|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Time range of Mesozoic tectonic regime inversion in eastern North China Block显示文摘An important tectonic inversion took place in eastern North China Block(NCB) during Mesozoic, which caused a great lithosphere thinning, reconstruction of basin-range series, powerful interaction between mantle and crust, a vast granitic intrusion and volcanism, and large-scale metallogenic explosion. The time range of the Mesozoic tectonic regime inversion in the eastern North China Block is one of the key issues to understand mechanism of tectonic regime inversion. Our updated results for recognizing the time range are mainly obtained from the following aspects: structural analyses along northern and southern margins of the NCB and within the NCB for revealing tectonic inversion from compression to extension and structural striking from ~EW to NNE; geothermic analyses of the eastern sedimental basins for a great change of thermal history and regime; basin analysis for basin inversion from compression to extension and basin migration from ~EW to NNE; petrological and geochemical studies of volcanic rocks and lowermost crust xenoliths for recognizing peak period of mantle upwelling and intense interaction between mantle and crust, and main metallogenic epoch. All the studies of the above give the same time range from~150-140 Ma to ~110-100Ma, peaking at ~120 Ma. | ZHAI Mingguo ZHU Rixiang LIU Jianming MENG Qingren HOU Quanlin HU Shengbiao LIU Wei LI Zhong ZHANG Hongfu ZHANG Huafeng | 2004 | Science China Earth Sciences2004，47，2： | 89 |
| 2 | Structure and coalbed methane occurrence in tectonically deformed coals显示文摘Research on structure of tectonically deformed coals(TDC) is a key issue in coal and gas outburst prevention and coalbed methane(CBM) exploitation.This paper presents a summary on the research progress in TDC's structural-genetic classification,tectonic strain influence on coal microstructure,coal porosity system,coal chemical structure and constituents,and their relationship with the excess coalbed methane.Previous studies suggested that tectonic deformation had significant influence on coal microstructure,coal super microstructure,and even chemical macromolecular structure.The main mechanisms of coal deformation are the tectonic stress degradation and polycondensation metamorphism(dynamical metamorphism).Besides,under different deformation mechanisms,the ultra-and micro-structure and chemical constituents of TDC presented distinct characteristics.Based on these achievements,we propose one possible evolutionary trend of TDC with different deformation mechanisms,and suggest that the coal and gas outburst in the TDC,especially in the mylonitic coals,may be not only controlled by geological structure,but also influenced by the tectonic stress degradation of ductile deformation.Therefore,further study on TDC should be focused on the controlling mechanism of deformation on structure and composition of coal,generation conditions and occurrence state of excess coalbed methane from deformation mechanism of coal. | HOU QuanLin LI HuiJun FAN JunJia JU YiWen WANG TianKai LI XiaoShi WU YuDong | 2012 | Science China Earth Sciences2012，55，11： | 49 |
| 3 | Development of japonica Photo-Sensitive Genic Male Sterile Rice Lines by Editing Carbon Starved Anther Using CRISPR/Cas9显示文摘Rice is one of the most important crops as it supports over25%of total caloric intake for humans(Kusano et al.,2015).The world population reached 7.3 billion in 2015 and is projected to reach 8.5 billion in 2030(Word Population Prospects:2015 Revision).To meet the food demands for the everincreasing population with limited arable land,scarce | Quanlin Li Dabing Zhang Mingjiao Chen Wanqi Liang Jiaojun Wei Yiping Qi Zheng Yuan | 2016 | Journal of Genetics and Genomics2016，43，6： | 26 |
