|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Cotton GhPOX1 encoding plant class Ⅲ peroxidase may be responsible for the high level of reactive oxygen species production that is related to cotton fiber elongation显示文摘The accumulation of reactive oxygen species(ROS) is involved in plant cell development.In plant,class Ⅲ peroxidases are heme-containing enzymes encoded by a large multi-gene family participated in the release or consumption of ROS.The specific function of each member of the family is still elusive.Here,we showed that ROS was significantly generated during cotton fiber initiation and elongation,whereas,application of NADPH oxidase inhibitor diphenyleneiodonium(DPI) and peroxidase inhibitor salicylhydroxamic acid(SHAM) to the wild-type cotton ovule culture significantly suppressed fiber growth,respectively.Their inhibitory effects were caused by the reduction of superoxide radical(O2-).Ten GhPOX genes(cDNAs) encoding cotton class Ⅲ peroxidases were isolated,among them eight GhPOX genes were reported for the first time.Microarray analyses indicated that GhPOX1 was the mostly predomi-nantly expressed in fast-elongating cotton fiber cells.Real-time quantitative PCR analysis revealed the transcript level of GhPOX1 was over 400-fold higher in growing fiber cells than in ovules,flowers,roots,stems and leaves.To reveal the role of GhPOX1 in plant devel-opment,its Arabidopsis orthologue atpox13 mutant was demonstrated to be defective in branch root development.Taken together,the data suggest that GhPOX1 plays an important role during fiber cell elongation possibly by mediating production of reactive oxygen spe-cies. | Wenqian Mei Yongmei Qin Wenqiang Song Jun Li Yuxian Zhu | 2009 | Journal of Genetics and Genomics2009，36，3： | 19 |
| 2 | SHRIMP zircon U-Pb dating for gabbro from the Tiding ophiolite in Tibet显示文摘 | WANG Ran XIA Bin ZHOU Guoqing ZHANG Yuquan YANG Zhiqing LI Wenqian WEI Dongliang ZHONG Lifeng XU Lifeng | 2006 | Chinese Science Bulletin2006，51，14： | 14 |
| 3 | Challenges of evaluating immunotherapy efficacy in solid tumors显示文摘Immunotherapy is one of the most promising treatments for multiple tumor types.The significant clinical benefits and durable responses of immunotherapy have led to the emergence of various immune-related clinical response patterns that extend beyond those achieved with cytotoxic agents.Various studies investigated the efficacy of immunotherapy,including the effect on tumor size,long-term survival benefits,and the ability to overcome the particularly challenging survival curves tailing phenomenon.The current immune-related methods guidelines,such as immune-related Response Criteria(irRC),immune-related Response Evaluation Criteria in Solid Tumors(irRECIST),immune Response Evaluation Criteria in Solid Tumors(iRECIST),and immune-modified Response Evaluation Criteria in Solid Tumors(imRECIST),could be well-adapted to identify the heterogeneity of responses that appear in patients receiving immunotherapy,such as pseudoprogression(PsPD)and hyperprogressive disease(HPD),and to some extent to overcome the limitation of evaluating the efficacy of immunotherapy on tumor size by imaging.Additionally,a second type of evaluation method was proposed based on survival,which includes milestone analysis and restricted mean survival time.Currently,milestone analysis is a complementary tool to summarize and interpret trial results along with more conventional measures of survival and other less established metrics.A golden standard evaluation method to distinguish the efficacy of immunotherapy may improve the process of imaging and aid survival-based efficacy evaluation in patients with solid tumors. | Rilan Bai Wenqian Li Nawen Du Jiuwei Cui | 2019 | Chinese Journal of Cancer Research2019，31，6： | 8 |
