|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Function and regulation of self-reactive marginal zone B cells in autoimmune arthritis显示文摘Polyreactive 天生类型的 B 房间说明在圆周表示自我反应的许多 B 房间。这些 B 房间的不适当的规定可以是位于自体免疫的疾病下面的一个重要因素。这里,我们在导致骨胶原的关节炎(中央情报局) 的开发探索了自我反应的天生的 B 房间的影响,风湿性关节炎的一个鼠标模型。我们显示出那个脾的边缘的地区(MZ ) ,然而并非 B-1 B 房间在 naı 展出自发的 IgM 反应到自体同源的骨胶原 II; ¨ ve 老鼠。在有在完全的 Freund’ 的 heterologous 骨胶原 II 的免疫之上;骨胶原反应的 MZ B 房间很快扩展了的 s 助手,当 B-1 B 房间显示出谦虚反骨胶原回答时。MZ B 房间被像使用费的受体(TLR ) 容易激活 4 并且在 vitro,导致的增长和 cytokine 分泌物的 9-ligands,暗示 B 房间受体和 TLR 的那个双约会可以把有免疫力的反应提升到自我抗原。而且,告知骨胶原的 MZ B 房间显示出在 vivo 在 IgG 反骨胶原抗体的 vitro 和正式就职由血缘的 T 房间增长思考了的重要介绍抗原的能力。在 1 和 2 表明了的补充受体是缺乏的 MZ B 房间增加了增长和 cytokine 生产,当时 Fcγ房间的受体 IIb 缺乏导致增加的 cytokine 生产和抗原表示。在结论,我们的数据在中央情报局作为自体免疫的反应的开始者加亮自我反应的 MZ B 房间,在补充和 Fc 受体在在房间控制自我反应是相关的的地方。 | Anna-Karin E Palm Heike C Friedrich Anja Mezger Maya Salomonsson Linda K Myers Sandra Kleinau | 2015 | Cellular & Molecular Immunology2015，12，4： | 3 |
| 2 | Stem cells for cardiac repair: an introduction显示文摘Cardiovascular disease is a major cause of morbidity and mortality throughout the world. Most cardiovascular diseases, such as ischemic heart disease and cardiomyopathy, are associated with loss of functional cardiomyocytes. Unfortunately, the heart has a limited regenerative capacity and is not able to replace these cardiomyocytes once lost. In recent years, stem cells have been put forward as a potential source for cardiac regeneration. Pre-clinical studies that use stem cell-derived cardiac cells show promising results. The mechanisms,though, are not well understood, results have been variable, sometimes transient in the long term, and often without a mechanistic explanation.There are still severalmajor hurdles to be taken. Stem cell-derived cardiac cells should resemble original cardiac cell types and be able to integrate in the damaged heart. Integration requires administration of stem cell-derived cardiac cells at the right time using the right mode of delivery. Once delivered, transplanted cells need vascularization, electrophysiological coupling with the injured heart, and prevention of immunological rejection. Finally, stem cell therapy needs to be safe, reproducible, and affordable. In this review, we will give an introduction to the principles of stem cell based cardiac repair. | Bastiaan C du Pr(e) Pieter A Doevendans Linda W van Laake | 2013 | Journal of Geriatric Cardiology2013，10，2： | 2 |
| 3 | Akt Promotes Cell Survival by Phosphorylating and Inhibiting a Forkhead Transcription Factor显示文摘 | Anne Brunet Azad Bonni Michael J Zigmond Michael Z Lin Peter Juo Linda S Hu Michael J Anderson Karen C Arden John Blenis Michael E Greenberg | 1999 | Cell1999，，6： | 2 |
| 4 | Participation in Task Evaluation Procedures: The Effects of Influential Opinion Expression and Knowledge of Evaluation Criteria on Attitudes and Performance 显示文摘 | KANFER R SAWYER T EARLEY P C LINDA E A | 1986 | Social Justice Research1986，1，： | 1 |