| 4 | Spectra response from macromolecular structure evolution of tectonically deformed coal of different deformation mechanisms显示文摘Coals with different deformation mechanisms(brittle deformation,brittle-ductile deformation,and ductile deformation) repre-sent different ways in macromolecular structure evolution based on the metamorphism.The evolution of coal structure could affect the occurrence condition of coalbed methane(CBM) because the nanopore structure affected by macromolecular struc-ture is the most important reservoir for CBM.This paper analyzes the evolutions and mechanisms of structure and functional group of tectonically deformed coals(TDCs) collected from Huainan-Huaibei coalfield using X-ray diffraction(XRD),Raman spectroscopy,and Fourier Transform Infrared(FTIR) spectroscopy methods.The results show that the macromolecular struc-ture evolutions of TDC are different from the primary structure coal as a result of the different metamorphic grade and defor-mation mechanisms.The different deformation mechanisms variously affect the process of functional group and polyconden-sation of macromolecular structure.Furthermore,the tectonic deformation leads to secondary structural defects and reduces the structure stability of TDC.The coupled evolution on stacking and extension caused by the changes of secondary structural de-fects results from different deformation mechanisms.We consider that the changes of chemical structure and secondary struc-tural defects are the primary reasons for the various structure evolutions of TDC compared with primary structure coal. | LI XiaoShi JU YiWen HOU QuanLin LIN Hong | 2012 | Science China Earth Sciences2012，55，8： | 18 |
| 5 | Renewed profile of the Mesozoic magmatism in Korean Peninsula: Regional correlation and broader implication for cratonic destruction in the North China Craton显示文摘Widespread Mesozoic magmatism occurs in the Korean Peninsula(KP). The status quo is poles apart between the northern and southern parts in characterizing its distribution and nature, with the nearly absence of any related information in North Korea. We have the opportunity to have conducted geological investigations in North Korea and South Korea during the past ten years through international cooperation programs. This led to the revelation of a number of granitoids and related volcanic rocks and thus facilitates the comparison with those in East China and Japan. Mesozoic granitoids in the KP can be divisible into three age groups: the Triassic group with a peak age of ~220 Ma, the Jurassic one of ~190–170 Ma and the late Early Cretaceous one of ~110 Ma. The Triassic intrusions include syenite, calc-alkaline to alkaline granite and minor kimberlite in the Pyeongnam Basin of North Korea. They have been considered to form in post-orogenic settings related to the Central Asian Orogenic Belt(CAOB) or the Dabie-Sulu Orogenic Belt(DSOB). The Jurassic granitoids constitute extensive occurrence in the KP and are termed as the Daebo-period magmatism. They correlate well with coeval counterparts in NE China encompassing the northeastern part of the North China Craton(NCC) and the eastern segment of the CAOB. They commonly consist of biotite or two-mica granites and granodiorites, with some containing small dark diorite enclaves. On one hand, Early Jurassic to early Middle Jurassic magmatic rocks are rare in most areas of the NCC, whilst Middle-Late Jurassic ones are not developed in the KP. On the other hand, both NCC and KP host abundant Cretaceous granites. However, the present data revealed contrasting age peaks, with ~130–125 Ma in the NCC and ~110–105 Ma in the KP. Cretaceous granites in the KP comprise the dominant biotite granites and a few amphibole granites. The former exhibit mildly fractionated REE patterns and zircon εHf(t) values from ?15 to ?25, whereas the latter feature strongly fractionated REE patterns and zircon εHf(t) values from ?10 to ?1. Both granites contain inherited zircons of ~1.8–1.9 or ~2.5 Ga. These geochemical characters testify to their derivation from re-melting distinct protoliths in ancient basement. Another Cretaceous magmatic sub-event has been entitled as the Gyeongsang volcanism, which is composed of bimodal calc-alkaline volcanic rocks of 94–55 Ma and granitic-hypabyssal granitic bodies of 72–70 Ma. Synthesizing the Mesozoic magmatic rocks across the KP, NCC and Japan can lead to the following highlights:(1) All Triassic granites in the NCC, KP and Japan have similar characteristics in petrology, chronology and geochemistry. Therefore, the NCC, KP and Japan tend to share the same tectonic setting during the Triassic, seemingly within the context of Indosinian orogensis.