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| 1 | Geological characteristics and metallogenic significance of the Devonian intermediate-basic volcanic rocks in the Dachang deposit, Guangxi Zhuang Autonomous Region显示文摘Recently discovered intermediate-basic volcanic rocks in the Devonian strata at Dachang, Guangxi Zhuang Autonomous Region are dominated by basalts and andesites. Most of them belong to the calc-alkali and alkali series. Petrology and geochemistry data indicate that the volcanic rocks may be formed in a continental rift environment. The volcanic rocks are in conformable contact with the overlying and underlying wall rocks, with such typical sedimentary structures as laminated and striped ones, and the host rocks of the volcanic rocks contain lots of marine fossils such as tentaculite. Many pieces of evidence indicate that the eruption environment of the volcanic rocks is a sea-facies one. The volcanic rocks are of the LREE-enrichment type, with high ratios of light rare-earth elements to heavy rare-earth elements. In addition, they display moderately negative δEu anomalies and moderately negative δCe anomalies with a higher degree of LREE and HREE fractionation. Through the Q-cluster analysis of the REE samples, it is indicated that the ores have a closer relation with the layered volcanic rocks, and also possess a certain inheritance-consistency relationship with the layered volcanic rocks. The source of ore-forming materials may be related with volcanism. It is proposed that the ore deposit in the study area should be genetically explained as the result of marine volcano-sedimentary exhalation of hot water and late superposition-reworking. | YAN Yongfeng LIU Chenming QIN Dexian JIANG Kai | 2013 | Chinese Journal Of Geochemistry2013，32，1： | 9 |
| 2 | Whole-Process Pollution Control for Cost-Effective and Cleaner Chemical Production A Case Study of the Tungsten Industry in China显示文摘In this research,a methodology named whole-process pollution control(WPPC)is demonstrated that improves the effectiveness of process optimization.This methodology considers waste/emission treatment as a step of the whole production process with respect to the minimization of cost and environmental impact for the whole process.The following procedures are introduced in a WPPC process optimization:①a material and energy flow investigation and optimization based on a systematic understanding of the distribution and physiochemical properties of potential pollutants;②a process optimization to increase the utilization efficiency of different elements and minimize pollutant emissions;and③an evaluation to reveal the effectiveness of the optimization strategies.The production of ammonium paratungstate was chosen for the case study.Two factors of the different optimization schemes-namely the cost-effectiveness factor and the environmental impact indicator-were evaluated and compared.This research demonstrates that by considering the nature of potential pollutants,technological innovations,economic viability,environmental impacts,and regulation requirements,WPPC can efficiently optimize a metal production process. | Hongbin Cao He Zhao Di Zhang Chenming Liu Xiao Lin Yuping Li Pengge Ning Jiajun Sun Yi Zhang Zhi Sun | 2019 | Engineering2019，5，4： | 7 |
| 3 | Deficiency of Mouse CD4^+CD25^+Foxp3^+ Regulatory T Cells in Xenogeneic Pig Thymus-Grafted Nude Mice Suffering from Autoimmune Diseases显示文摘Xenogeneic thymus transplantation can efficiently induce specific immune tolerance to donor antigens in athymic recipients. However, many nude mice suffer from autoimmune diseases (AID) for over 10 weeks after xenogeneic thymus transplantation. CD4+CD25+Foxp3+ regulatory T (Treg) cells were recently determined to play a pivotal role in keeping immune tolerance in humans and mice. Thus, we investigated this subpopulation of Treg cells in the periphery of pig thymus-grafted nude mice suffering from AID. Our results showed that the expression of Foxp3, CTLA-4 and GITR on mouse CD4+CD25+ T cells and the ratio of CD4+CD25+Foxp3+ Treg cells to CD4+ T cells were significantly decreased in the periphery of pig thymus-grafted nude mice suffering from AID, compared with healthy pig or mouse thymus-grafted nude mice. Furthermore, mouse CD4+CD25+ T cells in pig thymus-grafted nude mice suffering from AID showed more severe deficiency in immunosuppressive function compared with the counterpart in xenogeneic pig or syngeneic thymus-grafted nude mice without AID. Thus, the decreased frequency, altered phenotype and functional deficiency of mouse CD4+CD25+ Treg cells in pig thymus-grafted nude mice may contribute to the development of AID in this model. | Baojun Zhang Chenming Sun Yanyan Qu Aijun Zhang Jun Liu Lianjun Zhang Zeqing Niu Yong Zhao | 2008 | Cellular & Molecular Immunology2008，5，5： | 6 |