| 4 | Soil phosphorus availability and rice phosphorus uptake in paddy fields under various agronomic practices显示文摘Agronomic practices affect soil phosphorus(P) availability, P uptake by plants, and subsequently the efficiency of P use. A field experiment was carried out to investigate the effects of various agronomic practices(straw incorporation, paddy water management, nitrogen(N) fertilizer dose, manure application,and biochar addition) on soil P availability(e.g., soil total P(STP), soil available P(SAP), soil microbial biomass P(SMBP), and rice P uptake as well as P use efficiency(PUE)) over four cropping seasons in a rice-rice cropping system, in subtropical central China. Compared to the non-straw treatment(control,using full dose of chemical N fertilizer), straw incorporation increased SAP and SMBP by 9.3%–18.5% and 15.5%–35.4%, respectively;substituting half the chemical N fertilizer dose with pig manure and the biochar application increased STP, SAP, and SMBP by 10.5%–48.3%, 30.2%–236.0%, and 19.8%–72.4%,respectively, mainly owing to increased soil P and organic carbon inputs;adding a half dose of N and no N input(reduced N treatments) increased STP and SAP by 2.6%–7.5% and 19.8%–33.7%, respectively, due to decreased soil P outputs. Thus, soil P availability was greatly affected by soil P input and use. The continuous flooding water regime without straw addition significantly decreased SMBP by 11.4% compared to corresponding treatments under a mid-season drainage water regime. Total P uptake by rice grains and straws at the harvest stage increased under straw incorporation and under pig manure application, but decreased under the reduced N treatments and under biochar application at a rate of 48 t ha-1, compared to the control. Rice P uptake was significantly positively correlated with rice biomass, and both were positively correlated with N fertilizer application rates, SAP, SMBP, and STP. Phosphorus use efficiency generally increased under straw incorporation but decreased under the reduced N treatments and under the manure application(with excessive P input), compared to the control. These results showed that straw incorporation can be used to increase soil P availability and PUE while decreasing the use of chemical P fertilizers. When substituting chemical fertilizers with pig manure, excess P inputs should be avoided in order to reduce P accumulation in the soil as well as the environmental risks from non-point source pollution. | Bingshen JIANG Jianlin SHEN Minghong SUN Yajun HU Wenqian JIANG Juan WANG Yong LI Jinshui WU | 2021 | Pedosphere2021，31，1： | 6 |
| 5 | Three-Dimensional Tidal Model and Its Application to Numerical Simulation of Water Quality in Coastal Waters显示文摘- The turbulence mechanism plays an important part in the mixing process and momentum transfer of turbulence. A three-dimensional Prandtl mixing length tidal model has been developed to simulate tidal flows and water quality. The eddy viscosities and diffusivities are computed from the Prandtl mixing length model. In order to model the water quality of an estuary or coastal area many interdependent processes need to be simulated. These may be conveniently separated into three main groups: transport and mixing processes, biochemical interaction of water quality variables and the utilization and re-cycling of nutrients by living matter. The model simulates full oxygen and nutrient balance, primary productivity and the transport, reaction mechanism and fate of pollutants over tidal time-scales. The model is applied to numerical simulation of tidal flows and water quality in Dalian Bay. The model has been calibrated against a limited data set of historical water quality observations and in general | Shen Yongming , Li Yucheng and Zhao Wenqian Associate Professor, Department of Civil Engineering, Dalian University of Technology, Dalian 116023 Professor, Department of Civil Engineering, Dalian University of Technology, Dalian 116023 Professor, Department of Civil Engineering, Sichuan Union University, Chengdu 610065 | 1994 | China Ocean Engineering1994，9，4： | 5 |