(2) Jurassic to earliest Cretaceous magmatic rocks in the NCC seem to define two episodes: episode A from 175 to 157 Ma and episode B from 157 to 135 Ma. Jurassic magmatic rocks in the KP span in age mainly from 190 to 170 Ma, whereas 160–135 Ma ones are rare. With the exception of ~197 Ma Funatsu granite, Jurassic magmatic rocks are absent in Japan.(3) Cretaceous granites in the KP have a peak age of ~110, ~20 Ma younger than those in the NCC, while Japan is exempt from ~130–100 Ma granites.(4) The spatial-temporal distribution and migratory characteristics of theJurassic-Cretaceous magmatic rocks in Japan, KP, and NE China-North China indicate that the subduction of the Paleo-Pacific plate might not be operative before Late Cretaceous(~130–120 Ma).(5) Late Cretaceous magmatic rocks(~90–60 Ma) occur in the southwestern corner of the KP and also in Japan, coinciding with the metamorphic age of ~90–70 Ma in the Sanbagawa metamorphic belt of Japan. The magmatic-metamorphic rock associations and their spatial distribution demonstrate the affinities of sequentially subduction zone, island arc and back-arc basin from Japan to Korea, arguing for the Pacific plate subduction during Late Cretaceous.(6) This study raises another possibility that the Mesozoic cratonic destruction in the NCC, which mainly occurred during ~150–120 Ma, might not only be due to the subduction of the Paleo-Pacific Plate, but also owe much to the intraplate geodynamic forces triggered by other adjacent continental plates like the Eurasian and Indian plates. | ZHAI MingGuo ZHANG YanBin ZHANG XiaoHui WU Fu Yuan PENG Peng LI Qiu Li HOU QuanLin LI TieSheng ZHAO Lei | 2016 | Science China(Information Sciences)2016，59，12： | 16 |
| 6 | Discovery and Significance of High CH_4 Primary Fluid Inclusions in Reservoir Volcanic Rocks of the Songliao Basin,NE China显示文摘Comparing compositions of the fluid inclusions in volcanic rocks to the contents and isotopes of the gases in corresponding volcanic reservoirs using microthermometry, Raman microspectroscopy and mass spectrum analysis, we found that: (1) up to 82 mole% methane exists in the primary inclusions hosted in the reservoir volcanic rocks; (2) high CH4 inclusions recognized in the volcanic rocks correspond to CH4-bearing CO2 reservoirs that are rich in helium and with a high 3He/4He ratio and which show reversed order of δ 13C in alkane; (3) in gas reservoirs of such abiotic methane (>80%) and a mix of CH4 and CO2, the enclosed content of CH4 in the volcanic inclusions is usually below 42 mole%, and the reversed order of δ 13C in alkane is sometimes irregular in the corresponding gas pools; (4) a glassy inclusion with a homogeneous temperature over 900°C also contains a small portion of CH4 although predominantly CO2. This affinity between gas pool and content of inclusion in the same volcanic reservoirs demonstrates that magma-originated gases, both CH4 and CO2, have contributed significantly to the corresponding gas pools and that the assumed hydrocarbon budget of the bulk earth might be much larger than conventionally supposed. | WANG Pujun HOU Qijun WANG Keyong CHEN Shumin CHENG Rihui LIU Wanzhu LI Quanlin | 2007 | Acta Geologica Sinica(English Edition)2007，81，1： | 14 |
| 7 | Response of Macromolecular Structure to Deformation in Tectonically Deformed Coal显示文摘有不同 deformational 机制和不同 deformational 紧张的构造地使变形的煤(TDC ) 的结构的进化通过 31 上的分析不同变形等级取样的 X 光检查衍射(XRD ) 深入地被调查(Ro,最大:0.7%3.1%) 从 Huaibei 煤田镇定。结果显示在有变态和变丑增加的可锻、易碎的 deformational 煤之间有不同进化特征。随变态的增加,在一方面,原子飞机间距( d002 )在步速度正在减少,叠 BSU 层( Lc )起初正在增加然后减少,但是 BSU 层( La )和 La/Lc 的比率的延期开始正在减少然后增加。为易碎的 deformational 煤,当 deformational 紧张正在增加时,在另一方面, d002 开始正在增加然后减少,它在降低中间或高中间的变态等级下面引起 Lc 和 La 的变化的倒置。在可锻的 deformational 煤,相反, d002 开始减少了然后增加,并且 Lc 的价值随 deformational 的增加减少了紧张。但是 La 的价值在降低中间的变态等级下面增加了并且起初增加了然后在高中间的变态等级下面减少了。我们断定 TDC macromolecular 结构的降级和 polycondensation 能显然在可锻的 deformational 过程期间被影响,因为统一脱臼的增加和累积也许把压力转变成紧张精力。同时,易碎的变丑能把压力转变成部分热能,并且也支持变态和降级。变丑比对可锻、易碎的 deformational 煤的微分进化的变态更重要,这能被结束。 | LI Xiaoshi JU Yiwen HOU Quanlin FAN Junjia | 2013 | Acta Geologica Sinica(English Edition)2013，87，1： | 8 |
