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| 1 | A 0.423THz Second Harmonic Gyrotron Oscillator显示文摘 | YAN Yang LI Xiaoyun YUAN Xuesong FU Wenjie LIU Diwei | 2013 | Chinese Journal of Electronics2013,22,2: | 2 |
| 2 | AHA1 upregulates IDH1 and metabolic activity to promote growth and metastasis and predicts prognosis in osteosarcoma显示文摘Osteosarcoma(OS)is the most common primary malignant bone tumor in children and adolescents.Although activator of HSP90 ATPase activity 1(AHA1)is reported to be a potential oncogene,its role in osteosarcoma progression remains largely unclear.Since metabolism reprogramming is involved in tumorigenesis and cancer metastasis,the relationship between AHA1 and cancer metabolism is unknown.In this study,we found that AHA1 is significantly overexpressed in osteosarcoma and related to the prognosis of osteosarcoma patients.AHA1 promotes the growth and metastasis of osteosarcoma both in vitro and in vivo.Mechanistically,AHA1 upregulates the metabolic activity to meet cellular bioenergetic needs in osteosarcoma.Notably,we identifed that isocitrate dehydrogenase 1(IDH1)is a novel client protein of Hsp90 AHA1.Furthermore,the IDH1 protein level was positively correlated with AHA1 in osteosarcoma.And IDH1 overexpression could partially reverse the effect of AHA1 knockdown on cell growth and migration of osteosarcoma.Moreover,high IDH1 level was also associated with poor prognosis of osteosarcoma patients.This study demonstrates that AHA1 positively regulates IDH1 and metabolic activity to promote osteosarcoma growth and metastasis,which provides novel prognostic biomarkers and promising therapeutic targets for osteosarcoma patients. | Diwei Zheng Weihai Liu Wenlin Xie Guanyu Huang Qiwei Jiang Yang Yang Jiarong Huang Zihao Xing Mengling Yuan Mengning Wei Yao Li Junqiang Yin Jingnan Shen Zhi Shi | 2021 | Signal Transduction and Targeted Therapy2021,6,2: | 1 |
| 3 | Direction controllable inverse transition radiation from the spatial dispersion in a graphene-dielectric stack显示文摘Transition radiation(TR) induced by electron–matter interaction usually demands vast accelerating voltages, and the radiation angle cannot be controlled. Here we present a mechanism of direction controllable inverse transition radiation(DCITR) in a graphene-dielectric stack excited by low-velocity electrons. The revealed mechanism shows that the induced hyperbolic-like spatial dispersion and the superposition of the individual bulk graphene plasmons(GPs) modes make the fields, which are supposed to be confined on the surface, radiate in the stack along a special radiation angle normal to the Poynting vector. By adjusting the chemical potential of the graphene sheets, the radiation angle can be controlled. And owing to the excitation of bulk GPs, only hundreds of volts for the accelerating voltage are required and the field intensity is dramatically enhanced compared with that of the normal TR. Furthermore, the presented mechanism can also be applied to the hyperbolic stack based on semiconductors in the infrared region as well as noble metals in the visible and ultraviolet region.Accordingly, the presented mechanism of DCITR is of great significance in particle detection, radiation emission,and so on. | SEN GONG MIN HU ZHENHUA WU HANG PAN HAOTIAN WANG KAICHUN ZHANG RENBIN ZHONG JUN ZHOU TAO ZHAO DIWEI LIU WEI WANG CHAO ZHANG SHENGGANG LIU | 2019 | Photonics Research2019,7,10: | 1 |
| 4 | Mode Competition of Low Voltage Backward Wave Oscillator near 500 GHz with Parallel Multi-Beam显示文摘A backward wave oscillator with parallel multiple beams and multi-pin slow-wave structure(SWS)operating at the frequency above 500 GHz is studied.Both the cold-cavity dispersion characteristics and CST Particle Studio simulation results reveal that there are obvious mode competition problems in this kind of terahertz source.Considering that the structure of the multi-pin SWS is similar to that of two-dimensional photonic crystals,we introduce the defects of photonic crystal with the property of filtering into the SWS to suppress high-order modes.Furthermore,a detailed study of the effect of suppressing higher-order modes is carried out in the process of changing location and arrangement pattern of the point defects.The stable,single-mode operation of the terahertz source is realized.The simulation results show that the ratio of the output peak power of the higher-order modes to that of the fundamental mode is less than 1.9%.Also,the source can provide the output peak power of 44.8 mW at the frequency of 502.2 GHz in the case of low beam voltage of 4.7 kV. | Xiaoyan ZHAO Jincheng HUI Haoran ZHANG Sidou GUO Yuming FENG Lin TANG Kaichun ZHANG Diwei LIU | 2024 | Chinese Journal of Electronics2024,33,2: | 0 |