| 4 | A multi-axis robot-based bioprinting system supporting natural cell function preservation and cardiac tissue fabrication显示文摘Despite the recent advances in artificial tissue and organ engineering,how to generate large size viable and functional complex organs still remains as a grand challenge for regenerative medicine.Three-dimensional bioprinting has demonstrated its advantages as one of the major methods in fabricating simple tissues,yet it still faces difficulties to generate vasculatures and preserve cell functions in complex organ production.Here,we overcome the limitations of conventional bioprinting systems by converting a six degree-of-freedom robotic arm into a bioprinter,therefore enables cell printing on 3D complex-shaped vascular scaffolds from all directions.We also developed an oil bath-based cell printing method to better preserve cell natural functions after printing.Together with a self-designed bioreactor and a repeated print-and-culture strategy,our bioprinting system is capable to generate vascularized,contractible,and long-term survived cardiac tissues.Such bioprinting strategy mimics the in vivo organ development process and presents a promising solution for in vitro fabrication of complex organs. | Zeyu Zhang Chenming Wu Chengkai Dai Qingqing Shi Guoxin Fang Dongfang Xie Xiangjie Zhao Yong-Jin Liu Charlie CLWang Xiu-Jie Wang | 2022 | Bioactive Materials2022，7，12： | 4 |
| 5 | Distinct synergetic effects in the ozone enhanced photocatalytic degradation of phenol and oxalic acid with Fe^(3+)/TiO_2 catalyst显示文摘In this work, phenol and oxalic acid(OA) degradation in an ozone and photocatalysis integrated process was intensively conducted with Fe^(3+)/TiO_2 catalyst. The ferrioxalate complex formed between Fe^(3+) and oxalate accelerated the removal of OA in the ozonation, photolysis and photocatalytic ozonation process, for its high reactivity with ozone and UV. Phenol was degraded in ozonation and photolysis with limited TOC removal rates, but much higher TOC removal was achieved in photocatalytic ozonation due to the generation of ·OH. The sequence of UV light and ozone in the sequential process also influences the TOC removal, and ozone is very powerful to oxidize intermediates catechol and hydroquinone to maleic acid. Fenton or photo-Fenton reactions only played a small part in Fe^(3+)/TiO_2catalyzed processes, because Fe^(3+) was greatly reduced but not regenerated in many cases.The synergetic effect was found to be highly related with the property of the target pollutants. Fe^(3+)/TiO_2 catalyzed system showed the highest ability to destroy organics, but the TiO_2 catalyzed system showed little higher synergy. | Yongbing Xie Yingying Chen Jin Yang Chenming Liu He Zhao Hongbin Cao | 2018 | Chinese Journal of Chemical Engineering2018，26，7： | 3 |
| 6 | Application of triple potential step amperometry method for quantitative electroanalysis显示文摘A novel quantitative electroanalysis method, triple potential step amperometry (TPSA), was developed and explained with an example of nitrobenzene analyzing in water. The selectivity of TPSA was im- proved by controlling the potential step within a narrow interval and using enzyme-modified electrode, the narrow potential step makes the method avoid most interferents, and enzyme-modified electrode can enhance the response of target substance selectively. The peak area was investigated for quanti- tative calibration, such as nitrobenzene concentration showing a linear relation with the peak area, with the correlation coefficients being 0.9995. The t-test and F-test were applied to evaluating the reliability of TPSA, the results showed that there was no evidence of systematic error for TPSA, and the method was of no significant difference from CV. The merit of fast detecting and few potential changing times make the TPSA suitably applicable to low-cost automatic monitoring equipments. | LIU ChenMing CAO HongBin LI YuPing ZHANG Yi | 2007 | Chinese Science Bulletin2007，52，20： | 2 |
| 7 | Investigation of Controlling Factors for Growth in Stromatolites of the Tieling Formation,Jixian,Tianjin显示文摘Objective The Yan–Liao Aulacogen is located in the northern SinoKorean Plate,buried under huge Meso–Neoproterozoic sedimentation,and is widely distributed in Beijing,Tianjin and Hebei.In these strata,several microbial mats occur,represented by four stromatolite assemblages within the Upper Precambrian stratotype section at Jixian,Tianjin. | HUANG Min LU Chenming JIANG Zikun LIU Benpei CHU Zhihui ZHAO Yanxu | 2017 | Acta Geologica Sinica(English Edition)2017，91，1： | 2 |
| 8 | Threshold voltage model for deep-submicrometer MOSFETs显示文摘 | Liu Zhihong Hu Chenming Huang Jianhui | 1993 | IEEE Transactions on Electron Devices1993，40，1： | 1 |
