hardening of CAB begins with the hydration of cement.When the hydration of cement comes into the acceleration period and its exothermic rate comes to the maximum,the coalescence of asphalt particles in asphalt emulsion is triggered.In the hardened system of CAB,it was found that the hydration products of cement form the skeleton and are covered by the continuous asphalt film.They formed an interpenetrating network system.The emulsifiers in the asphalt emulsion may retard the hydration process of cement. | YANG JinBo,YAN PeiYu,KONG XiangMing & LI Xiang Key Laboratory of Structural Engineering and Vibration of Education Ministry of China,Department of Civil Engineering,Tsinghua University,Beijing 100084,China | 2010 | Science China(Technological Sciences)2010，53，5： | 7 |
| 9 | Mineral compositions in breast milk of healthy Chinese lactating women in urban areas and its associated factors显示文摘 | Zhao Ai Ning Yibing Zhang Yumei Yang Xiaoguang Wang Junkuan Li Wenjun Wang Peiyu | 2014 | Chinese Medical Journal2014，，14： | 7 |
| 10 | Development and validation of a nomogram for predicting the survival of patients with non-metastatic nasopharyngeal carcinoma after curative treatment显示文摘Background: The TNM staging system is far from perfect in predicting the survival of individual cancer patients because only the gross anatomy is considered. The survival rates of the patients who have the same TNM stage disease vary across a wide spectrum. This study aimed to develop a nomogram that incorporates other clinicopathologic factors for predicting the overall survival(OS) of non-metastatic nasopharyngeal carcinoma(NPC) patients after curative treatments.Methods: We retrospectively collected the clinical data of 1520 NPC patients who were diagnosed histologically between November 2000 and September 2003. The clinical data of a separate cohort of 464 patients who received intensity-modulated radiation therapy(IMRT) between 2001 and 2010 were also retrieved to examine the extensibility of the model. Cox regression analysis was used to identify the prognostic factors for building the nomogram. The predictive accuracy and discriminative ability were measured using the concordance index(c-index).Results: We identiied and incorporated 12 independent clinical factors into the nomogram. The calibration curves showed that the prediction of OS was in good agreement with the actual observation in the internal validation set and IMRT cohort. The c-index of the nomogram was statistically higher than that of the 7th edition TNM staging system for predicting the survival in both the primary cohort(0.69 vs. 0.62) and the IMRT cohort(0.67 vs. 0.63).Conclusion: We developed and validated a novel nomogram that outperformed the TNM staging system in predicting the OS of non-metastatic NPC patients who underwent curative therapy. | Wenhua Liang Guanzhu Shen Yaxiong Zhang Gang Chen Xuan Wu Yang Li Anchuan Li Shiyang Kang Xi Yuan Xue Hou Peiyu Huang Yan Huang Hongyun Zhao Ying Tian Chong Zhao Li Zhang | 2016 | Chinese Journal of Cancer2016，35，12： | 6 |
| 11 | Analysis of microscopic pore structures of rocks before and after water absorption显示文摘岩石的吸水的特征被他们的显微镜的毛孔结构影响,它清楚地在水吸收以后变化。水吸收测试和扫描电子显微镜(SEM ) 在岩石上试验样品,在西藏在一个地点定位了,中国,被执行。在水吸收前后的岩石毛孔结构的变化与毛孔尺寸的分发和毛孔的分数维的特征被学习。因为新小毛孔的数字生产了,表面孔,毛孔的分数维的尺寸和毛孔结构的复杂性增加了的结果表演增加了或在岩石吸收了水以后,原来的 macropore 流动隧道被扩展。有他们的水吸收曲线上的变化的点。在另外的岩石的水吸收以后,当原来的毛孔流动隧道变得充满,表面孔和毛孔的分数维的尺寸和毛孔结构的复杂性减少了。水吸收曲线没变化。表面孔和岩石的毛孔分数维图形尺寸在水吸收前后有好线性关系。 | Li Dejian Wang Guilian Han Liqiang Liu Peiyu He Manchao Yang Guoxing Tai Qimin Chen Cheng | 2011 | Mining Science and Technology2011，21，2： | 6 |
| 12 | The Distribution and Concentration Monitoring of Benzene Industries—Six PLADs,China,2020显示文摘Summary What is already known about this topic?Benzene is classified as a Class I human carcinogen by the International Agency for Research on Cancer.Long-term exposure to benzene increases the risk of chronic benzene poisoning and leukemia.However,benzene is still widely used in the manufacturing industry.What is added by this report? | Xue Wang Jin Zhou Lei Han Xiurong Cheng Hua Shao Qiang Jia Peiyu Xu Jing Liu Jie Ren Jin Li Fei Li Baoli Zhu Meibian Zhang Caihong Xing | 2021 | China CDC weekly2021，3，43： | 4 |