| 8 | Spatial Pattern and Regional Types of Rural Settlements in Xuzhou City,Jiangsu Province,China显示文摘This paper principally focuses on the morphological differences,spatial pattern and regional types of rural settlements in Xuzhou City of Jiangsu Province in China.Using satellite images of Xuzhou City taken in 2007 and 2008 and models of exploratory spatial data analysis(ESDA) and spatial metrics,the paper conducts a quantitative analysis of the morphological pattern of rural settlements,and finds significant characteristics.First,rural settlements in Xuzhou City are significantly agglomerated in terms of their spatial distribution;meanwhile,there is significant variation in the geographical density distribution.Second,the scale of rural settlements in Xuzhou City is larger than the average in Jiangsu Province,and the histogram of the scale data is more even and more like a gamma distribution.There are a significant high-value cluster in the scale distribution,and local negative correlation between the scale and density distribution of rural settlements in Xuzhou City.Third,the morphology of rural settlements in Xuzhou City shows relative regularity with good connection and integrity,but the spatial variation of the morphology is anisotropic.Finally,according to the characteristics of density,scale,and form of rural settlements,the rural settlements of Xuzhou City are divided into three types:A high-density and point-scattered type,a low-density and cluster-like type and a mass-like and sparse type.The research findings could be used as the scientific foundation for rural planning and community rebuilding,particularly in less-developed areas. | MA Xiaodong QIU Fangdao LI Quanlin SHAN Yongbin CAO Yong | 2013 | Chinese Geographical Science2013，23，4： | 7 |
| 9 | Geochemical Characters of Water Coproduced with Coalbed Gas and Shallow Groundwater in Liulin Coalfield of China显示文摘To reveal the geochemical characters of water coproduced with coalbed gas and shallow groundwater,water samples were collected from 12 wells of coalbed methane and 7 wells of shallow groundwater.The pH,CODMn,fCO2,total dissolved solids(TDS),total hardness,and concentrations of metasilicic acid,sodium and kalium,calcium ion,magnesium ion,ammonium iron,bicarbonate ion,carbonate,chloride,sulfate ion,nitrate ion,fluoride,lithium,zinc,nickel,manganese,iron,boron,barium,etc.of the samples were measured.Research results showed the following:(1)Concentrations of TDS,chloride,fluoride,sodium and kalium,ammonium,iron,and barium in the water coproduced with coalbed gas exceeded the national standards of China;however,physical,chemical,and biological properties of shallow groundwater could meet the national standard.(2)The water produced from coalbed contained mainly Na–Cl·HCO3,with average TDS of 4588.5 ppm,whereas shallow groundwater contained a mixture of chemicals including Na·Mg·Ca-HCO3·SO4and Na·MgHCO3·SO4,with average TDS of 663.8 ppm.(3)In general,it was observed that bicarbonate and sodium accumulated in a reducing environment and deeper system,while depletion of hydrogen ions and dissolution of sulfate,calcium,and magnesium occurred in a redox environment and shallow system.(4)Sodium and kalium,ammonium,chloride,and bicarbonate ions were the main ions found in the study area. | YANG Mei JU Yiwen LIU Guijian TONG Li KANG Yu HOU Quanlin | 2013 | Acta Geologica Sinica(English Edition)2013，87，6： | 6 |
| 10 | The effect of different deformation mechanisms on the chemical structure of anthracite coals显示文摘To study the effect of different deformation mechanisms on the chemical structure of anthracite coals and further understand the correlation between changed chemical structures and coal and gas outburst, ten groups of sub-high-temperature and sub-high-pressure deformation experiments were performed. All samples maintained primary structure, which were collected from the Qudi Mine in the southern Qinshui Basin of China. The samples were analyzed by ultimate analysis, Vitrinite Reflection(VR), Fourier Transform Infrared spectroscopy(FTIR), and Raman spectroscopy both before and after deformation experiments for contrasting. The results showed that the VR values of all samples after experiments were significantly higher than before experiments, which suggested that the metamorphism degree of anthracite coals was increased by deformation. The results also indicated that both temperature and strain rate had significant effects on the chemical structure of anthracite coals. At a high strain rate of 4×10?5 s?1, the deformation of the samples was mainly brittle in which the mechanical energy was transformed mainly into frictional energy. In this situation, all