| 9 | Genetic and Breeding Progress Analysis on Five Pure Lines of Dahen Broiler显示文摘To timely modify breeding scheme and improve selection efficiency of Dahen broiler,genetic and breeding progress analysis on five pure lines was conducted. The results showed that the selection on breeding goal traits of each line was effective since 14 generations,especially the selection on growth traits did not cause adverse influence on reproductive performance. After the 6 thgeneration,main performances of each line maintained in higher level,but the breeding progress obviously declined. It illustrated that current breeding means was effective for maintaining and consolidating breeding goal traits of Dahen broiler,and it should timely adjust breeding scheme to obtain more genetic progress. | Chaowu YANG Huarui DU Zengrong ZHANG Mohan QIU Chunlin YU Lan LIU Xiaoyu JIANG Bo XIA Chenming HU Xiaoyan SONG Xia XIONG Li YANG Han PENG Qingyun LI Xiaosong JIANG | 2018 | Agricultural Biotechnology2018，7，5： | 1 |
| 10 | A New Solar Broadband Radio Spectrometer (SBRS) in China显示文摘 | Qijun Fu Huirong Ji Zihai Qin Zhicai Xu Zhiguo Xia Hongao Wu Yuying Liu Yihua Yan Guangli Huang Zhijun Chen Zhenyu Jin Qijun Yao Congling Cheng Fuying Xu Min Wang Libei Pei Shanhuai Chen Guo Yang Chenming Tan Suobiao Shi | 2004 | Solar Physics2004，，1： | 1 |
| 11 | Characterization and prevention of interfacial crud produced during the extraction of vanadium and chromium by primary amine显示文摘 | Pengge Ning Hongbin Cao Chenming Liu Yuping Li Yi Zhang | 2009 | Hydrometallurgy2009，，1： | 1 |
| 12 | Threshold voltage model for deep-submicrometer MOSFET 's显示文摘 | Zhi-Hong Liu Chenming Hu Jian-Hui Huang | 1993 | IEEE Trans Electron Devices1993，40，1： | 1 |
| 13 | Characterization and prevention of interfacial crud produced during the ex-traction of vanadium and chromium by primary amine显示文摘 | Ning Pengge Cao Hongbin Liu Chenming | 2009 | Hydrometallurgy2009，97，12： | 1 |
| 14 | Threshold voltage model for deep-submierometer MOSFET's 显示文摘 | Liu Zhihong Hu Chenming Huang Jianhui | 1993 | IEEE Transactions on Electron De- vices1993，40，1： | 1 |
| 15 | Report on the Breeding of Dahen 799 Broilers显示文摘[Objectives]This study was conducted to improve the production efficiency of dark-shank partridge-like plumage high-quality broilers and ensure animal welfare,so as to meet the development needs of China’s yellow-feather broiler industry.[Methods]Sichuan Animal Science Academy and Sichuan Dahen Poultry Breeding Co.,Ltd.formed a joint breeding research team.The team bred Dahen 799 broiler complete set line with local chicken breeds as the main material and improving production efficiency,stabilizing meat quality and flavor and achieving autosexing of chicks as the main breeding goals by modern poultry breeding technologies,after 10 years and 8 generations.[Results]The Dahen 799 broiler complete set line was approved by National Commission of Livestock and Poultry Genetic Resources in December 2020.The 66-week-old egg production of the breed reached 189 eggs.For the commercial generation,cocks and hens showed 10-week-old weights of 2668 and 2269 g,respectively;the feed conversion ratio was 2.26-2.35;the survivability was 96.7%-97.2%;and the average intramuscular fat contents of cocks and hens were in the range of 1.8%-2.1%,and the inosinic acid contents were in the range of 2.3-3.2 mg/g.The production performance and meat flavor of Dahen 799 broilers were better than Dahen 699 broilers,Sichuan mountainous bone-black chickens and two other social breeds.Compared with Sichuan mountainous bone-black chickens,the egg production at the age of 66 weeks increased by 47 eggs;the average weight of cocks and hens of the commercial generation at 10 weeks increased by 45.21%;and the autosexing rate of chicks of the commercial generation reached 99.3%.[Conclusions]Dahen 799 broilers have the advantages of good production performance,high feed conversion ratio and excellent meat flavor and the characteristic of autosexing which other breeds do not have,and can fully meet the industrial development needs of dark shanks and partridge-like plumage broilers. | Chaowu YANG Chunlin YU Mohan QIU Zengrong ZHANG Chenming HU Huarui DU Qingyun LI Xia XIONG Shiliang ZHU Siyang LIU Xiaosong JIANG | 2022 | Agricultural Biotechnology2022，11，3： | 0 |