| 6 | Clinical challenges in neoadjuvant immunotherapy for non-small cell lung cancer显示文摘Immune checkpoint inhibitors(ICIs),a type of immunotherapy,have become one of the most important therapeutic options for first-and second-line treatment of advanced non-small cell lung cancer(NSCLC).Recent clinical studies have shown that immunotherapy can offer substantial survival benefits to patients with early-stage or resectable advanced NSCLC.However,considering the importance of timing when using ICIs and their associated adverse events(AEs),the advantages and disadvantages of using these agents need to be weighed carefully when deciding the use of a combined treatment.In addition,the inconsistency between imaging assessment and pathological results poses further challenges to the evaluation of efficacy of neoadjuvant immunotherapy.It is also important to develop new methodologies and discover suitable biomarkers that can be used to evaluate survival outcomes of immunotherapy and identify patients who would benefit the most from this treatment.In this review,we aimed to summarize previous results of ongoing clinical trials on neoadjuvant immunotherapy for lung cancer and discuss the challenges and future perspectives of this therapeutic approach in the treatment of resectable NSCLC. | Hanfei Guo Wenqian Li Lei Qian Jiuwei Cui | 2021 | Chinese Journal of Cancer Research2021，33，2： | 5 |
| 7 | The Kinetics for Electrochemical Removal of Ammonia in Coking Wastewater显示文摘Electrochemical removal of ammonia is a new and effective method in coking wastewater.The reaction mechanism of ammonia removal was proved by stable polarization curve in this paper.First,the supposing of reaction steps of the electrode were proposed.And then reaction parameter of the electrode was measured by Tafel curve.Finally,the reaction mechanism was determined by quasi-equilibrium approach.The results showed that Cl2+H2O→HOCl+H++Cl was the rate-determining step,the calculated apparent transfer coefficient was uniform to the experimental value. | LIANG Zhenhai LI Su GUO Wenqian FAN Caimei | 2011 | Chinese Journal of Chemical Engineering2011，19，4： | 5 |
| 8 | Effective control allocation using hierarchical multi-objective optimization for multi-phase flight显示文摘For different flight phases in an overall flight mission,different control and allocation preferences should be pursued considering lift,drag or maneuverability characteristics.The multi-objective flight control allocation problem for a multi-phase flight mission is studied.For an overall flight mission,different flight phases namely climbing,cruise,maneuver and gliding phases are defined.Firstly,a multi-objective control allocation problem considering drag,lift or control energy preference is constructed.Secondly,considering different control preferences at different flight phases,the analytic hierarchical process method is used to construct a comprehensive performance index from different objectives such as lift or drag preferences.The active set based dynamic programming optimization method is used to solve the real-time optimization problem.For the validation,the Innovative Control Effector(ICE)tailless aircraft nonlinear model and the angular acceleration measurements based adaptive Incremental Backstepping(IBKS)are used to construct the validation platform.Finally,an overall flight mission is simulated to demonstrate the efficiency of the proposed multi-phase and multi-objective flight control allocation method.The results show that the comprehensive performance index for different phases,which are determined from the Analytic Hierarchy Process(AHP)method,can suitably satisfy the preference requirements for different flight phases. | Liguo SUN Qing ZHOU Baoxu JIA Wenqian TAN Hangxu LI | 2020 | Chinese Journal of Aeronautics2020，33，7： | 4 |
| 9 | Exogenous abscisic acid coordinating leaf senescence and transport of assimilates into wheat grains under drought stress by regulating hormones homeostasis显示文摘Drought at the grain filling stage of wheat will cause premature leaf senescence, thus leading to considerable loss of wheat yield. Therefore, this paper aims to establish a cultivation technology for strong drought resistance, delayed senescence, and yield improvement based on the analysis of hormones homeostasis obtained by applying chemical control substances. Experiments were conducted with two genotypes of wheat. Four water irrigation treatments were applied to impose the water deficit, including well-watered control treatment(WW), mild water deficit(MiWD), moderate water deficit(MoWD), and severe water deficit(SWD). Exogenous abscisic acid(ABA) was sprayed on the plants at the