samples developed several distinct fractured surfaces and the change of chemical structures was not obvious. On the contrary, with the decrease of the strain rates, the ductile deformation was dominated and the mechanical energy was mainly transformed into strain energy, resulting in the accumulation of deformation energy confessed by increasing quantity of dislocation and creep in the coal's interior nucleus. The absorption in the aromatic ring groups increased; otherwise the absorption in the aliphatic structures and ether oxygen groups decreased rapidly. During these experiments, CO was collected from two experimental samples. The number of aromatic rings and the structure defects within the two generated gas samples increased and the degree of molecular structure orders decreased. | XU RongTing LI HuiJun HOU QuanLin LI XiaoShi YU LiYe | 2015 | Science China Earth Sciences2015，58，4： | 4 |
| 11 | Platinum-group elements for the Kudi ophiolite, western Kunlun显示文摘The analyses of PGE characteristics for the Kudi ophiolite, western Kunlun, are reported in this note. The Ir-depleted anomalous ancient upper mantle represented by the Kudi mantle peridotites had been percolated and mixed by remelted oceanic crust material from a supra-subduction zone, leaving the rocks relatively enriched in Pd. The PGE contents in the Kudi cumulate pyroxenites and gabbros vary from 2.4 to 23.94 ng/g, and the highest values are in pyroxenites. The Pd/lr ratios increase from the pyroxenites to the gabbros. The PGE patterns for the Kudi cumulate rocks are steeply positively sloped. The Pd enrichment in these rocks is similar to that in pyroxenites from the Thetford ophiolite and the Troodos ophiolite. The Kudi diabase and basalts have low PGE contents and positively sloped PGE patterns, and are comparable with the upper pillow lava?from the Troodos ophiolite, indicative of the environment of back-arc spreading center in a supra-subduction zone. | Zhihong Wang Quanlin Hou Jiliang Li Haihong Chen | 2000 | Chinese Science Bulletin2000，45，6： | 4 |
| 12 | Moisture-induced degradation of the narrow-band red-emitting SrLiAl3N4:Eu2+phosphor显示文摘The degradation of materials plays an important role in their application and service process. In this work, the moisture-induced degradation of SrLiAl3 N4:Eu2+(SLAN), a very promising narrow-band redemitting phosphor, was comprehensively investigated by treating it in two different moisture conditions in order to reveal the potential mechanism and optimize the luminescence properties. The degradation rate gradually slows down with the decreasing environmental humidity indicating that water plays a key role in the degradation. Moreover, we take the other option with 100% humidity at different temperatures for rapid degradation. In the rapid degradation, the luminescence of SLAN is quenched quickly and the phase and micro structure change obviously, with the phosphor being bleached. The host turns into NH_3, Al_2 O_3, Sr_3 Al_2(OH)_(12) and LiAl_2(OH)_7 finally. It is further confirmed that the rapid degradation occurs with the help of water and the phosphor is oxidized during this process. | Wenxia Li Zhen Song Dianpeng Cui Zhiguo Xia Quanlin Liu | 2018 | Journal of Rare Earths2018，36，4： | 4 |
| 13 | Effects of Caragana microphylla plantations on organic carbon sequestration in total and labile soil organic carbon fractions in the Horqin Sandy Land, northern China显示文摘Afforestation is conducive to soil carbon(C) sequestration in semi-arid regions. However, little is known about the effects of afforestation on sequestrations of total and labile soil organic carbon(SOC) fractions in semi-arid sandy lands. In the present study, we examined the effects of Caragana microphylla Lam. plantations with different ages(12-and 25-year-old) on sequestrations of total SOC as well as labile SOC fractions such as light fraction organic carbon(LFOC) and microbial biomass carbon(MBC). The analyzed samples were taken from soil depths of 0–5 and 5–15 cm under two shrub-related scenarios: under shrubs and between shrubs with moving sand dunes as control sites in the Horqin Sandy Land of northern China. The results showed that the concentrations and storages of total SOC at soil depths of 0–5 and 5–15 cm were higher in 12-and 25-year-old C. microphylla plantations than in moving sand