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33篇 您的检索式：作者名="LOIRE R"

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	题名	作者	年代	出处	被引量
1	Value of a newly sequenced bacterial genome显示文摘Next-generation sequencing(NGS) technologies have made high-throughput sequencing available to medium- and small-size laboratories, culminating in a tidal wave of genomic information. The quantity of sequenced bacterial genomes has not only brought excitement to the field of genomics but also heightened expectations that NGS would boost antibacterial discovery and vaccine development. Although many possible drug and vaccine targets have been discovered, the success rate of genome-based analysis has remained below expectations. Furthermore, NGS has had consequences for genome quality, resulting in an exponential increase in draft(partial data) genome deposits in public databases. If no further interests are expressed for a particular bacterial genome, it is more likely that the sequencing of its genome will be limited to a draft stage, and the painstaking tasks of completing the sequencing of its genome and annotation will not be undertaken. It is important to know what is lost when we settle for a draft genome and to determine the 'scientific value' of a newly sequenced genome. This review addresses the expected impact of newly sequenced genomes on antibacterial discovery and vaccinology. Also, it discusses the factors that could be leading to the increase in the number of draft deposits and the consequent loss of relevant biological information.	Eudes GV Barbosa Flavia F Aburjaile Rommel TJ Ramos Adriana R Carneiro Yves Le Loir Jan Baumbach Anderson Miyoshi Artur Silva Vasco Azevedo	2014	World Journal of Biological Chemistry2014，5，2：	7
2	Circumstances of death and microscopic observations in a series of 200 cases of sudden death arrhythmogenic right ventricular cardiomyopathy and/or dysplasia 显示文摘	Tabib A Loire R Chalabreysse L	2003	Circulation2003，108，24：	1
3	Clinical presentation of left at rialcardiac myxoma:a series of 112 consecutive cases显示文摘	Duhaut P Loire R	2001	Medicine2001，80，：	1
4	Contralateral haemorrhagic pulmonary metastases('choriocarcinoma syndrome') after pneumonectomy for primary pulmonary choriocarcinoma显示文摘	Berger N Loire R	1994	Thorax1994，49，：	1
5	Circumstances of death and gross and microscopic observations in a series of 200 cases of sudden death associated with arrhythmogenic right ventricular cardiomyopathy and/or dysplasia显示文摘	Tabib A Loire R Chalabreysse L	2003	Circulation2003，108，24：	1
6	Small-vessel vasculifis surrounding an uninflamed temporal artery: a new diagnostic criterion for polymyalgia rheumatiea 显示文摘	Chatelain D Duhaut P Loire R	2008	Arthritis Rheum2008，58，8：	1
7	Clinical presentation of left atrial cardiac myxoma显示文摘	Pinede L Duhaut P Loire R	2001	Medicine2001，80，3：	1
8	Pathology of benign vocal fold lesion显示文摘	Loire R Bouchayer M Cornut G	1988	Ear Nos Throat1988，67，5：	1
9	Mesenchymal cystic hamartoma of the lung in Cowden' s disease 显示文摘	Cottin V Thomas L Loire R	2003	Respir Med2003，97，2：	1
10	Pathology of benign vocal fold lesion显示文摘	Loire R	1988	Ear Nose Throat J1988，57，2：	1
11	Epidermoid cysts,sulci,and mucosal bridges of the true vocal cord:A report of 157 cases显示文摘	Cornut G Bouchayer M Witzig E Roch JB Loire R	1985	The Laryngoscope1985，95，9：	1
12	On the release and half-life of S100B protein in the peripheral blood of melanoma patients显示文摘	Ghanem G Loir B Morandini R	2001	Int J Cancer2001，94，：	1
13	Clinical presentation of left atrialcardiac myxoma: a series of 112 consecutive cases显示文摘	Pinede L Duhaut P Loire R	2001	Medicine (Baltimore)2001，80，3：	1
14	Giant Lambl excres- cences: an unusual source of cerebral embolism 显示文摘	Nighoghossian N Derex L Loire R	1997	Arch Neurol1997，54，：	1
15	Clinical presentation of left atrial cardiac myxoma: a series of 112 consecutive cases显示文摘	Pinede L Duhaut P Loire R	2001	Medicine2001，80，3：	1
16	Circumstances of death and gross and microscopic observations in a series of 200 cases of sudden death as- sociated with arrhythmogenic right ventricular cardio- myopathy and/or dysplasia 显示文摘	TABIB A LOIRE R CHALABREYSSE L	2003	Circulation2003，108，：	1
17	Aggressive primary mediastinal non-Hodgkin's lymphomas:a study of 29 cases显示文摘	Etienne B Guillaud PH Loire R		0，，：	1
18	Clinical presentationof left atrial cardiac myxoma: a series of 112 consecutive cases显示文摘	Pinede L Duhaut P Loire R	2001	Medicine2001，80，3：	1
19	Idiopathic bronchiolitis obli- terans organizing pneumonia: definition of characteristic clinical profiles in a series of 16 patients显示文摘	Cordier J F Loire R Brune J	1989	Chest1989，96，5：	1
20	Clincal presentation of left atrialardiac myxoma: a series of 112 consecutive cases显示文摘	Pinede L Duhaut P Loire R	2001	Medicine(Baltimore)2001，80，3：	1

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