anthesis stage of the wheat. As a result, exogenous ABA reduced initial senescence rate(r0), total duration of chlorophyll(Chltotal), rapid senescence phase(Chlloss), and the accumulated temperature at an inflection point(M) but improved the persistence phase(Chlper) of flag leaves under all of the four treatments. However, exogenous ABA produced inconsistent effects on photoassimilate relocation and grain weight under different treatments. It produced positive regulatory effects on grain weight under WW, MiWD, and MoWD treatments. On the one hand, spraying ABA during the persistence phase of flag leaves reduced the ratios of zeatin to gibberellin(Z/GA3), spermine to spermidine(Spm/Spd), and salicylic acid to ABA(SA/ABA),which prolonged active photosynthesis by stimulating high level of proline(Pro) and increased the activities of antioxidant enzymes, such as superoxide dismutase(SOD), peroxidase(POD), catalase(CAT), and ascorbate peroxidase(APX). Therefore, drought tolerance was enhanced, and more photosynthetic assimilates were accumulated. On the other hand, the rapid senescence phase and the transport rate of assimilates into grains were accelerated, resulting in higher grain weight, yield, and water use efficiency(WUE). However, under SWD treatment, exogenous ABA improved the ratio of SA/ABA, leading to low Pro content and low antioxidant enzyme activity of flag leaves in the rapid loss phase. Meanwhile,drought resistance declined and the transport duration of assimilates into grains was shortened, thus making photosynthetic assimilates redundant. Therefore, exogenous ABA can lead to the reduction in grain weight, yield, and WUE of wheat under SWD treatment. | Yongli Luo Wenqian Li Cui Huang Junhao Yang Min Jin Jin Chen Dangwei Pang Yonglan Chang Yong Li Zhenlin Wang | 2021 | The Crop Journal2021，9，4： | 4 |
| 10 | Sin1/mTORC2 regulate B cell growth and metabolism by activating mTORC1 and Myc显示文摘Proper control of B cell growth and metabolism is crucial for B-cell-mediated immunity,but the underlying molecular mechanisms remain incompletely understood.In this study,Sin1,a key component of mTOR complex 2(mTORC2),specifically regulates B cell growth and metabolism.Genetic ablation of Sin1 in B cells reduces the cell size at either the transitional stage or upon antigen stimulation and severely impairs metabolism.Sin1 deficiency also severely impairs B-cell proliferation,antibody responses,and anti-viral immunity.At the molecular level,Sin1 controls the expression and stability of the c-Myc protein and maintains the activity of mTORC1 through the Akt-dependent inactivation of GSK3 and TSC1/2,respectively.Therefore,our study reveals a novel and specific role for Sin1 in coordinating the activation of mTORC2 and mTORC1 to control B cell growth and metabolism. | Man Li Adam S.Lazorchak Xinxing Ouyang Huihui Zhang Hongzhi Liu Omotooke A.Arojo Lichong Yan Jingsi Jin Yuheng Han Guojun Qu Yuhong Fu Xiaocao Xu Xiaobo Liu Wenqian Zhang Zhengfeng Yang Chuan Ruan Qijun Wang Dou Liu Chuanxin Huang Lu Lu Shibo Jiang Fubin Li Bing Su | 2019 | Cellular & Molecular Immunology2019，16，9： | 4 |
| 11 | Paleoseismologic record of earthquakes along the Wuzunxiaoer section of the Altyn Tagh fault and its implication for cascade rupture behavior显示文摘The Altyn Tagh fault is one of the few great active strike-slip faults in the world. The recurrence characteristics of paleoearthquakes on this fault are still poorly understood due to the lack of paleoseismic records recorded in high-resolution strata. We document a paleoseismic record in a pull-apart basin along the Wuzunxiaoer section of the central Altyn Tagh fault.The high-resolution strata recorded abundant seismic deformations and their sedimentary responses. Four earthquakes are identified based on event evidence in the form of open fissures, thickened strata, angular unconformities, and folds. The occurrence times of the four events were constrained using radiocarbon dating. Event W1 occurred at AD1220–1773, events W2 and W3 occurred between 407 and 215 BC, and event W4 occurred slightly earlier at 1608–1462 BC, indicating clustered recurrence characteristics. A comparison of the earthquake records along the Wuzunxiaoer section with other records along the Xorkoli section suggests that both sections ruptured during the most recent event. | Zhaode YUAN Jing LIU-ZENG You ZHOU Zhigang LI Heng WANG Wenqian YAO Longfei HAN | 2020 | Science China Earth Sciences2020，63，1： | 3 |