dunes(i.e., control sites), with the highest value observed under shrubs in 25-year-old C. microphylla plantations. Furthermore, the concentrations and storages of LFOC and MBC showed similar patterns with those of total SOC at the same soil depth. The 12-year-old C. microphylla plantations had higher percentages of LFOC concentration to SOC concentration and MBC concentration to SOC concentration than the 25-year-old C. microphylla plantations and moving sand dunes at both soil depths. A significant positive correlation existed among SOC, LFOC, and MBC, implying that restoring the total and labile SOC fractions is possible by afforestation with C. microphylla shrubs in the Horqin Sandy Land. At soil depth of 0–15 cm, the accumulation rate of total SOC under shrubs was higher in young C. microphylla plantations(18.53 g C/(m^2·a); 0–12 years) than in old C. microphylla plantations(16.24 g C/(m^2·a); 12–25 years), and the accumulation rates of LFOC and MBC under shrubs and between shrubs were also higher in young C. microphylla plantations than in old C. microphylla plantations. It can be concluded that the establishment of C. microphylla in the Horqin Sandy Land may be a good mitigation strategy for SOC sequestration in the surface soils. | SHANG Wen LI Yuqiang ZHAO Xueyong ZHANG Tonghui MA Quanlin TANG Jinnian FENG Jing SU Na | 2017 | Journal of Arid Land2017，9，5： | 3 |
| 14 | The large-scale ductile shear zone in Kuda, western Kunlun显示文摘A set of metamorphic suites, previously known as the Precambrian metamorphic basement in Kuda, western Kunlun has been determined as a large nappe ductile shear zone which develops penetrative foliation, oriented stretching lineation, various but consistent kinematic indicators of thrusting from north to south. The microstructure and the | Hui Zhou Jiliang Li Quanlin Hou Wenjiao Xiao Haihong Chen | 1999 | Chinese Science Bulletin1999，44，22： | 2 |
| 15 | A New Theoretical Framework of Pyramid Markov Processes for Blockchain Selfish Mining显示文摘In this paper,we provide a new theoretical framework of pyramid Markov processes to solve some open and fundamental problems of blockchain selfish mining under a rigorous mathematical setting.We first describe a more general model of blockchain selfish mining with both a two-block leading competitive criterion and a new economic incentive mechanism.Then we establish a pyramid Markov process and show that it is irreducible and positive recurrent,and its stationary probability vector is matrix-geometric with an explicitly representable rate matrix.Also,we use the stationary probability vector to study the influence of orphan blocks on the waste of computing resource.Next,we set up a pyramid Markov reward process to investigate the long-run average mining profits of the honest and dishonest mining pools,respectively.As a by-product,we build one-dimensional Markov reward processes and provide some new interesting interpretation on the Markov chain and the revenue analysis reported in the seminal work by Eyal and Sirer(2014).Note that the pyramid Markov(reward)processes can open up a new avenue in the study of blockchain selfish mining.Thus we hope that the methodology and results developed in this paper shed light on the blockchain selfish mining such that a series of promising research can be developed potentially. | Quanlin Li Yanxia Chang Xiaole Wu Guoqing Zhang | 2021 | Journal of Systems Science and Systems Engineering2021，30，6： | 2 |
| 16 | Progress and Prospects of the Strategic Priority Program on Space Science显示文摘In May 2018,the second phase of the Strategic Priority Program on Space Science(SPP II)was officially approved by the Chinese Academy of Sciences,in view of the significant scientific achievements of the first phase of the Strategic Priority Program on Space Science(SPP I)which includes 4 space science missions:the Dark Matter Particle Explorer(DAMPE),ShiJian-10(SJ-10),Quantum Experiments at Space Scale(QUESS)and Hard X-ray Modulation Telescope(HXMT).Aiming to address fundamental scientific questions,SPP II focuses on two major themes:How the universe and life originate and evolve and What is the relationship between the solar system and human beings.In areas that Chinese scientists have advantages,new space science missions including Graviational wave high-energy Electromagnetic Counterpart All-sky Monitor(GECAM),the Advanced space-based Solar Observatory(ASO-S),the Einstein Probe(EP),and Solar wind Magnetosphere Ionosphere Link Explorer(SMILE)have been approved in the framework of SPP II.This paper presents the research highlights of the SPP I,introduces the recent progress of SPP II,and puts forward the prospects for future development. | WANG Chi SUN Lilin FAN Quanlin LI Chao BAI Qingjiang | 2020 | 空间科学学报2020，40，5： | 2 |