| 13 | Differential expression of meat quality and intramuscular fat deposition related genes in Hanjiang black pigs显示文摘 | Guofang Wu Xin'e Shi Jiping Zhou Lei Wang Yuefeng Li Chengchuang Song Aoqi Xiang Peiyue Dong Shiduo Sun | 2014 | Acta Biochimica et Biophysica Sinica2014，46，12： | 3 |
| 14 | Study on the relationship between waste classification,combustion condition and dioxin emission from waste incineration显示文摘Domestic waste in China is mainly collected as a combination of different types of materials.The components are variable and complex,with very different combustion characteristics making it difficult to optimize the burning to reduce pollution.There are still some controversies about the accuracy of using carbon monoxide(CO)emission to characterize waste incineration performance.Here,we investigated the relationship between waste classification,incineration conditions and dioxin emission and concluded that the concentration of CO in flue gas could not be used as the only criterion of combustion efficiency and safety.Considering the close relationship between the formation of polychlorinated dibenzo-p-dioxins and dibenzofurans(PCDD/Fs)and products of incomplete combustion,the relatively low concentrations of CO are not a reliable indicator that an incinerator equipped with an activated carbon injection system and fabric filter could achieve the national standards for PCDD/F emission.The goal,therefore,is not only to lower the emission of PCDD/Fs and other pollutants through clas-sifying the waste components at the source,but also to reduce the need for the treatment of incinerated waste to protect the environment and to increase the power generation efficiency of municipal solid waste incineration(MSWI)plants.As the demand for waste disposal continues to rapidly increase,the need for a safe waste incineration system with dioxin emission controls makes the classification of waste an indispensable part of future MSWI systems. | Xiaodong Li Yunfeng Ma Mengmei Zhang Mingxiu Zhan Peiyue Wang Xiaoqing Lin Tong Chen Shengyong Lu Jianhua Yan | 2019 | Waste Disposal and Sustainable Energy2019，1，2： | 3 |
| 15 | Comprehensive profiling of EBV gene expression in nasopharyn- geal carcinoma through paired-end transcriptome sequencing显示文摘在鼻咽的癌(NPC ) 的 Epstein-Barr 病毒(EBV ) 基因的潜伏的表示模式广泛地被调查了,并且在 NPC 的几 lysin 的基因的表示被报导了。然而,通过在 NPC 的 EBV transcriptome 分析的全面信息是有限的。我们执行了对结束 RNA-seq 到系统地并且包括地在 NPC 织物和 C666-1 NPC 房间线描绘 EBV 基因的表示,它一致地带 EBV。除了限制打 II 潜伏感染,类型 III 潜伏 EBNA3s 基因和lysin 的基因的一个实质的数字的抄本,例如 BZLF1 , BRLF1 ,和 BMRF1 ,通过 RNA-seq 被检测并且进一步通过也执行的实时 PCR.We 在 C666-1 房间和 NPC 织物被验证聚类分析以 EBV 基因表示分类 NPC 耐心的组,它介绍了 NPC 样品的二种子类型。结果在 NPC 病人揭示了 EBV 基因表示的有趣的模式。这个聚类与 heterotrimeric G 蛋白质发信号有关与许多发信号的小径被相关,例如那些,发炎由 chemokine 并且 cytokine 发信号调停了,核糖体,蛋白质新陈代谢,流行性感冒感染,和 ECM 受体相互作用。我们的联合调查结果建议在 NPC 的 EBV 基因的表示被限制不仅打 II 潜伏基因而且打 III 潜伏和 lysin 的基因。这研究在 NPC 的发展提供了进一步的卓见进 EBV 的潜在的角色。 | Lijuan Hu Zhirui Lin YanhengWu Juqin Dong Bo Zhao Yanbing Cheng Peiyu Huang Lihua Xu Tianliang Xia Dan Xiong Hongbo Wang Manzhi Li Ling Guo Elliott Kieff YixinZeng | 2016 | Frontiers of Medicine2016，10，1： | 3 |
| 16 | Intelligent Industry Monitoring Network Architecture UPnP Based显示文摘 | TAN Dapeng LI Peiyu PAN Xiaohong | 2008 | Chinese Journal of Electronics2008，17，4： | 3 |
| 17 | Multi-Agent Modeling and Simulation in the AI Age显示文摘With the rapid development of artificial intelligence(AI)technology and its successful application in various fields,modeling and simulation technology,especially multi-agent modeling and simulation(MAMS),of complex systems has rapidly advanced.In this study,we first describe the concept,technical advantages,research steps,and research status of MAMS.Then we review the development status of the hybrid modeling and simulation combining multi-agent and system dynamics,the modeling and simulation of multi-agent reinforcement learning,and the modeling and simulation of large-scale multi-agent.Lastly,we introduce existing MAMS platforms and their comparative studies.This work summarizes the current research situation of MAMS,thus helping scholars understand the systematic technology development of MAMS in the AI era.It also paves the way for further research on MAMS technology. | Wenhui Fan Peiyu Chen Daiming Shi Xudong Guo Li Kou | 2021 | Tsinghua Science and Technology2021，26，5： | 2 |