| 12 | Research progress on properties of pre-gelatinized starch and its application in wheat flour products显示文摘Starch is the most abundant organic compound in nature,second only to cellulose.However,the conserved structure of native starches limits their properties and applications.Therefore,it is often necessary to modify them to obtain specific properties.As a common green and safe physical modification method,pre-gelatinization can improve the cold water solubility and swelling power of starch.The typical preparation methods of pre-gelatinized starch include spray drying,extrusion,and drum drying.Spray-dried pre-gelatinized starch still had good granule shape,but the increase of cold water solubility and cold paste viscosity was relatively small.Extruded and drum-dried pre-gelatinized starch showed serious structure destruction,significant increases in cold water solubility and cold paste viscosity,but relatively low hot paste viscosity.The properties of pre-gelatinized starch obtained by different methods are different,so do their effects on the quality of flour products.Wheat flour products,as one of the leading staple food for the people all over the world,play a vital role in people's daily life.With the improvement of people's living standards,more and more special flour products with unique features have received attentions of consumers and researchers.However,the sensory characteristics of special flour products are often inferior to traditional flour products,which limits its development.The unique functional characteristics of pre-gelatinized starch make it expected to play an essential role in the quality improvement of featured flour products.In this paper,the granule morphology,crystal structure,hydration and gelatinization properties of pre-gelatinized starch prepared by three common methods and their application in flour products were reviewed,which provides a theoretical basis for the application of pre-gelatinized starch in food industry. | Hao Ma Mei Liu Ying Liang Xueling Zheng Le Sun Wenqian Dang Jie Li Limin Li Chong Liu | 2022 | Grain & Oil Science and Technology2022，5，2： | 3 |
| 13 | Detailed mapping of the surface rupture of the 12 February 2014 Yutian M_s7.3 earthquake,Altyn Tagh fault,Xinjiang,China显示文摘Large-scale detailed mapping plays a key role in revealing the rupture characteristics and mechanisms of strong earthquakes.Relatively few studies have been performed on the surface ruptures of large earthquakes in central and western Tibet due to its remote nature and high elevation.Based on high-resolution unmanned aerial vehicle(UAV)photography,we mapped the coseismic surface rupture of the 2014 Yutian M_s7.3 earthquake.Along the western Altyn Tagh fault system,the earthquake produced~37 km of surface rupture along the South Xor Kol fault(southern section S1),Xor Kol fault(central section S2)and Ashikule fault(northern section S3).Section S1 has a 16-km-long surface rupture with an average sinistral offset of 52±25 cm and a maximum offset of~90 cm,while section S3 has a 14.2-km-long surface rupture with an average sinistral offset of 36±21 cm and a maximum offset of~84 cm.A compilation of 5308 cracks yields an average crack width along the southern section of 85±71 cm and a maximum width of~700 cm;the average width along the central section is 39±21 cm,and the maximum width is 243 cm;and the average width along the northern section is 61±44 cm with a maximum of~340 cm.In addition,the average cumulative opening across rupture zone is 3.4±2.9 m along the southern section,with a maximum of~17 m;4.3±3.6 m along the central section,with a maximum of~13 m;and 1.7±1.6 m along the northern section,with a maximum of~6 m.Evidently,the average crack width and cumulative opening decrease towards bends and steps along the fault.A global synthesis of surface rupture distributions corresponding to strike-slip earthquakes indicates