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40篇 您的检索式:作者名="LI WuJun"
    题名 作者 年代 出处 被引量
1Wheat genomic study for genetic improvement of traits in China显示文摘Bread wheat(Triticum aestivum L.)is a major crop that feeds 40%of the world’s population.Over the past several decades,advances in genomics have led to tremendous achievements in understanding the origin and domestication of wheat,and the genetic basis of agronomically important traits,which promote the breeding of elite varieties.In this review,we focus on progress that has been made in genomic research and genetic improvement of traits such as grain yield,end-use traits,flowering regulation,nutrient use efficiency,and biotic and abiotic stress responses,and various breeding strategies that contributed mainly by Chinese scientists.Functional genomic research in wheat is entering a new era with the availability of multiple reference wheat genome assemblies and the development of cutting-edge technologies such as precise genome editing tools,highthroughput phenotyping platforms,sequencing-based cloning strategies,high-efficiency genetic transformation systems,and speed-breeding facilities.These insights will further extend our understanding of the molecular mechanisms and regulatory networks underlying agronomic traits and facilitate the breeding process,ultimately contributing to more sustainable agriculture in China and throughout the world.Jun Xiao Bao Liu Yingyin Yao Zifeng Guo Haiyan Jia Lingrang Kong Aimin Zhang Wujun Ma Zhongfu Ni Shengbao Xu Fei Lu Yuannian Jiao Wuyun Yang Xuelei Lin Silong Sun Zefu Lu Lifeng Gao Guangyao Zhao Shuanghe Cao Qian Chen Kunpu Zhang Mengcheng Wang Meng Wang Zhaorong Hu Weilong Guo Guoqiang Li Xin Ma Junming Li Fangpu Han Xiangdong Fu Zhengqiang Ma Daowen Wang Xueyong Zhang Hong-Qing Ling Guangmin Xia Yiping Tong Zhiyong Liu Zhonghu He Jizeng Jia Kang Chong 2022Science China(Life Sciences)2022,65,9:9
2Cordycepin protects renal ischemia/reperfusion injury through regulating inflammation,apoptosis,and oxidative stress显示文摘Cordycepin(3-deoxyadenosine)is a naturally occurring adenosine analog and one of the bioactive constituents isolated from Cordyceps sinensis,species of the fungal genus Cordyceps.It has traditionally been a prized Chinese folk medicine for the human well-being.However,the actions of cordycepin against renal ischemia/reperfusion injury(/R)are still unknown.In the present study,rats were subject to VR and cordycepin was intragastrically administered for seven consecutive days before surgery to investigate the effects and mechanisms of cordycepin against renal/R injury.The test results of kidney and peripheral blood samples of experimental animals showed that cordycepin significantly decreased serum blood urea nitrogen and creatinine levels and markedly attenuated cell injury.Mechanistic studies showed that cordycepin significantly regulated inflammation,apoptosis,and oxidative stress.These data provide new insights for investigating the natural product with the nephroprotective effect against I/R,which should be developed as a new therapeutic agent for the treatment of I/R in the future.Feng Han Meng Dou Yuxiang Wang Cuixiang Xu Yang Li Xiaoming Ding Wujun Xue Jin Zheng Puxun Tian Chenguang Ding 2020Acta Biochimica et Biophysica Sinica2020,52,2:9
3Preparation and characterization of microcapsule containing epoxy resin and its self-healing performance of anticorrosion covering material显示文摘Microencapsulated healing agents that possess adequate strength,long shelf-life,and excellent bonding to the host material are required for self-healing materials. The in situ encapsulation method is demonstrated over an order of magnitude size reduction for the preparation of urea-formaldehyde(UF) capsules filled with a healing agent,a mixture epoxy resin of the epoxy 711 and E-51. Capsules with diameters as small as about 100 μm are achieved under the agitation rate of 800 r min-1. The capsules possess a uniform UF shell wall(4 μm average thickness) . By using the analysis of scanning electronic microscope(SEM) ,thermal analysis(TG-DTA) and FTIR,the characteristics of the microcapsules were investigated respectively. Successful self-healing has been demonstrated for anticorrosion covering materials with microcapsules.LIAO LePing ZHANG Wei XIN Yi WANG HongMei ZHAO Yang LI WuJun 2011Chinese Science Bulletin2011,56,4:8