| 18 | Author correction to‘Herbal formula BaWeiBaiDuSan alleviates polymicrobial sepsisinduced liver injury via increasing the gut microbiota Lactobacillus johnsonii and regulating macrophage anti-inflammatory activity in mice'[Acta Pharmaceutica Sinica B 13(2023)1164-1179]显示文摘The authors regret that there were some picture errors in Fig.7C and Supporting Information Fig.S10B owing to the negligence of the picture typesetting and careless mistakes.In Fig.7C,the H&E picture of PBS+Lipo+CLP group was the inverted picture of CLP group in Fig.5G.In Fig.7C,the H&E picture of Clo-Lipo+CLP group was zoom-in picture of L johnsoni+CLP group in Fig.8F.In Fig.SI0B,the H&E picture of ileum in CLP group was zoom-in picture of Anti-IL-10R+CLP group in Fig.S11C.The authors revise the H&E picture of liver in PBS+Lipo+CLP group and the H&E picture of liver in Clo-Lipo+CLP group in Fig.7C.Also,the H&E picture of ileum in CLP group of Fig.S10B have been revised.The correct figures are presented as below. | Xiaoqing Fan Chutian Mai Ling Zuo Jumin Huang Chun Xie Zebo Jiang Runze Li Xiaojun Yao Xingxing Fan Qibiao Wu Peiyu Yan Liang Liu Jianxin Chen Ying Xie Elaine Lai-Han Leung | 2023 | Acta Pharmaceutica Sinica B2023，13，8： | 2 |
| 19 | Aberrant functional connectivity network in subjective memory complaint individuals relates to pathological biomarkers显示文摘Background:Individuals with subjective memory complaints(SMC)feature a higher risk of cognitive decline and clinical progression of Alzheimer’s disease(AD).However,the pathological mechanism underlying SMC remains unclear.We aimed to assess the intrinsic connectivity network and its relationship with AD-related pathologies in SMC individuals.Methods:We included 44 SMC individuals and 40 normal controls who underwent both resting-state functional MRI and positron emission tomography(PET).Based on graph theory approaches,we detected local and global functional connectivity across the whole brain by using degree centrality(DC)and eigenvector centrality(EC)respectively.Additionally,we analyzed amyloid deposition and tauopathy via florbetapir-PET imaging and cerebrospinal fluid(CSF)data.The voxel-wise two-sample T-test analysis was used to examine between-group differences in the intrinsic functional network and cerebral amyloid deposition.Then,we correlated these network metrics with pathological results.Results:The SMC individuals showed higher DC in the bilateral hippocampus(HP)and left fusiform gyrus and lower DC in the inferior parietal region than controls.Across all subjects,the DC of the bilateral HP and left fusiform gyrus was positively associated with total tau and phosphorylated tau181.However,no significant between-group difference existed in EC and cerebral amyloid deposition.Conclusion:We found impaired local,but not global,intrinsic connectivity networks in SMC individuals.Given the relationships between DC value and tau level,we hypothesized that functional changes in SMC individuals might relate to pathological biomarkers. | Kaicheng Li Xiao Luo Qingze Zeng Yeerfan Jiaerken Xiaojun Xu Peiyu Huang Zhujing Shen Jingjing Xu Chao Wang Jiong Zhou Min-Ming Zhang the Alzheimer’s Disease Neuroimaging Initiative | 2018 | Translational Neurodegeneration2018，7，1： | 2 |
| 20 | Silencing of IKKε using siRNA inhibits proliferation and invasion ofglioma cells in vitro and in vivo显示文摘 | Huibing Li Lingchao Chen Anling Zhang Guangxiu Wang Lei Han Kai Yu Peiyu Pu Chunsheng Kang Qiang Huang | 2012 | International Journal of Oncology2012，，1： | 1 |
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