that the rupture zone is wider near the complex parts of fault geometries(such as bends,steps and fault bifurcations)than along straight sections,suggesting that the fault geometry has an obvious control on the surface rupture width.The widespread cracks at the intersection between the Xor Kol and South Xor Kol faults may indicate that an extensional regime is more likely to produce distributed offfault deformation,which provides an observational constraint for the numerical simulation of dynamic rupture on a fault.In addition to coseismic surface rupture,the Yutian earthquake also produced a large number of gravity-driven slides on alluvial fans with gentle slopes.The friction efficiency of the water-bearing salt layer beneath fans could decrease the sliding threshold and trigger instability under surface shaking.These distributed deformations and gravity-driven slides reflect the coupling between the rupture propagation and fault geometry and indicate that the rupture may have propagated in two directions along the Ashikule fault after passing through a step.Therefore,the investigation of coseismic surface rupture provides important observational constraints on the dynamic rupture process. | Zhaode YUAN Jing LIU-ZENG Xue LI Jing XU Wenqian YAO Longfei HAN Tao LI | 2021 | Science China Earth Sciences2021，64，1： | 3 |
| 14 | Recovery of bismuth and antimony metals from pressure-leaching slag显示文摘The leaching behavior of metals from a pressure-leaching slag was investigated using a desulphurization-leaching-hydrolysis process for the recovery of bismuth and antimony.Various parameters were studied,including the amount of acid added,temperature,time,addition of NaCl and solid-liquid ratio in the leaching process.The experimental results show that the contents of bismuth and antimony are mostly enriched in the process of kerosene desulphurization.More than 98% Sb and 96% Bi are extracted under the determined conditions.In the process of hydrolysis,the precipitation rates of bismuth and antimony are 97.80% and 94.59%,respectively.Under the optimum experimental conditions,the recovery rate of bismuth and antimony can be up to 95.80% and 90.80%,respectively. | Zhang, Bao Li, Qian Shen, Wenqian Min, Xiaobo | 2012 | Rare Metals2012，31，1： | 3 |
| 15 | Simultaneous determination of bisphenols, benzophenones and parabens in human urine by using UHPLC-TQMS显示文摘Bisphenols, benzophenones and parabens may alter one or more functions of endocrine system and consequently cause adverse health effects on human. A rapid and sensitive analytical method for the simultaneous determination of six bisphenols, five benzophenones and seven parabens in human urine by using ultra-high performance liquid chromatography coupled with triple quadrupole mass spectrometry was developed and applied for human urine sample analysis. The eighteen targeted compounds were separated within 11 min. Heated-electrospray ionization was operated with multiple reaction monitoring in negative-ion mode. The limit of detection ranged from 0.01 ng/mL to 0.5 ng/mL.Seven isotope-labeled internal standards were used in the quantitative analysis. After the method was validated for sensitivity, linearity, precision, accuracy and matrix effect, it was applied for the analysis of human urine samples to evaluate the profiles of human exposure. Eight of the targeted analytes were detected in more than 50% urine samples. | Hongzhi Zhao Jiufeng Li Xinli Ma Wenqian Huo Shunqing Xu Zongwei Cai | 2018 | Chinese Chemical Letters2018，29，1： | 3 |
| 16 | High-resolution structure-from-motion models covering 160 km-long surface ruptures of the 2021 M_(W)7.4 Madoi earthquake in northern Qinghai-Tibetan Plateau显示文摘The May 222021 M_(W)7.4 Madoi,Qinghai,China earthquake presented a rare opportunity to apply the modern unmanned aerial vehicle(UAV)photography method in extreme altitude and weather conditions to image surface ruptures and near-field effects of earthquake-related surface deformations in the remote Tibet.High-resolution aerial photographs were acquired in the days immediately following the mainshock.The complex surface rupture patterns associated with this event were covered comprehensively