| 16 | Josephin domain containing 2(JOSD2)promotes lung cancer by inhibiting LKB1(Liver kinase B1)activity显示文摘Non-small cell lung cancer(NSCLC)ranks as one of the leading causes of cancer-related deaths worldwide.Despite the prominence and effectiveness of kinase-target therapies in NSCLC treatment,these drugs are suitable for and beneficial to a mere~30%of NSCLC patients.Consequently,the need for novel strategies addressing NSCLC remains pressing.Deubiquitinases(DUBs),a group of diverse enzymes with well-defined catalytic sites that are frequently overactivated in cancers and associated with tumorigenesis and regarded as promising therapeutic targets.Nevertheless,the mechanisms by which DUBs promote NSCLC remain poorly understood.Through a global analysis of the 97 DUBs’contribution to NSCLC survival possibilities using The Cancer Genome Atlas(TCGA)database,we found that high expression of Josephin Domain-containing protein 2(JOSD2)predicted the poor prognosis of patients.Depletion of JOSD2 significantly impeded NSCLC growth in both cell/patient-derived xenografts in vivo.Mechanically,we found that JOSD2 restricts the kinase activity of LKB1,an important tumor suppressor generally inactivated in NSCLC,by removing K6-linked polyubiquitination,an action vital for maintaining the integrity of the LKB1-STRAD-MO25 complex.Notably,we identified the first small-molecule inhibitor of JOSD2,and observed that its pharmacological inhibition significantly arrested NSCLC proliferation in vitro/in vivo.Our findings highlight the vital role of JOSD2 in hindering LKB1 activity,underscoring the therapeutic potential of targeting JOSD2 in NSCLC,especially in those with inactivated LKB1,and presenting its inhibitors as a promising strategy for NSCLC treatment. | Tao Yuan Chenming Zeng Jiawei Liu Chenxi Zhao Fujing Ge Yuekang Li Meijia Qian Jiamin Du Weihua Wang Yonghao Li Yue Liu Xiaoyang Dai Jianya Zhou Xueqin Chen Shenglin Ma Hong Zhu Qiaojun He Bo Yang | 2024 | Signal Transduction and Targeted Therapy2024，9，2： | 0 |
| 17 | Modulation of Microstructure and Charge Transport in Polymer Monolayer Transistors by Solution Aging显示文摘A few monolayers of organic semiconductors adjacent to the dielectric layer are of vital importance in organic field-effect transistors due to their dominant role in charge transport.In this report,the 2-nm-thick polymer monolayers based on poly(3-hexylthiophene)with different molecular weights(M_(n))were fabricated using dip-coating technique.During the monolayer(solid state)formation from the solution,a disorder-to-order transition of polymer conformation is observed through UV-vis absorption measurement.Meanwhile,high Mn polymer monolayer generates higher crystalline fibrillar microstructure than the low Mn one due to the strongerπ–πintermolecular packing between polymers.More importantly,the solution aging procedure is utilized to further improve the morphology of polymer monolayers.It is obvious that after aging for 6 d,both fiber dimension and density as well as conjugation length are significantly increased under the same processing conditions in comparison to the fresh solution,and consequently the field-effect mobilities are remarkably enhanced by 2—4 times.Note that the maximum mobility of 0.027 cm2·V^(–1)·s^(–1)is among the highest reported values for poly(3-hexylthiophene)monolayer transistors.These results demonstrate a simple but powerful strategy for boosting the device performance of polymer monolayer transistors. | Xuemei Lin Ruochen Liu Chenming Ding Junyang Deng Yifu Guo Shibing Long Ling Li Mengmeng Li | 2021 | Chinese Journal of Chemistry2021，39，11： | 0 |
| 18 | Comparative Analysis of Slaughter Performance and Meat Flavor Traits of Quality Chicken under Cage Rearing and Free-range Farming Conditions显示文摘[Objective]The paper was to compare the slaughter performance and meat flavor of quality chicken under cage rearing and free-range farming conditions.[Method]A total of 4001-day-old cocks,S07 line cultivated by Sichuan Dahen Poultry Breeding Co.,Ltd.(bred for 4 succes-sive generations),were kept in cages until the end of 5 weeks of age,which were then divided into cage rearing and free-range farming groups.All cocks were fed with the same diet,and slaughter tests and meat quality analysis were carried out at the end of 10 and 22 weeks of age,respectively.[Result]The live weight,carcass weight and abdominal fat percentage in cage rearing group were significantly higher than those in free-range farming group(P<0.01),and the percentage of half-eviscerated yield and percentage of eviscerated yield in cage rearing group were significantly higher than those in free-range farming group(P<0.05),but there were no significant differences in dressing percentage,percentage of leg muscle and per-centage of breast muscle.The intramuscular fat(IMF)content and muscle fiber density of chicken in cage rearing group were significantly higher than those in free-range farming group(P<0.01),but there was no significant difference in inosinic acid(IMP)content.The content of IMF and IMF increased with the increase of feeding age,but the deposition rate of intramuscular fat was higher than that of IMF in late feeding period.[Conclusion]The study will provide reliable guidance for production and market consumption of high quality chicken. | Yang Chaowu Yu Chunlin Qiu Mohan Zhang Zengrong Hu Chenming Xiong Xia Xia Bo Peng Han Song Xiaoyan Chen Jialei Zhu Shiliang Liu Siyang Du Huarui Li Qingyun | 2022 | Animal Husbandry and Feed Science2022，14，1： | 0 |
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