| 5 | Coupling Enhancement of THz Metamaterials Source with Parallel Multiple Beams显示文摘In this paper,we propose a terahertz radiation source over the R-band(220-325 GHz)based on metamaterials(MTMs)structure and parallel multiple beams.The effective permittivity and permeability of the slow-wave structure can be obtained through the S-parameter retrieval approach,using numerical simulation.Additionally,the electromagnetic properties of the MTMs structure are analyzed,including the dispersion and the coupling impedance.Furthermore,we simulate the beam-wave interaction of the backward oscillator(BWO)with MTMs structure and parallel multiple beams by 3-D particle-in-cell code.It is observed that parallel multiple beams can highly enhance the beam-wave interaction and greatly enlarge the output power.These results indicate that the saturated(peak)output power is approximately 63W with the efficiency of roughly 6%at the operating frequency of 231 GHz,under the beam voltage of 35 kV and total current of 30 mA(6-beam)respectively.Meanwhile,the BWO can generate power of 10-80 W in the tunable frequency of 220-240 GHz. | ZHANG Kaichun FENG Yuming ZHAO Xiaoyan HU Jincheng XIONG Neng GUO Sidou TANG Lin LIU Diwei | 2023 | Chinese Journal of Electronics2023,32,4: | 0 |
| 6 | Water-soluble organic matter with various polarities in PM_(2.5) over Xi'an,China:Abundance,functional groups,and light absorption显示文摘Humic-like substances(HULIS)are a major component of brown carbon and consequently play a major role in climate change.In this study,70 PM_(2.5) samples were collected from Xi'an in winter 2019 and summer 2020.Neutral HULIS(HULIS-n),acidic HULIS(HULIS-a),and high-polarity water-soluble organic compounds(HP-WSOC)were analyzed to determine their carbon concentrations and measure their ultraviolet-visible absorption and infrared spectra.Of the three components,HULIS-n had the highest carbon content in both winter(3.29±1.45μg m^(-3))and in summer(1.38±1.10μg m^(-3)).The semi-quantitative results for the functional groups revealed that HP-WSOC was rich in carboxylic acids and had high aromaticity in winter,whereas HULIS-n was rich in carboxylic acids in summer.Moreover,HULJS-a was richer in nitrate esters and saturated aliphatic hydrocarbons in summer than in winter.The results for specific ultraviolet absorbance(SUVA)and E_(250)/E_(365) revealed that HULIS had higher molecular weight and aromaticity in winter than in summer.HULIS-n dominated in the total light absorption of HULIS+HP-WSOC in both winter(73.08%)and summer(48.57%).Overall,the results on the carbon content,optical properties,and functional groups of WSOCs with differing polarity can improve un-derstanding of environmental and climatic effects. | Xueting Yang Shasha Huang Dan Li Hongmei Xu Yaling Zeng Liu Yang Diwei Wang Ningning Zhang Junji Cao Zhenxing Shen | 2024 | Particuology2024,84,1: | 0 |
| 7 | Structural Control of the Getang Carlin-Type Gold Deposit in Southwest China显示文摘The Getang is a representative Carlin-type gold deposit in Southwest China.It has a proven reserve of about 30 tonnes at an average grade of 5.1 g/t Au.The orebodies occur as strat-abound lenses,and are structurally controlled by shallow NWW-and NE-trending fold-fault systems and the unconformity between the Upper and Middle Permian.In this study,the regional-and deposit-scale structural investigations,joints and finite strain measurements,and stress and dynamic analysis were conducted with an aim to reveal the structural process of the Getang gold deposit and clarify the relationship between the gold mineralization and structures.Three phases of deformation were identified in the deposit:(1)paleokarst was generated by a crustal uplift when the Youjiang Basin experienced extension at the end of the Middle Permian,laying the foundation for the unconformity;(2)the NW-trending structures were formed under a NNE-SSW compression during the Indochina-South China collision(Indosinian orogeny)in Triassic;(3)the NE-trending structures were generated or reactivated under a NW-SE-oriented compression during the Yanshanian intracontinental orogeny.The unconformity recorded two episodes of tectonic evolution in the NNE-SSW and NW-SE directions.Structural analyses and geochronology data suggest that the Getang gold deposit was formed as a result of tectonic transition from compression to extension during the Yanshanian intracontinental orogeny. | Guoping Zeng Xinlu Hu Diwei Luo Jianzhong Liu Shuzhen Yao Yongjie Jin | 2024 | Journal of Earth Science2024,35,2: | 0 |
| 8 | Electron-beam-driven anomalous Doppler effects in Smith–Purcell radiation显示文摘The interaction between electrons and matter is an effective means of light emission,through mechanisms including Cherenkov radiation and Smith–Purcell radiation(SPR).In this study,we show that the superlight inverse Doppler effects can be realized in reverse Smith–Purcell radiation excited by a free electron beam with a homogeneous substrate.In particular,we find that two types of anomalous SPR exist in the homogenous substrate:special SPR and reverse SPR.Our results reveal that the electron velocity can be tuned to simultaneously excite different combinations of normal SPR,special SPR,and reverse SPR.The proposed manifold light radiation mechanism can offer greater versatility in controlling and shaping SPR. | XIAOQIUYAN ZHANG TIANYU ZHANG ZHUOCHENG ZHANG XINGXING XU DIWEI LIU ZHAOYUN DUAN YANYU WEI YUBIN GONG LIANG JIE WONG MIN HU | 2024 | Photonics Research2024,12,1: | 0 |