|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Effect of oral epidermal growth factor on mucosal healing in rats with duodenal ulcer显示文摘AIM: To investigate the effect of epidermal growth factor (EGF) on mucosal healing in rats with duodenal ulcer.METHODS: Male Sprague-Dawley rats were randomly divided into sham operation without EGF, sham operation with EGF, duodenal ulcer without EGF, or duodenal ulcer with EGF groups. Additionally, normal rats without operation served as the control group. Duodenal ulcer was induced in rats by 300 mL/L acetic acid. Rats with EGF were orally administered at a dose of 60 μg/kg/day in drinking water on the next day of operation (day 1). Healing of duodenal ulcer was detected by haematoxylin and eosin staining. Cell growth of damaged mucosa was determined by the contents of nucleic acids and proteins. The level of EGF in duodenal mucosa was measured by ELISA.RESULTS: The pathological results showed that duodenal ulcer rats with EGF improved mucosal healing compared with those without EGF after day 5. Duodenal ulcer rats with EGF significantly increased duodenal DNA content compared with those without EGF on day 15 (6.44±0.54mg/g VS 1.45±0.52 mg/g mucosa, P<0.05). Duodenal RNA and protein contents did not differ between duodenal ulcer rats with and without EGF during the experimental period.Sham operation and duodenal ulcer rats with EGF significantly increased duodenal mucosal EGF content compared with those without EGF on day 5 (76.0±13.7 ng/g VS 35.7±12.9ng/g mucosa in sham operation rats, and 68.3±10.9 ng/gVS 28.3±9.2 ng/g mucosa in duodenal ulcer rats, P<0.05).CONCLUSION: Oral EGF can promote mucosal healing of the rats with duodenal ulcer by stimulating mucosal proliferation accompanied by an increase in mucosal EGF content. | Jane CJ Chao Kuo-Yu Liu Sheng-Hsuan Chen Chia-Lang Fang Chih-Wei Tsan | 2003 | World Journal of Gastroenterology2003，9，10： | 9 |
| 2 | 放射性颌骨骨坏死拔牙的危险因素及作用:国家层面的队列研究显示文摘该文旨在研究接受放疗并发生放射性颌骨骨坏死(ORNJ)的头颈癌患者的相关危险因素,尤其是接受某种药物治疗后及牙的变化情况。23,527例头颈癌患者纳入研究,Cox比例风险模型用于危险因素分析。结果:ORNJ的总发生率为3.93/100人/年,颊癌患者发生ORNJ的风险最高。 | Wang TH Liu CJ Chao TF 张凌 | 2017 | 中国口腔颌面外科杂志2017，15，3： | 4 |
| 3 | Risk factors for ICU mortality in critically ill patients 显示文摘 | Chen YC Lin SF Liu CJ | 2001 | Fomos Med Assoc2001，100，10： | 1 |
| 4 | Hepatitis B genotypes and precore/basal core promoter mutants in HBeAg-negativer chronic hepatitis B显示文摘 | Lin CL Liao LY Liu CJ | 2002 | J Gastroenterol2002，37，： | 1 |
| 5 | Pegylated interferon-alpha-2a plus ribavirin for treatment-naive Asian patients with hepatitis C virus genotype 1 infeetion: a multieenter, randomized eontrolled trial显示文摘 | Liu CH Liu CJ Lin CL | 2008 | Clin Infect Dis2008，47，10： | 1 |
| 6 | Risk stratification of hepatocellular carcinoma in hepatitis B virus e antigen-negative carriers by combining viral biomarkers显示文摘 | Tseng TC Liu CJ Chen CL | | 0，，04： | 1 |
| 7 | miR-24 up-regulation in oral carcinoma:positive association from clinical and in vitro analysis显示文摘 | Lin SC Liu CJ Lin JA | | 0，，3： | 1 |
| 8 | Hypermethylation of RASSF1A and BLU tumor suppressor genes in non-small cell lung cancer:implications for tobacco smoking during adolescence显示文摘 | Marsit CJ Kim DH Liu M | 2005 | Int J Cancer2005，114，2： | 1 |
| 9 | Vascular endothelial growth factor is an in vivo survival factor for tumor endothelium in a murine model of colorectal carcinoma liver metastases 显示文摘 | BRUNS CJ LIU W DAVIS DW | 2000 | Cancer2000，89，3： | 1 |
| 10 | Role of central interleukin- 1 in stress- induced hypertension and footshock- induced- analgesia in rats显示文摘 | Zou CJ Liu JD Zhou YC | 2001 | Neurosci Lett2001，311，1： | 1 |
| 11 | Mixed hepatitis B virus genotype infection:the more,the worse?显示文摘 | Liu CJ Kao JH Chen DS | 2006 | Hepatology2006，44，3： | 1 |
| 12 | Global perspective on the natural his- tory of chronic hepatitis B: role of hepatitis B virus genotypes A to J显示文摘 | Liu CJ Kao JH | 2013 | Semin Liver Dis2013，33，2： | 1 |
| 13 | Functional polymorphism in NFKB1 promoter is related to the risks of oral squamous cell carcinoma occurring on older male areca(betel) chewers显示文摘 | Lin SC Liu CJ Yeh WI | 2006 | Cancer Lett2006，243，1： | 1 |
| 14 | A Bayesian Discriminating Features Method for Face Detection显示文摘 | LIU CJ | 2003 | IEEE Transactions Pattern Analysis and Machine Intelligence2003，25，6： | 1 |
| 15 | 显示文摘 | Bruns CJ Liu W Davis DW | 2000 | Cancer2000，89，3： | 1 |
| 16 | Natural course and treatment of hepatitis D virus infection显示文摘 | Hsieh TH Liu CJ Chen DS | 2006 | J Formos Med Assoc2006，105，11： | 1 |
| 17 | Survival analysis in systemic lupus cry- thematosus patients on maintenance dialysis: a nationwide population- based study in Taiwan显示文摘 | Chang YS Liu CJ Wu TH | 2013 | Rheumatology (Oxford)2013，52，1： | 1 |
| 18 | Determinants of spontaneous surface antigen loss in hepatitis B e antigen-negative patients with a low viral load 显示文摘 | Tseng TC Liu CJ Yang HC | 2012 | Hepatology2012，551，： | 1 |
| 19 | 17beta- Estradiol inhibits mesenchymal stem cells-induced human AGS gastric cancer cell mobility via suppression of CCLS- Src/Cas/Paxillin signaling pathway显示文摘 | Kuo CH Liu CJ Lu CY | 2014 | Int J Med Sci2014，11，1： | 1 |
| 20 | Vascular endothelial growth factor is an in vivo survival factor for tumor endothelium in a murine model of colorectal carcinoma liver metastasis显示文摘 | Liu W Davis DW | 2000 | Cancer2000，89，3： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员