at 3-6 cm resolution.This effort represents the first time that an earthquake rupture in the interior of the Qinghai-Tibetan Plateau has been fully and systematically captured by such high-resolution imagery,with an unprecedented level of detail,over its entire length.The dataset has proven valuable in documenting subtle and transient rupture features,such as the significant mole-tracks and opening fissures,which were ubiquitous coseismically but degraded during the subsequent summer storm season.Such high-quality imagery also helps to document with high fidelity the fractures of the surface rupture zone(supplements of this paper),the pattern related to how the faults ruptured to the ground surface,and the distribution of off-fault damage.In combination with other ground-based mapping efforts,the data will be analyzed in the following months to better understand the mechanics of earthquake rupture related to the fault zone rheology,rupture dynamics,and frictional properties along with the fault interface. | Jing Liu-Zeng Wenqian Yao Xiaoli Liu Yanxiu Shao Wenxin Wang Longfei Han Yan Wang Xianyang Zeng Jinyang Li Zijun Wang Zhijun Liu Hongwei Tu | 2022 | Earthquake Research Advances2022，2，2： | 3 |
| 17 | Interactions between cytokinin and nitrogen contribute to grain mass in wheat cultivars by regulating the flag leaf senescence process显示文摘Premature senescence after anthesis reduces crop yields.Delaying leaf senescence could maintain photosynthetic activity for a longer period and lead to a higher photosynthetic rate.Recent studies have provided some insights into the interaction between cytokinin and nitrogen(N)in the regulation of plant development.In the present study,foliar application of exogenous 6-benzylaminopurine(6-BA)and lovastatin,an inhibitor of cytokinin synthesis,was combined with three N rates[0 kg ha^(-1)(low nitrogen,LN),240 kg ha^(-1)(normal nitrogen,NN),and 360 kg ha^(-1)(high nitrogen,HN)]in two wheat cultivars,Wennong 6(with a staygreen phenotype)and Jimai 20(with a non-staygreen phenotype).Flag leaf senescence was assessed using a Gompertz growth curve.Grain mass,dry matter accumulation and distribution,total N of flag leaf,and concentrations of zeatin riboside(ZR)and abscisic acid(ABA)were also used to evaluate the functional characteristics of flag leaves.Grain mass was negatively correlated with initial senescence rate(r_0)and duration of rapid chlorophyll loss(Chl_(loss)),whereas it was positively correlated with maximum senescence rate(r_(max)),average senescence rate(r_(aver)),persistence phase(Chl_(per)),total duration of flag leaf(Chl_(total))and inflection point cumulative temperature(M).Compared to Jimai 20,Wennong 6 had larger r_(aver),Chl_(per),and Chl_(total).The concentration of ZR was highest under the 6-BA×NN treatment,followed by the 6-BA×HN and 6-BA×LN treatments.However,the concentration of ABA showed the opposite trend.It was concluded that the staygreen phenotype Wennong 6 was associated with greater grain mass and altered cytokinin metabolism and could be classified as a functional staygreen type.Foliar application of 6-BA interacting with N at the NN level(240 kg ha^(-1))may be a beneficial strategy for improving grain yield of wheat by regulating endogenous hormones and the flag leaf senescence process.Increasing endogenous cytokinin promoted the transport of dry matter to grain. | Yongli Luo Yuhai Tang Xin Zhang Wenqian Li Yonglan Chang Dangwei Pang Xu Xu Yong Li Zhenlin Wang | 2018 | The Crop Journal2018，6，5： | 2 |
| 18 | Genome-wide analysis of expression quantitative trait loci(eQTLs)reveals the regulatory architecture of gene expression variation in the storage roots of sweet potato显示文摘Dissecting the genetic regulation of gene expression is critical for understanding phenotypic variation and species evolution.However,our understanding of the transcriptional variability in sweet potato remains limited.Here,we analyzed two publicly available datasets to explore the landscape of transcriptomic variations and its genetic basis in the storage roots of sweet potato.The comprehensive analysis identified a total of 724,438 high-confidence single nucleotide polymorphisms(SNPs)and 