4Assessment of different biomarkers provides valuable diagnostic standards in the evaluation of the risk of acute rejection显示文摘尖锐拒绝(AR ) 是为长期的拒绝在的一个强壮的风险因素肾移植接受者。AR 事件的精确、及时的诊断为疾病控制和预后是很重要的。因此,客观地评估了病人的有免疫力的地位在移植以后的治疗的地里是必要的。这纵的研究在外部血 mononuclear 房间( PBMC )和活体检视在 sera ,CD4+ T 房间的细胞内部的腺苷 triphosphate ( iATP )版本水平,和 granzyme B/perforin 表示调查了五 biomarkers ,人的白血球抗原( HLA ) -G5 和 sCD30 水平的实用性,总共肾的移植的 84 个案例的检测 AR 和 biomarkers 的决定。数据证明接受者与临床或证明的活体检视拒绝显著地增加了 CD4+ T 房间的 iATP 版本水平,并且提高了 sCD30,但是与稳定的接枝功能与个人相比在 sera 降低了 HLA-G5 水平。granzyme B 和 perforin 的表示层次也在 PBMC 和 AR 病人的接枝活体检视被提高。一起拿,我们鉴别 HLA-G5 的 sCD30, iATP, granzyme B, perforin,和 downregulation 的 upregulation 能提供珍贵诊断标准在 AR 的风险识别那些接受者。并且 iATP 可以比为预言接枝拒绝事件的其它是更好的 biomarker。Jin Zheng Xiaoming Ding Xiaohui Tian Zhankui Jin Xiaoming Pan Hang Yan Xinshun Feng Jun Hou Heli Xiang Li Ren Puxun Tian Wujun Xue 2012Acta Biochimica et Biophysica Sinica2012,44,9:8
5Probing the sulfur content in gasoline quantitatively with terahertz time-domain spectroscopy显示文摘Terahertz time-domain spectroscopy(THz-TDS)was used for the quantitative detection of sulfur content in gasoline.Models of chemo metrics methods and partial least squares(PLS)were built to measure THz-TDS and the sulfur content.All of the samples were divided into two parts.One part was used for calibration and the other one for validation.In order to evaluate the quality of the models,the correlation coefficient(R)and root-mean-square errors(RMSE)of calibration and validation models were calculated.The value of R and RMSE were close to 1 and 0 within acceptable levels,respectively,indicating that the combination of THz-TDS and PLS is a potential method for further quantitative detection.QIN FangLi LI Qian ZHAN HongLei JIN WuJun LIU HongLan ZHAO Kun 2014Science China(Physics,Mechanics & Astronomy)2014,57,7:8
6miR-124/IRE-1α affects renal ischemia/reperfusion injury by regulating endoplasmic reticulum stress in renal tubular epithelial cells显示文摘Acute kidney injury(AKI)refers to a clinical syndrome that occurs as a result of a rapid decline in renal function caused by multiple factors.Renal ischemia/reperfusion(/R)injury is one of the main causes of AKI and has a high incidence and mortality,However,the specific pathogenesis of renal I/R injury is still unclear.In recent years,a major breakthrough has been made in the study of endoplasmic reticulum stress(ERS)-mediated apoptosis in I/R injury.It has been reported that miRNAs play protective roles in ischemic/reperfused organs,but the molecular mechanisms have not been investigated deeply.In this study,the renal VR mouse model was used to explore the roles of miR-124 in ERS and in renal I/R injury.The western blot results showed that the expression levels of ERS-related proteins IRE-1α,XBP-1,and glucose-regulated protein 78(GRP78)were significantly increased in the IVR model group when compared with those in the control group.Meanwhile,qPCR results showed that miR-124 expression was decreased in the I/R injury model,and overexpression of miR-124 using miR-124 mimics effectively reduced the expression of ERS-related proteins and alleviated renal LR injury.In addition,luciferase reporter assay was performed,and the results showed that IRE 1αand miR-124 may have direct interaction.In conclusion,our data indicated that miR-124 was a negative regulator of ERS via binding to IRE-1α,ultimately conferring its protective effect on the kidney,which demonstrates the regulatory mechanism of miR-124 in renal I/R injury and provides new ideas and methods for the prevention and treatment of renal I/R injury.Chenguang Ding Meng Dou Yuxiang Wang Yang Li Ying Wang Jin Zheng Xiao Li Wujun Xue Xiaoming Ding Puxun Tian 2020Acta Biochimica et Biophysica Sinica2020,52,2:4