| 17 | Mitochondrial fission factor promotes cisplatin resistance in hepatocellular carcinoma显示文摘Hepatocellular carcinoma(HCC)is the most common primary liver tumor and one of the leading causes of cancer-related death worldwide.Chemotherapeutic agents/regimens such as cisplatin(DDP)are frequently used for advanced HCC treatment.However,drug resistance remains a major hindrance and the underline mechanisms are not fully understood.In this study,we investigated the expression pattern and function of mitochondrial fission factor(Mff)in cisplatin-resistant HCC.We found that Mff is highly expressed in cisplatin-resistant HCC tissues and cell lines.Knockdown of Mff suppresses cell proliferation and promotes cell apoptosis of HCC/DDP cells.In addition,knockdown of Mff sensitizes Huh-7/DDP cells to cisplatin treatment,inhibits cell proliferation,migration and invasion,and enhances cell apoptosis.Confocal imaging showed that knockdown of Mff inhibits the mitochondrial fission and downregulates the expression of GTPase dynamin-related protein 1(Drp1)in cisplatin-resistant Huh-7/DDP cells.Moreover,xenograft tumor model revealed that knockdown of Mff sensitizes Huh-7/DDP xenograft tumor to cisplatin treatment in vivo.In summary,our findings suggest that Mff regulates mitochondrial Drp1 expression and promotes cisplatin resistance in HCC,which provides a potential therapeutic target for the treatment of cisplatin-resistant HCC. | Xiaoliang Li Quanlin Wu Fujun Ma Xinxin Zhang Lei Cai Xuekang Yang | 2022 | Acta Biochimica et Biophysica Sinica2022，54，3： | 1 |
| 18 | Evaluating the fate of p, p'-DDT in Tianjin, China using a non-steady-stale multimedia fugacity model 显示文摘 | LI Quanlin ZHU Tong QIU Xinghua | 2006 | Ecotoxicology and Environmental Safety2006，63，2： | 1 |
| 19 | Mini-Margin Nephron Sparing Surgery for Renal Cell Carcinoma 4?cm or Less显示文摘 | Quanlin Li Hongwei Guan Jie Qin Tao Jiang Maxwell V. Meng | 2010 | Advances in Urology2010，，： | 1 |
| 20 | Identification of quantitative trait loci associated with resistance to Xanthomonas oryzae pv. oryzae pathotypes prevalent in South China显示文摘Bacterial blight(BB), which is caused by Xanthomonas oryzae pv. oryzae(Xoo), is an important rice disease responsible for significant yield losses. In the rice-growing regions of South China where BB outbreaks are common, the resistance of cultivars with BB resistance genes Xa4 and Xa21 has been lost because of rapid changes in the Xoo population structure and virulence. In this study, 421 diverse rice accessions were evaluated regarding their resistance to two Xoo strains, namely GD1358(C5) and IV, which are prevalent pathotypes in South China and overcame the resistance of Xa4 and Xa21, respectively. Using the 4.8 mio filtered SNP dataset, we conducted a genome-wide association study, which identified 13 loci associated with BB resistance, including eight new quantitative trait loci(QTL) and five QTL harboring known BB resistance genes: Xa3/Xa26, xa5, Xa35(t), Xa36(t), Xa40, Xa43(t), and xa44(t). Intriguingly, a steep peak was detected on chromosomes 5 and 11. Six QTL including three new ones, were distributed on chromosome 11, whereas a new QTL q BB5.1 and a known QTL were detected on chromosome 5. Haplotype analyses indicated that the LOC;s05 g01610(Os PRAF2) gene within the q BB5.1 region, which encodes a PRAF protein, is associated with BB resistance. Furthermore, Os PRAF2 knockout lines generated using the CRISPR-Cpf1 system were significantly more resistant to Xoo strains than the wild-type plants. Our results provide researchers and breeders with useful information regarding QTL and gene resources,which may be relevant for developing new BB-resistant rice cultivars. | Jialing Lu Quanlin Li Chunchao Wang Mingming Wang Dan Zeng Fan Zhang Wenxue Zhai Yongli Zhou | 2022 | The Crop Journal2022，10，2： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员