26,026 expressed genes.Expression quantitative trait locus(eQTL)analysis revealed 4408 eQTLs regulating the expression of 3646 genes,including 2261 local eQTLs and 2147 distant eQTLs.Two distant eQTL hotspots were found with target genes significantly enriched in specific functional classifications.By combining the information from regulatory network analyses,eQTLs and association mapping,we found that IbMYB1-2 acts as a master regulator and is the major gene responsible for the activation of anthocyanin biosynthesis in the storage roots of sweet potato.Our study provides the first insight into the genetic architecture of genome-wide expression variation in sweet potato and can be used to investigate the potential effects of genetic variants on key agronomic traits in sweet potato. | Lei Zhang Yicheng Yu Tianye Shi Meng Kou Jian Sun Tao Xu Qiang Li Shaoyuan Wu Qinghe Cao Wenqian Hou Zongyun Li | 2020 | Horticulture Research2020，7，1： | 2 |
| 19 | Atmospheric oxidizing capacity in autumn Beijing:Analysis of the O_(3) and PM_(2.5) episodes based on observation-based model显示文摘Atmospheric oxidizing capacity(AOC)is the fundamental driving factors of chemistry process(e.g.,the formation of ozone(O_(3))and secondary organic aerosols(SOA))in the troposphere.However,accurate quantification of AOC still remains uncertainty.In this study,a comprehensive field campaign was conducted during autumn 2019 in downtown of Beijing,where O_(3) and PM_(2.5) episodes had been experienced successively.The observation-based model(OBM)is used to quantify the AOC at O_(3) and PM_(2.5) episodes.The strong intensity of AOC is found at O_(3) and PM2.5 episodes,and hydroxyl radical(OH)is the dominating daytime oxidant for both episodes.The photolysis of O_(3) is main source of OH at O_(3) episode;the photolysis of nitrous acid(HONO)and formaldehyde(HCHO)plays important role in OH formation at PM_(2.5) episode.The radicals loss routines vary according to precursor pollutants,resulting in different types of air pollution.O_(3) budgets and sensitivity analysis indicates that O_(3) production is transition regime(both VOC and NOx-limited)at O3 episode.The heterogeneous reaction of hydroperoxy radicals(HO_(2))on aerosol surfaces has significant influence on OH and O_(3) production rates.The HO_(2) uptake coefficient(γHO_(2))is the determining factor and required accurate measurement in real atmospheric environment.Our findings could provide the important bases for coordinated control of PM_(2.5) and O_(3) pollution. | Chenhui Jia Shengrui Tong Xinran Zhang Fangjie Li Wenqian Zhang Weiran Li ZhenWang Gen Zhang Guiqian Tang Zirui Liu Maofa Ge | 2023 | Journal of Environmental Sciences2023，，2： | 2 |
| 20 | Hormones induce the formation of luminal-derived basal cells in the mammary gland显示文摘In the mammary gland, it is widely believed that the luminal cells are unipotent after birth, contributing only to the luminal compartment in normal development. Here, by lineage tracing, we uncovered an unexpected potential of luminal cells that can give rise to basal cells during pregnancy. These luminal-derived basal cells (LdBCs) persisted through mammary regression and gen erated more proge ny in successive rounds of preg nan cies. LdBCs express basal markers as well as estroge n receptor a (ERa). I n ovariectomized (OVX) mice, stimulation with estrogen and progesterone promoted the formation of LdBCs. In serial transplantation assays, LdBCs were able to rec on stitute new mammary glands in a hormone-depende nt manner. Tran scriptome an alysis and genetic experiments suggest that Wnt/p-catenin signaling is essential for the formation and maintenance of LdBCs. Our data uncover an unexpected bi-potency of luminal cells in a physiological context. The discovery of ERa+ basal cells, which can respond to hormones and are endowed with stem cell-like regenerative capacity in parous mammary gland, provides new insights into the association of hormones and breast cancer. | Wenqian Song Ran Wang Weimin Jiang Qi Yin Guangdun Peng Ruikai Yang Qing Cissy Yu Jianfeng Chen Jingsong Li Tom H. Cheung Naihe Jing Yi Arial Zeng | 2019 | Cell Research2019，29，3： | 2 |
您所在的机构暂未开通此部分的功能，请联系管理员