7Computation method of zero-stress state of pneumatic stressed membrane structure显示文摘The whole analysis process of pneumatic stressed membrane structure contains nine states and seven analysis processes.The zero-stress state is the corner-stone of analysis and design of pneumatic stressed structure,and has significant impact on the pre-stressed state and load state.According to the logical model of the whole numerical analysis process of pneumatic stressed structure,a numerical analysis method to solve the zero-stress state from the elasticized equilibrium state was firstly proposed,called linear compatibility matrix M-P inverse method.Firstly,the pneumatic membrane stressed structure was transferred into grid structure by using membrane link to simulate membrane surface.Secondly,on the basis of equilibrium matrix theory of pin joint structure and small deformation assumption,compatibility equation of system was established.Thirdly,the unstressed length and elongation of links were calculated from the tension and material parameters of elasticized equilibrium state.Finally,using compatibility matrix M-P inverse,the nodal displacement was calculated by solving compatibility equation,the configuration of zero-stress state could be obtained through reverse superposition,and the stress was released.According to the algorithm,the program was coded with MATLAB.The correctness and efficiency of this method were verified by several numerical examples,and it could be found that one elasticized equilibrium state corresponded to one configuration of the zero-stress state.The work has theoretical significance and practical guidance value for pneumatic membrane structural design.ZHAO JunZhao CHEN WuJun FU GongYi LI RuiXiong 2012Science China(Technological Sciences)2012,55,3:4
8Hypoxic preconditioning advances CXCR4 and CXCR7 expression by activating HIF-1α in MSCs显示文摘Hongbao Liu Wujun Xue Guanqun Ge Xiaohui Luo Yang Li Heli Xiang Xiaoming Ding Puxun Tian Xiaohui Tian 2010Biochemical and Biophysical Research Communications2010,,4:2
9Comparison of continual insulin or secretagogue treatment in type 2 diabetic patients with alternate insulin-secretagogue administration 显示文摘Hong Li Wujun Li Yao Gu 2009Diab Res Clin Pract2009,85,3:1
10Spatial Decision Support Proofs:Obtaining and Applying显示文摘Chaokui Li Wujun 2006GIM:International Magazine for Geomatics2006,,1:1
11Single set- up multiple delivery model of JIT system显示文摘Cao Wujun Hu Yujin Li Chenggang 2007Int J Adv Manuf Technol2007,33,:1
12Joint Boosting Feature Selection for Robust Face Recogni- tion显示文摘Xiao Rong Li Wujun Tian Yuandong 2006Computer Vision and Pattern Recognition2006,2,:1
13Paleomagnetic constraints on Paleogene-Neogene rotation and paleo-stress in the northern Qaidam Basin显示文摘Knowing the rotation and paleo-stress history in Qaidam Basin is a fundamental parameter to quantify the mechanism of intracontinental deformation in Tibetan Plateau.However,few studies have been conducted on tectonic rotation and stress evolution over long timescales in the Qaidam Basin.Here,we report new magnetic declination and the anisotropy of magnetic susceptibility(AMS)from a~52–7 Ma sequence of fluvial and lacustrine sediments in the Dahonggou(DHG)section in the northern Qaidam Basin.The magnetic declination revealed that the northern Qaidam Basin underwent a clockwise rotation 25.1°±8.6°during~33–17 Ma,followed by a counterclockwise rotation 16.9°±6.8°during~17–13.5 Ma.The AMS results showed that the“earliest deformation”fabrics were interrupted by the“pencil structure”fabrics in the intervals of~52–45 and~21–15 