| 5 | Long-term recovery of PCB-contaminated surface sediments at the Sangamo-westonl Twelvemile Creek/lake Hartwell Superfund Site 显示文摘 | Brenner Richard C Magar Victor S Ickes Jennifer A Foote Eric A Abbott James E Bingler Linda S Crecelius Eric A | 2004 | Environmental Science & Technology2004，38，8： | 1 |
| 6 | Growth inhibitory activity of extracts and compounds from Cimicifuga species on human breast cancer cells 显示文摘 | Linda S E Ye W C Kan H | 2008 | Phytomedicine2008，15，67： | 1 |
| 7 | An ecological study of the association of environmental chemicals on breast incidence in Texas显示文摘 | Yvonne M C Linda S H David M E | 2005 | Breast Cancer Res Treat2005，92，2： | 1 |
| 8 | Transaction Cost Economics, Resource Dependence Theory, and Customer-supplier Relationships 显示文摘 | Robert C F Linda F E Kenneth J H William L J | 2006 | Industrial and Corporate Change2006，15，3： | 1 |
| 9 | Pulmonary Administration of a Water-Soluble Curcumin Complex Reduces Severity of Acute Lung Injury显示文摘 | Suresh Madathilparambil V Wagner Matthew C Rosania Gus R Stringer Kathleen A Min Kyoung Ah Risler Linda Shen Danny D Georges George E Reddy Aravind T Parkkinen Jaakko Reddy Raju C | 2012 | EN2012，，： | 1 |
| 10 | Benefits of psychosocial oncology care:improved quality of life and medical cost offset显示文摘 | LINDA E C BARRY D B | 2003 | Health Qual Life Outcomes2003，1，8： | 1 |
| 11 | Product performance and consumer satisfaction: a new concept 显示文摘 | SWAN J E LINDA J C | 1976 | Journal of Marketing1976，40，4： | 1 |
| 12 | An investigation of vapor deposited boron rich carbon A novel graphite like material I: The structure of BCx (C6B) thin films 显示文摘 | Charles T H Linda E J Carl C | 1999 | Carbon1999，37，2： | 1 |
| 13 | An investigation of vapor deposited boron rich carbon-a novel graphite-like material-part Ⅰ:the structure of BCx(C6B) thin films显示文摘 | CHARLES T H LINDA E J CARL C | 1999 | Carbon1999，37，： | 1 |
| 14 | Effect of regional gene therapy with bone morphogenetic protein-2-producing bone marrow cells on spinal fusion in rats显示文摘 | Wang C Jeffrey E Linda EA | 2003 | J Bone Joint Surg(Am)2003，85，5： | 1 |
| 15 | Nasal Reconstruction after Malignant Tumor Resection:An Algorithm For Treatment显示文摘 | Sanne E M Linda M Peter C L | | 0，，01： | 1 |
| 16 | Geologic Controls on Radon显示文摘 | Linda C S Gundersen | 1992 | The Geological Society of America1992，，： | 1 |
| 17 | Probiotics and prebiotics in dietetics practice显示文摘 | LINDA C MARY E | 2008 | J Am Diet Assoc2008，108，： | 1 |
| 18 | Transgenic pollen harms monarch larvae 显示文摘 | John E L Linda S R Maureen E C | 1999 | Nature1999，399，： | 1 |
| 19 | Bactericidal and Cytotoxic Effects of Chloramine-T onWound Pathogens and Human Fibroblasts In Vitro 显示文摘 | Luther C Kloth Joseph E Berman Linda J | 2007 | Advances In Skin Wound Care2007，6，20： | 1 |
| 20 | 查看详情显示文摘 | Hoover R N Hyer M Pfeiffer R M Adam E Bond B Cheville A L Colton T Hartge P Hatch E E Herbst A L Karlan B Y Kaufman R Noller K L Palmer J R Stanley J Robert C R Strohsnitter W Linda T E Troisi R N | | 0，，14： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员