Ma.The interruption,synchronous with the marked deceleration of the India-Asia convergence rate,indicates pulse of strong tectonic compressive stress.In addition,the AMS results documented a transition in stress direction from S-N to SW-NE at~15 Ma,suggesting a kinematic shift in the northeastern TP.Our constraints on the rotation and stress from the northern Qaidam Basin support the two-stage evolution of the Altyn Tagh Fault(ATF).The fast-rate slip motion on the ATF during the early Oligocene caused the clockwise rotation in the northern Qaidam Basin;the second stage with enhanced thrusting since the middle Miocene caused extensive crustal shortening and dispersive NW-trending folds and faults in the Qaidam Basin and the northeastern TP.Ling SUN Junliang JI Bingshuai LI Xingbo LI Wujun WU Kexin ZHANG 2022Science China Earth Sciences2022,65,12:1
14Efficient syn- thesis of benzophenone derivatives in Lewis acid ionic liquids显示文摘Li Changzhi Liu Wujun Zhao Zongbao 2007Catal Commun2007,8,11:1
15Predictive value of hypothermic machine perfusion parameters combined perfusate biomarkers in deceased donor kidney transplantation显示文摘Background:Delayed graft function(DGF)is the main cause of renal function failure after kidney transplantation.This study aims at investigating the value of hypothermic machine perfusion(HMP)parameters combined with perfusate biomarkers on predicting DGF and the time of renal function recovery after deceased donor(DD)kidney transplantation.Methods:HMP parameters,perfusate biomarkers and baseline characteristics of 113 DD kidney transplantations from January 1,2019 to August 31,2019 in the First Affiliated Hospital of Xi’an Jiaotong University were retrospectively analyzed using univariate and multivariate logistic regression analysis.Results:In this study,the DGF incidence was 17.7%(20/113);The multivariate logistic regression results showed that terminal resistance(OR:1.879,95%CI 1.145-3.56)and glutathione S-transferase(GST)(OR=1.62,95%CI 1.23-2.46)were risk factors for DGF;The Cox model analysis indicated that terminal resistance was an independent hazard factor for renal function recovery time(HR=0.823,95%CI 0.735-0.981).The model combining terminal resistance and GST(AUC=0.888,95%CI:0.842-0.933)significantly improved the DGF predictability compared with the use of terminal resistance(AUC=0.756,95%CI 0.693-0.818)or GST alone(AUC=0.729,95%CI 0.591-0.806).Conclusion:According to the factors analyzed in this study,the combination of HMP parameters and perfusate biomarkers displays a potent DGF predictive value.Yuxi Qiao Chenguang Ding Yang Li Xiaohui Tian Puxun Tian Xiaoming Ding Heli Xiang Jin Zheng Wujun Xue 2022Chinese Medical Journal2022,,2:1
16Recombinase Polymerase Amplification(RPA)of Ca MV-35S Promoter and nos Terminator for Rapid Detection of Genetically Modified Crops显示文摘Chao Xu Liang Li Wujun Jin 2014International Journal of Molecular Sciences2014,15,18:1
17One-to-one communication in twisted cubes under restricted connectivity显示文摘Jianxi Fan Kenli Li Shukui Zhang Wujun Zhou Baolei Cheng 2010Frontiers of Computer Science in China2010,,:1
18Efficient Regeneration Potential is Closely Related to Auxin Exposure Time and Catalase Metabolism During the Somatic Embryogenesis of Immature Embryos in Triticum aestivum L显示文摘Maoyun She Guixiang Yin Jiarui Li Xing Li Lipu Du Wujun Ma Xingguo Ye 2013Molecular Biotechnology2013,,2:1
19Molecular characterization of the celiac disease epitope domains in α-gliadin genes in Aegilops tauschii and hexaploid wheats (Triticum aestivum L.)显示文摘Zhenze Xie Congyan Wang Ke Wang Shunli Wang Xiaohui Li Zhao Zhang Wujun Ma Yueming Yan 2010Theoretical and Applied Genetics2010,,7:1
20Efficient synthesis of benzophenone derivatives in Lewis acid ionic liquids显示文摘Li Changzhi Liu Wujun Zhao Zongbao(Kent) 2007Catalysis Communications2007,8,11:1
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